Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
antisaccade latencies were slower for HTR2A rs6313 C allele homozygotes than T allele carriers, with no effect of genotype on prosaccade latencies
There was no significant association between the 5-HT2A gene and schizophrenia or major depressive disorder
These data provide evidence that occupational stress and 5-HTR2A gene polymorphism contributes to the incidence of mental health problems.
Data provide evidence that work stressors, low social support, and 5-HTR2A gene polymorphism contributes to the risk of job strain.
Genetic loss of the 5-HT2A receptor compromised the activity of chronic treatment with selective serotonin reuptake inhibitors, making this receptor a putative marker to predict antidepressant response.
Report on the synthesis, microsomal stability, and 5-HT2A/5-HT2C receptor profile of novel analogues of 25B-NBOMe modified at the primary site of metabolism; important information about the structure-activity relationship of this compound class was obtained, especially the fact that the 5'-methoxy-substituent is not crucial for binding to and activation of the 5-HT2AR as previous investigations have suggested
Relative 5-HTR2A mRNA expression was significantly higher in PBMCs of all MDD patients when compared with healthy controls.
heterodimerization with 5-HT2C receptors does not alter 5-HT2C Galphaq-dependent inositol phosphate signaling, 5-HT2A or 5-HT2B receptor-mediated signaling was totally blunted. This feature can be explained by a dominance of 5-HT2C on 5-HT2A and 5-HT2B receptor binding; in 5-HT2C-containing heterodimers, ligands bind and activate the 5-HT2C protomer exclusively.
HTR2A minor variant of -1438 A/G (G-allele) predicts greater speed-dating success for men.
The HTR2A gene has been implicated as a major candidate for the serotonin disturbance seen in autism.
SMC (show DYM ELISA Kits)-rich intima as well as media directly contributes to the hypercontractile response of atherosclerotic vessels through the 5-HT(2A) receptor and the Rho-kinase (show ROCK1 ELISA Kits) pathway
we showed that gravity changes induced differential modulation of gene expression of BDNF (show BDNF ELISA Kits) and 5-HTRs (5-HT1AR, 5-HT1BR and 5-HT2AR) in some brain regions. The modulation of gene expression may constitute molecular bases that underlie behavioral alteration induced by gravity changes.
these data demonstrate that sustained SERT loss of function reduces 5-HT2AR surface expression that is critical for the synergistic activation of alphaIIbbeta3 by 5-HT and ADP.
In the present study we have demonstrated four new principal facts concerning the role of 5-HT2A receptors in thermoregulation
Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia.
Study showed that acute stress activates 5-HT2AR expression in the mouse cortex and this activation requires the immediate early (show JUN ELISA Kits) gene Egr3 (show EGR3 ELISA Kits)
Whole-brain mapping and pharmacological screening indicated that serotonin-2A receptor (Htr2a)-expressing cells in the central amygdala (CeA (show CEA ELISA Kits)) control both innate and learned freezing, but in opposing directions
Study showed increased expression in striatum membranes and decreased expression in frontal cortex membranes for both DRD2 (show DRD2 ELISA Kits) and Htr2a from heterozygous Reelin (show RELN ELISA Kits) mutant mice compared to wild-type
Hippocampal mRNA expression of Htr2a is decreased in serotonin deficient mice after early life stress.
Involvement of 5-HT2 receptors in the expression of withdrawal diarrhea in morphine-dependent mice
The 5-HT(2A) receptor subtype is sensitive to elevated stretch.
Early weaning results in less active behaviour, accompanied by lower 5-HT1A (show HTR1A ELISA Kits) and higher 5-HT2A receptor mRNA expression in specific brain regions.
excitatory 5-HT(2A) and inhibitory 5-HT(7) are present in the uterus of non-pregnant pigs. Endogenous 5-HT (show DDC ELISA Kits) containing cells are mainly present in uterine glands of the pig
According to the results obtained, no association between the analysed polymorphism of genes: 5HTR2A (T102C), SLC6A4 (5-HTTLPR (show SLC6A4 ELISA Kits)) and schizophrenia was found
5-HT(2) receptors are coupled to phospholipase C (show PLC ELISA Kits) in bovine ciliary epithelium.
analysis of eight bovine 5-HT receptor subtypes in brain, abomasum, and intestine by real-time RT-PCR
caveolar and cholesterol integrity are indispensable for the proper functionality of the H(1) and 5-HT(2A) receptors through their Rho/ROCK signaling.
Cimbi-36 is the first agonist radioligand suitable for examination of 5-HT2A receptors in the cortical regions and of 5-HT2C receptors in the choroid plexus of the primate brain.
found enrichment of serotonin receptor 2A mRNA in primary visual cortex (V1) and clear activity-dependent modulatory effects of 5-HT2A receptor agonists on responses of V1 neurons.
The 5-HT 2A receptor seem to be particularly involved in antigen-induced airway hyperresponsiveness(AI-AHR (show AHR ELISA Kits)) to ACh (show FGFR3 ELISA Kits) in guinea-pigs.
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
, 5-HT2 receptor
, 5-hydroxytryptamine receptor 2A
, serotonin 5-HT-2A receptor
, 5HT2A receptor
, serotonin receptor 2A
, 5-HT2a receptor
, 5-HT2A receptor
, 5-hydroxytryptamine 2 receptor
, serotonin 5HT-2 receptor
, 5-hydroxytryptamine (serotonin) receptor 2A
, serotonin 2 receptor