Browse our Prostaglandin E Synthase 3 (Cytosolic) Proteins (PTGES3)

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Prostaglandin E Synthase 3 (Cytosolic) Proteins (PTGES3)
On www.antibodies-online.com are 13 Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) Proteins from 5 different suppliers available. Additionally we are shipping Prostaglandin E Synthase 3 (Cytosolic) Antibodies (129) and Prostaglandin E Synthase 3 (Cytosolic) Kits (10) and many more products for this protein. A total of 158 Prostaglandin E Synthase 3 (Cytosolic) products are currently listed.
Synonyms:
5730442A20Rik, CPGES, p23, Ptges, PTGES3, RGD1561913, sid3177, Tebp
list all proteins Gene Name GeneID UniProt
PTGES3 10728 Q15185
PTGES3 56351 Q9R0Q7
PTGES3 362809 P83868

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Prostaglandin E Synthase 3 (Cytosolic) Proteins (PTGES3) by Origin

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More Proteins for Prostaglandin E Synthase 3 (Cytosolic) Interaction Partners

Human Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) interaction partners

  1. dysregulation of GR, MR, FKBP5 (show FKBP5 Proteins), and PTGES3 in autistic spectrum disorder (ASD (show ARSD Proteins)) and suggest a possible role of inflammation in altered GR function in ASD (show ARSD Proteins).

  2. increased p23 expression may allow cells to acquire a more aggressive phenotype, contributing to disease progression

  3. Even if p23 predominantly binds the Hsp90 (show HSP90 Proteins) dimer, p23 is also able to interact with Hsp90 (show HSP90 Proteins) oligomers, shifting the Hsp90 (show HSP90 Proteins) dimer-oligomers equilibrium toward dimer.

  4. FKBP4 (show FKBP4 Proteins), p23, and Aha1 (show AHSA1 Proteins) cooperatively regulate the progression of hAgo2 (show EIF2C2 Proteins) through the chaperone cycle.

  5. p23 recruits PHD2 (show EGLN1 Proteins) to the HSP90 (show HSP90 Proteins) machinery to facilitate HIF-1alpha (show HIF1A Proteins) hydroxylation

  6. The effects of p23 on androgen receptor (AR (show AR Proteins)) activity are at least partly HSP90 (show HSP90 Proteins) independent, a mutant form of p23, unable to bind HSP90 (show HSP90 Proteins), increases AR activity.

  7. p23 co-chaperone protects the aryl hydrocarbon receptor (show AHR Proteins) from degradation

  8. As an anti-apoptotic factor, p23 is able to be a potential target for anti-leukemic therapy.

  9. Patients with severe Alzheimer disease displayed a consistent reduction in brain p23 levels. Cleavage product p19 was not seen in AD brain samples.

  10. a small increase in the expression of p23 amplifies ER-binding genome wide and, in combination with ER, elicits an invasive phenotype in breast cancer

Mouse (Murine) Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) interaction partners

  1. Skin differentiation is impaired, and both apoptosis and cell proliferation are augmented in the absence of p23 (show CDK5R1 Proteins); the consequences are a severe thinning of the stratum corneum and reduced numbers of hair follicles. Since the phenotype of p23 (show CDK5R1 Proteins)-null embryos is strikingly similar to that of embryos lacking the glucocorticoid receptor (show NR3C1 Proteins), a paradigmatic Hsp90 (show HSP90 Proteins)-p23 (show CDK5R1 Proteins) client protein, we investigated glucocorticoid signaling.

  2. Results identified two proteins P23 (show CDK5R1 Proteins) and HCLS1 (show HCLS1 Proteins), which were not known as RNA-binding proteins, exhibiting RNA-binding activity.

  3. we report the generation of transgenic mouse lines that overexpress wild-type p23 (show CDK5R1 Proteins) or uncleavable p23 (show CDK5R1 Proteins)

  4. Data support a model in which p23 and GCN5 regulate diverse multistep pathways by controlling the longevity of protein-DNA complexes.

  5. p23 (show CDK5R1 Proteins) co-chaperone protects the aryl hydrocarbon receptor (show AHR Proteins) from degradation

  6. Cleavage product p19 was not seen in brain samples from a mouse model of Alzheimer disease, but p23 and p19 were seen in hypoxic cultured cells experienceing endoplasmic reticulum stress.

  7. In cytosol only one protein called p23 (show CDK5R1 Proteins) hsp90 (show HSP90 Proteins) binds to Bax (show BAX Proteins) but the binding protein does not affect the subcellular localization and pro-apoptotic activity of Bax (show BAX Proteins).

  8. The p23 cochaperone of Hsp90, which plays a major role in glucocorticoid receptor folding and function, associates with influenza virus polymerase.

  9. Overexpression of p23 (show CDK5R1 Proteins) contributes to the development of hydronephrosis through the upregulation of the aryl hydrocarbon receptor (show AHR Proteins) pathway in vivo.

  10. prostaglandin E synthase (show PTGES Proteins) (cPGES/p23) acts as a regulatory factor for expression of a PGE2-inactivating enzyme, 15-PGDH (show HPGD Proteins)

Cow (Bovine) Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) interaction partners

Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) Protein Profile

Protein Summary

Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor- mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (By similarity).

Alternative names and synonyms associated with Prostaglandin E Synthase 3 (Cytosolic) (PTGES3)

  • prostaglandin E synthase 3 (cytosolic) (PTGES3)
  • nascent polypeptide-associated complex alpha subunit (NACA)
  • prostaglandin E synthase 3 (cytosolic) (Ptges3)
  • prostaglandin E synthase 3-like (PTGES3)
  • prostaglandin E synthase 3-like 1 (Ptges3l1)
  • prostaglandin-E synthase 3 (LOC100362627)
  • 5730442A20Rik protein
  • CPGES protein
  • p23 protein
  • Ptges protein
  • PTGES3 protein
  • RGD1561913 protein
  • sid3177 protein
  • Tebp protein

Protein level used designations for PTGES3

prostaglandin E synthase 3 (cytosolic) , nascent-polypeptide-associated complex alpha polypeptide , Hsp90 co-chaperone , cytosolic prostaglandin E synthase , cytosolic prostaglandin E2 synthase , progesterone receptor complex p23 , prostaglandin E synthase 3 , telomerase-binding protein p23 , unactive progesterone receptor, 23 kD , hsp90 co-chaperone , p23 cochaperone , sid 3177 , telomerase binding protein, p23 , cPGES , prostaglandin-E synthase 3

GENE ID SPECIES
612760 Canis lupus familiaris
743066 Pan troglodytes
396544 Gallus gallus
10728 Homo sapiens
56351 Mus musculus
362809 Rattus norvegicus
493638 Bos taurus
100174118 Pongo abelii
100859133 Gallus gallus
367808 Rattus norvegicus
100362627 Rattus norvegicus
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