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Browse our IFNB1 Proteins (IFNB1)

Full name:
Interferon, beta 1, Fibroblast Proteins (IFNB1)
On are 63 Interferon, beta 1, Fibroblast (IFNB1) Proteins from 15 different suppliers available. Additionally we are shipping IFNB1 Antibodies (381) and IFNB1 Kits (91) and many more products for this protein. A total of 550 IFNB1 products are currently listed.
list all proteins Gene Name GeneID UniProt
IFNB1 15977 P01575
IFNB1 24481 P70499
IFNB1 3456 P01574

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IFNB1 Proteins (IFNB1) by Origin

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Top referenced IFNB1 Proteins

  1. Human IFNB1 Protein expressed in Human Cells - ABIN2003282 : Takaoka, Hayakawa, Yanai, Stoiber, Negishi, Kikuchi, Sasaki, Imai, Shibue, Honda, Taniguchi: Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. in Nature 2003 (PubMed)
    Show all 4 references for ABIN2003282

  2. Human IFNB1 Protein expressed in CHO Cells - ABIN2003285 : Improta, Pine: Susceptibility to virus infection is determined by a Stat-mediated response to the autocrine effect of virus-induced type I interferon. in Cytokine 1997 (PubMed)
    Show all 4 references for ABIN2003285

  3. Mouse (Murine) IFNB1 Protein expressed in HEK-293 - ABIN2666971 : Nagarajan: Induction and function of IFNβ during viral and bacterial infection. in Critical reviews in immunology 2012 (PubMed)
    Show all 3 references for ABIN2666971

  4. Mouse (Murine) IFNB1 Protein expressed in Escherichia coli (E. coli) - ABIN666768 : Fierlbeck, dHoedt, Stroebel, Stutte, Bogenschütz, Rassner: [Intralesional therapy of melanoma metastases with recombinant interferon-beta]. in Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1992 (PubMed)
    Show all 2 references for ABIN666768

  5. Human IFNB1 Protein expressed in Escherichia coli (E. coli) - ABIN1047212 : Lawn, Adelman, Franke, Houck, Gross, Najarian, Goeddel: Human fibroblast interferon gene lacks introns. in Nucleic acids research 1981 (PubMed)
    Show all 2 references for ABIN1047212

  6. Mouse (Murine) IFNB1 Protein expressed in Human Cells - ABIN2008198 : Biron, Nguyen, Pien: Innate immune responses to LCMV infections: natural killer cells and cytokines. in Current topics in microbiology and immunology 2002 (PubMed)

More Proteins for IFNB1 Interaction Partners

Rhesus Monkey Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. either JC1 or DS1 C/EBP site is sufficient to mediate IFN beta-induced down-regulation of SIV long terminal repeat activity and virus replication in macrophages

  2. Hepatitis A virus protein 2B suppresses beta interferon (show IFNA Proteins) (IFN) gene transcription by interfering with IFN regulatory factor 3 activation.

Cow (Bovine) Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. The data confirm the involvement of EHMT2 (show EHMT2 Proteins) in the epigenetic regulation of IFN-b and demonstrate the activation of a general antiviral state after EHMT2 (show EHMT2 Proteins) inhibition.

  2. The authors provide evidence that ICP27 protein encoded by bovine herpesvirus type 1, a viral early protein that shuttles between the nucleus and cytoplasm inhibits transcriptional activity of two bovine IFN-beta gene promoters (IFN-beta1 and IFN-beta3).

  3. The authors demonstrate that bovine herpesvirus 1 bICP0 effectively inhibits bovine IFN-beta promoter activity and induces IRF3 (show IRF3 Proteins) degradation.

  4. These studies provide evidence that virus infection differentially stimulates expression of the three bovine IFN-beta genes.

  5. recombinant bovine respiratory syncytial virus lacking the NS proteins, and those lacking NS2 in particular, are strong inducers of IFN-alpha (show IFNA Proteins)/beta in bovine nasal fibroblasts and bronchoalveolar macrophages.

