Browse our IFNA Proteins (IFNA)

Full name:
Interferon alpha Proteins (IFNA)
On are 54 Interferon alpha (IFNA) Proteins from 12 different suppliers available. Additionally we are shipping IFNA Antibodies (269) and IFNA Kits (161) and many more products for this protein. A total of 500 IFNA products are currently listed.
CAIFN-ALPHA 5, Ifa, Ifa1, Ifa8, IFL, IFL-1, IFN, IFN-a, IFN-ALPHA, IFN-ALPHA-1, IFN-alphaD, IFN-alphaI, IFN-gamma, IFN1@, IFNA, IFNA1, IFNA2, IFNA6, IFNA13, IFNA@, IL-28B, Il28, Il28b, INF-alpha, INF-lambda, INFA, LEIF2C1
list all proteins Gene Name GeneID UniProt
IFNA 15962 P01572
IFNA 3439 P01562

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IFNA Proteins (IFNA) by Origin

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Top referenced IFNA Proteins

  1. Human IFNA Protein expressed in Escherichia coli (E. coli) - ABIN666845 : Goeddel, Leung, Dull, Gross, Lawn, McCandliss, Seeburg, Ullrich, Yelverton, Gray: The structure of eight distinct cloned human leukocyte interferon cDNAs. in Nature 1981 (PubMed)
    Show all 3 references for 666845

  2. Human IFNA Protein expressed in Escherichia coli (E. coli) - ABIN413375 : Sen, Che, Rajamani, Zerboni, Sung, Ptacek, Arvin: Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)

  3. Human IFNA Protein expressed in Escherichia coli (E. coli) - ABIN803851 : Goetzl, Huang, Kon, Patel, Schwartz, Fast, Ferrucci, Madara, Taub, Longo: Gender specificity of altered human immune cytokine profiles in aging. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 (PubMed)

More Proteins for IFNA Interaction Partners

Cow (Bovine) Interferon alpha (IFNA) interaction partners

  1. Mutation of the IFNAR-1 (show IFNAR1 Proteins) receptor binding site of human IFN-alpha2 (show IFNA2 Proteins) generates type I IFN competitive antagonists.

  2. produced in vitro and in vivo in response to noncytopathic bovine viral diarrhea virus in lymph nodes cells expressing the myeloid markers CD14 (show CD14 Proteins), CD11b (show ITGAM Proteins), and CD172a (show SIRPA Proteins)

  3. Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 (show STAT1 Proteins) and, to a lesser extent, STAT2 (show STAT2 Proteins).

Mouse (Murine) Interferon alpha (IFNA) interaction partners

  1. These findings also identify STAT3 (show STAT3 Proteins) as a therapeutic target against viral infection and highlight it as an essential pathway component for endogenous and therapeutic IFN-alpha responsiveness.

  2. CD169 (show SIGLEC1 Proteins)(+) macrophages are important contributors to the IFN-I response and thereby influence antiviral activity, CD8 (show CD8A Proteins)(+) T-cell exhaustion and immunopathology.

  3. These results suggest that pulmonary C-fibers affect IFNGR1 (show IFNGR1 Proteins) expression by inducing IFN-alpha to regulate IFN-gamma (show IFNG Proteins)-mediated airway inflammation and airway hyperresponsiveness.

  4. results show that resistance to HSV-1 in the trigeminal ganglia during acute infection is conferred in part by STING and IFN-alpha/beta signaling in both bone marrow-derived and -resident cells, which coalesce to support a robust HSV-1-specific CD8 (show CD8A Proteins)(+) T cell response

  5. the close association between the increased proportion of CD180 (show CD180 Proteins)-negative B cells and the activation of IFN-alpha signaling in Systemic lupus erythematosus, is reported.

  6. STAT2 (show STAT2 Proteins) recruits USP18 (show USP18 Proteins) to the type I IFN receptor subunit IFNAR2 (show IFNAR2 Proteins) via its constitutive membrane-distal STAT2 (show STAT2 Proteins)-binding site.

