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Browse our MYO5A Proteins (MYO5A)

Full name:
Myosin VA Proteins (MYO5A)
On are 3 Myosin VA (MYO5A) Proteins from 3 different suppliers available. Additionally we are shipping MYO5A Antibodies (26) and MYO5A Kits (4) and many more products for this protein. A total of 39 MYO5A products are currently listed.
9630007J19Rik, AI413174, AI661011, d, d-120J, Dbv, DILUTE, Dop, flail, flr, GS1, MGC53270, MVa, MYH12, MYO5, MYO5A, MYOA, MyoVA, myoxin), MYR12, non-muscle, Sev-1, si:dkey-266j9.1
list all proteins Gene Name GeneID UniProt
Rat MYO5A MYO5A 25017 Q9QYF3
Mouse MYO5A MYO5A 17918 Q99104
MYO5A 4644 Q9Y4I1

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MYO5A Proteins (MYO5A) by Origin

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More Proteins for MYO5A Interaction Partners

Xenopus laevis Myosin VA (MYO5A) interaction partners

  1. Rab11 (show RAB11A Proteins) and the associated motor protein Myosin V play essential roles in both endogenous and ectopic apical constriction, and might be involved in Vangl2 trafficking to the cell surface.

Mouse (Murine) Myosin VA (MYO5A) interaction partners

  1. function of two coupled myosin va motors on actin filaments and bundles

  2. MyoVa-Ca(2 (show CA2 Proteins)+) channel interactions are required for proper long-range axon growth in developing spinal cord in vivo.

  3. Myo5c-globular tail domain and Myo5a-globular tail domain are not interchangeable in terms of inhibiting the motor function.

  4. This study showed that spontaneous Myo5a mutations causing cerebellar pathology are impaired in motor functions during the neonatal period.

  5. These results visualize many of the critical unknown aspects of the stepping mechanism of myosin 5 including head-head coordination, the origin of lever-arm motion and the spatiotemporal dynamics of the translocating head during individual steps.

  6. Motor coupling through lipid membranes enhances transport velocities for ensembles of myosin Va.

  7. Microtubules retard a centrifugal transport process that is dependent on myosin-Va and a population of dynamic F-actin. Functional analysis of mutant proteins indicates that myosin-Va works as a transporter dispersing melanosomes along actin tracks.

  8. Normal physiological processes of relaxation of gastric and cavernosal smooth muscles that facilitate food accommodation and penile erection, respectively, may be disrupted under conditions of myosin Va deficiency.

  9. Data demonstrate that myosin-Va is a component of a heterogeneous population of ribonucleoprotein particles of different sizes and composition, both in brain and peripheral nervous system

  10. Myosin Va associates with FMRP (show FMR1 Proteins) and is required for its correct intracellular localisation.

Human Myosin VA (MYO5A) interaction partners

  1. the inhibited Myo5a is equilibrated between the folded state, in which the Mlph (show MLPH Proteins)-binding site is buried, and the preactivated state, in which the Mlph (show MLPH Proteins)-binding site is exposed, and that Mlph (show MLPH Proteins) is able to bind to the Myo5a in preactivated state and activates its motor function.

  2. These findings reveal a new fast-acting energy conservation strategy halting growth by immobilizing myosin V in a newly described state on selectively stabilized actin cables.

  3. Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.

  4. Data indicate that myosin Va interacted with multiple new Rab (show HRB Proteins) subfamilies including Rab6 (show RAB6A Proteins), Rab14 (show RAB14 Proteins) and Rab39B (show RAB39B Proteins).

  5. several crystal structures of the myosin Va or the myosin Vb globular tail domain that gives insights into how the motor is linked to the recycling membrane compartments via Rab11 (show RAB11A Proteins) or the melanophilin (show MLPH Proteins) adaptor that binds to Rab27a (show RAB27A Proteins).

  6. the cargo-binding domain (CBD (show OPN1MW Proteins)) structures of the three human MyoV paralogs (Va, Vb, and Vc), revealing subtle structural changes that drive functional differentiation and a novel redox mechanism controlling the CBD (show OPN1MW Proteins) dimerization process

  7. myosin-Va promotes adhesion dynamics, anchorage-independent survival, migration, and invasion in vitro

  8. Myosin Va plays a role in the transport and turnover of mRNA. [Review]

  9. Calmodulin (show CALM1 Proteins) bound to the first IQ motif is responsible for calcium-dependent regulation of myosin 5a.

  10. A Rab27a (show RAB27A Proteins)/MyRIP (show MYRIP Proteins)/myosin Va complex is involved in linking von-Willebrand factor (Vwf (show VWF Proteins)) to the peripheral actin cytoskeleton of endothelial cells to allow full maturation and prevent premature secretion of vWF (show VWF Proteins).

Cow (Bovine) Myosin VA (MYO5A) interaction partners

  1. Calmodulin (show KRIT1 Proteins) bound to the first IQ motif is responsible for calcium-dependent regulation of myosin 5a.

MYO5A Protein Profile

Protein Summary

This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

Alternative names and synonyms associated with MYO5A

  • myosin VA (heavy polypeptide 12, myoxin) (myo5a)
  • myosin VAa (myo5aa)
  • myosin VA (MYOA)
  • myosin Va (MYO5A)
  • myosin va (PY04789)
  • myosin VA (Myo5a)
  • myosin VA (heavy chain 12, myosin) (MYO5A)
  • myosin VA (heavy chain 12, myoxin) (MYO5A)
  • 9630007J19Rik protein
  • AI413174 protein
  • AI661011 protein
  • d protein
  • d-120J protein
  • Dbv protein
  • DILUTE protein
  • Dop protein
  • flail protein
  • flr protein
  • GS1 protein
  • MGC53270 protein
  • MVa protein
  • MYH12 protein
  • MYO5 protein
  • MYO5A protein
  • MYOA protein
  • MyoVA protein
  • myoxin) protein
  • MYR12 protein
  • non-muscle protein
  • Sev-1 protein
  • si:dkey-266j9.1 protein

Protein level used designations for Myosin VA Proteins (MYO5A)

myosin VA , heavy polypeptide 12 , myosin VA (heavy polypeptide 12, myoxin) , myosin-Va , myoxin , myosin Va , myosin va , dilute myosin heavy chain, non-muscle , dilute-opisthotonus , myosin 5a , unconventional myosin-Va , dilute lethal-20J protein , flailer , myosin 5A , myosin I heavy chain isoform , myosin VA (heavy chain 12, myoxin) , myosin heavy chain P190 , myosin-V , myosin V , myosin, heavy polypeptide kinase , myosin-12

380409 Xenopus laevis
562188 Danio rerio
574273 Macaca mulatta
594849 Sus scrofa
3790476 Plasmodium yoelii yoelii 17XNL
25017 Rattus norvegicus
17918 Mus musculus
396237 Gallus gallus
4644 Homo sapiens
478312 Canis lupus familiaris
541234 Bos taurus
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