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Browse our FOXA1 Proteins (FOXA1)

Full name:
Forkhead Box A1 Proteins (FOXA1)
On www.antibodies-online.com are 9 Forkhead Box A1 (FOXA1) Proteins from 5 different suppliers available. Additionally we are shipping FOXA1 Antibodies (344) and many more products for this protein. A total of 361 FOXA1 products are currently listed.
Synonyms:
Ci-fkh, fkd7, fkh, fkh1, fkh2, forkhead-7, Foxa1, foxa3, FoxA4a, Hnf-3a, HNF3-alpha, HNF3A, HNF3alpha, pintallavis, Tcf-3a, Tcf3a, tFoxA1, XFD-1, xfkh1, xfkh2, xkfh-1
list all proteins Gene Name GeneID UniProt
FOXA1 3169 P55317
FOXA1 15375 P35582
FOXA1 25098 P23512

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FOXA1 Proteins (FOXA1) by Origin

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More Proteins for FOXA1 Interaction Partners

Human Forkhead Box A1 (FOXA1) interaction partners

  1. There is significantly increased esophageal squamous cell carcinoma risk associated with the FOXA1 rs7144658 T > C polymorphism among male patients.

  2. Meta-analysis results clearly point to an important role of FOXA1 and FOXA2 (show FOXA2 Proteins) gene regulatory networks in the etiology of Alzheimer's disease

  3. show that ER and GR both have the ability to alter the genomic distribution of the FoxA1 pioneer factor. Single-molecule tracking experiments reveal a highly dynamic interaction of FoxA1 with chromatin in vivo; FoxA1 factor is not associated with footprints at its binding sites throughout the genome; findings support a model wherein interactions between transcription factors and pioneer factors are highly dynamic.

  4. findings suggest a key role for GalNAc-T4 (show GALNT4 Proteins) in the estrogen pathway through FOXA1 glycosylation

  5. The ratio of FoxA1 to FoxA2 (show FOXA2 Proteins) in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor (show ASH1L Proteins) LSH (show HELLS Proteins)

  6. Loss of Interdependent Binding by the FoxO1 (show FOXO1 Proteins) and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin (show INS Proteins)-sensitive Genes.

  7. FoxA1, FoxA2 (show FOXA2 Proteins), and LIPG (show LIPG Proteins) control the uptake of extracellular lipids for breast cancer growth.

  8. The expression of FOXA1 appears to be involved in the proliferation of immature breast cancer cells rather than the induction of stemness-related genes and self-renewal potency of cancer stem cells.

  9. Data suggests that androgen receptor (show AR Proteins) variants (AR-Vs) are dependent on forkhead box A1 protein (FOXA1) for sustaining a pro-proliferative gene signature.

  10. FOXA1 expression is associated with a less aggressive phenotype and a better prognosis in patients with hormone receptor (show NR4A1 Proteins)-positive/HER2 (show ERBB2 Proteins)-negative breast cancer.

Mouse (Murine) Forkhead Box A1 (FOXA1) interaction partners

  1. this model system will facilitate further in vivo functional studies of Foxa1 or other factors in mammary gland development and tumor formation and progression

  2. Loss of Interdependent Binding by the FoxO1 (show FOXO1 Proteins) and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin (show INS Proteins)-sensitive Genes.

  3. FoxA1, FoxA2 (show FOXA2 Proteins), and LIPG (show LIPG Proteins) control the uptake of extracellular lipids for breast cancer growth.

  4. genome-wide binding sites of the forkhead/winged helix transcription factor (show FOXP2 Proteins) Foxa1, which functions redundantly with Foxa2 (show FOXA2 Proteins) to regulate the differentiation of midbrain dopamine neurons, were characterized.

  5. Disruption of Shp (show LAMC1 Proteins) in mice alters timing of expression of genes that regulate homocysteine metabolism and the liver responses to ethanol and homocysteine. SHP (show LAMC1 Proteins) inhibits the transcriptional activation of Bhmt (show BHMT Proteins) and cystathionine gamma-lyase (show CTH Proteins) by FOXA1.

  6. ChIP-exonuclease of the ER pioneer factor FoxA1 identifies protected DNA with a predictable 8 bp overhang from the Forkhead motif, which authors term mesas; showed that mesas occur in multiple cellular contexts and exist as single or overlapping motifs.

  7. TIP30 (show HTATIP2 Proteins) is a key regulator for maintaining ER(+) and ER(-)luminal pools in the mammary luminal lineage via FoxA1.

  8. Mechanistically, JARID1B (show KDM5B Proteins) was required for GATA3 (show GATA3 Proteins) recruitment to the Foxa1 promoter to activate Foxa1 expression.

  9. Foxa1 recruited Grg3 to the Nanog (show NANOG Proteins) promoter -2kb upstream region and switched the promoter to an inactive chromatin status represented by typical modifications in histone H3 (show HIST3H3 Proteins).

  10. Results indicate Foxa1 expression is required for the maintenance of prostatic cellular differentiation.

FOXA1 Protein Profile

Protein Summary

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.

Alternative names and synonyms associated with FOXA1

  • forkhead box A4 (foxa4)
  • forkhead box A1 (foxa1)
  • forkhead homolog (fkh)
  • forkhead box A1 (FOXA1)
  • Me-FKH1 (foxa3)
  • forkhead box A1 (LOC100301627)
  • forkhead box A1 (foxa1-b)
  • forkhead box A1 (Foxa1)
  • Ci-fkh protein
  • fkd7 protein
  • fkh protein
  • fkh1 protein
  • fkh2 protein
  • forkhead-7 protein
  • Foxa1 protein
  • foxa3 protein
  • FoxA4a protein
  • Hnf-3a protein
  • HNF3-alpha protein
  • HNF3A protein
  • HNF3alpha protein
  • pintallavis protein
  • Tcf-3a protein
  • Tcf3a protein
  • tFoxA1 protein
  • XFD-1 protein
  • xfkh1 protein
  • xfkh2 protein
  • xkfh-1 protein

Protein level used designations for Forkhead Box A1 Proteins (FOXA1)

forkhead box A1 , forkhead box protein A4 , HNF-3 alpha , HNF3 alpha , forkhead box protein A1 , forkhead transcription factor FoxA1 , forkhead homolog , Me-FKH1 , hepatocyte nuclear factor 3-alpha-like , fork head domain protein 7 , hepatocyte nuclear factor 3-alpha , FKH-2 , HNF3alpha homolog B , fork head domain-related protein 7' , forkhead box protein A1-B , forkhead protein 2 , foxA1b , hepatocyte nuclear factor 3-alpha homolog B , xFD-7' , xFKH2 , xHNF3alpha-B , HNF-3-alpha , HNF-3A , TCF-3A , transcription factor 3A , hepatocyte nuclear factor 3 alpha , fork head domain , hepatocyte nuclear factor 3 alpha (winged helix transcription factor) , hepatocyte nuclear factor 3, alpha

GENE ID SPECIES
394535 Xenopus (Silurana) tropicalis
395059 Xenopus (Silurana) tropicalis
445664 Ciona intestinalis
737693 Pan troglodytes
100049257 Oryzias latipes
100125667 Xenopus laevis
100462038 Pongo abelii
100301627 Oryzias latipes
30541 Danio rerio
379755 Xenopus laevis
3169 Homo sapiens
490657 Canis lupus familiaris
503579 Bos taurus
15375 Mus musculus
25098 Rattus norvegicus
101752179 Gallus gallus
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