  7. In the exorbital lachrymal gland, the mRNA expression of IFN beta and IFN alpha (type I IFNs) was weak- to strong-positive at 1 days post inoculation (DPI), and became negative at 2DPI.

  8. IRF-1 (show IRF1 Proteins) and interferon-alpha with interferon-beta (show IFNB1 Proteins) cooperate to control acute gammaherpesvirus infection.

  9. APOBEC3 can restrict retroviruses in a type I interferon-independent manner in vivo. By contrast, the ability of APOBEC3 to promote neutralizing antibody responses is type I interferon-dependent.

  10. IL-28B (show IL28B Proteins) down-regulates Tregs following subunit vaccine ESAT6-Ag85B-Mpt64(190-198)-Mtb8.4-HspX (show HSP Proteins) vaccination but does not improve the protective immune responses.

Pig (Porcine) Interferon alpha (IFNA) interaction partners

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon response by inducing STAT1 (show STAT1 Proteins) degradation.

  2. Amino acid residues in the N-terminal domain of Npro are involved in the stability of Npro, in interaction of Npro with IRF-3 (show IRF3 Proteins) and subsequent degradation of IRF-3 (show IRF3 Proteins), leading to downregulation of IFN-alpha/beta production.

  3. Pregnane X receptor is required for interferon-alpha-mediated CYP3A29 expression, and its expression before CYP3A29.

  4. Overall, data provide evidence for the possible role of PI3K in the activation of the transcription of IFN-alpha/beta by PRRSV; study concludes that PRRSV inhibits the induction of IFN-alpha in monocyte-derived dendritic cells by as yet undefined post-transcriptional mechanisms.

  5. Nsp1beta inhibits interferon-activated (show MNDA Proteins) STAT1 (show STAT1 Proteins)/STAT2 (show STAT2 Proteins) signal transduction by inducing karyopherin-alpha1 degradation.

  6. Expression of Mx protein (show MX2 Proteins) and interferon-alpha (IFN-alpha) was examined by immunohistochemistry in pigs experimentally infected with swine influenza virus.

  7. Foot-and-Mouth Disease Virus inhibits IFN-alpha expression in infected cells by blocking cap-dependent translation.

Human Interferon alpha (IFNA) interaction partners

  1. results demonstrate that Sphingosine 1-phosphate lyase (SPL (show SGPL1 Proteins)) is a host factor that augments type I IFN responses during influenza A virus infection; study delineates the relationship between IKKepsilon (show IKBKE Proteins) and SPL (show SGPL1 Proteins), which provides a mechanistic understanding of the pro-IFN activity of SPL (show SGPL1 Proteins)

  2. These data suggest that plasmacytoid dendritic cells producing IFN-alpha and IL-33 (show IL33 Proteins) play a pivotal role in the chronic fibro-inflammatory responses underlying murine autoimmune pancreatitis and human IgG4-related autoimmune pancreatitis.

  3. These findings also identify STAT3 (show STAT3 Proteins) as a therapeutic target against viral infection and highlight it as an essential pathway component for endogenous and therapeutic IFN-alpha responsiveness.

  4. Mothers of children affected by autoimmune congenital heart block had a significantly higher expression IFN-alpha.

  5. Suppression of the exogenous Type I IFN-induced Jak (show JAK3 Proteins)/STAT (show STAT1 Proteins) signaling by NSs might be one of the mechanisms of Severe fever with thrombocytopenia syndrome (SFTS) to evade host immune surveillance.

  6. High Type I Interferon expression due to hypomethylation is associated with Systemic Lupus Erythematosus.

  7. these studies identify phosphorylation of S734-STAT2 (show STAT2 Proteins) as a new regulatory mechanism that negatively controls the type I IFN-antiviral response.

