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Browse our anti-GLI1 (GLI1) Antibodies

Full name:
anti-Zinc Finger Protein GLI1 Antibodies (GLI1)
On are 190 Zinc Finger Protein GLI1 (GLI1) Antibodies from 26 different suppliers available. Additionally we are shipping GLI1 Proteins (11) and GLI1 Kits (10) and many more products for this protein. A total of 218 GLI1 products are currently listed.
AV235269, Gli, Gli-1, gli1.1, Zfp-5, Zfp5
list all antibodies Gene Name GeneID UniProt
GLI1 2735 P08151
GLI1 140589  
GLI1 14632 P47806

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Most Popular Reactivities for anti-GLI1 (GLI1) Antibodies

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anti-Human GLI1 Antibodies:

anti-Rat (Rattus) GLI1 Antibodies:

anti-Mouse (Murine) GLI1 Antibodies:

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Top referenced anti-GLI1 Antibodies

  1. Human Polyclonal GLI1 Primary Antibody for ChIP, ELISA - ABIN153487 : Ghali, Wong, Green, Tidman, Quinn: Gli1 protein is expressed in basal cell carcinomas, outer root sheath keratinocytes and a subpopulation of mesenchymal cells in normal human skin. in The Journal of investigative dermatology 1999 (PubMed)
    Show all 25 references for ABIN153487

  2. Cow (Bovine) Polyclonal GLI1 Primary Antibody for WB - ABIN2779593 : Rahnama, Shimokawa, Lauth, Finta, Kogerman, Teglund, Toftgård, Zaphiropoulos: Inhibition of GLI1 gene activation by Patched1. in The Biochemical journal 2006 (PubMed)
    Show all 9 references for ABIN2779593

  3. Human Polyclonal GLI1 Primary Antibody for IF (p), IHC (p) - ABIN673374 : Zhang, Zhu, Zhou, Gao, Yuan, Han: Serotonin receptor 2C and insulin secretion. in PLoS ONE 2013 (PubMed)
    Show all 6 references for ABIN673374

  4. Human Polyclonal GLI1 Primary Antibody for ICC, IF - ABIN4314249 : Jalili, Mertz, Romanov, Wagner, Kalthoff, Stuetz, Pathria, Gschaider, Stingl, Wagner: NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo. in PLoS ONE 2013 (PubMed)
    Show all 4 references for ABIN4314249

  5. Human Polyclonal GLI1 Primary Antibody for WB - ABIN265275 : Wang, Chan, Rothnagel: Letters to the editor: identification of polymorphic variants of the GLI1 oncogene. in The Journal of investigative dermatology 2000 (PubMed)
    Show all 2 references for ABIN265275

  6. Human Polyclonal GLI1 Primary Antibody for WB - ABIN4620372 : Kinzler, Ruppert, Bigner, Vogelstein: The GLI gene is a member of the Kruppel family of zinc finger proteins. in Nature 1988 (PubMed)

More Antibodies against GLI1 Interaction Partners

Human Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. High expression of gli1 is associated with glioma chemoresistance.

  2. High Gli-1 expression is associated with pancreatic cancer.

  3. Our study is the first to demonstrate the associations of high nuclear Gli1 expression with resistance to trastuzumab-based NAT (show BRD2 Antibodies) and subsequent worse prognosis in HER2 (show ERBB2 Antibodies)-positive disease. These findings suggest that the nuclear Gli1 protein may be a novel target of NAT (show BRD2 Antibodies) for HER2 (show ERBB2 Antibodies)-positive breast cancer.

  4. GLI is an oncogenic transcription factor in the SHH (show SHH Antibodies) pathway, and targeting GLI with GANT61 results in favourable antitumour activity and targeted therapy.

  5. PRMT1 (show PRMT1 Antibodies) promoted the methylation of Gli1.

  6. Genetic variant in GLI-1 gene is associated with gallbladder cancer.

  7. Gli1 expression was positively associated with distant metastasis, increased microvessel density, and expression of cell cycle regulators such as p21 (show CDKN1A Antibodies), cyclin D1 (show CCND1 Antibodies), cyclin E1 (show CCNE1 Antibodies), and NF-kappaB (show NFKB1 Antibodies) in esophageal squamous cell carcinoma.

  8. Low GLI1 expression is associated with breast cancer.

  9. Knock down of Gli1 by siRNA interference reduced the viability of glioma cells as well as suppressed cell metastasis.

  10. High GLI expression is associated with pancreatic and skin cancers.

Cow (Bovine) Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. Data indicate that the expression levels of transcription factors Gli1 and Gli2 (show GLI2 Antibodies) in muscle were the lowest of the 13 tissues.

