Browse our anti-Hypocretin (Orexin) Receptor 1 (HCRTR1) Antibodies

Full name:
anti-Hypocretin (Orexin) Receptor 1 Antibodies (HCRTR1)
On www.antibodies-online.com are 80 Hypocretin (Orexin) Receptor 1 (HCRTR1) Antibodies from 18 different suppliers available. Additionally we are shipping Hypocretin (Orexin) Receptor 1 Kits (10) and Hypocretin (Orexin) Receptor 1 Proteins (4) and many more products for this protein. A total of 101 Hypocretin (Orexin) Receptor 1 products are currently listed.
Synonyms:
HCRTR1, Hctr1, Ox1r
list all antibodies Gene Name GeneID UniProt
HCRTR1 3061 O43613
HCRTR1 230777 P58307
HCRTR1 25593 P56718

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Most Popular Reactivities for anti-Hypocretin (Orexin) Receptor 1 (HCRTR1) Antibodies

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All available anti-Hypocretin (Orexin) Receptor 1 Antibodies

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Top referenced anti-Hypocretin (Orexin) Receptor 1 Antibodies

  1. Human Polyclonal HCRTR1 Primary Antibody for EIA, WB - ABIN953936 : Peltonen, Akerman, Bart: A role for PKD1 and PKD3 activation in modulation of calcium oscillations induced by orexin receptor 1 stimulation. in Biochimica et biophysica acta 2010 (PubMed)
    Show all 5 references for 953936

  2. Human Polyclonal HCRTR1 Primary Antibody for ELISA, WB - ABIN1536076 : Sakurai, Amemiya, Ishii, Matsuzaki, Chemelli, Tanaka, Williams, Richardson, Kozlowski, Wilson, Arch, Buckingham, Haynes, Carr, Annan, McNulty, Liu, Terrett, Elshourbagy, Bergsma, Yanagisawa: Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. in Cell 1998 (PubMed)
    Show all 2 references for 1536076

  3. Human Polyclonal HCRTR1 Primary Antibody for IF, ELISA - ABIN1535973 : Olafsdóttir, Rye, Scammell, Matheson, Stefánsson, Gulcher: Polymorphisms in hypocretin/orexin pathway genes and narcolepsy. in Neurology 2001 (PubMed)
    Show all 2 references for 1535973

  4. Dog (Canine) Polyclonal HCRTR1 Primary Antibody for EIA, WB - ABIN783920 : Petersén, Gil, Maat-Schieman, Björkqvist, Tanila, Araújo, Smith, Popovic, Wierup, Norlén, Li, Roos, Sundler, Mulder, Brundin: Orexin loss in Huntington's disease. in Human molecular genetics 2004 (PubMed)

More Antibodies against Hypocretin (Orexin) Receptor 1 Interaction Partners

Human Hypocretin (Orexin) Receptor 1 (HCRTR1) interaction partners

  1. G-protein-dependency of OX1 (show NQO1 Antibodies) receptor signalling

  2. Several single nucleotide polymorphisms (SNPs) in HCRTR2 (show HCRTR2 Antibodies) were nominally associated with Antipsychotic-induced weight gain (AIWG) in patients of European ancestry treated with either clozapine or olanzapine. None of the SNPs in HCRTR1 were associated with AIWG.

  3. Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation is highly unlikely to be caused by mutations in the exons of the HCRTR1 gene.

  4. This study determined structures of OX1R bound to the OX1R-selective antagonist SB-674042 and the dual antagonist suvorexant at 2.8-A and 2.75-A resolution.

  5. the orexinA/OX1 (show NQO1 Antibodies) receptor axis has a significant pro-survival function in adrenal cells.

  6. OX1R signaling can attenuate KOR (show OPRK1 Antibodies)-mediated reduction of cellular cAMP levels while enhancing KOR (show OPRK1 Antibodies)-mediated beta-arrestin recruitment and p38 (show CRK Antibodies) activation.

  7. OX1R and KOR (show OPRK1 Antibodies) heterodimerize, and this heterodimer associates with Galphas (show GNAS Antibodies), leading to increased protein kinase A (PKA) signaling pathway activity, including upregulation of intracellular cAMP levels.

  8. Results from homology and docking modeling show two alternative binding modes for orexin-A into orexin 1 receptor in concordance with what is known of G protein coupled receptors activation in general and the mutational data.

  9. Data suggest that interaction between the nociceptin/nociceptin (show PNOC Antibodies) receptor (show OPRL1 Antibodies) system and the orexin/orexin (show OX Antibodies) receptor system in neurons of the hypothalamus positively and negatively modulate complex and integrated responses to stress. [REVIEW]

  10. Orexin A upregulates the protein expression of OX1R and enhances the proliferation of SGC (show SGCB Antibodies)-7901 gastric cancer cells through the ERK (show EPHB2 Antibodies) signaling pathway.

Mouse (Murine) Hypocretin (Orexin) Receptor 1 (HCRTR1) interaction partners

  1. Results thus suggest that type 1 diabetes mellitus impairs testicular steroidogenesis and glucose homeostasis through inhibition of orexin A/OX1R signaling cascade due to decreased OX1R expression in adult mice, thereby affecting germ cell survival and their proliferation in the testis.

