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UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 ELISA Kits (B4GALT1)
On are 29 UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) ELISA Kits from 11 different suppliers available. Additionally we are shipping B4GALT1 Antibodies (35) and B4GALT1 Proteins (7) and many more products for this protein. A total of 78 B4GALT1 products are currently listed.
B-1,4-GalT, B-1,4-GalT1, b4Gal-T1, beta-1,4-GalT, beta-1,4-GalT1, beta4Gal-T1, CDG2D, GalT, Ggtb, Ggtb2, GT1, GTB
list all ELISA KIts Gene Name GeneID UniProt
B4GALT1 2683 P15291
B4GALT1 14595 P15535
B4GALT1 24390  

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Human UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) interaction partners

  1. demonstrated that ZFX is aberrantly expressed in multiple human leukemic cells and it modulates the growth and drug response of leukemic cells partially via B4GALT1, which suggests that ZFX is a new regulator of leukemic cells and warrants intensive investigations on this 'stemness' regulator in these deadly diseases

  2. High B4GALT1 expression is associated with aging.

  3. We suggest that the unique expression patterns for the B4GALT1 in normal and malignant tissues are controlled by a differential usage of 5'-B4GALT1 regulatory units along with a post-transcriptional regulation by the antisense RNA

  4. Human chorionic gonadotropin provides a mechanism to bridge embryo to endometrium through beta1,4-GalT (show GALT ELISA Kits).

  5. HS5 cells had significantly enhanced levels of bisecting N-glycans (catalyzed by MGAT3 (show MGAT3 ELISA Kits) whereas HS27a cells had enhanced levels of Galbeta1,4GlcNAc.

  6. B4GALT1 and B4GALT5 (show B4GALT5 ELISA Kits), two members of B4GALT (show B4GALNT2 ELISA Kits) gene family, are involved in the development of multidrug resistance of human leukemia cells.

  7. the glycogene B4GALT1 represent a valuable candidate biomarker of invasive phenotype of colorectal cancer.

  8. RNAi-mediated knockdown of beta1,4GT1 increased the levels of EGFR (show EGFR ELISA Kits) dimerization and phosphorylation. These data suggest that cell surface beta1,4GT1 interacts with EGFR (show EGFR ELISA Kits) and inhibits EGFR (show EGFR ELISA Kits) activatio

  9. estrogen regulates the expression of B4GALT1 through the direct binding of ER-alpha (show ESR1 ELISA Kits) to ERE; the expressed B4GALT1 plays a crucial role in the proliferation of MCF-7 cells through its activity as a membrane receptor.

  10. Osteopontin increases the expression of beta1, 4-Galactosyltransferase-I and promotes adhesion in human RL95-2 cells, the activity critical for embryo implantation.

Mouse (Murine) UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) interaction partners

  1. The loss of the long GalT (show GALT ELISA Kits)-I isoform also leads to a loss of actin stress fibers, focal adhesions and rac (show AKT1 ELISA Kits) GTPase (show RACGAP1 ELISA Kits) activation.

  2. beta4GalT1 can regulate N-glycans of CXCR3 (show CXCR3 ELISA Kits) in RA. N-glycans of CXCR3 (show CXCR3 ELISA Kits) affects CXCL10 (show CXCL10 ELISA Kits)/CXCR3 (show CXCR3 ELISA Kits) ligand-binding which enhancing fibroblast-like synoviocytes invasion.

  3. Beta 1,4-galactosyltransferase I possibly regulate mutual uterus-embryo adhesion and embryo implantation by regulating cell surface Le(Y) glycan expression.

  4. revealed increased expression of polylactosamines on B4galt1(+/-) B cells and macrophages, compared with B4galt1(+/+) cells

  5. beta4GalT-I is a major galactosyltransferase (show a3GALT2 ELISA Kits) responsible for selectin-ligand biosynthesis and that inflammatory responses of beta4GalT-I-deficient mice are impaired because of the defect in selectin-ligand biosynthesis.

  6. the beta4-galactosyltransferase (show a3GALT2 ELISA Kits)-1 coding sequence does not contain functional elements that affect the intrinsic stability of this mRNA

  7. regulation of expression by focal adhesion kinase

  8. Deoxygenated disaccharide analogs as specific inhibitors of beta1-4-galactosyltransferase (show a3GALT2 ELISA Kits) 1 and selectin-mediated tumor metastasis.

Cow (Bovine) UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) interaction partners

  1. Hypothesized that engineering B4GALT1 to block cleavage and secretion would enhance its retention and its function; to test this hypothesis, replaced CTS (show TTR ELISA Kits) domains of bovine B4GALT1 with those from human FUT7 (show FUT7 ELISA Kits), which is not cleaved and secreted.

  2. Crystal structure of mutant Met344His beta4Gal-T1 defined at 2.3 angstrom resolution reveals that the N-acetylglucosamine residue at nonreducing end of chitobiose makes extensive hydrophobic interactions with highly conserved tyrosine-286 of beta4Gal-T1.

B4GALT1 Antigen Profile

Antigen Summary

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose\; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase.

Alternative names and synonyms associated with B4GALT1

  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (B4GALT1) Elisa Kit
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (B4galt1) Elisa Kit
  • B-1,4-GalT Elisa Kit
  • B-1,4-GalT1 Elisa Kit
  • b4Gal-T1 Elisa Kit
  • beta-1,4-GalT Elisa Kit
  • beta-1,4-GalT1 Elisa Kit
  • beta4Gal-T1 Elisa Kit
  • CDG2D Elisa Kit
  • GalT Elisa Kit
  • Ggtb Elisa Kit
  • Ggtb2 Elisa Kit
  • GT1 Elisa Kit
  • GTB Elisa Kit

Protein level used designations for B4GALT1

UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1 , UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1 , beta-1,4-GalTase 1 , beta-1,4-galactosyltransferase 1 , glycoprotein-4-beta-galactosyltransferase 2 , lactose synthase , b1,4-Galactosyltransferase I , galactosyltransferase 2 beta 1, 4 , glycoprotein galactosyltransferase beta 1, 4 , Glycoprotein-4-beta-galactosyltransferase 2 , b4Gal-T1 , beta4Gal-T1 , beta-galactosyltransferase 2 (glycoprotein) , UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1

2683 Homo sapiens
14595 Mus musculus
24390 Rattus norvegicus
281781 Bos taurus
100345726 Oryctolagus cuniculus
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