Browse our Glypican 4 Proteins (GPC4)

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Glypican 4 Proteins (GPC4)
On www.antibodies-online.com are 21 Glypican 4 (GPC4) Proteins from 4 different suppliers available. Additionally we are shipping Glypican 4 Antibodies (128) and Glypican 4 Kits (39) and many more products for this protein. A total of 191 Glypican 4 products are currently listed.
Synonyms:
9530073D23Rik, AF311610, AI385680, AI661372, chunp6920, glypican-4, gpc4,, gpc4/6, gpc6, K-glypican, kny, knypek, wu:fc47a08, wu:fe05f10, Xgly4
list all proteins Gene Name GeneID UniProt
GPC4 2239 O75487
GPC4 317322  
GPC4 14735 P51655

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Glypican 4 Proteins (GPC4) by Origin

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Human Glypican 4 (GPC4) interaction partners

  1. According to behavioral studies, downregulation of Gpc4 by Gpc4 siRNA decreased spontaneous seizure frequency, while upregulation of Gpc4 by recombinant Gpc4 overexpression led to a converse result. These findings support the hypothesis that increased expression of Gpc4 in the brain is associated with epileptic seizures.

  2. Data suggest gender difference in circulating GPC4 levels in nonalcoholic fatty liver disease; GPC4 levels in women appear to correlate with cardiometabolic risk factors (adiposity/body fat distribution, insulin (show INS Proteins) resistance, and arterial stiffness).

  3. new function of miR (show MLXIP Proteins)-125a by targeting gene glypican-4 in cell growth process

  4. Findings establish that Gpc4 acts at the interface of extrinsic and intrinsic signal regulation to fine tune stem cell fate.

Mouse (Murine) Glypican 4 (GPC4) interaction partners

  1. Findings establish that Gpc4 acts at the interface of extrinsic and intrinsic signal regulation to fine tune stem cell fate.

  2. data identify glypicans as a family of novel astrocyte-derived molecules that are necessary and sufficient to promote glutamate (show GRIN1 Proteins) receptor clustering and receptivity and to induce the formation of postsynaptically functioning CNS synapses

  3. complex pattern of glypican-4 mRNA localization at embryonic days 7-10.5, including sites in the anterior forebrain neuroepithelium, branchial arches, optic and otic vesicles, limb buds and somites

Zebrafish Glypican 4 (GPC4) interaction partners

  1. the chaperon Wls (show WLS Proteins) and its ligands Wnt9a (show WNT9A Proteins) and Wnt5b (show WNT5B Proteins) are expressed in the ectoderm, whereas juxtaposed chondrocytes express Frzb (show FRZB Proteins) and Gpc4.

  2. A mutation in glypican4 leads to severe lateral line primordium migration defects. Glypican4 regulates the feedback loop between Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins)/Fgf signaling in the primordium redundantly with other HSPGs. A mutation in glypican4 affects primordium migration non cell-autonomously

  3. disruption of wls (show WLS Proteins) resulted in a significant loss of craniofacial bone, whereas lack of gpc4, wnt5b (show WNT5B Proteins) and wnt9a (show WNT9A Proteins) resulted in severely delayed endochondral ossification.

  4. novel mechanism for Wnt5b (show WNT5B Proteins) and Gpc4 regulation of chondrocyte behavior that is independent of the core Wnt (show WNT2 Proteins)/PCP (show PRCP Proteins) molecules and differs from their collaborative action of controlling cell movements during gastrulation

  5. glypican4 mutants do not have decreased proteolysis of ECM substrates, but instead have increased cell surface cadherin protein expression and increased intercellular adhesion.

  6. These findings implicate Gpc4 in the regulation of zebrafish cartilage and bone morphogenesis.

Glypican 4 (GPC4) Protein Profile

Protein Summary

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.

Alternative names and synonyms associated with Glypican 4 (GPC4)

  • glypican 4 (GPC4)
  • glypican 4 (gpc4)
  • glypican 4 (Gpc4)
  • 9530073D23Rik protein
  • AF311610 protein
  • AI385680 protein
  • AI661372 protein
  • chunp6920 protein
  • glypican-4 protein
  • gpc4, protein
  • gpc4/6 protein
  • gpc6 protein
  • K-glypican protein
  • kny protein
  • knypek protein
  • wu:fc47a08 protein
  • wu:fe05f10 protein
  • Xgly4 protein

Protein level used designations for Glypican 4 Proteins (GPC4)

glypican-4 , glypican 4 , glypican-4-like , dJ900E8.1 (glypican 4) , glypican proteoglycan 4 , fc47a08 , fe05f10

GENE ID SPECIES
100057156 Equus caballus
399356 Xenopus laevis
473788 Pan troglodytes
706665 Macaca mulatta
100084193 Ornithorhynchus anatinus
100126682 Xenopus (Silurana) tropicalis
100400754 Callithrix jacchus
100477894 Ailuropoda melanoleuca
100591343 Nomascus leucogenys
2239 Homo sapiens
317322 Rattus norvegicus
14735 Mus musculus
492144 Canis lupus familiaris
100156029 Sus scrofa
540179 Bos taurus
100722123 Cavia porcellus
100351609 Oryctolagus cuniculus
422234 Gallus gallus
101109518 Ovis aries
118437 Danio rerio
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