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Browse our IFNB1 Proteins (IFNB1)

Full name:
Interferon, beta 1, Fibroblast Proteins (IFNB1)
On www.antibodies-online.com are 61 Interferon, beta 1, Fibroblast (IFNB1) Proteins from 16 different suppliers available. Additionally we are shipping IFNB1 Antibodies (306) and IFNB1 Kits (82) and many more products for this protein. A total of 464 IFNB1 products are currently listed.
Synonyms:
IFB, IFF, IFN-beta, IFN-R, IFN-R-2, IFNb, IFNBR
list all proteins Gene Name GeneID UniProt
IFNB1 15977 P01575
IFNB1 24481 P70499
IFNB1 3456 P01574

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IFNB1 Proteins (IFNB1) by Origin

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Top referenced IFNB1 Proteins

  1. Human IFNB1 Protein expressed in Human Cells - ABIN2003282 : Takaoka, Hayakawa, Yanai, Stoiber, Negishi, Kikuchi, Sasaki, Imai, Shibue, Honda, Taniguchi: Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. in Nature 2003 (PubMed)
    Show all 4 references for ABIN2003282

  2. Human IFNB1 Protein expressed in CHO Cells - ABIN2003285 : Improta, Pine: Susceptibility to virus infection is determined by a Stat-mediated response to the autocrine effect of virus-induced type I interferon. in Cytokine 1997 (PubMed)
    Show all 4 references for ABIN2003285

  3. Mouse (Murine) IFNB1 Protein expressed in HEK-293 - ABIN2666971 : Nagarajan: Induction and function of IFNβ during viral and bacterial infection. in Critical reviews in immunology 2012 (PubMed)
    Show all 3 references for ABIN2666971

  4. Mouse (Murine) IFNB1 Protein expressed in Escherichia coli (E. coli) - ABIN666768 : Fierlbeck, dHoedt, Stroebel, Stutte, Bogenschütz, Rassner: [Intralesional therapy of melanoma metastases with recombinant interferon-beta]. in Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1992 (PubMed)
    Show all 2 references for ABIN666768

  5. Human IFNB1 Protein expressed in Escherichia coli (E. coli) - ABIN1047212 : Lawn, Adelman, Franke, Houck, Gross, Najarian, Goeddel: Human fibroblast interferon gene lacks introns. in Nucleic acids research 1981 (PubMed)
    Show all 2 references for ABIN1047212

  6. Mouse (Murine) IFNB1 Protein expressed in Human Cells - ABIN2008198 : Biron, Nguyen, Pien: Innate immune responses to LCMV infections: natural killer cells and cytokines. in Current topics in microbiology and immunology 2002 (PubMed)

More Proteins for IFNB1 Interaction Partners

Rhesus Monkey Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. either JC1 or DS1 C/EBP site is sufficient to mediate IFN beta-induced down-regulation of SIV long terminal repeat activity and virus replication in macrophages

  2. Hepatitis A virus protein 2B suppresses beta interferon (show IFNA Proteins) (IFN) gene transcription by interfering with IFN regulatory factor 3 activation.

Cow (Bovine) Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. The data confirm the involvement of EHMT2 (show EHMT2 Proteins) in the epigenetic regulation of IFN-b and demonstrate the activation of a general antiviral state after EHMT2 (show EHMT2 Proteins) inhibition.

  2. The authors provide evidence that ICP27 protein encoded by bovine herpesvirus type 1, a viral early protein that shuttles between the nucleus and cytoplasm inhibits transcriptional activity of two bovine IFN-beta gene promoters (IFN-beta1 and IFN-beta3).

  3. The authors demonstrate that bovine herpesvirus 1 bICP0 effectively inhibits bovine IFN-beta promoter activity and induces IRF3 (show IRF3 Proteins) degradation.

  4. These studies provide evidence that virus infection differentially stimulates expression of the three bovine IFN-beta genes.

