Browse our GLI2 (GLI2) ELISA Kits

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GLI Family Zinc Finger 2 ELISA Kits (GLI2)
On www.antibodies-online.com are 5 GLI Family Zinc Finger 2 (GLI2) ELISA Kits from 3 different suppliers available. Additionally we are shipping GLI2 Antibodies (90) and and many more products for this protein. A total of 99 GLI2 products are currently listed.
Synonyms:
AW546128, GLI2/GLI4, GLI3, HPE9, THP1, THP2
list all ELISA KIts Gene Name GeneID UniProt
GLI2 2736 P10070
Rat GLI2 GLI2 304729  
GLI2 14633 Q0VGT2

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GLI2 (GLI2) ELISA Kits by Reactivity

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More ELISA Kits for GLI2 Interaction Partners

Human GLI Family Zinc Finger 2 (GLI2) interaction partners

  1. bioinformatics analysis and luciferase reporter assay predicted the direct binding to miR (show MLXIP ELISA Kits)-125b-5p, which has been reported to function as a tumor suppressor in osteosarcoma. Furthermore, functional experiments validated that cir (show KCNJ5 ELISA Kits)-GLI2 exerted the tumor-promoting effects on osteosarcoma cells via negatively targeting miR (show MLXIP ELISA Kits)-125b-5p.

  2. GANT61, which is a targeted inhibitor of Gli1 (show GLI1 ELISA Kits) and Gli2, decreased cell viability and promoted cell apoptosis. Thus, TGF-b1 induced EMT (show ITK ELISA Kits) in neuroblastoma (show ARHGEF16 ELISA Kits) cells to increase their migration. Specifically, EMT (show ITK ELISA Kits) induced by TGF-b1 in neuroblastoma (show ARHGEF16 ELISA Kits) cells did not depend on the Smad (show SMAD1 ELISA Kits) signaling pathway, and the transcription factor Gli (show GLI1 ELISA Kits) participated in TGF-b1-induced EMT (show ITK ELISA Kits) independent of Smad (show SMAD1 ELISA Kits) signaling.

  3. These results demonstrate that miR (show MLXIP ELISA Kits)-124 is an important downstream target gene of Hh signaling, and the Gli2/miR (show MLXIP ELISA Kits)-124/AURKA (show AURKA ELISA Kits) axis is essential for the proliferation and growth of human glioma cells.

  4. in trophoblasts, GLI2 not only directly bound to the promoter region of gene hsd11b2 (show HSD11B2 ELISA Kits) to transactivate hsd11b2 (show HSD11B2 ELISA Kits) but also formed a heterodimer with RNA polymerase II, resulting in up-regulation of hsd11b2 (show HSD11B2 ELISA Kits) gene transcription

  5. GLI2 was identified as a crucial downstream mediator of the pro-fibrotic effects of TGF-beta (show TGFB1 ELISA Kits).

  6. Gli1 and Gli2 exhibited different functions in the regulation of p63 expression or proliferation of p63(+) cells in Kras-AR driven tumors.

  7. this study shows that Gli2 expression was more often positive in advanced non-small-cell lung carcinoma patients refractory to platinum-based chemotherapy

  8. Beclin-1 (show BECN1 ELISA Kits) acts as a tumor suppressor by regulating the hedgehog (show SHH ELISA Kits) (HH) signaling pathway through Gli2 expression in gastric adenocarcinoma.

  9. Overexpression of GLI2 is associated with osteosarcoma progression.

  10. MALAT1 promotes gastric cancer proliferation and progression. MALAT1 is a direct target of miR (show MLXIP ELISA Kits)-202 and knockdown of MALAT1 significantly decreases the expression of Gli2 by negatively regulating miR (show MLXIP ELISA Kits)-202.

Cow (Bovine) GLI Family Zinc Finger 2 (GLI2) interaction partners

  1. Data indicate that the expression levels of transcription factors Gli1 (show GLI1 ELISA Kits) and Gli2 in muscle were the lowest of the 13 tissues.

