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Human Vcan ELISA Kit for Sandwich ELISA - ABIN365779
Zhang, Wu, Qu, Bai, Merrilees, Black: Pro-inflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lung. in Journal of cellular and molecular medicine 2012
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Human Vcan ELISA Kit for Sandwich ELISA - ABIN417271
Li, Wang, Wu, Quan, Ma, Yang, Wu, Wan: Tumor-produced versican V1 enhances hCAP18/LL-37 expression in macrophages through activation of TLR2 and vitamin D3 signaling to promote ovarian cancer progression in vitro. in PLoS ONE 2013
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The isolation and characterization of a cDNA encoding zebrafish dermacan, a novel member of hyaluronan (HA)-binding proteoglycans, which was termed after its characteristic expression in the zebrafish dermal bones.
Data show that expression of mRNAs for aggrecan (show ACAN ELISA Kits), collagen type II, and versican were significantly effected by the intervention.
Data show that biglycan (show BGN ELISA Kits), collagen type I, collagen type II, decorin (show DCN ELISA Kits), and versican were significantly affected by vibration duration, frequency, and amplitude.
Versican V0 and V1 isoforms were upregulated in the uterine leiomyomas of symptomatic versus asymptomatic women. Abundant cleaved versican was detected in leiomyoma and myometrium, as well as in myometrial and leiomyoma cell lines. VCAN siRNA did not effect cell proliferation, apoptosis, or smooth muscle markers, but reduced ESR1 (show ESR1 ELISA Kits) and PR-A (show PGR ELISA Kits) expression.
Lumican (show LUM ELISA Kits) and versican protein expression are associated with colorectal adenoma-to-carcinoma progression
Removal or knockdown of versican may be a possible therapeutic strategy for increasing deposition of insoluble elastin (show ELN ELISA Kits) and stimulating repair of elastic fibers in COPD (show ARCN1 ELISA Kits) lung.
human myeloma tumors displaying CD8 (show CD8A ELISA Kits)(+) infiltration/aggregates underwent VCAN proteolysis at a site predicted to generate a glycosaminoglycan-bereft N-terminal fragment.
versican decreases in follicular dermal papilla as an aging-associated change of human hair follicles
Data indicate that serum versican levels were significantly decreased in polycystic ovary syndrome (PCOS) patients, and that serum ADAMTS-1 (show ADAMTS1 ELISA Kits) (a disintegrin and metalloproteinase with thrombospondin motif-1) and versican levels were significantly and positively correlated with each other.
the G1 domain of versican can regulate the organization of pericellular hyaluronan and affect phenotype of cultured human dermal fibroblasts
Gene expression levels of three randomly selected DEGs (show DEGS1 ELISA Kits), VCAN, COL5A1 (show COL5A1 ELISA Kits) and KCNJ16 (show KCNJ16 ELISA Kits), were examined using RT-PCR in 10 ATC (show SRPK1 ELISA Kits) samples.. angiogenesis was activated by the high expression of CTHRC1 (show CTHRC1 ELISA Kits), VCAN and POSTN (show POSTN ELISA Kits), providing necessary nutrition for tumor cells
Results highlight an important role for versican in regulating the expression and assembly of elastin (show ELN ELISA Kits) and the phenotype of leiomyosarcoma cells.
Versican localizes to the nucleus in proliferating mesenchymal cells and suggest role in mitotic spindle organization during cell division.
Versican is produced by Trif (show RNF138 ELISA Kits)- and type I interferon (show IFNA ELISA Kits)-dependent signaling in macrophages and contributes to fine control of innate immunity in lungs.
Loss of Versican is associated with reduced Lung Inflammatory Response.
Pelvic irradiation increases versican expression in bladder and rectum.
Versican V1 overexpression induces a myofibroblast-like phenotype in cultured fibroblasts.
The data suggest that versican plays an important role in fundamental, overlapping cellular processes in lung development and infection.
Our results show that versican released from glioma promotes tumor expansion through glioma-associated microglial/macrophage TLR2 (show TLR2 ELISA Kits) signaling and subsequent expression of MT1-MMP (show MMP14 ELISA Kits).
Arylsulfatase B (show ARSB ELISA Kits) regulates versican expression by galectin-3 (show LGALS3 ELISA Kits) and AP-1 (show JUN ELISA Kits) mediated transcriptional effects.
Versican regulates the growth of leiomyosarcoma tumors.
The relationship between hyaluronan synthesis and levels of versican, fibronectin (show FN1 ELISA Kits) and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.
This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene.
chondroitin sulfate proteoglycan 2a
, chondroitin sulfate proteoglycan 2 (versican)
, chondroitin sulfate proteoglycan core protein 2
, glial hyaluronate-binding protein
, large fibroblast proteoglycan
, versican core protein
, chondroitin sulfate proteoglycan 2
, chondroitin sulfate proteoglycan 2b
, versican proteoglycan
, PG-M core protein
, Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M)
, heart defect
, versican core protein-like