  5. recombinant bovine respiratory syncytial virus lacking the NS proteins, and those lacking NS2 in particular, are strong inducers of IFN-alpha (show IFNA Proteins)/beta in bovine nasal fibroblasts and bronchoalveolar macrophages.

Mouse (Murine) Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. Data indicate the cyclin-dependent kinase inhibitor 2A (p19Arf) and interferon beta (IFN-beta) combination as a cancer immunotherapy strategy.

  2. Results suggest that the lack of autocrine response to interferon (show IFNA Proteins)-betaI by the host cell may be one mechanism for maintenance of respiratory syncytial virus persistence.

  3. TRIM33 (show TRIM33 Proteins) deficiency results in high expression of Ifnb1 at late stages of macrophages activation.

  4. Inhibition of PI3K or Akt (show AKT1 Proteins) abrogated the ability of Syk (show SYK Proteins) deficiency to enhance IFNbeta and IL-10 (show IL10 Proteins) in Syk (show SYK Proteins) deficient cells

  5. Enhancement of the constitutive level of IFN-beta per se was able to confer an efficient antiviral state to naive cells and acted in synergy with virus infection to stimulate virus-induced IFN-beta expression

  6. Data show that activating transcription factor 3 (ATF3 (show ATF3 Proteins)) acted as a transcriptional repressor and regulated interferon-beta (IFN-beta) via direct binding to a regulatory site distal to the Ifnb1 promoter.

  7. IFN-beta significantly attenuated the progression of liver fibrosis, with accompanying transcriptional downregulation of the TLR4 (show TLR4 Proteins) adaptor molecule MyD88 (show MYD88 Proteins).

  8. Mice lacking Ifnb function exhibited motor and cognitive learning impairments with accompanying alpha-synuclein-containing Lewy bodies in the brain, as well as a reduction in dopaminergic neurons and defective dopamine signaling in the nigrostriatal region.

  9. Data show that interferon beta knockout IFN-beta(-/-) mice exhibit greater resistance to Salmonella typhimurium infection.

  10. results indicate that Lyn (show LYN Proteins) plays a positive regulatory role in RIG-I (show DDX58 Proteins)-mediated interferon (show IFNA Proteins) expression as a downstream component of IPS-1 (show ISYNA1 Proteins)

Human Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. Overexpression of KLF4 (show KLF4 Proteins) inhibited virus-induced activation of ISRE and IFN-b promoter in cells, while knockdown of KLF4 (show KLF4 Proteins) potentiated viral infection-triggered induction of IFNB1 and downstream genes and attenuated viral replication.

  2. These findings suggest that RNF166 positively regulates RNA virus-triggered IFN-beta production by enhancing the ubiquitination of TRAF3 (show TRAF3 Proteins) and TRAF6 (show TRAF6 Proteins).

  3. the suppression of type I IFN production by HTLV-1 Tax (show CNTN2 Proteins) through interaction with and inhibition of TBK1 (show TBK1 Proteins) kinase that phosphorylates IRF3 (show IRF3 Proteins)

  4. These results demonstrate that poliovirus infection actively suppresses the host type I interferon (show IFNA Proteins) response by blocking activation of IRF-3 (show IRF3 Proteins) and suggests that this is not mediated by cleavage of MDA-5 (show IFIH1 Proteins) or IPS-1 (show MAVS Proteins).

  5. Together, the data demonstrate that interferon-beta inhibits foamy virus early in infection and that MxB is not a restriction factor of foamy virus.

  6. The C-terminal region of Toscana Virus NSs protein is critical for interferon-beta antagonism and protein stability.

  7. These findings support a model in which a measles virus defective interfering RNA is sensed by PACT (show RBBP6 Proteins) and RIG-I (show DDX58 Proteins) to initiate an innate antiviral response via activation of interferon-beta production.