Mouse (Murine) Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. identify iNOS (show NOS2 Proteins)/NO as an integral component of IFN-beta production in response to dsRNA in hepatocytes in a pathway that involves the coordinated activities of TLR3 (show TLR3 Proteins)/Trif (show RNF138 Proteins) and PKR (show EIF2AK2 Proteins)

  2. Data show that using adipose-derived mesenchymal stem cells (AD-MSCs) expressing interferon-beta (IFN-beta) as an anti-inflammatory agent, offer evidence supporting that the stem cell therapies in experimental autoimmune encephalomyelitis (EAE) may improve the valuable effects of IFN-beta in the autoimmune disease.

  3. NLRX1 was observed to reduce interferon beta and cytokines in response to HIV-1 reverse-transcribed DNA.

  4. This study establishes IL-1beta (show IL1B Proteins) and IFN-I levels as key homeostatic variables of protective, yet tuned, immune responses against severe invasive bacterial infection.

  5. Data indicate the cyclin-dependent kinase inhibitor 2A (p19Arf) and interferon beta (IFN-beta) combination as a cancer immunotherapy strategy.

  6. Results suggest that the lack of autocrine response to interferon (show IFNA Proteins)-betaI by the host cell may be one mechanism for maintenance of respiratory syncytial virus persistence.

  7. TRIM33 (show TRIM33 Proteins) deficiency results in high expression of Ifnb1 at late stages of macrophages activation.

  8. Inhibition of PI3K or Akt (show AKT1 Proteins) abrogated the ability of Syk (show SYK Proteins) deficiency to enhance IFNbeta and IL-10 (show IL10 Proteins) in Syk (show SYK Proteins) deficient cells

  9. Enhancement of the constitutive level of IFN-beta per se was able to confer an efficient antiviral state to naive cells and acted in synergy with virus infection to stimulate virus-induced IFN-beta expression

  10. Data show that activating transcription factor 3 (ATF3 (show ATF3 Proteins)) acted as a transcriptional repressor and regulated interferon-beta (IFN-beta) via direct binding to a regulatory site distal to the Ifnb1 promoter.

Human Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. RNAs isolated from HCV-replicating cells triggered robust IFN-beta and IFN-lambda production through MDA5 (show IFIH1 Proteins).

  2. Plasmacytoid dendritic cells (pDCs) and type 1 interferon (show IFNA Proteins) (FNalpha/beta)frequently accompanied plasmablast/plasma cells (PB/PCs).

  3. These results suggest that inhibition of RIG-I (show DDX58 Proteins)-mediated type I interferon (show IFNA Proteins) responses by Enterovirus 71 may contribute to the pathogenesis of viral infection.

  4. the interactions of IRF1 (show IRF1 Proteins), IFN-beta and IRF5 (show IRF5 Proteins) are involved in the M1 polarization of macrophages and have antitumor functions.

  5. Data suggest that interferon beta (IFN-beta) might be involved in modulating the expressions of interferon regulatory factor 1 (IRF1 (show IRF1 Proteins)) and interferon regulatory factor-5 (show IRF5 Proteins) protein (IRF5 (show IRF5 Proteins)) as well as maintaining the M1 polarization status and its function.

  6. Results suggest that serum levels of IFN-beta do not correlate well with the severity of dengue illness, but there is a clear association between changes in IFN-beta levels and the days of evolution during the acute phase of the disease.

  7. Overexpression of KLF4 (show KLF4 Proteins) inhibited virus-induced activation of ISRE and IFN-b promoter in cells, while knockdown of KLF4 (show KLF4 Proteins) potentiated viral infection-triggered induction of IFNB1 and downstream genes and attenuated viral replication.

