Browse our EXT1 (EXT1) ELISA Kits

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Exostosin 1 ELISA Kits (EXT1)
On are 16 Exostosin 1 (EXT1) ELISA Kits from 7 different suppliers available. Additionally we are shipping EXT1 Antibodies (57) and EXT1 Proteins (8) and many more products for this protein. A total of 89 EXT1 products are currently listed.
AA409028, EXT, LGCR, LGS, TRPS2, TTV, xext1
list all ELISA KIts Gene Name GeneID UniProt
EXT1 14042 P97464
EXT1 2131 Q16394
Rat EXT1 EXT1 299907  

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Top referenced EXT1 ELISA Kits

  1. Human EXT1 ELISA Kit for Sandwich ELISA - ABIN421829 : Khoontawad, Hongsrichan, Chamgramol, Pinlaor, Wongkham, Yongvanit, Pairojkul, Khuntikeo, Roytrakul, Boonmars, Pinlaor: Increase of exostosin 1 in plasma as a potential biomarker for opisthorchiasis-associated cholangiocarcinoma. in Tumour biology 2014 (PubMed)

More ELISA Kits for EXT1 Interaction Partners

Zebrafish Exostosin 1 (EXT1) interaction partners

  1. the three zebrafish ext1 genes encode proteoglycan (show Vcan ELISA Kits) modifying enzymes and have distinct relationships to somitic Sonic hedgehog (show SHH ELISA Kits) signaling

Mouse (Murine) Exostosin 1 (EXT1) interaction partners

  1. reactivating SHH (show SHH ELISA Kits) signaling in mutant lungs rescued the tip dilation phenotype and attenuated FGF signaling. Importantly, the reduced SHH (show SHH ELISA Kits) signaling activity did not appear to be caused by decreased Shh (show SHH ELISA Kits) expression or protein stability; instead, biologically active form of SHH (show SHH ELISA Kits) proteins were reduced in both the Ext1 mutant epithelium and surrounding wild type mesenchymal cells.

  2. Normal heparin sulfate levels and Ext1 activity in the stromal microenvironment and hematopoietic stem cells are required for the transplant engraftment following non-myeloablative conditioning.

  3. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  4. Ext genes and heparan sulfate are needed to establish and maintain perichondrium's phenotype and border function.

  5. Levels of Ext1 and HPSE (show HPSE ELISA Kits) influence the motility of FBJ osteosarcoma cells.

  6. stromal Ext1-levels modulate tumor cell proliferation and affect the interstitial fluid pressure in a 3-D spheroid model.

  7. The study indicates that formation of stereotypic exostoses requires a significant, but not complete, loss of Ext expression.

  8. local Ext1 expression and heparan sulfate production are needed to maintain the phenotype and function of joint-forming cells.

  9. Ext1 has a role in regulation of bone morphogenic protein signaling and skeletal defects

  10. inactivation of Ext1 in a small fraction of chondrocytes is sufficient for the development of osteochondromas and other skeletal defects associated with multiple hereditary exostoses

Human Exostosin 1 (EXT1) interaction partners

  1. EXT1, a gene not previously linked to acute lymphoblastic leukemia via mutations, is a common interactor of NOTCH1 (show NOTCH1 ELISA Kits) and FBXW7 (show FBXW7 ELISA Kits) regulating the NOTCH (show NOTCH1 ELISA Kits) pathway in an FBXW7 (show FBXW7 ELISA Kits)-dependend manner.

  2. A novel heterozygous point mutation (c.1164+1G to A) at the 5'splice sites of intron 3 of the EXT1 gene is associated with multiple osteochondroma.

  3. EXT1 is up regulated in patients after chronic rhinosinusitis, developing osteitis.

  4. We report the discovery of a non-sense mutation in EXT2 (show EXT2 ELISA Kits) in an 11 (show DCAF7 ELISA Kits)-y-old boy diagnosed with multiple osteochondroma.

  5. We found that the prevalence of EXT1 mutations was greater than that of EXT2 mutations in Japanese multiple osteochondromas families.

  6. Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans

  7. EXT1 mutation is associated with multiple osteochondromatosis.

  8. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  9. there is a putative genetic connection between TCF7L2 and EXT in the context of Hereditary Multiple Exostoses

  10. loss of function of EXT1 subjects with hereditary multiple exostoses affects pancreatic insulin (show INS ELISA Kits) secretion capacity and development.

EXT1 Antigen Profile

Antigen Summary

This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses.

Alternative names and synonyms associated with EXT1

  • exostoses (multiple) 1b (ext1b) Elisa Kit
  • exostoses (multiple) 1 (Ext1) Elisa Kit
  • exostoses (multiple)-like 1 (EXTL1) Elisa Kit
  • exostosin 1 (EXT1) Elisa Kit
  • exostosin glycosyltransferase 1 (EXT1) Elisa Kit
  • exostosin glycosyltransferase 1 (Ext1) Elisa Kit
  • exostosin glycosyltransferase 1 (ext1) Elisa Kit
  • exostosin-1-like (LOC100537794) Elisa Kit
  • AA409028 Elisa Kit
  • EXT Elisa Kit
  • LGCR Elisa Kit
  • LGS Elisa Kit
  • TRPS2 Elisa Kit
  • TTV Elisa Kit
  • xext1 Elisa Kit

Protein level used designations for Exostosin 1 (EXT1) ELISA Kits

exostosin-1b , glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1b , multiple exostoses protein 1 homolog b , exostosin-1 , glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase , multiple exostoses protein 1 homolog , Heparan sulfate copolymerase , Multiple exostoses protein 1 homolog , exostosin 1 , exostoses-like 1 , Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase , exostoses (multiple) 1 , Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase , Langer-Giedion syndrome chromosome region , N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase , multiple exostoses protein 1 , putative tumor suppressor protein EXT1

497280 Danio rerio
14042 Mus musculus
100689334 Cricetulus griseus
100347418 Oryctolagus cuniculus
538602 Bos taurus
2131 Homo sapiens
299907 Rattus norvegicus
399115 Xenopus laevis
100537794 Danio rerio
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