Browse our anti-IL10RA (IL10RA) Antibodies

Full name:
anti-Interleukin 10 Receptor, alpha Antibodies (IL10RA)
On www.antibodies-online.com are 221 Interleukin 10 Receptor, alpha (IL10RA) Antibodies from 27 different suppliers available. Additionally we are shipping IL10RA Kits (21) and IL10RA Proteins (14) and many more products for this protein. A total of 264 IL10RA products are currently listed.
Synonyms:
AW553859, CD210, CD210a, CDw210, CDw210a, HIL-10R, IL-10R1, Il10r, IL10R1, IL10RA, mIL-10R
list all antibodies Gene Name GeneID UniProt
IL10RA 3587 Q13651
IL10RA 16154 Q61727
IL10RA 117539  

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anti-Human IL10RA Antibodies:

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Top referenced anti-IL10RA Antibodies

  1. Mouse (Murine) Monoclonal IL10RA Primary Antibody for FACS - ABIN119864 : Asseman, Mauze, Leach, Coffman, Powrie: An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. in The Journal of experimental medicine 1999 (PubMed)
    Show all 4 references for 119864

  2. Human Polyclonal IL10RA Primary Antibody for WB - ABIN616045 : Okwor, Liu, Beverley, Uzonna: Inoculation of killed Leishmania major into immune mice rapidly disrupts immunity to a secondary challenge via IL-10-mediated process. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 3 references for 616045

  3. Human Monoclonal IL10RA Primary Antibody for FACS - ABIN119837 : Liu, de Waal Malefyt, Briere, Parham, Bridon, Banchereau, Moore, Xu: The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor. in Journal of immunology (Baltimore, Md. : 1950) 1997 (PubMed)
    Show all 2 references for 119837

  4. Cow (Bovine) Polyclonal IL10RA Primary Antibody for WB - ABIN2782131 : Gasche, Grundtner, Zwirn, Reinisch, Shaw, Zdanov, Sarma, Williams, Foxwell, Gangl: Novel variants of the IL-10 receptor 1 affect inhibition of monocyte TNF-alpha production. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)

  5. Human Monoclonal IL10RA Primary Antibody for FACS, WB - ABIN4899662 : Beck, Zobel, Barber, Evans, Lezina, Allchin, Blades, Elliott, Lord, Ashworth, Porter, Wagner: Synthetic Lethal Screen Demonstrates That a JAK2 Inhibitor Suppresses a BCL6-dependent IL10RA/JAK2/STAT3 Pathway in High Grade B-cell Lymphoma. in The Journal of biological chemistry 2016 (PubMed)

  6. Human Polyclonal IL10RA Primary Antibody for ELISA, WB - ABIN1531662 : Josephson, Logsdon, Walter: Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site. in Immunity 2001 (PubMed)

  7. Human Polyclonal IL10RA Primary Antibody for FACS, IF - ABIN652714 : Jones, Logsdon, Josephson, Cook, Barry, Walter: Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

More Antibodies against IL10RA Interaction Partners

Human Interleukin 10 Receptor, alpha (IL10RA) interaction partners

  1. This study showed that lack of association with schizophrenia was detected for IL10 (show IL10 Antibodies) and IL10RA single polymorphisms and haplotypes.

  2. The IL-10RA rs9610 A allele was increased in rheumatoid arthritis (RA) patient group compared with control subjects. Interestingly, significant differences were detected both in the allele and genotype frequencies of rs9610 between anti-CCP (show CRYGD Antibodies) (anti-cyclic citrullinated peptide) positive patients and anti-CCP (show CRYGD Antibodies) negative patients. The findings suggest that IL-10RA rs9610 polymorphism might contribute to RA susceptibility.

  3. The quantitative methods used in this study have shown non-altered expression levels of different microglial markers (Iba-1 (show AIF1 Antibodies), Cd11b (show ITGAM Antibodies) and CD68 (show CD68 Antibodies)), together with increased expression of IL6 (show IL6 Antibodies), IL10RA, colony stimulating factor (show CSF2 Antibodies) 3 receptor and toll-like receptor 7 (show TLR7 Antibodies) in the thalamus in FFI, which explains the seemingly contradictory results of the previous studies.

  4. These results suggest that S138G loss-of-function polymorphism of the IL-10R1 may be important risk factor in increasing susceptibility to multiple sclerosis.

  5. Results reveal the structure of box1 from class II cytokine receptors IFNLR1 (show IL28RA Antibodies) and IL10RA bound to the FERM-SH2 domain of human JAK1 (show JAK1 Antibodies), identifying a consensus motif for JAK1 (show JAK1 Antibodies) interaction.

