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anti-Human CSGALNACT1 Antibodies:
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Cow (Bovine) Polyclonal CSGALNACT1 Primary Antibody for WB - ABIN2782962
Clark, Edwards, Peterson, Clifton, Thompson, Sasaki, Suzuki, Kikuchi, Watabe, Kawakami, Sugano, Elgar, Johnson: Fugu ESTs: new resources for transcription analysis and genome annotation. in Genome research 2003
Show all 2 references for 2782962
Cow (Bovine) Polyclonal CSGALNACT1 Primary Antibody for WB - ABIN2782963
Sakai, Kimata, Sato, Gotoh, Narimatsu, Shinomiya, Watanabe: Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage. in The Journal of biological chemistry 2007
CSGalNAcT-1 and Hapln-1 (show HAPLN1 Antibodies) may play important roles in the pathogenesis of Kashin-Beck disease and osteoarthritis.
CSGalNAcT-1 exhibited higher enzymatic efficiency toward monosulfated trisaccharides substituted at C4 or C6 position of Gal1, and at C6 of Gal2 compared with the unsulfated oligosaccharide.
CSGALNACT1 missense mutations are associated with neuropathies.
These results suggest that this enzyme has N-acetylgalactosaminyltransferase (show B4GALNT2 Antibodies) activity in both the elongation and initiation of chondroitin sulfate synthesis.
CSGalNAcT-1 is necessary for normal levels of endochondral ossification, and the decrease in CS amount in the growth plate by its absence causes a rapid catabolism of aggrecan (show ACAN Antibodies).
Results suggest that CSGalNAcT1 is required for normal CS production in developing cartilage.
Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage.
chondroitin beta1,4 N-acetylgalactosaminyltransferase
, chondroitin sulfate N-acetylgalactosaminyltransferase 1
, chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1
, beta1,4 N-acetylgalactosaminyltransferase