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the Trip6-GRIP1-myosin VI interaction and its regulation on F-actin network play a significant role in dendritic morphogenesis
In 15 of 590 families, we identified recessive mutations in the genes FRAS1 (show FRAS1 ELISA Kits), FREM2 (show FREM2 ELISA Kits), GRIP1 (show NCOA2 ELISA Kits), FREM1 (show FREM1 ELISA Kits), ITGA8, and GREM1 (show GREM1 ELISA Kits), all of which function in the interaction of the ureteric bud and the metanephric mesenchyme.
In three unrelated families with parental consanguinity, GRIP1 (show NCOA2 ELISA Kits) mutations were found to segregate with Fraser syndrome in an autosomal recessive manner.
Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 (show GRIA2 ELISA Kits) recycling and surface distribution in patients with autism
GRIP1 (show NCOA2 ELISA Kits) splice forms interact with gephyrin (show GPHN ELISA Kits) and play a role in synaptic function at GABAergic and glycinergic synapses in cultured hippocampal neurons.
after regulated endocytosis, binding to GRIP/ABP (show ABP1 ELISA Kits) stabilizes the internalized receptors in an intracellular pool and prevents them from being recycled back to the plasma membrane or entering a degradative pathway.
study showed neither single marker nor haplotype analysis revealed an association between variants at GRIP1 (show NCOA2 ELISA Kits) locus & schizophrenia; suggests it is unlikely that the GRIP1 (show NCOA2 ELISA Kits) polymorphisms investigated play a substantial role in schizophrenia susceptibility
Supramodular nature of GRIP1 (show NCOA2 ELISA Kits) revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1 (show FRAS1 ELISA Kits).
Study performed social behavioral testing on neuron-specific Grip1/2-double knockout (DKO) and wild type (WT) mice and determined the expression profile of key signaling proteins in AMPAR, mGluR, mTOR, and GABA pathways in brain. Data Grip1/2-mediated AMPA signaling in regulating social behaviors and disturbance of glutamate- and GABA-signaling in specialized brain regions in autism-related social behavioral deficits.
subcellular redistribution of GRIP1 (show NCOA2 ELISA Kits) and a change in the binding of GRIP1 (show NCOA2 ELISA Kits) to GluA2 (show GRIA2 ELISA Kits) during synaptic scaling, was observed.
This study demonistrated that deletion of accumbal GRIP1 increases vulnerability to cue-induced cocaine relapse without altering the reinforcing properties of the drug or the response to natural rewards
a regulatory role for GRIP1 (show NCOA2 ELISA Kits) during microtubule-based transport and suggest a crucial function for 14-3-3 (show YWHAQ ELISA Kits) proteins in controlling kinesin-1 motor attachment during neuronal development
Data indicate that glucocorticoid receptor (GR (show NR3C1 ELISA Kits)):GRIP1 (show NCOA2 ELISA Kits) use distinct mechanisms to repress inflammatory genes at different stages of the transcription cycle.
GRIP1 (show NCOA2 ELISA Kits) and 2 regulate activity-dependent AMPA (show GRIA3 ELISA Kits) receptor recycling via exocyst complex interactions.
GRIP1 (show NCOA2 ELISA Kits) scaffolding protein is required for the formation and integrity of the dermo-epidermal junction and reveal the importance of PDZ (show INADL ELISA Kits) domains in the organization of supramolecular structures essential for mammalian embryonic development.
Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites.
morphology of octopus cell (OC) somata in the cochlear nucleus B6 and B6Cast mice, and the immunocytochemistry of GluR1 (show GRIA1 ELISA Kits) (glutamate (show GRIN1 ELISA Kits) receptor subunit 1) and GRIP-C (glutamate (show GRIN1 ELISA Kits) receptor interacting protein (show RIPK1 ELISA Kits)-C (show PROC ELISA Kits) terminus).
investigated whether there is a link between growth inhibitory effect and transcriptional activation of PPARgamma (show PPARG ELISA Kits) in several gastrointestinal tumour cell lines [GRIP1tau]
lactoferrin (show LTF ELISA Kits) and glutamate receptor-interacting protein 1 showed a twofold increase during the controlled internal drug release -induced estrous stage compared to the levels in non-estrous stage in bovine cervical mucus
This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
glutamate receptor-interacting protein 1
, eye blebs
, AMPA receptor-interacting protein GRIP1
, glutamate receptor interacting protein 1
, glutamate receptor-interacting protein 1-like