Browse our GNRH1 Proteins (GNRH1)

Full name:
Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) Proteins (GNRH1)
On are 24 Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) Proteins from 5 different suppliers available. Additionally we are shipping GNRH1 Antibodies (107) and GNRH1 Kits (58) and many more products for this protein. A total of 207 GNRH1 products are currently listed.
CGNRH-I, GnRH, GnRH-I, Gnrh2, Gnrha, GRH, HH12, hpg, Lhrh, Lhrh1, LNRH, Rgnrhg1
list all proteins Gene Name GeneID UniProt
GNRH1 14714 P13562
GNRH1 2796 P01148
GNRH1 25194 P07490

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GNRH1 Proteins (GNRH1) by Origin

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Mouse (Murine) Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) interaction partners

  1. GnRH-E1 RNA is an inducer of Gnrh1 gene expression that may play an important role in the development and maturation of GnRH neurons

  2. tet2 activity in GnRH neurons has influence over the neuroendocrine control of male reproductive function

  3. Neurons in the hypothalamus produce Kiss1 and can synchronize their activity and activate GnRH neurons thus coordinating reproduction and fertility.

  4. GnRH stimulated the secretion of the VGF (show VGF Proteins)-derived peptide NERP1 (show VGF Proteins). NERP1 (show VGF Proteins) caused a concentration-dependent decrease in Fshb (show FSHB Proteins) gene induction.

  5. DHA and palmitate increase Gnrh enhancer-derived RNA levels.

  6. findings suggest that GnRH is necessary for constitutive ANXA5 (show ANXA5 Proteins) expression in the pituitary gland, not only in gonadotropes but also in other pituitary gland cell types

  7. In this study, we investigate the mechanism by which VAX1 controls fertility finding that VAX1 is required for maintenance of Gnrh1 gene expression and deletion of Vax1 from GnRH neurons leads to complete infertility.

  8. RALDH and RA might not be directly involved in the reduction of GnRH expression induced by TSA, however these substances could be a novel regulator of GnRH.

  9. The profound effect of Sirt1 (show SIRT1 Proteins) on the hormonal status of Sirt1 (show SIRT1 Proteins)(-/-) mice, mediated via defective GnRH neuronal migration, links energy metabolism directly to the hypogonadal state.

  10. neural circuits between kisspeptin and GnRH neurons in the male mouse arcuate nucleus of the hypothalamus established before birth

Guinea Pig Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) interaction partners

  1. Guinea pig GnRH is predominantly present in the brain and has a lower in vivo luteinizaing hormone (LH)-releasing activity than Gnrh of the rat.

Human Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) interaction partners

  1. High expression of LHRH is associated with ovarian cancer.

  2. Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb (show FSHB Proteins) gene sensitivity to gonadotropin-releasing hormone pulse frequency

  3. GNRH (and GNRHR (show GNRHR Proteins)) are expressed in trophoblast cell populations and fallopian tube epithelium at tubal ectopic pregnancy sites.

  4. High LHRH expression is associated with sarcomas of bone and soft tissue.

  5. GnRH regulates trophoblast invasion via RUNX2 (show RUNX2 Proteins)-mediated MMP2 (show MMP2 Proteins)/MMP9 (show MMP9 Proteins) expression.

  6. our results showed that GnRH participates in the self-renewal capacity and stemness maintenance of LCSLCs by upregulating the JNK signaling pathway, and GnRH may be useful as an alternative lung cancer stem-like cells therapy.

  7. Melatonin affects the secretion of GnRH, LH and testosterone, improves sperm quality thereby regulating the testicular development and male reproduction. (Review)

  8. Data suggest differences in regulation of expression of PEDF (show SERPINF1 Proteins) (up-regulation) vs. VEGF (show VEGFA Proteins) (down-regulation) in granulosa cells explain reduced risk of ovarian hyperstimulation syndrome due to ovulation induction using GnRH/GNRHR (show GNRHR Proteins) agonists rather than hCG (show CGA Proteins).

  9. No abnormalities were found in the patient group for the PROKR2 (show PROKR2 Proteins) and GNRH1genes. In addition, no genomic rearrangements were identified in the healthy control individuals for the described genes

  10. Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in humans and mice.

Rhesus Monkey Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) interaction partners

  1. findings report the changes in inhibin-alpha subunit gene expression in the corpus luteum is regulated by LH; results suggest a possible multiple crosstalk of Wnt, cAMP, and SF-1 in the regulation of luteal inhibin secretion

  2. Posterior hypothalamic lesion animals had elevated LHRH levels and higher evening glutamate (show GRIN2C Proteins) levels after lesions, whereas LHRH changes did not occur in sham/controls until later.

  3. Estradiol(E2) induces a rapid excitatory effect on primate LHRH neurons, and this rapid action of E2 appears to be mediated, in part, through GPR30.

GNRH1 Protein Profile

Protein Summary

The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene.

Alternative names and synonyms associated with GNRH1

  • gonadotropin releasing hormone 1 (Gnrh1)
  • gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) (GNRH1)
  • gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) (Gnrh1)
  • CGNRH-I protein
  • GnRH protein
  • GnRH-I protein
  • Gnrh2 protein
  • Gnrha protein
  • GRH protein
  • HH12 protein
  • hpg protein
  • Lhrh protein
  • Lhrh1 protein
  • LNRH protein
  • Rgnrhg1 protein

Protein level used designations for GNRH1

gonadotropin releasing hormone 2 , hypogonadal , luteinizing hormone-releasing hormone I , progonadoliberin I , progonadoliberin-1 , luteinizing hormone-releasing hormone , GnRH-associated peptide 1 , gonadotropin-releasing hormone 1 (leutinizing-releasing hormone) , luliberin I , prolactin release-inhibiting factor , gonadotropin releasing hormone 1 , gonadotropin-releasing hormone associated peptide , chicken gonadotrophin releasing hormone-I , gonadotrophin-releasing hormone I , Progonadoliberin-1 , progonadoliberin-1 preproprotein , Progonadoliberin I

14714 Mus musculus
100135531 Cavia porcellus
2796 Homo sapiens
25194 Rattus norvegicus
397516 Sus scrofa
770134 Gallus gallus
443529 Ovis aries
613033 Macaca mulatta
101111690 Ovis aries
101832723 Mesocricetus auratus
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