  8. These findings suggest that RNF166 positively regulates RNA virus-triggered IFN-beta production by enhancing the ubiquitination of TRAF3 (show TRAF3 Proteins) and TRAF6 (show TRAF6 Proteins).

  9. the suppression of type I IFN production by HTLV-1 Tax (show CNTN2 Proteins) through interaction with and inhibition of TBK1 (show TBK1 Proteins) kinase that phosphorylates IRF3 (show IRF3 Proteins)

  10. These results demonstrate that poliovirus infection actively suppresses the host type I interferon (show IFNA Proteins) response by blocking activation of IRF-3 (show IRF3 Proteins) and suggests that this is not mediated by cleavage of MDA-5 (show IFIH1 Proteins) or IPS-1 (show MAVS Proteins).

Pig (Porcine) Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. Highly pathogenic Porcine reproductive and respiratory syndrome virus modulates Interferon-beta expression mainly through attenuating IRF-3 (show IRF3 Proteins) phosphorylation.

  2. Porcine epidemic diarrhea virus nsp1 inhibited the IFN-beta and IRF3 (show IRF3 Proteins) promoter activities.

  3. poIFIT3 plays a significant role in the clearance of swine influenza virus in pigs and potentiates IFN-beta production.

  4. DDX41 (show DDX41 Proteins) is involved in the dsDNA- and dsDNA-virus-mediated type IFN-beta signaling pathway in porcine kidney cells.

  5. VIral NS4 (show SOS1 Proteins) protein antagonizes beta interferon (show IFNA Proteins) expression by targeting the NF-kappaB (show NFKB1 Proteins) essential modulator.

  6. Swine IFN-beta promotes genetic mutation of porcine reproductive and respiratory syndrome virus.

  7. Expression of LSm14A (show LSM14A Proteins) in HEK293 or Marc (show CCL7 Proteins)-145 cells enhanced activities of IFN-beta and NF-kappaB (show NFKB1 Proteins) promoters, induced IFN-beta transcription, and potentiated IFN-beta promoter activation, indicating that LSm14A (show LSM14A Proteins) is a potential signal molecule (show WNT4 Proteins) in the IFN-beta pathway.

  8. Overall, data provide evidence for the possible role of PI3K in the activation of the transcription of IFN-alpha (show IFNA Proteins)/beta by PRRSV; study concludes that PRRSV inhibits the induction of IFN-alpha (show IFNA Proteins) in monocyte-derived dendritic cells by as yet undefined post-transcriptional mechanisms.

IFNB1 Protein Profile

Protein Summary

suppresses the growth of rat glioma cells

Alternative names and synonyms associated with IFNB1

  • interferon, beta 1, fibroblast (IFNB1)
  • interferon, beta 1, fibroblast (LOC100342931)
  • interferon (alpha, beta and omega) receptor 2 (IFNAR2)
  • interferon beta 1, fibroblast (Ifnb1)
  • interferon, beta 1, fibroblast (IFNB)
  • IFB protein
  • IFF protein
  • IFN-beta protein
  • IFN-R protein
  • IFN-R-2 protein
  • IFNb protein
  • IFNBR protein

Protein level used designations for IFNB1

interferon beta , interferon beta 1 , interferon, beta 1, fibroblast , IFN-alpha-REC , IFN-alpha/beta receptor 2 , interferon alpha/beta receptor 2 , interferon, beta; receptor , interferon-alpha/beta receptor 2 , interferon-alpha/beta receptor beta chain , type I interferon receptor 2 , IFN-beta , interferon, beta 1 , fibroblast interferon , interferon type B , interferon-beta , interferon beta-1

711414 Macaca mulatta
100342931 Oryctolagus cuniculus
282258 Bos taurus
15977 Mus musculus
24481 Rattus norvegicus
3456 Homo sapiens
554219 Gallus gallus
445459 Sus scrofa
493849 Felis catus
100052545 Equus caballus
481558 Canis lupus familiaris
281845 Bos taurus
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