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Nuclear Receptor Coactivator 1 ELISA Kits (NCOA1)
On are 6 Nuclear Receptor Coactivator 1 (NCOA1) ELISA Kits from 4 different suppliers available. Additionally we are shipping NCOA1 Antibodies (120) and NCOA1 Proteins (9) and many more products for this protein. A total of 139 NCOA1 products are currently listed.
bHLHe42, bHLHe74, c-src, C-src1, CG7524, csrc, D-src, D-Src64B, DKFZp459C083, Dmel\CG7524, DmHD-358, Dm SRC1, dsrc, Dsrc64, Dsrc64B, F-SRC-1, HD-358, KAT13A, MGC128615, MRE5, NCOA1, pp60c-src, pp60v-src, RIP160, si:dkey-5g7.6, si:dkey-34f16.6, SRA1, src, src-1, src1, src2, src64, SRC 64B, src64b, xsrc, zgc:86613
list all ELISA KIts Gene Name GeneID UniProt
NCOA1 8648 Q15788
NCOA1 17977 P70365
Rat NCOA1 NCOA1 313929  

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Xenopus laevis Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. The structural and functional competency of the UPIII (show UPK3A ELISA Kits)-Src (show SRC ELISA Kits) signaling system in membrane microdomains is strictly regulated during oocyte maturation.

Human Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. Data suggest that steroid receptor (show ESR2 ELISA Kits) coactivators (NCOA1, NCOA2 (show NCOA2 ELISA Kits), NCOA3 (show NCOA3 ELISA Kits)) are over-expressed in a number of hormone-dependent cancers where they promote tumor growth, invasion, metastasis, and chemo-resistance; with their multiple roles in cancer, steroid receptor (show ESR2 ELISA Kits) coactivators are promising targets for development of antineoplastic agents that can interfere with their function. [REVIEW]

  2. The mechanism of IL-6-induced AR activation is mediated through enhancing AR-SRC-1 interaction and inhibiting AR-SMRT interaction.

  3. IL-6-mediated AR antagonism induced by cypermethrin is related to repress the recruitment of co-regulators SRC-1 and SMRT to the AR in a ligand-independent manner

  4. NCOA1 potentiates breast cancer angiogenesis through upregulating HIF1alpha (show HIF1A ELISA Kits) and AP-1 (show FOSB ELISA Kits)-mediated VEGFa (show VEGFA ELISA Kits) expression

  5. miR (show MLXIP ELISA Kits)-137 has a role in targeting p160 (show MSH6 ELISA Kits) steroid receptor (show ESR2 ELISA Kits) coactivators SRC1 (show SRC ELISA Kits), SRC2 (show NCOA2 ELISA Kits), and SRC3 (show NCOA3 ELISA Kits) and inhibits cell proliferation

  6. Report novel PAX3 (show PAX3 ELISA Kits)-NCOA1 gene fusions in biphenotypic sinonasal sarcomas with focal rhabdomyoblastic differentiation.

  7. Data indicate that finerenone inhibits mineralocorticoid receptor (show NR3C2 ELISA Kits) (MR), steroid receptor coactivator-1 binding at the regulatory sequence.

  8. Data suggest that over-stimulating the steroid seceptor coactivators SRC-1 (show SRC ELISA Kits), SRC-2 (show NCOA2 ELISA Kits), and SRC-3 (show NCOA3 ELISA Kits) oncogenic program can be an effective strategy to kill cancer cells.

  9. Our study clearly demonstrated differentiation-dependant expression of SRC-1 (show SRC ELISA Kits) and SRC-3 (show NCOA3 ELISA Kits) in chondrosarcoma

  10. SRC-1 (show SRC ELISA Kits) polymorphisms may be the underlying cause of coronary artery aneurysms in children with Kawasaki disease.

Mouse (Murine) Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. ubiquitination of K446 limits RORgammat-mediated Th17 differentiation by inhibiting the recruitment of coactivator SRC1

  2. Loss of SRC-1 is associated with high Blood Pressure and Aortic Stiffness.

  3. local E2 inhibition could induce aberrant actin polymerization and also showed an important role of SRC-1 in the mediation of local E2 action on hippocampal synaptic plasticity by regulation of actin cytoskeleton dynamics

  4. SRC-1/3 are required for cardiomyocyte proliferation and differentiation at earlier developmental stages, and their dysfunction causes NCC (show SLC12A3 ELISA Kits)-like abnormalities in the hearts of newborn and adult mice.

  5. While hippocampal SRC-1 was significantly downregulated by orchidectomy (ORX), its expression was rescued by treatment with testosterone in a dose-dependent manner. Testosterone regulates synaptic proteins involves AR, estrogen receptors and SRC-1.

  6. fetal lungs produce signals to initiate labor when mature, and SRC-1/-2-dependent production of SP-A (show SFTPA1 ELISA Kits) and PAF (show KIAA0101 ELISA Kits) is crucial for this process

  7. Consequently, SRC-1 null mice displayed low TAT (show TAT ELISA Kits) expression and presented with hypertyrosinemia and corneal alterations, 2 clinical features observed in the human syndrome of TAT (show TAT ELISA Kits) deficiency.

  8. the effect of orchidectomy (ORX) on the expression of SRC-1

  9. Letrozole induces dramatic decrease of SRC-1 in the medial septal, hippocampus, medial habenular nucleus, arcuate hypothalamic nucleus and superior colliculus.

  10. SRC1 regulates anxiety responses in male and female mice.

Pig (Porcine) Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. we cloned and sequenced full length cDNA of NCOA-1 gene in pig. The putative protein includes 1440 amino acids. Sequences alignment showed that pig NCOA-1 gene cDNA sequence has identity of 93.73% with human and mouse.

