Browse our anti-Ubiquitin-Conjugating Enzyme E2I (UBE2I) Antibodies

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anti-Ubiquitin-Conjugating Enzyme E2I Antibodies (UBE2I)
On are 115 Ubiquitin-Conjugating Enzyme E2I (UBE2I) Antibodies from 23 different suppliers available. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2I Proteins (36) and Ubiquitin-Conjugating Enzyme E2I Kits (13) and many more products for this protein. A total of 173 Ubiquitin-Conjugating Enzyme E2I products are currently listed.
5830467E05Rik, C358B7.1, F830028O17Rik, P18, T13J8.70, T13J8_70, ubc9, UbcE2A, Ubce2i, ubce9, ube2ia, UBIQUITIN-PROTEIN LIGASE, ubiquitin conjugating enzyme 9, zUbc9
list all antibodies Gene Name GeneID UniProt
UBE2I 7329 P63279
UBE2I 22196 P63280
UBE2I 25573 P63281

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Top referenced anti-Ubiquitin-Conjugating Enzyme E2I Antibodies

  1. Human Monoclonal UBE2I Primary Antibody for WB - ABIN387788 : Moschos, Jukic, Athanassiou, Bhargava, Dacic, Wang, Kuan, Fayewicz, Galambos, Acquafondata, Dhir, Becker: Expression analysis of Ubc9, the single small ubiquitin-like modifier (SUMO) E2 conjugating enzyme, in normal and malignant tissues. in Human pathology 2010 (PubMed)
    Show all 7 references for 387788

  2. Chicken Monoclonal UBE2I Primary Antibody for IF, IP - ABIN968154 : Buschmann, Lerner, Lee, Ronai: The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9. in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for 968154

  3. Human Polyclonal UBE2I Primary Antibody for IHC (p), WB - ABIN387910 : Watanabe, Fujiwara, Kawai, Shimizu, Takami, Hirano, Okuno, Ozaki, Takeda, Shimada, Nagata, Takaichi, Takahashi, Nakamura, Shin: Cloning, expression, and mapping of UBE2I, a novel gene encoding a human homologue of yeast ubiquitin-conjugating enzymes which are critical for regulating the cell cycle. in Cytogenetics and cell genetics 1996 (PubMed)
    Show all 3 references for 387910

  4. Human Polyclonal UBE2I Primary Antibody for ICC, IF - ABIN268538 : Uemura, Taniguchi, Matsuo, Oku, Wakabayashi, Yoshida: UBC9 regulates the stability of XBP1, a key transcription factor controlling the ER stress response. in Cell structure and function 2013 (PubMed)
    Show all 2 references for 268538

  5. Human Monoclonal UBE2I Primary Antibody for ICC, FACS - ABIN969451 : Mohideen, Capili, Bilimoria, Yamada, Bonni, Lima: A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9. in Nature structural & molecular biology 2009 (PubMed)
    Show all 2 references for 969451

  6. Human Polyclonal UBE2I Primary Antibody for EIA, IHC (p) - ABIN356594 : Tachibana, Iwata, Watanabe, Nobukuni, Ploplis, Kajigaya: Assignment of the gene for a ubiquitin-conjugating enzyme (UBE2I) to human chromosome band 16p13.3 by in situ hybridization. in Cytogenetics and cell genetics 1997 (PubMed)
    Show all 2 references for 356594

  7. Human Polyclonal UBE2I Primary Antibody for IHC, ELISA - ABIN184894 : Wang, Qiu, Seufert, Taguchi, Testa, Whitmore, Callen, Welsh, Shenk, Deuel: Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9. in The Journal of biological chemistry 1996 (PubMed)

  8. Cow (Bovine) Polyclonal UBE2I Primary Antibody for WB - ABIN2775680 : Zhu, Zhang, Matunis: SUMO modification through rapamycin-mediated heterodimerization reveals a dual role for Ubc9 in targeting RanGAP1 to nuclear pore complexes. in Experimental cell research 2006 (PubMed)

  9. Cow (Bovine) Polyclonal UBE2I Primary Antibody for WB - ABIN2775681 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)

More Antibodies against Ubiquitin-Conjugating Enzyme E2I Interaction Partners

Pig (Porcine) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. Analysis of protein interactions showed that K179A, K180A, and K221A substitutions of classical swine fever virus core protein disrupt core-SUMO-1 (show SUMO1 Antibodies) binding, while K220A substitution precludes core-UBC9 binding.

