Browse our anti-GLI1 (GLI1) Antibodies

Full name:
anti-Zinc Finger Protein GLI1 Antibodies (GLI1)
On are 193 Zinc Finger Protein GLI1 (GLI1) Antibodies from 29 different suppliers available. Additionally we are shipping GLI1 Kits (10) and GLI1 Proteins (10) and many more products for this protein. A total of 220 GLI1 products are currently listed.
AV235269, Gli, Gli-1, gli1.1, Zfp-5, Zfp5
list all antibodies Gene Name GeneID UniProt
GLI1 2735 P08151
GLI1 140589  
GLI1 14632 P47806

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Top referenced anti-GLI1 Antibodies

  1. Human Polyclonal GLI1 Primary Antibody for ChIP, ELISA - ABIN153487 : Ghali, Wong, Green, Tidman, Quinn: Gli1 protein is expressed in basal cell carcinomas, outer root sheath keratinocytes and a subpopulation of mesenchymal cells in normal human skin. in The Journal of investigative dermatology 1999 (PubMed)
    Show all 28 references for 153487

  2. Cow (Bovine) Polyclonal GLI1 Primary Antibody for WB - ABIN2779593 : Rahnama, Shimokawa, Lauth, Finta, Kogerman, Teglund, Toftgård, Zaphiropoulos: Inhibition of GLI1 gene activation by Patched1. in The Biochemical journal 2006 (PubMed)
    Show all 9 references for 2779593

  3. Human Polyclonal GLI1 Primary Antibody for IF (p), IHC (p) - ABIN673374 : Zhang, Zhu, Zhou, Gao, Yuan, Han: Serotonin receptor 2C and insulin secretion. in PLoS ONE 2013 (PubMed)
    Show all 6 references for 673374

  4. Human Polyclonal GLI1 Primary Antibody for ICC, IF - ABIN4314249 : Jalili, Mertz, Romanov, Wagner, Kalthoff, Stuetz, Pathria, Gschaider, Stingl, Wagner: NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo. in PLoS ONE 2013 (PubMed)
    Show all 4 references for 4314249

  5. Human Polyclonal GLI1 Primary Antibody for WB - ABIN265275 : Wang, Chan, Rothnagel: Letters to the editor: identification of polymorphic variants of the GLI1 oncogene. in The Journal of investigative dermatology 2000 (PubMed)
    Show all 2 references for 265275

  6. Human Polyclonal GLI1 Primary Antibody for WB - ABIN4620372 : Kinzler, Ruppert, Bigner, Vogelstein: The GLI gene is a member of the Kruppel family of zinc finger proteins. in Nature 1988 (PubMed)

More Antibodies against GLI1 Interaction Partners

Human Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. The data described herein provide the first identification of a DYRK1A (show DYRK1A Antibodies)-mediated site of phosphorylation on GLI1 within its NLS (show ALDH1A2 Antibodies) and may serve as a valuable mechanism for further understanding Hh signaling modulation.

  2. Case Report: gastric pericytoma harboring the exceptionally rare translocation t(7;12) resulting in ACTB (show ACTB Antibodies)-GLI1 gene fusion.

  3. USP21 (show USP21 Antibodies) recruits and stabilises Gli1 at the centrosome.

  4. Gli1 expression was significantly correlated with T stage lymph node metastasis, and clinical stage of lung squamous cell carcinoma.

  5. Gli1 role in cell proliferation and differentiation

  6. Gli1 inhibitor GANT61 and SHH (show SHH Antibodies) siRNA synergistically enhanced cytotoxicity induced by itraconazole in MCF-7 cells.

  7. Hedgehog (show SHH Antibodies) pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.

  8. Our studies demonstrate an important role for smoothened (show SMO Antibodies) and glioma-associated oncogene homology-1 in gastric cancer and suggest inhibition of hedgehog (show SHH Antibodies) pathway as a novel and potent strategy to treat gastric cancer patients

  9. GANT61, which is a targeted inhibitor of Gli1 and Gli2 (show GLI2 Antibodies), decreased cell viability and promoted cell apoptosis. Thus, TGF-b1 induced EMT (show ITK Antibodies) in neuroblastoma (show ARHGEF16 Antibodies) cells to increase their migration. Specifically, EMT (show ITK Antibodies) induced by TGF-b1 in neuroblastoma (show ARHGEF16 Antibodies) cells did not depend on the Smad (show SMAD1 Antibodies) signaling pathway, and the transcription factor Gli participated in TGF-b1-induced EMT (show ITK Antibodies) independent of Smad (show SMAD1 Antibodies) signaling.

  10. Gli1 expression was detected in most ERM (show ETV5 Antibodies) specimens. Patients who had DR or OCT (show Plxna2 Antibodies) findings indicating chronic retinal insults showed higher Gli1 expression. Gli1 may have a role in the pathogenesis of ERM (show ETV5 Antibodies) after chronic retinal insults.