  2. Binding of OXA to OX1R is important for the development of the testis.

  3. Study demonstrated that activation of the OX1 (show NQO1 Antibodies) receptor in the ventrolateral periaqueductal gray of mice can initiate an endocannabinoid-CB1 (show CNR1 Antibodies) receptor-mediated analgesia. Activation of the OX2 receptor (show CD200R1 Antibodies) in the ventrolateral periaqueductal gray was also antinociceptive but this antinociceptive effect is CB1 (show CNR1 Antibodies) receptor-independent.

  4. Elevation levels of OX1R and OX2R (show CD200R1 Antibodies) following experimental autoimmune encephalomyelitis induction suggest that alteration in orexinergic system may involve in pathogenesis of multiple sclerosis.

  5. Study provides pharmacological and molecular evidence indicating, respectively, a role for OXR1 (show OXR1 Antibodies) signaling in ethanol and saccharin binge-like drinking

  6. orexin (show OX Antibodies) activation of OX1R in the bone locally suppresses bone formation and enhances bone resorption by lowering osseous ghrelin (show GHRL Antibodies) expression.

  7. findings demonstrate that Hcrtr-1 modulates the reinforcing properties of cannabinoids.

  8. The transcripts for the Orx1 (show OR13H1 Antibodies) and Orx2 receptors diverged in the basolateral amygdala with Orx1 (show OR13H1 Antibodies) increasing and Orx2 decreasing in animals that were susceptible to the chronic defeat.

  9. more severe depressive behavior was associated with reduced hippocampal orexin (show OX Antibodies) expression, contrasted with increased orexin (show OX Antibodies) plus Orx1 (show OR13H1 Antibodies) receptor mRNA expression in the amygdala.

  10. data demonstrate that hypocretin (show OX Antibodies) signaling acting on Hcrtr-1 in the PVN plays a crucial role in the expression of nicotine withdrawal.

Cow (Bovine) Hypocretin (Orexin) Receptor 1 (HCRTR1) interaction partners

  1. These data confirmed expression of orexin (show OX Antibodies) and its two receptors in the bovine adrenal gland.

  2. first evidence for the expression of oxA and ox1R in the vestibular glands of mammalian genital tract

Pig (Porcine) Hypocretin (Orexin) Receptor 1 (HCRTR1) interaction partners

  1. 39 of 41 in: Acta (show ACTA1 Antibodies) Histochem. 2014 Jan;116(1) Orexin (show OX Antibodies) 1 receptor is expressed in the seminiferous tubules of boar testis.

  2. Immunoreactivity (IR) for both orexins A and B (OXA and OXB), and cognate receptors (OX1R and OX2R (show HCRTR2 Antibodies)) were identified only in the excretory striated (show NSDHL Antibodies) ducts of the MSG while acinar cells were not immunoreactive.

  3. Data demonstrated the presence of OX1R and OX2R (show HCRTR2 Antibodies) genes and proteins in the ovary of the pig and the impact of the hormonal milieu on the expression of both receptors.

  4. expression of OX1R and Ox2R (show HCRTR2 Antibodies) in hypothalamus during oestrous cycle; evidence OX1R and OX2R (show HCRTR2 Antibodies) mRNAs and proteins occur in hypothalamic structures engaged in control of reproduction; indicate dependence of OXR expression on endocrine reproductive state

  5. findings provide the first evidence that orexin (show OX Antibodies) receptors 1 and 2 messenger RNAs and proteins occur in the pituitary of the pig and indicate the dependence of orexin (show OX Antibodies) receptor expression on the endocrine reproductive state

Hypocretin (Orexin) Receptor 1 (HCRTR1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.

Alternative names and synonyms associated with Hypocretin (Orexin) Receptor 1 (HCRTR1)

  • hypocretin (orexin) receptor 1 (HCRTR1) antibody
  • orexin receptor 1 (LOC100352294) antibody
  • hypocretin (orexin) receptor 1 (Hcrtr1) antibody
  • orexin receptor 1 (LOC443167) antibody
  • orexin receptor type 1-like (LOC100855896) antibody
  • HCRTR1 antibody
  • Hctr1 antibody
  • Ox1r antibody

Protein level used designations for HCRTR1

orexin receptor 1 , hypocretin (orexin) receptor 1 , orexin receptor type 1-like , hypocretin receptor 1 , hypocretin receptor type 1 , hypocretin receptor-1 , orexin receptor type 1 , orexin receptor-1 , ox-1-R , ox1-R , ox1r , ox1R

GENE ID SPECIES
469261 Pan troglodytes
487320 Canis lupus familiaris
705914 Macaca mulatta
100056164 Equus caballus
100352294 Oryctolagus cuniculus
100412613 Callithrix jacchus
100443700 Pongo abelii
100484029 Ailuropoda melanoleuca
100587464 Nomascus leucogenys
3061 Homo sapiens
230777 Mus musculus
25593 Rattus norvegicus
282248 Bos taurus
387287 Sus scrofa
443167 Ovis aries
100855896 Canis lupus familiaris
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