Browse our Heparanase (HPSE) ELISA Kits

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Heparanase ELISA Kits (HPSE)
On are 45 Heparanase (HPSE) ELISA Kits from 9 different suppliers available. Additionally we are shipping Heparanase Antibodies (194) and Heparanase Proteins (28) and many more products for this protein. A total of 272 Heparanase products are currently listed.
Hep, Hpa, HPA1, Hpr1, HPSE, HPSE1, HSE1, im:7144134

Top referenced Heparanase ELISA Kits

  1. Mouse (Murine) HPSE ELISA Kit for Sandwich ELISA - ABIN424453 : Hammond, Brandt, Dredge: PG545, a heparan sulfate mimetic, reduces heparanase expression in vivo, blocks spontaneous metastases and enhances overall survival in the 4T1 breast carcinoma model. in PLoS ONE 2013 (PubMed)
    Show all 3 references for 424453

  2. Human HPSE ELISA Kit for Sandwich ELISA - ABIN367248 : Zhang, Qing, Wang, Xu, Zhi, Park, Zhang, Chen: Syndecan-1 and Heparanase: Potential Markers for Activity Evaluation and Differential Diagnosis of Crohn's Disease. in Inflammatory bowel diseases 2013 (PubMed)

More ELISA Kits for Heparanase Interaction Partners

Human Heparanase (HPSE) interaction partners

  1. Results show that HPSE is upregulated in human glioma and seems to confer a growth advantage on glioma cells.

  2. under physiological pH and low levels of tissue factor (show F3 ELISA Kits), heparanase may exert a non-enzymatic function interacting and activating the inhibitory function of antithrombin (show SERPINC1 ELISA Kits).

  3. Heparanase has emerged as a major regulator of cancer by degrading heparan sulfate thereby influencing multiple signaling pathways that control gene expression, syndecan (show SDC1 ELISA Kits) shedding and cell behavior. (Review)

  4. The most common HPA genotypes among Saudis were HPA-1 a + b- (75%), HPA-2 (show HPSE2 ELISA Kits) a + b- (62%), HPA-3 a + b- (51.5%), HPA-4 a + b- (99%), HPA-5 (show ITGA2 ELISA Kits) a + b- (76.5%), HPA-6 a + b- (100%) and HPA-15 a + b + (50%). The prevalent allele among the HPA systems was (a), except in the HPA-15 system where the (b) allele was found in 52% of the subjects.

  5. heparanase activity is increased without changes in superoxide dismutase (show SOD1 ELISA Kits) activity in the granulocytes from patients with lupus nephritis and membranous nephropathy

  6. Heparanase up-regulated the expression of the blood coagulation initiator-tissue factor (show F3 ELISA Kits) (TF) and interacted with the tissue factor pathway inhibitor (TFPI (show TFPI ELISA Kits)) on the cell surface membrane of endothelial and tumor cells, leading to dissociation of TFPI (show TFPI ELISA Kits) and resulting in increased cell surface coagulation activity. [review]

  7. Heparanase procoagulant activity predicts post-surgery necrosis.

  8. Suggest heparanase is a promising, novel target for overcoming myeloma resistance to therapy and that targeting heparanase has the potential to prevent relapse in myeloma and possibly other cancers.

  9. expression of BRMS1 (show BRMS1 ELISA Kits) and/or HPA might be closely related to the carcinogenesis, clinical biological behaviors, and prognosis of gallbladder adenocarcinoma

  10. in colorectal adenomas, the heparanase-1 does not participate in syndecan-1 (show SDC1 ELISA Kits) degradation; the heparanase-2 (show HPSE2 ELISA Kits) does not stimulate syndecan-1 (show SDC1 ELISA Kits) degradation by the action of heparanase-1, and the heparanase-2 (show HPSE2 ELISA Kits) may be involved in the modulation of the heparanase-1 activity.

Mouse (Murine) Heparanase (HPSE) interaction partners

  1. eNOS (show NOS3 ELISA Kits) prevents heparanase induction and the development of proteinuria

  2. Data show that heparanase-1 (HPA-1) induced shedding of heparan sulfate chain from syndecan-1 (SDC-1 (show SDC1 ELISA Kits)) facilitated the release of vascular endothelial growth factor C (VEGF-C (show VEGFC ELISA Kits)) from SDC-1 (show SDC1 ELISA Kits)/VEGF-C (show VEGFC ELISA Kits) complex into the medium of hepatocarcinoma cell.

