Browse our GLI1 (GLI1) ELISA Kits

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Zinc Finger Protein GLI1 ELISA Kits (GLI1)
On www.antibodies-online.com are 10 Zinc Finger Protein GLI1 (GLI1) ELISA Kits from 6 different suppliers available. Additionally we are shipping GLI1 Antibodies (193) and GLI1 Proteins (10) and many more products for this protein. A total of 220 GLI1 products are currently listed.
Synonyms:
AV235269, Gli, Gli-1, gli1.1, Zfp-5, Zfp5
list all ELISA KIts Gene Name GeneID UniProt
GLI1 2735 P08151
Rat GLI1 GLI1 140589  
GLI1 14632 P47806

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Human Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. Case Report: gastric pericytoma harboring the exceptionally rare translocation t(7;12) resulting in ACTB (show ACTB ELISA Kits)-GLI1 gene fusion.

  2. USP21 (show USP21 ELISA Kits) recruits and stabilises Gli1 at the centrosome.

  3. Gli1 expression was significantly correlated with T stage lymph node metastasis, and clinical stage of lung squamous cell carcinoma.

  4. Gli1 role in cell proliferation and differentiation

  5. Gli1 inhibitor GANT61 and SHH (show SHH ELISA Kits) siRNA synergistically enhanced cytotoxicity induced by itraconazole in MCF-7 cells.

  6. Hedgehog (show SHH ELISA Kits) pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.

  7. Our studies demonstrate an important role for smoothened and glioma-associated oncogene homology-1 in gastric cancer and suggest inhibition of hedgehog (show SHH ELISA Kits) pathway as a novel and potent strategy to treat gastric cancer patients

  8. GANT61, which is a targeted inhibitor of Gli1 and Gli2 (show GLI2 ELISA Kits), decreased cell viability and promoted cell apoptosis. Thus, TGF-b1 induced EMT (show ITK ELISA Kits) in neuroblastoma (show ARHGEF16 ELISA Kits) cells to increase their migration. Specifically, EMT (show ITK ELISA Kits) induced by TGF-b1 in neuroblastoma (show ARHGEF16 ELISA Kits) cells did not depend on the Smad (show SMAD1 ELISA Kits) signaling pathway, and the transcription factor Gli participated in TGF-b1-induced EMT (show ITK ELISA Kits) independent of Smad (show SMAD1 ELISA Kits) signaling.

  9. Gli1 expression was detected in most ERM specimens. Patients who had DR or OCT findings indicating chronic retinal insults showed higher Gli1 expression. Gli1 may have a role in the pathogenesis of ERM after chronic retinal insults.

  10. Overexpression of GLI1 through a recurrent MALAT1-GLI1 translocation or GLI1 up-regulation delineates a pathogenically distinct subgroup of plexiform fibromyxomas with activation of the Sonic Hedgehog (show SHH ELISA Kits) signalling pathway.

Cow (Bovine) Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. Data indicate that the expression levels of transcription factors Gli1 and Gli2 (show GLI2 ELISA Kits) in muscle were the lowest of the 13 tissues.

Xenopus laevis Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. Dzip1-dependent stabilization of Spop (show SPOP ELISA Kits)/HIB is evolutionarily conserved and essential for proper regulation of Gli/Ci proteins in the Hh pathway.

  2. Zyxin (show ZYX ELISA Kits) inhibits Shh (show SHH ELISA Kits) signaling during the CNS patterning in Xenopus laevis through interaction with Gli1

Zebrafish Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. a new mechanism of Gli transcription factor activation and implicate ARHGAP36 (show ARHGAP36 ELISA Kits) dysregulation in the onset and/or progression of GLI-dependent cancers.

  2. We show that Kif7 (show KIF7 ELISA Kits) interacts with both Gli1 and Gli2a and suggest that it functions to sequester Gli proteins in the cytoplasm, in a manner analogous to the regulation of Ci by Cos2 (show KIF7 ELISA Kits) in Drosophila.

  3. Gli1 has a Hh-independent role in many motoneurons and V3 domain cells in embryos that lack Hh signalling, but removal of Gli1 activity does not affect more dorsal neurons.

  4. These results reveal divergent requirements for Gli1 and Gli2 (show GLI2 ELISA Kits) in mouse and zebrafish and indicate that zebrafish Gli1 is an activator of Hh-regulated genes, while zebrafish Gli2 (show GLI2 ELISA Kits) has minor roles as a repressor or activator of Hh targets.

  5. Gli1 regulates the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl (show SGPL1 ELISA Kits)) factor activity.

Mouse (Murine) Zinc Finger Protein GLI1 (GLI1) interaction partners

  1. USP21 (show USP21 ELISA Kits) recruits and stabilises Gli1 at the centrosome.

  2. High Gli1 expression is associated with leukemia.

  3. Sufu (show SUFUH ELISA Kits) is upregulated in active Shh (show SHH ELISA Kits) responding tissues and accompanies Gli activators translocating into and Gli repressors out of the nucleus.

  4. Gli1 and Gli2 exhibited different functions in the regulation of p63 expression or proliferation of p63(+) cells in Kras-AR driven tumors.

  5. NANOG (show NANOG ELISA Kits) binds to GLI1 and GLI3 (show GLI3 ELISA Kits) proteins and represses Hedgehog (show SHH ELISA Kits)-mediated transcription.

  6. characterization of the contribution to remyelination of a subset of adult neural stem cells, identified by their expression of Gli1, a transcriptional effector of the sonic hedgehog (show SHH ELISA Kits) pathway

  7. the three GLI factors(GLI1, GLI2 (show GLI2 ELISA Kits), and GLI3 (show GLI3 ELISA Kits)) in mature hepatocytes form an interactive transcriptional network that is involved in the control of target genes associated with metabolic zonation as well as with lipid and drug metabolism

  8. Gli1, a known Ptch (show PTCH1 ELISA Kits) activator, preferentially bound the mutant Ptch (show PTCH1 ELISA Kits) locus in rhabdomyosarcoma.

  9. show that combined targeting of GLI and PI3K/AKT (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) signaling can have a synergistic therapeutic effect in cells from a subgroup of chronic lymphocytic leukemia patients

  10. Beta-catenin (show CTNNB1 ELISA Kits) stabilization increases its physical interaction with Gli1.

GLI1 Antigen Profile

Antigen Summary

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with GLI1

  • GLI family zinc finger 1 (GLI1) Elisa Kit
  • GLI family zinc finger 1 (Gli1) Elisa Kit
  • GLI family zinc finger 1 (gli1) Elisa Kit
  • GLI-Kruppel family member 1 (gli1) Elisa Kit
  • GLI-Kruppel family member GLI1 (Gli1) Elisa Kit
  • AV235269 Elisa Kit
  • Gli Elisa Kit
  • Gli-1 Elisa Kit
  • gli1.1 Elisa Kit
  • Zfp-5 Elisa Kit
  • Zfp5 Elisa Kit

Protein level used designations for GLI1

glioma-associated oncogene 1 , glioma-associated oncogene homolog 1 (zinc finger protein) , oncogene GLI , zinc finger protein GLI1 , GLI-Kruppel family member GLI1 , GLI family zinc finger 1, gene 1 , zinc finger DNA binding protein Gli-1 , detour , dtr , glioma-associated oncogene homolog , zinc finger protein 5

GENE ID SPECIES
2735 Homo sapiens
481126 Canis lupus familiaris
517588 Bos taurus
100033937 Equus caballus
140589 Rattus norvegicus
396045 Gallus gallus
398350 Xenopus laevis
352930 Danio rerio
14632 Mus musculus
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