Browse our FOSL2 Proteins (FOSL2)

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FOS-Like Antigen 2 Proteins (FOSL2)
On are 11 FOS-Like Antigen 2 (FOSL2) Proteins from 5 different suppliers available. Additionally we are shipping FOSL2 Antibodies (139) and FOSL2 Kits (6) and many more products for this protein. A total of 166 FOSL2 products are currently listed.
FOSL2, fra-2, fra2, PLB1, wu:fl17h04, xx:fl17h04, zgc:158347
list all proteins Gene Name GeneID UniProt
FOSL2 2355 P15408
FOSL2 14284 P47930
FOSL2 25446 P51145

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FOSL2 Proteins (FOSL2) by Origin

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More Proteins for FOSL2 Interaction Partners

Human FOS-Like Antigen 2 (FOSL2) interaction partners

  1. FOSL2 is a direct target of miR (show MLXIP Proteins)-597 in breast cancer cells.

  2. The binding and expression of c-Fos/Fra-2 increased as a function of severity of tongue lesions, yet selective participation of c-Jun appears to promote poor differentiation and aggressive tumorigenesis.

  3. FOSL2 facilitates TGF-beta1 (show TGFB1 Proteins)-induced migration by interaction with Smad3 (show SMAD3 Proteins) in non-small cell lung cancer.FOSL2 positively regulates TGF-beta1 (show TGFB1 Proteins) signalling .

  4. FRA2 is a STAT5 (show STAT5A Proteins) target gene regulated by IL-2 (show IL2 Proteins) in human CD4 (show CD4 Proteins) T cells.

  5. we show that the suppression was mediated, at least in part, by a suspension culture-driven decrease in the levels of two members of the AP1 (show FOSB Proteins) transcription factor complex, c-Jun (show JUN Proteins) and Fra2

  6. SOX4 is a direct target gene of FRA-2 and induces expression of HDAC8 (show HDAC8 Proteins) in adult T-cell leukemia/lymphoma.

  7. This study suggests that Fra-2 transgenic mice as an animal model of systemic sclerosis-associated pulmonary arterial hypertension display main characteristic features of the human disease.

  8. results demonstrate the presence of a common oncogenic cascade initiated by FRA2/JUND (show JUND Proteins) in CCR4 (show CCR4 Proteins)-expressing mature T-cell malignancies such as ATLL and CTCLs

  9. FOSL2 is a critical regulator of leptin (show LEP Proteins) expression in adipocytes

  10. Results suggest that Fra-2 protein may be more effective than ATF-2 (show ATF2 Proteins) protein in cyst formation originated from epithelial cells of dental follicles.

Mouse (Murine) FOS-Like Antigen 2 (FOSL2) interaction partners

  1. Data show that Fos-Related Antigen-2 (Fra-2) is a key upstream regulator of forkhead box O1 (Foxo1 (show FOXO1 Proteins)) and interferon regulatory factor 4 (Irf4 (show IRF4 Proteins)) expression and influences proliferation and differentiation of B cells at multiple stages.

  2. Deletion of Fra-2 leads to increased PPARgamma2 (show PPARG Proteins) expression and adipocyte differentiation as well as increased adipocyte apoptosis through upregulation of hypoxia-inducible factors.

  3. Osteoblast-specific expression of Fra-2/AP-1 (show JUN Proteins) controls adiponectin (show ADIPOQ Proteins) and osteocalcin (show BGLAP Proteins) expression and affects metabolism.

  4. Cytokine-mediated Fra-2 expression and stabilization is linked to regulation of myogenic progenitor cells.

  5. AP-1 (show JUN Proteins) composed with JunD (show JUND Proteins) and Fra2 protein plays a primary role in enhancing the transcription level of the CD11c (show ITGAX Proteins) gene in dendritic cells

  6. FOSL2 is a critical regulator of leptin (show LEP Proteins) expression in adipocytes

  7. Identify Fra-2 as an O(2)-sensitive transcriptional regulator of inducible TGFbeta (show TGFB1 Proteins) expression and position Fra-2 as an important player in reoxygenation-induced myocardial fibrosis.

  8. These findings reveal a novel function of Fra-2/AP-1 (show JUN Proteins) as a positive regulator of bone and matrix formation in mice and humans.

  9. Since transgenic overexpression of Fra-2 causes not only fibrosis but also vascular disease, Fra-2 might be an interesting novel candidate for molecular-targeted therapies for systemic sclerosis.

  10. AP-1 transrepressing retinoic acid does not deplete coactivators or AP-1 monomers but may target specific Jun or Fos containing dimers

Zebrafish FOS-Like Antigen 2 (FOSL2) interaction partners

  1. Fos-like antigen 2 (Fosl2), potentiates the rate of myocardial accretion from the zebrafish second heart field.

FOSL2 Protein Profile

Protein Summary

The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.

Alternative names and synonyms associated with FOSL2

  • FOS-like antigen 2 (FOSL2)
  • FOS-like antigen 2 (LOC100220040)
  • FOS-like antigen 2 (LOC100347042)
  • fos-like antigen 2 (Fosl2)
  • fos-like antigen 2 (fosl2)
  • FOSL2 protein
  • fra-2 protein
  • fra2 protein
  • PLB1 protein
  • wu:fl17h04 protein
  • xx:fl17h04 protein
  • zgc:158347 protein

Protein level used designations for FOS-Like Antigen 2 Proteins (FOSL2)

fos-related antigen 2 , FOS-like antigen 2 , FRA-2 , phospholipase B1

703068 Macaca mulatta
742240 Pan troglodytes
100220040 Taeniopygia guttata
100347042 Oryctolagus cuniculus
2355 Homo sapiens
14284 Mus musculus
25446 Rattus norvegicus
558921 Danio rerio
421416 Gallus gallus
608412 Canis lupus familiaris
509889 Bos taurus
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