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Browse our FOXA1 Proteins (FOXA1)

Full name:
Forkhead Box A1 Proteins (FOXA1)
On www.antibodies-online.com are 9 Forkhead Box A1 (FOXA1) Proteins from 5 different suppliers available. Additionally we are shipping FOXA1 Antibodies (346) and many more products for this protein. A total of 363 FOXA1 products are currently listed.
Synonyms:
Ci-fkh, fkd7, fkh, fkh1, fkh2, forkhead-7, Foxa1, foxa3, FoxA4a, Hnf-3a, HNF3-alpha, HNF3A, HNF3alpha, pintallavis, Tcf-3a, Tcf3a, tFoxA1, XFD-1, xfkh1, xfkh2, xkfh-1
list all proteins Gene Name GeneID UniProt
FOXA1 3169 P55317
FOXA1 15375 P35582
FOXA1 25098 P23512

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FOXA1 Proteins (FOXA1) by Origin

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Human Forkhead Box A1 (FOXA1) interaction partners

  1. conclusion, our results demonstrated that miR24 inhibits breast cancer cells invasion by targeting OGT (show OGT Proteins) and reducing FOXA1 stability. These results also indicated that OGT (show OGT Proteins) might be a potential target for the diagnosis and therapy of breast cancer metastasis.

  2. FOXA1 is not only able to recognize but also remodel the epigenetic signatures at lineage-specific enhancers, which is mediated, at least in part, by a feed-forward regulatory loop between FOXA1 and TET1 (show TET1 Proteins).

  3. Based on these results, we suggest that FOXA1 plays a catalytic role in ovarian cancer pathogenesis and development by affecting the expression of the above-mentioned proteins.

  4. these results suggest that FOXA1 suppresses expression of IL6 (show IL6 Proteins) through inhibition of NF-kappaB (show NFKB1 Proteins) recruitment to the IL6 (show IL6 Proteins) promoter in an ERalpha (show ESR1 Proteins)-independent manner and that reduction in FOXA1 expression induces IL6 (show IL6 Proteins) expression and contributes to cancer stem cell-like properties in TAM (show CCNA1 Proteins)-R cells.

  5. These results suggest a positional-nucleosome-oriented accessing model for Pioneer factors seeking target motifs, in which FOXA1 can examine each underlying DNA nucleotide.

  6. Down-regulation of TRPS1 by miR (show MLXIP Proteins)-373, acting as a transcriptional activator, promotes epithelial-mesenchymal transition (EMT (show ITK Proteins)) and metastasis by repressing FOXA1 transcription, expanding upon its previously reported role as a transcription repressor.

  7. FOXA1 is found in ovarian mucinous and Brenner tumours

  8. the results of the present study indicated that FOXA1 may be considered a potential prognostic marker, and may promote tumor growth of CRC (show CALR Proteins) by upregulating YAP (show YAP1 Proteins) expression.

  9. meta-analysis showed that high expression of FOXA1 in breast cancer patients was a good prognostic indicator for survival outcome.

  10. FOXA1 promotes cell senescence in EC by interaction with p16INK4a.

Mouse (Murine) Forkhead Box A1 (FOXA1) interaction partners

  1. this model system will facilitate further in vivo functional studies of Foxa1 or other factors in mammary gland development and tumor formation and progression

  2. Loss of Interdependent Binding by the FoxO1 (show FOXO1 Proteins) and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin (show INS Proteins)-sensitive Genes.

  3. FoxA1, FoxA2 (show FOXA2 Proteins), and LIPG (show LIPG Proteins) control the uptake of extracellular lipids for breast cancer growth.

  4. genome-wide binding sites of the forkhead/winged helix transcription factor (show FOXP2 Proteins) Foxa1, which functions redundantly with Foxa2 (show FOXA2 Proteins) to regulate the differentiation of midbrain dopamine neurons, were characterized.

  5. Disruption of Shp (show LAMC1 Proteins) in mice alters timing of expression of genes that regulate homocysteine metabolism and the liver responses to ethanol and homocysteine. SHP (show LAMC1 Proteins) inhibits the transcriptional activation of Bhmt (show BHMT Proteins) and cystathionine gamma-lyase (show CTH Proteins) by FOXA1.

  6. ChIP-exonuclease of the ER pioneer factor FoxA1 identifies protected DNA with a predictable 8 bp overhang from the Forkhead motif, which authors term mesas; showed that mesas occur in multiple cellular contexts and exist as single or overlapping motifs.

  7. TIP30 (show HTATIP2 Proteins) is a key regulator for maintaining ER(+) and ER(-)luminal pools in the mammary luminal lineage via FoxA1.

  8. Mechanistically, JARID1B (show KDM5B Proteins) was required for GATA3 (show GATA3 Proteins) recruitment to the Foxa1 promoter to activate Foxa1 expression.

  9. Foxa1 recruited Grg3 to the Nanog (show NANOG Proteins) promoter -2kb upstream region and switched the promoter to an inactive chromatin status represented by typical modifications in histone H3 (show HIST3H3 Proteins).

  10. Results indicate Foxa1 expression is required for the maintenance of prostatic cellular differentiation.

FOXA1 Protein Profile

Protein Summary

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.

Alternative names and synonyms associated with FOXA1

  • forkhead box A4 (foxa4)
  • forkhead box A1 (foxa1)
  • forkhead homolog (fkh)
  • forkhead box A1 (FOXA1)
  • Me-FKH1 (foxa3)
  • forkhead box A1 (LOC100301627)
  • forkhead box A1 (foxa1-b)
  • forkhead box A1 (Foxa1)
  • Ci-fkh protein
  • fkd7 protein
  • fkh protein
  • fkh1 protein
  • fkh2 protein
  • forkhead-7 protein
  • Foxa1 protein
  • foxa3 protein
  • FoxA4a protein
  • Hnf-3a protein
  • HNF3-alpha protein
  • HNF3A protein
  • HNF3alpha protein
  • pintallavis protein
  • Tcf-3a protein
  • Tcf3a protein
  • tFoxA1 protein
  • XFD-1 protein
  • xfkh1 protein
  • xfkh2 protein
  • xkfh-1 protein

Protein level used designations for Forkhead Box A1 Proteins (FOXA1)

forkhead box A1 , forkhead box protein A4 , HNF-3 alpha , HNF3 alpha , forkhead box protein A1 , forkhead transcription factor FoxA1 , forkhead homolog , Me-FKH1 , hepatocyte nuclear factor 3-alpha-like , fork head domain protein 7 , hepatocyte nuclear factor 3-alpha , FKH-2 , HNF3alpha homolog B , fork head domain-related protein 7' , forkhead box protein A1-B , forkhead protein 2 , foxA1b , hepatocyte nuclear factor 3-alpha homolog B , xFD-7' , xFKH2 , xHNF3alpha-B , HNF-3-alpha , HNF-3A , TCF-3A , transcription factor 3A , hepatocyte nuclear factor 3 alpha , fork head domain , hepatocyte nuclear factor 3 alpha (winged helix transcription factor) , hepatocyte nuclear factor 3, alpha

GENE ID SPECIES
394535 Xenopus (Silurana) tropicalis
395059 Xenopus (Silurana) tropicalis
445664 Ciona intestinalis
737693 Pan troglodytes
100049257 Oryzias latipes
100125667 Xenopus laevis
100462038 Pongo abelii
100301627 Oryzias latipes
30541 Danio rerio
379755 Xenopus laevis
3169 Homo sapiens
490657 Canis lupus familiaris
503579 Bos taurus
15375 Mus musculus
25098 Rattus norvegicus
101752179 Gallus gallus
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