  8. The synthetic IFNP molecule exerted its antitumor activity by upregulating the downstream genes involved in the STAT1 (show STAT1 Proteins) pathway and in apoptosis. Using a cell receptor binding assay, we showed that this Jurkat-binding peptide (show HP Proteins) facilitated the binding affinity of IFNalpha to the cell surface type I IFN receptor

  9. KSHV-encoded viral IRF4 (show IRF4 Proteins) interacts with the host IRF7 (show IRF7 Proteins) and inhibits interferon-alpha production.

  10. Data indicate ARID3a (show ARID3A Proteins)(+) B cells as a type of effector B cell, and link ARID3a (show ARID3A Proteins) expression in B lymphocytes to interferon alpha (IFNa)-associated inflammatory responses in systemic lupus erythematosus (SLE).

IFNA Protein Profile

Protein Summary

Produced by macrophages, IFN-alpha have antiviral protein kinase and an oligoadenylate synthetase.

Alternative names and synonyms associated with IFNA

  • interferon (IFNA3)
  • interferon (alpha, beta and omega) receptor 1 (IFNAR1)
  • interferon alpha (IFNA)
  • interferon alpha 1 (Ifna1)
  • Interferon alpha-1-like (LOC616272)
  • interferon alpha-A (IFNAA)
  • interferon lambda 3 (Ifnl3)
  • interferon-alpha (IFNA)
  • interferon, alpha 1 (IFNA1)
  • interferon, alpha 17 (IFNA17)
  • interferon, alpha 5 (IFNA5)
  • interferon, alpha 7 (IFNA7)
  • interferon alpha (Ifna)
  • CAIFN-ALPHA 5 protein
  • Ifa protein
  • Ifa1 protein
  • Ifa8 protein
  • IFL protein
  • IFL-1 protein
  • IFN protein
  • IFN-a protein
  • IFN-ALPHA protein
  • IFN-ALPHA-1 protein
  • IFN-alphaD protein
  • IFN-alphaI protein
  • IFN-gamma protein
  • IFN1@ protein
  • IFNA protein
  • IFNA1 protein
  • IFNA2 protein
  • IFNA6 protein
  • IFNA13 protein
  • IFNA@ protein
  • IL-28B protein
  • Il28 protein
  • Il28b protein
  • INF-alpha protein
  • INF-lambda protein
  • INFA protein
  • LEIF2C1 protein

Protein level used designations for Interferon alpha Proteins (IFNA)

IFN alpha , interferon alpha , interferon type A1/A2 , interferon type A3 , interferon-alpha , IFN-R-1 , IFN-alpha-REC , IFN-alpha/beta receptor 1 , interferon alpha/beta receptor 1 , interferon, alpha; receptor , interferon-alpha/beta receptor 1 , interferon-alpha/beta receptor alpha chain , type I interferon receptor 1 , IFN-alpha-1 , interferon alpha family gene 1 , interferon alpha-1 , interferon alpha A , IFN-lambda-3 , interferon lambda-3 , interleukin 28 , interleukin 28B , interleukin-28B , IFN-alpha-6 , interferon alpha 1 , interferon-alpha-6 , IFN-alpha 1b , IFN-alpha-1/13 , interferon alpha 1b , interferon alpha-1/13 , interferon alpha-D , interferon-alpha1 , leIF D , IFN-alpha-17 , interferon alpha-17 , interferon alpha-88 , interferon alpha-I' , interferon alpha-T , interferon alpha-WA , leIF I , IFN-alpha , interferon alpha 7

396398 Gallus gallus
282257 Bos taurus
100008635 Oryctolagus cuniculus
15962 Mus musculus
616272 Bos taurus
515951 Bos taurus
338374 Mus musculus
100860850 Capra hircus
397686 Sus scrofa
3439 Homo sapiens
3451 Homo sapiens
442934 Canis lupus familiaris
493653 Felis catus
111654 Mus musculus
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