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Browse our IFNA Proteins (IFNA)

Full name:
Interferon alpha Proteins (IFNA)
On are 53 Interferon alpha (IFNA) Proteins from 12 different suppliers available. Additionally we are shipping IFNA Antibodies (266) and IFNA Kits (158) and many more products for this protein. A total of 493 IFNA products are currently listed.
CAIFN-ALPHA 5, Ifa, Ifa1, Ifa8, IFL, IFL-1, IFN, IFN-a, IFN-ALPHA, IFN-ALPHA-1, IFN-alphaD, IFN-alphaI, IFN-gamma, IFN1@, IFNA, IFNA1, IFNA2, IFNA6, IFNA13, IFNA@, IL-28B, Il28, Il28b, INF-alpha, INF-lambda, INFA, LEIF2C1
list all proteins Gene Name GeneID UniProt
IFNA 15962 P01572
IFNA 3439 P01562

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IFNA Proteins (IFNA) by Origin

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Top referenced IFNA Proteins

  1. Human IFNA Protein expressed in Escherichia coli (E. coli) - ABIN666845 : Goeddel, Leung, Dull, Gross, Lawn, McCandliss, Seeburg, Ullrich, Yelverton, Gray: The structure of eight distinct cloned human leukocyte interferon cDNAs. in Nature 1981 (PubMed)
    Show all 3 references for ABIN666845

  2. Human IFNA Protein expressed in Escherichia coli (E. coli) - ABIN413375 : Sen, Che, Rajamani, Zerboni, Sung, Ptacek, Arvin: Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)

  3. Human IFNA Protein expressed in Escherichia coli (E. coli) - ABIN803851 : Goetzl, Huang, Kon, Patel, Schwartz, Fast, Ferrucci, Madara, Taub, Longo: Gender specificity of altered human immune cytokine profiles in aging. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 (PubMed)

More Proteins for IFNA Interaction Partners

Cow (Bovine) Interferon alpha (IFNA) interaction partners

  1. Mutation of the IFNAR-1 (show IFNAR1 Proteins) receptor binding site of human IFN-alpha2 (show IFNA2 Proteins) generates type I IFN competitive antagonists.

  2. produced in vitro and in vivo in response to noncytopathic bovine viral diarrhea virus in lymph nodes cells expressing the myeloid markers CD14 (show CD14 Proteins), CD11b (show ITGAM Proteins), and CD172a (show SIRPA Proteins)

  3. Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 (show STAT1 Proteins) and, to a lesser extent, STAT2 (show STAT2 Proteins).

Mouse (Murine) Interferon alpha (IFNA) interaction partners

  1. STAT2 (show STAT2 Proteins) recruits USP18 (show USP18 Proteins) to the type I IFN receptor subunit IFNAR2 (show IFNAR2 Proteins) via its constitutive membrane-distal STAT2 (show STAT2 Proteins)-binding site.

  2. In the exorbital lachrymal gland, the mRNA expression of IFN beta and IFN alpha (type I IFNs) was weak- to strong-positive at 1 days post inoculation (DPI), and became negative at 2DPI.

  3. IRF-1 (show IRF1 Proteins) and interferon-alpha with interferon-beta (show IFNB1 Proteins) cooperate to control acute gammaherpesvirus infection.

  4. APOBEC3 can restrict retroviruses in a type I interferon-independent manner in vivo. By contrast, the ability of APOBEC3 to promote neutralizing antibody responses is type I interferon-dependent.

  5. IL-28B (show IL28B Proteins) down-regulates Tregs following subunit vaccine ESAT6-Ag85B-Mpt64(190-198)-Mtb8.4-HspX (show HSP Proteins) vaccination but does not improve the protective immune responses.

  6. We concluded that the vulnerability of plaques was associated with the activation of IFN-I in pristane-treated ApoE (show APOE Proteins)(-/-) mice

  7. the role of IFN-lambda in IDO (show IDO1 Proteins) regulation was investigated after influenza infection of respiratory epithelial cells.

  8. Data show that decreased type I interferon gene expression in T cell subsets of human CASP8 (show CASP8 Proteins) and FADD (show FADD Proteins)-like apoptosis regulating protein c (show PROC Proteins)-FLIPS (show CFLAR Proteins) transgenic female mice.

  9. Data indicate that rotavirus infection induces production of interferon-lambda (IFN-lambda) and interleukin 22 (IL-22 (show IL22 Proteins)) by intestinal epithelial cells.

  10. TRIM13 (show TRIM13 Proteins) interacts with MDA5 (show IFIH1 Proteins) and negatively regulates MDA5 (show IFIH1 Proteins)-mediated type I IFN production.

Pig (Porcine) Interferon alpha (IFNA) interaction partners

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon response by inducing STAT1 (show STAT1 Proteins) degradation.

  2. Amino acid residues in the N-terminal domain of Npro are involved in the stability of Npro, in interaction of Npro with IRF-3 (show IRF3 Proteins) and subsequent degradation of IRF-3 (show IRF3 Proteins), leading to downregulation of IFN-alpha/beta production.

  3. Pregnane X receptor is required for interferon-alpha-mediated CYP3A29 expression, and its expression before CYP3A29.

  4. Overall, data provide evidence for the possible role of PI3K in the activation of the transcription of IFN-alpha/beta by PRRSV; study concludes that PRRSV inhibits the induction of IFN-alpha in monocyte-derived dendritic cells by as yet undefined post-transcriptional mechanisms.

  5. Nsp1beta inhibits interferon-activated (show MNDA Proteins) STAT1 (show STAT1 Proteins)/STAT2 (show STAT2 Proteins) signal transduction by inducing karyopherin-alpha1 degradation.