  8. NS of severe fever with thrombocytopenia syndrome virus inhibited the activity of IFN-alpha1 (show IFNA1 Proteins), IFN-beta, IFN-lambda1 and IFN-lambda2 (show IL28A Proteins) through inhibition of STAT1 (show STAT1 Proteins) phosphorylation.

  9. Data suggest microRNA-302c regulates interferon-beta production in innate/mucosal immunity partly via down-regulation of interferon (show IFNA Proteins) regulatory factors IRF3 (show IRF3 Proteins)/7; studies were conducted in lung epithelial cells infected with influenza A virus H3N2.

  10. Data show that the MAPKKK6 ASK2 (show MAP3K6 Proteins), a modulator of MAPKKK5 ASK1 (show MAP3K5 Proteins) signaling, was essential for ASK1 (show MAP3K5 Proteins)-dependent apoptosis, but not for inducing interferon-beta (IFNB) expression.

Pig (Porcine) Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. Porcine epidemic diarrhea virus nsp1 inhibited the IFN-beta and IRF3 (show IRF3 Proteins) promoter activities.

  2. poIFIT3 plays a significant role in the clearance of swine influenza virus in pigs and potentiates IFN-beta production.

  3. DDX41 (show DDX41 Proteins) is involved in the dsDNA- and dsDNA-virus-mediated type IFN-beta signaling pathway in porcine kidney cells.

  4. VIral NS4 (show SOS1 Proteins) protein antagonizes beta interferon (show IFNA Proteins) expression by targeting the NF-kappaB (show NFKB1 Proteins) essential modulator.

  5. Swine IFN-beta promotes genetic mutation of porcine reproductive and respiratory syndrome virus.

  6. Expression of LSm14A (show LSM14A Proteins) in HEK293 or Marc (show CCL7 Proteins)-145 cells enhanced activities of IFN-beta and NF-kappaB (show NFKB1 Proteins) promoters, induced IFN-beta transcription, and potentiated IFN-beta promoter activation, indicating that LSm14A (show LSM14A Proteins) is a potential signal molecule (show WNT4 Proteins) in the IFN-beta pathway.

  7. Overall, data provide evidence for the possible role of PI3K in the activation of the transcription of IFN-alpha (show IFNA Proteins)/beta by PRRSV; study concludes that PRRSV inhibits the induction of IFN-alpha (show IFNA Proteins) in monocyte-derived dendritic cells by as yet undefined post-transcriptional mechanisms.

IFNB1 Protein Profile

Protein Summary

suppresses the growth of rat glioma cells

Alternative names and synonyms associated with IFNB1

  • interferon, beta 1, fibroblast (IFNB1)
  • interferon, beta 1, fibroblast (LOC100342931)
  • interferon (alpha, beta and omega) receptor 2 (IFNAR2)
  • interferon beta 1, fibroblast (Ifnb1)
  • interferon, beta 1, fibroblast (IFNB)
  • IFB protein
  • IFF protein
  • IFN-beta protein
  • IFN-R protein
  • IFN-R-2 protein
  • IFNb protein
  • IFNBR protein

Protein level used designations for IFNB1

interferon beta , interferon beta 1 , interferon, beta 1, fibroblast , IFN-alpha-REC , IFN-alpha/beta receptor 2 , interferon alpha/beta receptor 2 , interferon, beta; receptor , interferon-alpha/beta receptor 2 , interferon-alpha/beta receptor beta chain , type I interferon receptor 2 , IFN-beta , interferon, beta 1 , fibroblast interferon , interferon type B , interferon-beta , interferon beta-1

GENE ID SPECIES
711414 Macaca mulatta
100342931 Oryctolagus cuniculus
282258 Bos taurus
15977 Mus musculus
24481 Rattus norvegicus
3456 Homo sapiens
554219 Gallus gallus
445459 Sus scrofa
493849 Felis catus
100052545 Equus caballus
481558 Canis lupus familiaris
281845 Bos taurus
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