Caenorhabditis elegans (C. elegans) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. TBX-2 (show TBX2 Antibodies) and SUMO-conjugating enzymes are necessary for ABa-derived pharyngeal muscle, and we hypothesize that TBX-2 (show TBX2 Antibodies) function requires sumoylation.

Human Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. Sumoylation of PML (show PML Antibodies) with SUMO2 (show SUMO2 Antibodies) by UBC9/UBE2I can lead to formation of polymeric SUMO chains. Data suggest that coordination of growing poly-SUMO chain with "back side" binding site on UBC9/UBE2I appears to be required for SUMO chain elongation on PML (show PML Antibodies). (PML (show PML Antibodies) = promyelocytic leukemia protein (show PML Antibodies); SUMO2 (show SUMO2 Antibodies) = small ubiquitin-like modifier 2 (show SUMO2 Antibodies); UBC9/UBE2I = ubiquitin-conjugating enzyme (show Ube2t Antibodies) UBC9/UBE2I)

  2. The role of Transthyretin (show TTR Antibodies) in the regulation of Ubc9 SUMOylation

  3. These findings point to UBC9 and autophagy as novel hallmarks of human papillomavirus oncogenesis

  4. These findings reveal that SUMO E1~E2 oxidation is an essential redox switch in oxidative stress.

  5. the mRNA and protein expression of Ubc9 are regulated by the microRNA miRNA-30a (miR (show MLXIP Antibodies)-30a) in human subcutaneous adipocytes.

  6. miR-30e in VSMCs exerted an anti-atherosclerosis effect via inhibiting proliferation and migration, and promoting apoptosis of VSMCs. More specifically, it was demonstrated that miR-30e exhibited these effects on VSMCs partially through targeting Ube2i and downregulating the IkappaBalpha/NFkappaB signaling pathway.

  7. Ubc9 plays different roles of action in antitumor agents in chemotherapy. The process requires bleomycin hydrolase (show BLMH Antibodies) and poly(ADP-ribose) polymerase-1 (show PARP1 Antibodies). The results are beneficial to deeply understanding of Ubc9 functions and for precise prediction of chemotherapy outcomes in tumors.

  8. Suggest a novel role of PCGF2 (show PCGF2 Antibodies) in arsenic trioxide-mediated degradation of PML (show PML Antibodies)-RARA (show RARA Antibodies) that PCGF2 (show PCGF2 Antibodies) might act as a negative regulator of UBE2I via direct interaction.

  9. Akt (show AKT1 Antibodies) directly phosphorylates Ubc9 at Thr35 and phosphorylates SUMO1 (show SUMO1 Antibodies) at Thr76. Ubc9 phosphorylation at Thr35 promotes Ubc9 thioester bond formation and SUMO1 (show SUMO1 Antibodies) phosphorylation at Thr76 stabilizes the SUMO1 (show SUMO1 Antibodies) protein.

  10. Characterization and Structural Insights into Selective E1-E2 Interactions in the Human and Plasmodium falciparum SUMO Conjugation Systems.

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. These findings suggest that the UBC9/PML/RNF4 axis plays a critical role as an important SUMO pathway in cardiac fibrosis. Modulating the protein levels of the pathway provides an attractive therapeutic target for the treatment of cardiac fibrosis and heart failure.

  2. this study shows that loss of Ubc9 results in a significant reduction of CD4 (show CD4 Antibodies) and CD8 (show CD8A Antibodies) single-positive lymphocytes in both thymus and periphery

  3. Increased UBC9-mediated SUMOylation is sufficient to upregulate cardiac autophagy. UBC9 overexpression reduced aggregate formation, decreased fibrosis, reduced hypertrophy, and improved cardiac function and survival.

  4. The study reveals a function of SUMO protein modification as a Ubiquitin-independent ESCRT sorting signal, regulating the extracellular vesicle release of alpha-Synuclein (show SNCA Antibodies).

