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Human Polyclonal ZNF366 Primary Antibody for WB - ABIN2778520
Triantis, Trancikova, Looman, Hartgers, Janssen, Adema: Identification and characterization of DC-SCRIPT, a novel dendritic cell-expressed member of the zinc finger family of transcriptional regulators. in Journal of immunology (Baltimore, Md. : 1950) 2006
Human Polyclonal ZNF366 Primary Antibody for EIA, WB - ABIN955709
Lopez-Garcia, Periyasamy, Thomas, Christian, Leao, Jat, Kindle, Heery, Parker, Buluwela, Kamalati, Ali: ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases. in Nucleic acids research 2006
these data show that DC-SCRIPT acts as a novel regulator of CDKN2B (show CDKN2B Antibodies) and induces cell cycle arrest in ESR1 (show ESR1 Antibodies)-positive breast cancer cells.
DC-SCRIPT serves an important role in regulating GR function in DCs, corepressing GR-dependent upregulation of the tolerance-inducing transcription factor GILZ (show TSC22D3 Antibodies).
DC-SCRIPT is a key regulator of androgen receptor (show AR Antibodies) and vitamin d receptor (show VDR Antibodies) that play an opposite role in prostate cancer etiology and loss of DC-SCRIPT may be involved in the onset of prostate cancer.
DC-SCRIPT has a primary role in the regulation of interleukin (IL)-10 (show IL10 Antibodies) production by monocytes.
study provides a higher level of evidence that DC-SCRIPT is indeed an independent, pure prognostic, factor for primary breast cancer and shows that DC-SCRIPT mRNA expression is most informative for either ESR1 (show ESR1 Antibodies)-positive and/or ESR2 (show ESR2 Antibodies)-low pT1 (show ZNF77 Antibodies) tumors
Results indicate that ZNF366 may play an important role in regulating the expression of genes in response to estrogen.
Identification of ZNF366 and PTPRD (show PTPRD Antibodies) as novel determinants of plasma homocysteine in a family-based genome-wide association study
Has transcriptional repression activity. Acts as corepressor of ESR1\; the function seems to involve CTBP1 and histone deacetylases.