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Browse our HNF1 Homeobox A Proteins (HNF1A)

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HNF1 Homeobox A Proteins (HNF1A)
On are 5 HNF1 Homeobox A (HNF1A) Proteins from 4 different suppliers available. Additionally we are shipping HNF1 Homeobox A Antibodies (94) and HNF1 Homeobox A Kits (35) and many more products for this protein. A total of 142 HNF1 Homeobox A products are currently listed.
AI323641, HNF-1, HNF-1-alpha, HNF-1a, HNF-1alpha, HNF1, HNF1-alpha, HNF1A, Hnf1alpha, HNF1[a], IDDM20, LF-B1, Lfb1, MODY3, Tcf-1, tcf1
list all proteins Gene Name GeneID UniProt
HNF1A 6927 P20823
HNF1A 21405 P22361
HNF1A 24817 P15257

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HNF1 Homeobox A Proteins (HNF1A) by Origin

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More Proteins for HNF1 Homeobox A Interaction Partners

Human HNF1 Homeobox A (HNF1A) interaction partners

  1. 11 variants that reduced HNF-1A transcriptional activity to <60% of normal (wild-type) activity was strongly associated with diabetes in the general population.

  2. The G allele of rs7953249 of HNF1A showed nominal association with small vessel disease subtype of ischemic stroke though not survived bonferroni correction for multiple comparisons.

  3. Mutation of HNF1A is associated with type 1B diabetes.

  4. TCF1 expression is regulated by SOX18 (show SOX18 Proteins) in prostate cancer.

  5. HNF1A mutations are associated with Maturity-Onset Diabetes of the Young.

  6. HNF1A gene polymorphisms (rs2259816 and rs7310409) showed statistically significant association with risk of coronary artery disease in Iranian patients.

  7. We show that SNPs in HNF1A (rs1169288 and rs2464196) are more frequent among dead opioid addicts than living opioid addicts.

  8. High TCF-1 expression is associated with dedifferentiated chondrosarcoma.

  9. co-expression of HNF4alpha (show HNF4A Proteins) and HNF1alpha is effective for cellular lipid accumulation, while additional factors are probably required for lipoprotein formation and secretion

  10. HNF1alpha plays a key role in the constitutive expression of megalin (show LRP2 Proteins) and cubilin (show CUBN Proteins), hence regulating endocytosis in the proximal tubule of the kidney.

Mouse (Murine) HNF1 Homeobox A (HNF1A) interaction partners

  1. Data show that the Wnt-effector hepatocyte nuclear factor 1-alpha (Tcf1) is recruited to and triggers transcription of the Ink4/Arf tumor suppressor locus, such as as p15Ink4b, p16Ink4a and p19Arf.

  2. this study shows that distinct, asynchronous and stage-specific transcription factors (TCF-1, GATA-3 and Runx1) activate Bcl11b for T cell commitment

  3. this study shows that the transcription factors Tcf1 and Lef1 (show LEF1 Proteins) suppress CD4 (show CD4 Proteins)+ T lineage genes in CD8 (show CD8A Proteins)+ T cells through intrinsic histone deacetylase (show HDAC1 Proteins) activity

  4. Results show that Tcf1 binding to Zfp703 (show ZNF703 Proteins) inhibits beta-catenin (show CTNNB1 Proteins)/Tcf1 complex formation.

  5. this study shows that Tcf1 short isoforms are adequate in supporting developing thymocytes to traverse through maturation steps and in regulating the expression of most Tcf1 target genes

  6. HNF1alpha plays a key role in the constitutive expression of megalin (show LRP2 Proteins) and cubilin (show CUBN Proteins), hence regulating endocytosis in the proximal tubule of the kidney.

  7. leukemic stem cells are therefore more sensitive to loss of Tcf1 and Lef1 (show LEF1 Proteins) than Hematopoietic Stem Cells in their self-renewal capacity.

  8. Sp5 (show SP5 Proteins)/8 bind directly to GC boxes in Wnt (show WNT2 Proteins) target gene enhancers and to adjacent, or distally positioned, chromatin-bound T-cell factor (Tcf) 1/lymphoid enhancer factor (Lef) 1 (show LEF1 Proteins) to facilitate recruitment of beta-catenin (show CTNNB1 Proteins) to target gene enhancers.

  9. TCF1 is required for the T follicular helper cell response to viral infection functioning through negative feedback loops with IL-2 (show IL2 Proteins) and Blimp1 (show PRDM1 Proteins).

  10. Our data demonstrate that HNF1A is an important cell-intrinsic transcription factor in adult B lymphopoiesis

Pig (Porcine) HNF1 Homeobox A (HNF1A) interaction partners

  1. pigs harboring the dominant-negative mutant human MODY3 gene showed reproducible and distinct glomerular nodules.

HNF1 Homeobox A (HNF1A) Protein Profile

Protein Summary

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.

Alternative names and synonyms associated with HNF1 Homeobox A (HNF1A)

  • HNF1 homeobox A (HNF1A)
  • HNF1 homeobox A (Hnf1a)
  • transcription factor 1, hepatic (hnf1)
  • AI323641 protein
  • HNF-1 protein
  • HNF-1-alpha protein
  • HNF-1a protein
  • HNF-1alpha protein
  • HNF1 protein
  • HNF1-alpha protein
  • HNF1A protein
  • Hnf1alpha protein
  • HNF1[a] protein
  • IDDM20 protein
  • LF-B1 protein
  • Lfb1 protein
  • MODY3 protein
  • Tcf-1 protein
  • tcf1 protein

Protein level used designations for HNF1 Homeobox A Proteins (HNF1A)

HNF1 homeobox A , HNF-1-alpha , albumin proximal factor , hepatic nuclear factor 1 , hepatocyte nuclear factor 1-alpha , interferon production regulator factor , liver-specific transcription factor LF-B1 , transcription factor 1, hepatic , hepatic nuclear factor (HNF1) , transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor , HNF-1A , hepatocyte nuclear factor 1 , transcription factor 1 , LF-B1 hepatic nuclear factor (HNF1): albumin proximal factor also TCF1 , LF-B1, hepatic nuclear factor (HNF1): albumin proximal factor, also TCF1 , TCF-1 , Transcription factor 1 hepatic , Transcription factor 1, hepatic , hepatic nuclear factor-1-alpha , hepatocyte nuclear factor 1 alpha , sHNF1

100018223 Monodelphis domestica
6927 Homo sapiens
416967 Gallus gallus
21405 Mus musculus
486303 Canis lupus familiaris
24817 Rattus norvegicus
574067 Sus scrofa
100714798 Cavia porcellus
503578 Bos taurus
100136586 Salmo salar
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