  5. Synaptic trapping of Ubc9 through a PKC (show PKC Antibodies) phosphorylation-dependent increase of Ubc9 recognition to phosphorylated substrates and consequently leads to the modulation of synaptic sumoylation.

  6. UBC9 has a role in promoting proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis

  7. the sole SUMO E2 enzyme Ubc9 plays a critical role in reprogramming fibroblasts to iPS cells and maintaining ESC pluripotency.

  8. Data indicate that knockdown of ubiquitin-conjugating enzyme 9 (UBC9) by small interfering RNA caused significant accumulations of aggregated protein.

  9. Ubc9 negatively regulates osteoblastic differentiation induced by BMP.

  10. expressed Ubc9 at modestly increased levels showed robust resistance to brain ischemia compared to wild type mice

Zebrafish Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. These data indicate an in vivo requirement of Ubc9 for G2/M transition and/or progression through mitosis during vertebrate organogenesis.

Cow (Bovine) Ubiquitin-Conjugating Enzyme E2I (UBE2I) interaction partners

  1. Chromosomal assignment of the bovine ubiquitin-conjugating enzyme E2I (UBE2I ) gene to BTA6q34 defines a new fragment of conserved synteny with human chromosome 16.

Ubiquitin-Conjugating Enzyme E2I (UBE2I) Antigen Profile

Antigen Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with Ubiquitin-Conjugating Enzyme E2I (UBE2I)

  • ubiquitin-conjugating enzyme E2L (UBE2L) antibody
  • ubiquitin-conjugating enzyme E2I (LOC100358924) antibody
  • ubiquitin-conjugating enzyme E2I (UBE2I) antibody
  • Protein UBC-9 (ubc-9) antibody
  • ubiquitin conjugating enzyme 9 (UBC9) antibody
  • ubiquitin-conjugating enzyme E2I (Ube2i) antibody
  • ubiquitin-conjugating enzyme E2I (ube2i) antibody
  • 5830467E05Rik antibody
  • C358B7.1 antibody
  • F830028O17Rik antibody
  • P18 antibody
  • T13J8.70 antibody
  • T13J8_70 antibody
  • ubc9 antibody
  • UbcE2A antibody
  • Ubce2i antibody
  • ubce9 antibody
  • ube2ia antibody
  • ubiquitin conjugating enzyme 9 antibody
  • zUbc9 antibody

Protein level used designations for UBE2I

ubiquitin-conjugating enzyme E2L , ubiquitin-conjugating enzyme E2I , SUMO-conjugating enzyme UBC9 , SUMO-1 conjugating enzyme , ubiquitin conjugating enzyme 9 , ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) , SUMO-1-protein ligase , SUMO-protein ligase , ubiquitin carrier protein 9 , ubiquitin carrier protein I , ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9) , ubiquitin-conjugating enzyme UbcE2A , ubiquitin-like protein SUMO-1 conjugating enzyme , ubiquitin-protein ligase E2I , ubiquitin-protein ligase I , Ubiquitin conjugating enzyme E2I (homologous to yeast UBC9) , SUMO-conjugating enzyme UBC9-A , SUMO-protein ligase A , ubc9.1 , ubiquitin carrier protein 9-A , ubiquitin carrier protein I-A , ubiquitin-conjugating enzyme 9 , ubiquitin-conjugating enzyme E2 I-A , ubiquitin-protein ligase I-A , ubiquitin-conjugating enzyme E2I (UBC9 homolog) , ubiquitin-conjugating enzyme E2 I , Ubiquitin carrier protein 9 , Ubiquitin carrier protein I , Ubiquitin-conjugating enzyme E2 I , Ubiquitin-protein ligase I , ubiquitin conjugating enzyme

692788 Bombyx mori
100358924 Oryctolagus cuniculus
100533196 Sus scrofa
3565767 Caenorhabditis elegans
828909 Arabidopsis thaliana
7329 Homo sapiens
22196 Mus musculus
25573 Rattus norvegicus
30622 Danio rerio
380450 Xenopus laevis
374123 Gallus gallus
491332 Canis lupus familiaris
515573 Bos taurus
101843247 Mesocricetus auratus
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