  3. the activation of intestinal heparanase contributes to intestinal injury during early sepsis by facilitating the destruction of mucosal epithelial glycocalyx and promoting inflammatory responses.

  4. Heparanase increases the inflammation in AGEs-stimulated macrophages through activating the RAGE (show AGER ELISA Kits)-NF-kappaB (show NFKB1 ELISA Kits) pathway. Heparanase driven inflammation from AGEs-stimulated macrophages increases the adherence of glomerular endothelial cells (GEnCs) and augments the permeability of GEnCs.

  5. heparanase contributes to allergen-induced eosinophil recruitment to the lung.

  6. Unfractionated heparin inhibits heparanase, and reverses the activation of NF-kappaB (show NFKB1 ELISA Kits) and MAPK P38 (show MAPK1 ELISA Kits) signaling pathways to attenuate inflammatory responses induced by sepsis. These results suggest that UFH

  7. Results show a critical role for heparanase in regulating the branching and invasive behavior of normal mammary epithelia which could be the result of its mutually reciprocal feedback with MMP-14 (show MMP14 ELISA Kits).

  8. Data suggest a potential mechanism of diabetic enteropathy, which is depending remarkably on syndecan-1 (Sdc1 (show SDC1 ELISA Kits)) and -beta-D-glucuronidase (show GUSB ELISA Kits) heparanase (HPSE).

  9. Findings identify a dual function for HPSE in malignant melanoma with a protumorigenic extracellular activity and a tumor-suppressive nuclear action.

  10. Studies in heparanase-deficient mice established its contributions to autophagy.

Pig (Porcine) Heparanase (HPSE) interaction partners

  1. These data suggest that porcine reproductive and respiratory syndrome virus activates NF-kappaB (show NFKB1 ELISA Kits) and cathepsin L (show CTSL ELISA Kits) to upregulate and process heparanase, and then the active heparanase cleaves heparan sulfate, resulting in viral release.

  2. during late gestation, the mRNA and HPSE levels were higher in Meishan placentae than Yorkshire pigs

  3. study of tissue expression profiles, polymorphisms of HPSE and HPSE2 (show HPSE2 ELISA Kits) genes and changes of their mRNA levels in porcine alveolar macrophages (PAMs) induced by PRRSV; upon stimulation in healthy piglets with PRRSV, HPSE mRNA was obviously upregulated, while HPSE2 (show HPSE2 ELISA Kits) mRNA did not induce a prominent change in PAMs

  4. our results support a critical role for heparanase in the development of vulnerable atherosclerotic plaques

  5. report molecular cloning and characterisation of heparanase mRNA in the porcine placenta throughout gestation.

Cow (Bovine) Heparanase (HPSE) interaction partners

  1. Suggest that high glucose is a potent stimulator of endothelial heparanase secretion.

  2. Lutropin (show LHB ELISA Kits) induces a transient increase in HPSE mRNA at specific times after its addition.

Heparanase (HPSE) Antigen Profile

Antigen Summary

Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Heparanase (HPSE)

  • heparanase (HPSE) Elisa Kit
  • heparanase (hpse) Elisa Kit
  • heparanase (Hpse) Elisa Kit
  • heparanase (LOC100101601) Elisa Kit
  • Hep Elisa Kit
  • Hpa Elisa Kit
  • HPA1 Elisa Kit
  • Hpr1 Elisa Kit
  • HPSE Elisa Kit
  • HPSE1 Elisa Kit
  • HSE1 Elisa Kit
  • im:7144134 Elisa Kit

Protein level used designations for Heparanase (HPSE) ELISA Kits

heparanase , endo-glucoronidase , heparanase-1 , endoglycosidase heparanase , heparanase-like

100061267 Equus caballus
563020 Danio rerio
100145320 Xenopus (Silurana) tropicalis
461206 Pan troglodytes
707583 Macaca mulatta
10855 Homo sapiens
15442 Mus musculus
64537 Rattus norvegicus
100101601 Oryctolagus cuniculus
100721886 Cavia porcellus
608707 Canis lupus familiaris
100271932 Sus scrofa
281230 Bos taurus
373981 Gallus gallus
101118612 Ovis aries
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