  6. Interleukin 10 (show IL10 Antibodies) and interleukin 10 receptor (show IL10RB Antibodies) expression was also enriched in interferon gamma (show IFNG Antibodies)-expressing activated CD8 (show CD8A Antibodies)(+) T cells. Treatment of anti-CD3 (show CD3 Antibodies)/CD28 (show CD28 Antibodies)-stimulated, purified CD8 (show CD8A Antibodies)(+) T cells with interleukin 10 (show IL10 Antibodies) alone could significantly enhance CD8 (show CD8A Antibodies)(+) T cell survival, an effect dependent on interleukin 10 receptor (show IL10RB Antibodies) expression

  7. a JAK2 (show JAK2 Antibodies) Inhibitor Suppresses a BCL6 (show BCL6 Antibodies)-dependent IL10RA/JAK2 (show JAK2 Antibodies)/STAT3 (show STAT3 Antibodies) Pathway in High Grade B-cell Lymphoma.

  8. results suggest that IL10 (show IL10 Antibodies)-mediated inhibition of autophagy is facilitated by the cross talk between STAT3 (show STAT3 Antibodies), AKT (show AKT1 Antibodies), and mTOR (show FRAP1 Antibodies); in other words, the IL10 (show IL10 Antibodies)-IL10R-STAT3 (show STAT3 Antibodies) and IL10 (show IL10 Antibodies)-AKT (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) pathways.

  9. genetic association study in cohort of infants/children: Data suggest perianal fistulas are exhibited in patients with very early-onset inflammatory bowel disease with IL10 (show IL10 Antibodies) receptor mutations (IL10RA/B); prognosis and response to treatment are poor.

  10. IL-10Ralpha expression is post-transcriptionally regulated by miR (show MLXIP Antibodies)-15a, miR (show MLXIP Antibodies)-185, and miR (show MLXIP Antibodies)-211 in melanoma

Mouse (Murine) Interleukin 10 Receptor, alpha (IL10RA) interaction partners

  1. TR1 (show TXNRD1 Antibodies) cell regulatory activity is dependent on IL-10 (show IL10 Antibodies) receptor signaling.

  2. loss of IL-10R signaling impaired the generation and function of anti-inflammatory intestinal and bone-marrow-derived macrophages and their ability to secrete IL-10 (show IL10 Antibodies).

  3. loss of IL-10 (show IL10 Antibodies) receptor expression impaired the critical conditioning of monocyte-derived macrophages and resulted in spontaneous development of severe colitis.

  4. Recent findings review how IL10 (show IL10 Antibodies)- and IL10R-dependent signaling modulates innate and adaptive immune responses in the murine intestine.

  5. Treatment of mice with rIFN-gamma was sufficient to drive expression of IL-10R1 in the colonic epithelium. Intestinal epithelial-specific IL-10R1-null mice were more susceptible to DSS (show PMP22 Antibodies) colitis associated with increased intestinal permeability.

  6. Inhibition of IL-10R signaling during bacillus Calmette-Guerin (BCG (show SLC11A1 Antibodies)) vaccination increases and balances IFN-gamma (show IFNG Antibodies) and IL-17A (show IL17A Antibodies) responses in favor of the host.

  7. IL-10R subunit-alpha signaling plays a key role in the development as well as B-cell help function of T (follicular helper) cells in vitro and in vivo.

  8. showed here that IL-17A (show IL17A Antibodies)-producing CD4 (show CD4 Antibodies)+ T cells expressed interleukin-10 receptor alpha (IL-10Ralpha) in vivo

  9. Data show that, in an IL-10 (show IL10 Antibodies)-dependent LPS (show TLR4 Antibodies) model of endotoxemia, dampening of the immune response requires expression of IL-10R1 in monocytes/macrophages and/or neutrophils but not in T cells nor B cells.

  10. reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor (show IL10RB Antibodies) antibody

IL10RA Antigen Profile

Antigen Summary

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Alternative names and synonyms associated with IL10RA

  • interleukin 10 receptor, alpha (IL10RA) antibody
  • interleukin 10 receptor, alpha (Il10ra) antibody
  • AW553859 antibody
  • CD210 antibody
  • CD210a antibody
  • CDw210 antibody
  • CDw210a antibody
  • HIL-10R antibody
  • IL-10R1 antibody
  • Il10r antibody
  • IL10R1 antibody
  • IL10RA antibody
  • mIL-10R antibody

Protein level used designations for IL10RA

interleukin 10 receptor 1 , interleukin-10 receptor subunit alpha , interleukin 10 receptor, alpha , interleukin-10 receptor subunit alpha-like , IL-10 receptor subunit alpha , IL-10R subunit 1 , IL-10R subunit alpha , IL-10RA , interleukin-10 receptor alpha chain , interleukin-10 receptor subunit 1 , IL-10R1

GENE ID SPECIES
419771 Gallus gallus
451580 Pan troglodytes
610823 Canis lupus familiaris
704383 Macaca mulatta
100396693 Callithrix jacchus
100436549 Pongo abelii
100469546 Ailuropoda melanoleuca
3587 Homo sapiens
16154 Mus musculus
100525654 Sus scrofa
513478 Bos taurus
117539 Rattus norvegicus
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