Cow (Bovine) Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. Data indicate that the expression levels of transcription factors Gli1 and Gli2 (show GLI2 Antibodies) in muscle were the lowest of the 13 tissues.

Xenopus laevis Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. Dzip1 (show DZIP1 Antibodies)-dependent stabilization of Spop (show SPOP Antibodies)/HIB is evolutionarily conserved and essential for proper regulation of Gli/Ci proteins in the Hh pathway.

  2. Zyxin (show ZYX Antibodies) inhibits Shh (show SHH Antibodies) signaling during the CNS patterning in Xenopus laevis through interaction with Gli1

Zebrafish Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. Mutation of hmgcs1 (show HMGCS1 Antibodies) had no effect on Shh (show SHH Antibodies) signaling at 2 and 3 days post fertilization (dpf), but did result in a decrease in the expression of gli1, a known Shh (show SHH Antibodies) target gene, at 4 dpf, after morphological deficits in craniofacial development and chondrocyte differentiation were observed in hmgcs1 (show HMGCS1 Antibodies) mutants.

  2. a new mechanism of Gli transcription factor activation and implicate ARHGAP36 (show ARHGAP36 Antibodies) dysregulation in the onset and/or progression of GLI-dependent cancers.

  3. We show that Kif7 (show KIF7 Antibodies) interacts with both Gli1 and Gli2a and suggest that it functions to sequester Gli proteins in the cytoplasm, in a manner analogous to the regulation of Ci by Cos2 (show KIF7 Antibodies) in Drosophila.

  4. Gli1 has a Hh-independent role in many motoneurons and V3 domain cells in embryos that lack Hh signalling, but removal of Gli1 activity does not affect more dorsal neurons.

  5. These results reveal divergent requirements for Gli1 and Gli2 (show GLI2 Antibodies) in mouse and zebrafish and indicate that zebrafish Gli1 is an activator of Hh-regulated genes, while zebrafish Gli2 (show GLI2 Antibodies) has minor roles as a repressor or activator of Hh targets.

  6. Gli1 regulates the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl (show SGPL1 Antibodies)) factor activity.

Mouse (Murine) Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. USP21 (show USP21 Antibodies) recruits and stabilises Gli1 at the centrosome.

  2. High Gli1 expression is associated with leukemia.

  3. Sufu (show SUFUH Antibodies) is upregulated in active Shh (show SHH Antibodies) responding tissues and accompanies Gli activators translocating into and Gli repressors out of the nucleus.

  4. Gli1 and Gli2 exhibited different functions in the regulation of p63 expression or proliferation of p63(+) cells in Kras-AR driven tumors.

  5. NANOG (show NANOG Antibodies) binds to GLI1 and GLI3 (show GLI3 Antibodies) proteins and represses Hedgehog (show SHH Antibodies)-mediated transcription.

  6. characterization of the contribution to remyelination of a subset of adult neural stem cells, identified by their expression of Gli1, a transcriptional effector of the sonic hedgehog (show SHH Antibodies) pathway

  7. the three GLI factors(GLI1, GLI2 (show GLI2 Antibodies), and GLI3 (show GLI3 Antibodies)) in mature hepatocytes form an interactive transcriptional network that is involved in the control of target genes associated with metabolic zonation as well as with lipid and drug metabolism

  8. Gli1, a known Ptch (show PTCH1 Antibodies) activator, preferentially bound the mutant Ptch (show PTCH1 Antibodies) locus in rhabdomyosarcoma.

  9. show that combined targeting of GLI and PI3K/AKT (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling can have a synergistic therapeutic effect in cells from a subgroup of chronic lymphocytic leukemia patients

  10. Beta-catenin (show CTNNB1 Antibodies) stabilization increases its physical interaction with Gli1.

GLI1 Antigen Profile

Antigen Summary

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with GLI1

  • GLI family zinc finger 1 (GLI1) antibody
  • GLI family zinc finger 1 (Gli1) antibody
  • GLI family zinc finger 1 (gli1) antibody
  • GLI-Kruppel family member 1 (gli1) antibody
  • GLI-Kruppel family member GLI1 (Gli1) antibody
  • AV235269 antibody
  • Gli antibody
  • Gli-1 antibody
  • gli1.1 antibody
  • Zfp-5 antibody
  • Zfp5 antibody

Protein level used designations for GLI1

glioma-associated oncogene 1 , glioma-associated oncogene homolog 1 (zinc finger protein) , oncogene GLI , zinc finger protein GLI1 , GLI-Kruppel family member GLI1 , GLI family zinc finger 1, gene 1 , zinc finger DNA binding protein Gli-1 , detour , dtr , glioma-associated oncogene homolog , zinc finger protein 5

2735 Homo sapiens
481126 Canis lupus familiaris
517588 Bos taurus
100033937 Equus caballus
140589 Rattus norvegicus
396045 Gallus gallus
398350 Xenopus laevis
352930 Danio rerio
14632 Mus musculus
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