Xenopus laevis Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. Dzip1 (show DZIP1 Antibodies)-dependent stabilization of Spop (show SPOP Antibodies)/HIB is evolutionarily conserved and essential for proper regulation of Gli/Ci proteins in the Hh pathway.

  2. Zyxin (show ZYX Antibodies) inhibits Shh (show SHH Antibodies) signaling during the CNS patterning in Xenopus laevis through interaction with Gli1

Zebrafish Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. a new mechanism of Gli transcription factor activation and implicate ARHGAP36 (show ARHGAP36 Antibodies) dysregulation in the onset and/or progression of GLI-dependent cancers.

  2. We show that Kif7 (show KIF7 Antibodies) interacts with both Gli1 and Gli2a and suggest that it functions to sequester Gli proteins in the cytoplasm, in a manner analogous to the regulation of Ci by Cos2 (show KIF7 Antibodies) in Drosophila.

  3. Gli1 has a Hh-independent role in many motoneurons and V3 domain cells in embryos that lack Hh signalling, but removal of Gli1 activity does not affect more dorsal neurons.

  4. These results reveal divergent requirements for Gli1 and Gli2 (show GLI2 Antibodies) in mouse and zebrafish and indicate that zebrafish Gli1 is an activator of Hh-regulated genes, while zebrafish Gli2 (show GLI2 Antibodies) has minor roles as a repressor or activator of Hh targets.

  5. Gli1 regulates the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl (show SGPL1 Antibodies)) factor activity.

Mouse (Murine) Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. NANOG (show NANOG Antibodies) binds to GLI1 and GLI3 (show GLI3 Antibodies) proteins and represses Hedgehog (show SHH Antibodies)-mediated transcription.

  2. characterization of the contribution to remyelination of a subset of adult neural stem cells, identified by their expression of Gli1, a transcriptional effector of the sonic hedgehog (show SHH Antibodies) pathway

  3. the three GLI factors(GLI1, GLI2 (show GLI2 Antibodies), and GLI3 (show GLI3 Antibodies)) in mature hepatocytes form an interactive transcriptional network that is involved in the control of target genes associated with metabolic zonation as well as with lipid and drug metabolism

  4. Gli1, a known Ptch (show PTCH1 Antibodies) activator, preferentially bound the mutant Ptch (show PTCH1 Antibodies) locus in rhabdomyosarcoma.

  5. show that combined targeting of GLI and PI3K/AKT (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling can have a synergistic therapeutic effect in cells from a subgroup of chronic lymphocytic leukemia patients

  6. Beta-catenin (show CTNNB1 Antibodies) stabilization increases its physical interaction with Gli1.

  7. These findings implicate perivascular Gli1(+) mesenchymal stem cells-like cells as a major cellular origin of organ fibrosis.

  8. Cortical activation of Gli1 protects mice from induction of hepatic encephalopathy. TGFbeta1 (show TGFB1 Antibodies) suppresses Gli1 in neurons via SMAD3 (show SMAD3 Antibodies) and promotes the neurologic decline.

  9. Ptc1 (show PTCH1 Antibodies)-Gli1 signaling deregulation resulting in abnormal loss of glial precursor cells may contribute to a cognition decline in Alzheimer's disease brains.

  10. Gli1+ cells within the suture mesenchyme are an indispensable mesenchymal stem cell population supporting craniofacial bone turnover and injury healing.

GLI1 Antigen Profile

Antigen Summary

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with GLI1

  • GLI family zinc finger 1 (GLI1) antibody
  • GLI family zinc finger 1 (Gli1) antibody
  • GLI family zinc finger 1 (gli1) antibody
  • GLI-Kruppel family member 1 (gli1) antibody
  • GLI-Kruppel family member GLI1 (Gli1) antibody
  • AV235269 antibody
  • Gli antibody
  • Gli-1 antibody
  • gli1.1 antibody
  • Zfp-5 antibody
  • Zfp5 antibody

Protein level used designations for GLI1

glioma-associated oncogene 1 , glioma-associated oncogene homolog 1 (zinc finger protein) , oncogene GLI , zinc finger protein GLI1 , GLI-Kruppel family member GLI1 , GLI family zinc finger 1, gene 1 , zinc finger DNA binding protein Gli-1 , detour , dtr , glioma-associated oncogene homolog , zinc finger protein 5

2735 Homo sapiens
481126 Canis lupus familiaris
517588 Bos taurus
100033937 Equus caballus
140589 Rattus norvegicus
396045 Gallus gallus
398350 Xenopus laevis
352930 Danio rerio
14632 Mus musculus
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