Fruit Fly (Drosophila melanogaster) Nuclear Receptor Coactivator 1 (NCOA1) interaction partners

  1. Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo

  2. that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction

  3. Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation.

  4. a novel essential role for Src (show SRC ELISA Kits) in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo.

  5. Data show that the actin-Capping Protein (show TMOD4 ELISA Kits) (CP) alphabeta heterodimer, which regulates actin (show ACTB ELISA Kits) filament (F-actin (show ACTB ELISA Kits)) polymerization, limits Src (show SRC ELISA Kits)-induced apoptosis or tissue overgrowth by restricting JNK (show MAPK8 ELISA Kits) activation.

  6. Dumbfounded/Neph1 (show NEPH1 ELISA Kits), a key diaphragm constituent, is a target of the Src kinase (show CSK ELISA Kits) Src64B. Loss of Src64B activity leads to a reduction in the number of diaphragms, and this effect is in part mediated by loss of Dumbfounded/Neph1 (show NEPH1 ELISA Kits) tyrosine phosphorylation.

  7. Homodimerization of the Wnt receptor DERAILED recruits the Src (show SRC ELISA Kits) family kinase SRC64B in the developing embryonic central nervous system.

  8. E4orf4 has a role in inducing PP2A- and Src (show SRC ELISA Kits)-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster

  9. Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified.

  10. Src64B overexpression induced the formation of specialized haemocytes (lamellocytes), but had no effect on circulating plasmatocyte concentration. Src64B overexpression induced F-actin (show ACTB ELISA Kits) formation and Jun kinase (show MAPK9 ELISA Kits) activation in plasmatocytes.

NCOA1 Antigen Profile

Antigen Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with NCOA1

  • nuclear receptor coactivator 1 (NCOA1) Elisa Kit
  • nuclear receptor coactivator 1 (ncoa1) Elisa Kit
  • steroid receptor RNA activator 1 (sra1) Elisa Kit
  • steroid receptor RNA activator 1 (SRA1) Elisa Kit
  • steroid receptor RNA activator 1 (LOC100345921) Elisa Kit
  • nuclear receptor coactivator 1 (Ncoa1) Elisa Kit
  • Src oncogene at 64B (Src64B) Elisa Kit
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (src-b) Elisa Kit
  • bHLHe42 Elisa Kit
  • bHLHe74 Elisa Kit
  • c-src Elisa Kit
  • C-src1 Elisa Kit
  • CG7524 Elisa Kit
  • csrc Elisa Kit
  • D-src Elisa Kit
  • D-Src64B Elisa Kit
  • DKFZp459C083 Elisa Kit
  • Dmel\CG7524 Elisa Kit
  • DmHD-358 Elisa Kit
  • Dm SRC1 Elisa Kit
  • dsrc Elisa Kit
  • Dsrc64 Elisa Kit
  • Dsrc64B Elisa Kit
  • F-SRC-1 Elisa Kit
  • HD-358 Elisa Kit
  • KAT13A Elisa Kit
  • MGC128615 Elisa Kit
  • MRE5 Elisa Kit
  • NCOA1 Elisa Kit
  • pp60c-src Elisa Kit
  • pp60v-src Elisa Kit
  • RIP160 Elisa Kit
  • si:dkey-5g7.6 Elisa Kit
  • si:dkey-34f16.6 Elisa Kit
  • SRA1 Elisa Kit
  • src Elisa Kit
  • src-1 Elisa Kit
  • src1 Elisa Kit
  • src2 Elisa Kit
  • src64 Elisa Kit
  • SRC 64B Elisa Kit
  • src64b Elisa Kit
  • xsrc Elisa Kit
  • zgc:86613 Elisa Kit

Protein level used designations for NCOA1

nuclear receptor coactivator 1 , DKEY-34F16.7 , SRC1 , steroid receptor RNA activator 1 , Hin-2 protein , PAX3/NCOA1 fusion protein , class E basic helix-loop-helix protein 74 , renal carcinoma antigen NY-REN-52 , steroid receptor coactivator-1 , NCoA-1 , SRC-a/NCoA-1 , mNRC-1 , nuclear receptor coactivator protein 1 , steroid receptor coactivator 1 , SRC-1 , CG7524-PB , CG7524-PC , CG7524-PD , CG7524-PE , CG7524-PF , CG7524-PG , CG7524-PH , CG7524-PI , CG7524-PJ , Src proto oncogene sequence , Src64B-PB , Src64B-PC , Src64B-PD , Src64B-PE , Src64B-PF , Src64B-PG , Src64B-PH , Src64B-PI , Src64B-PJ , mRNA-like ncRNA in embryogenesis 5 , p60-Src-2 , tyrosine protein kinase pp60-c-src , tyrosine-protein kinase Src-2 , v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

422016 Gallus gallus
563288 Danio rerio
459068 Pan troglodytes
100025270 Monodelphis domestica
100385756 Callithrix jacchus
100471908 Ailuropoda melanoleuca
100556605 Anolis carolinensis
415137 Danio rerio
606944 Canis lupus familiaris
780787 Bos taurus
100049723 Xenopus laevis
100135196 Xenopus (Silurana) tropicalis
100173951 Pongo abelii
100345921 Oryctolagus cuniculus
8648 Homo sapiens
17977 Mus musculus
313929 Rattus norvegicus
574068 Sus scrofa
48973 Drosophila melanogaster
380430 Xenopus laevis
475684 Canis lupus familiaris
525346 Bos taurus
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