Pig (Porcine) GLI Family Zinc Finger 2 (GLI2) interaction partners

  1. The 12 SNPs of GLI2 encompassing exon 4 to exon 8 showed strong association with in the anorectal atresia in pigs.

Mouse (Murine) GLI Family Zinc Finger 2 (GLI2) interaction partners

  1. Sufu (show SUFUH ELISA Kits) is upregulated in active Shh (show SHH ELISA Kits) responding tissues and accompanies Gli (show GLI1 ELISA Kits) activators translocating into and Gli (show GLI1 ELISA Kits) repressors out of the nucleus.

  2. Gli2+/-;Gli3Delta699/+ mice can serve as a genetic mouse model for common DSD (show FADS1 ELISA Kits).

  3. Despite increased production of full-length GLI2 and GLI3 (show GLI3 ELISA Kits) isoforms, previously identified GLI (show GLI1 ELISA Kits) targets important for mandibular and glossal development (Foxf1 (show FOXF1 ELISA Kits), Foxf2 (show FOXF2 ELISA Kits), Foxd1 (show FOXD1 ELISA Kits) and Foxd2 (show FOXD2 ELISA Kits)) were transcriptionally downregulated in Kif3a (show KIF3A ELISA Kits)(f/f);Wnt1 (show WNT1 ELISA Kits)-Cre embryos.

  4. Gli1 and Gli2 exhibited different functions in the regulation of p63 expression or proliferation of p63(+) cells in Kras-AR driven tumors.

  5. the GLI2 protein level could serve as a feasible marker of ligand-dependent hedgehog (show SHH ELISA Kits) activation in pancreatic neoplasms.

  6. Study suggested that loss of Gli2 mRNA mediated the anterior-restricted defect in conditional Dicer (show DICER1 ELISA Kits) knockdown mice and showed that miR (show MLXIP ELISA Kits)-106b positively regulated Gli2 mRNA expression

  7. Sufu (show SUFUH ELISA Kits) deletion early in embryogenesis resulted in unstable Gli2 and Gli3 (show GLI3 ELISA Kits) activity, leading to the ectopic activation of Shh (show SHH ELISA Kits) signaling.

  8. the three GLI (show GLI1 ELISA Kits) factors(GLI1 (show GLI1 ELISA Kits), GLI2, and GLI3 (show GLI3 ELISA Kits)) in mature hepatocytes form an interactive transcriptional network that is involved in the control of target genes associated with metabolic zonation as well as with lipid and drug metabolism

  9. Gli2 protein expression is downregulated during neural tube patterning, regulating Shh (show SHH ELISA Kits) signaling. Shh (show SHH ELISA Kits)-induced upregulation of Gli2 transcription prevents Gli (show GLI1 ELISA Kits) activity levels from adapting in a different cell type.

  10. GLI2 binds to the IL-6Ralpha (show IL6R ELISA Kits) promoter and regulates its activity as well as the expression of this receptor.

GLI2 Antigen Profile

Antigen Summary

This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Alternative names and synonyms associated with GLI2

  • GLI-Kruppel family member GLI2 (LOC100359289) Elisa Kit
  • GLI family zinc finger 2 (GLI2) Elisa Kit
  • GLI family zinc finger 2 (Gli2) Elisa Kit
  • GLI-Kruppel family member GLI2 (Gli2) Elisa Kit
  • AW546128 Elisa Kit
  • GLI2/GLI4 Elisa Kit
  • GLI3 Elisa Kit
  • HPE9 Elisa Kit
  • THP1 Elisa Kit
  • THP2 Elisa Kit

Protein level used designations for GLI2

GLI-Kruppel family member GLI2 , glioma-associated oncogene family zinc finger 2 , oncogene GLI2 , tax helper protein 1 , tax helper protein 2 , tax-responsive element-2 holding protein , tax-responsive element-25-bp sequence binding protein , zinc finger protein GLI2 , Zn finger transcription factor , zinc finger protein GLI3 , Tax helper protein

GENE ID SPECIES
100359289 Oryctolagus cuniculus
2736 Homo sapiens
304729 Rattus norvegicus
459582 Pan troglodytes
510255 Bos taurus
395956 Gallus gallus
100682984 Canis lupus familiaris
100520334 Sus scrofa
14633 Mus musculus
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