Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Cynomolgus IFNA8 Protein expressed in Human Cells - ABIN2009855
Henco, Brosius, Fujisawa, Fujisawa, Haynes, Hochstadt, Kovacic, Pasek, Schamböck, Schmid: Structural relationship of human interferon alpha genes and pseudogenes. in Journal of molecular biology 1985
These data suggest that increased IFN-alpha8 (show IFNa14 Proteins) activity may promote the loss of T cells by accelerating cell turnover and activation-induced cell death while decreasing the renewal of T cells by inhibiting the proliferative effect of IL-7 (show IL7 Proteins).
IFN-alpha8 (show IFNa14 Proteins) and -alpha10 most potently enhanced expression of IFN-gamma (show IFNG Proteins), IL-2 (show IL2 Proteins), and IL-4 (show IL4 Proteins).
variation at IFNA2 (show IFNA2 Proteins) -173 and IFNA8 -884 conditions reduced IFN-alpha (show IFNA Proteins) production, and increased susceptibility to SMA (show SMN1 Proteins) and mortality
Data describe the species specificity of IFN-alphas, the residues in murine IFN-alpha4 that preclude strong affinity interactions with human IFNAR1 (show IFNAR1 Proteins) and 2, and residues in human IFN-alpha8 (show IFNa14 Proteins) that resemble a receptor interactive domain in murine IFN-alpha4.
Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.
Produced by macrophages, IFN-alpha have antiviral protein kinase and an oligoadenylate synthetase.
, interferon alpha type 201
, interferon alpha-8
, interferon alpha-B
, interferon alpha-B'
, interferon alpha-B2
, leIF B
, interferon, alpha 8
, IFN-alpha B