Browse our anti-Myotubularin Related Protein 2 (MTMR2) Antibodies

Full name:
anti-Myotubularin Related Protein 2 Antibodies (MTMR2)
On are 52 Myotubularin Related Protein 2 (MTMR2) Antibodies from 15 different suppliers available. Additionally we are shipping Myotubularin Related Protein 2 Proteins (7) and many more products for this protein. A total of 65 Myotubularin Related Protein 2 products are currently listed.
6030445P13Rik, CMT4B, CMT4B1, DKFZp459I198, MTMR2, zgc:153915
list all antibodies Gene Name GeneID UniProt
MTMR2 8898 Q13614
MTMR2 77116 Q9Z2D1
MTMR2 315422  

Show all species

Show all synonyms

Most Popular Reactivities for anti-Myotubularin Related Protein 2 (MTMR2) Antibodies

Select your species and application

anti-Human Antibodies:

anti-Mouse (Murine) Antibodies:

anti-Rat (Rattus) Antibodies:

All available anti-Myotubularin Related Protein 2 Antibodies

Go to our pre-filtered search.

Top referenced anti-Myotubularin Related Protein 2 Antibodies

  1. Human Monoclonal MTMR2 Primary Antibody for ELISA, WB - ABIN563874 : Bolis, Coviello, Visigalli, Taveggia, Bachi, Chishti, Hanada, Quattrini, Previtali, Biffi, Bolino: Dlg1, Sec8, and Mtmr2 regulate membrane homeostasis in Schwann cell myelination. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)

More Antibodies against Myotubularin Related Protein 2 Interaction Partners

Human Myotubularin Related Protein 2 (MTMR2) interaction partners

  1. The expression of the endogenous transcript is induced in a heterologous cell line by ectopically expressing SOX10 (show SOX10 Antibodies), and is nearly ablated in Schwann cells by impairing SOX10 (show SOX10 Antibodies) function. Intriguingly, overexpressing the two MTMR2 protein isoforms in HeLa cells revealed that both localize to nuclear puncta and the shorter isoform displays higher nuclear localization compared to the longer isoform

  2. we identified a novel mutation in MTMR2 in a family with CMT4B1 and myelin outfoldings

  3. these results reveal that MTMR2 compartmentalization and potential subsequent effects on endosome maturation and endosome signaling are dynamically regulated through MAPK (show MAPK1 Antibodies)-mediated differential phosphorylation events.

  4. Mutations in LITAF (show LITAF Antibodies), RAB7 (show RAB7B Antibodies), LMNA (show LMNA Antibodies), and MTMR2 genes are rare in Chinese Charcot-Marie-Tooth disease (CMT) patients.

  5. Novel mutations in the PRX (show PRDX6 Antibodies) and the MTMR2 genes are responsible for unusual Charcot-Marie-Tooth disease phenotypes.

  6. MTMR2 phosphorylation is likely to be a critical mechanism by which MTMR2 access to its lipid substrate(s) is temporally and spatially regulated, thereby contributing to the control of downstream endosome maturation events.

  7. MTMR2 shares similar phosphatase activity and substrate specificity than its homologous proteins MTM1 (show MTM1 Antibodies) and MTMR3 (show MTMR3 Antibodies)

  8. REVIEW : MTMR2 belongs to the myotubularin (show MTM1 Antibodies) family of phosphoinositides phosphatases

  9. Loss of MTMR2, by decreasing Schwann cells proliferation and survival, may impair the first stages of myelination of the peripheral nervous system

  10. REVIEW : MTMR2 and homologous proteins are mutated in several neuromuscular diseases

Mouse (Murine) Myotubularin Related Protein 2 (MTMR2) interaction partners

  1. Mtmr2 and Mtmr13 depend upon each other to achieve wild-type levels of protein expression. Mtmr2 stabilizes Mtmr13 on membranes, indicating that the Mtmr13 pseudophosphatase is regulated by its catalytically active binding partner.

  2. data indicate that Mtmr2 and Mtmr13/Sbf2 play critical roles in the sorting and modulation of cellular signalling which are likely to be disturbed in Charcot-Marie-Tooth disease type 4B

  3. Here we provide strong evidence that Mtmr2 and Fig4 (show FIG4 Antibodies) functionally interact in both Schwann cells and neurons, and we reveal for the first time a role of Mtmr2 in neurons in vivo

  4. Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1

  5. Mtmr2 forms a dimer and the C-terminal coiled-coil is responsible for homodimerization, in addition to membrane association

  6. Schwann cell-autonomous loss of Mtmr2-Dlg1 (show DLG1 Antibodies) interaction dysregulates membrane homeostasis in the paranodal region, thereby producing outfolding and recurrent loops of myelin.

  7. Loss of Mtmr2 in Schwann cells, but not in motor neurons, is both sufficient and necessary to cause Charcot-Marie-Tooth type neuropaathy.

  8. Interaction of Discs large 1 (Dlg1 (show DLG4 Antibodies)) with the Sec8 (show EXOC4 Antibodies) exocyst component promotes membrane addition, whereas with Mtmr2, negatively regulates membrane formation.

Myotubularin Related Protein 2 (MTMR2) Antigen Profile

Antigen Summary

This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.

Alternative names and synonyms associated with Myotubularin Related Protein 2 (MTMR2)

  • myotubularin related protein 2 (MTMR2) antibody
  • myotubularin related protein 2 (Mtmr2) antibody
  • myotubularin related protein 2 (mtmr2) antibody
  • 6030445P13Rik antibody
  • CMT4B antibody
  • CMT4B1 antibody
  • DKFZp459I198 antibody
  • MTMR2 antibody
  • zgc:153915 antibody

Protein level used designations for MTMR2

myotubularin related protein 2 , myotubularin-related protein 2 , myotubularin-related protein 2-like , Myotubularin-related protein 2

100080246 Ornithorhynchus anatinus
100352381 Oryctolagus cuniculus
100473901 Ailuropoda melanoleuca
451498 Pan troglodytes
606918 Canis lupus familiaris
699703 Macaca mulatta
100174264 Pongo abelii
100404569 Callithrix jacchus
8898 Homo sapiens
77116 Mus musculus
315422 Rattus norvegicus
536810 Bos taurus
418992 Gallus gallus
100518140 Sus scrofa
30644 Danio rerio
Selected quality suppliers for anti-Myotubularin Related Protein 2 (MTMR2) Antibodies
Did you look for something else?