  6. Expression of Mx protein (show MX2 Proteins) and interferon-alpha (IFN-alpha) was examined by immunohistochemistry in pigs experimentally infected with swine influenza virus.

  7. Foot-and-Mouth Disease Virus inhibits IFN-alpha expression in infected cells by blocking cap-dependent translation.

Human Interferon alpha (IFNA) interaction partners

  1. KSHV-encoded viral IRF4 (show IRF4 Proteins) interacts with the host IRF7 (show IRF7 Proteins) and inhibits interferon-alpha production.

  2. Data indicate ARID3a (show ARID3A Proteins)(+) B cells as a type of effector B cell, and link ARID3a (show ARID3A Proteins) expression in B lymphocytes to interferon alpha (IFNa)-associated inflammatory responses in systemic lupus erythematosus (SLE).

  3. On one hand, hepatitis B virus activates MMP-9 (show MMP9 Proteins) in infected patients and leukocytes. On the other hand, MMP-9 (show MMP9 Proteins) facilitates hepatitis B virus replication through repressing IFN/JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins) signaling, IFNAR1 (show IFNAR1 Proteins) function, and IFN-alpha action.

  4. Interferon-alpha Induces the apoptosis of Hela cells by activating both the intrinsic mitochondrial pathway and endoplasmic reticulum stress-induced pathway.

  5. Decreased interferon alpha (IFN-alpha) secretion induced by Toll-like receptor 7 (show TLR7 Proteins) and Toll-like receptor 8 (show TLR8 Proteins) (TLR7 (show TLR7 Proteins)/TLR8 (show TLR8 Proteins)) activation was observed in common variable immunodeficiency (CVID (show TNFRSF13B Proteins)), which was recovered with Toll-like receptor 9 (TLR9 (show TLR9 Proteins)) signaling.

  6. Plasmacytoid dendritic cells (pDCs) and type 1 interferon (FNalpha/beta)frequently accompanied plasmablast/plasma cells (PB/PCs).

  7. These results establish that activation of STAT (show STAT1 Proteins) pathway is essential for anti-hepatitis c virus efficacy of IFN-alpha.

  8. IL-2 (show IL2 Proteins) therapy should be used as a first- or second-line therapy following IFN-a (show IFNA6 Proteins) therapy. IL-2 (show IL2 Proteins) may have a lower response if it is used after molecular-targeted therapy or other treatments

  9. results show that IFNA1 (show IFNA1 Proteins) rs1332190 and IFNA17 (show IFNa17 Proteins) rs9298814 SNPs may play an important role in Crimean-Congo hemorrhagic fever susceptibility

  10. Interferon-alpha-induced TRIM22 (show TRIM22 Proteins) interrupts hepatitis c virus replication by ubiquitinating NS5A.

IFNA Protein Profile

Protein Summary

Produced by macrophages, IFN-alpha have antiviral protein kinase and an oligoadenylate synthetase.

Alternative names and synonyms associated with IFNA

  • interferon (IFNA3)
  • interferon (alpha, beta and omega) receptor 1 (IFNAR1)
  • interferon alpha (IFNA)
  • interferon alpha 1 (Ifna1)
  • Interferon alpha-1-like (LOC616272)
  • interferon alpha-A (IFNAA)
  • interferon lambda 3 (Ifnl3)
  • interferon-alpha (IFNA)
  • interferon, alpha 1 (IFNA1)
  • interferon, alpha 17 (IFNA17)
  • interferon, alpha 5 (IFNA5)
  • interferon, alpha 7 (IFNA7)
  • interferon alpha (Ifna)
  • CAIFN-ALPHA 5 protein
  • Ifa protein
  • Ifa1 protein
  • Ifa8 protein
  • IFL protein
  • IFL-1 protein
  • IFN protein
  • IFN-a protein
  • IFN-ALPHA protein
  • IFN-ALPHA-1 protein
  • IFN-alphaD protein
  • IFN-alphaI protein
  • IFN-gamma protein
  • IFN1@ protein
  • IFNA protein
  • IFNA1 protein
  • IFNA2 protein
  • IFNA6 protein
  • IFNA13 protein
  • IFNA@ protein
  • IL-28B protein
  • Il28 protein
  • Il28b protein
  • INF-alpha protein
  • INF-lambda protein
  • INFA protein
  • LEIF2C1 protein

Protein level used designations for Interferon alpha Proteins (IFNA)

IFN alpha , interferon alpha , interferon type A1/A2 , interferon type A3 , interferon-alpha , IFN-R-1 , IFN-alpha-REC , IFN-alpha/beta receptor 1 , interferon alpha/beta receptor 1 , interferon, alpha; receptor , interferon-alpha/beta receptor 1 , interferon-alpha/beta receptor alpha chain , type I interferon receptor 1 , IFN-alpha-1 , interferon alpha family gene 1 , interferon alpha-1 , interferon alpha A , IFN-lambda-3 , interferon lambda-3 , interleukin 28 , interleukin 28B , interleukin-28B , IFN-alpha-6 , interferon alpha 1 , interferon-alpha-6 , IFN-alpha 1b , IFN-alpha-1/13 , interferon alpha 1b , interferon alpha-1/13 , interferon alpha-D , interferon-alpha1 , leIF D , IFN-alpha-17 , interferon alpha-17 , interferon alpha-88 , interferon alpha-I' , interferon alpha-T , interferon alpha-WA , leIF I , IFN-alpha , interferon alpha 7

396398 Gallus gallus
282257 Bos taurus
100008635 Oryctolagus cuniculus
15962 Mus musculus
616272 Bos taurus
515951 Bos taurus
338374 Mus musculus
100860850 Capra hircus
397686 Sus scrofa
3439 Homo sapiens
3451 Homo sapiens
442934 Canis lupus familiaris
493653 Felis catus
111654 Mus musculus
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