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Browse our IFNB1 Proteins (IFNB1)

Full name:
Interferon, beta 1, Fibroblast Proteins (IFNB1)
On are 61 Interferon, beta 1, Fibroblast (IFNB1) Proteins from 15 different suppliers available. Additionally we are shipping IFNB1 Antibodies (367) and IFNB1 Kits (97) and many more products for this protein. A total of 540 IFNB1 products are currently listed.
list all proteins Gene Name GeneID UniProt
IFNB1 15977 P01575
IFNB1 24481 P70499
IFNB1 3456 P01574

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IFNB1 Proteins (IFNB1) by Origin

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Top referenced IFNB1 Proteins

  1. Human IFNB1 Protein expressed in Human Cells - ABIN2003282 : Takaoka, Hayakawa, Yanai, Stoiber, Negishi, Kikuchi, Sasaki, Imai, Shibue, Honda, Taniguchi: Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. in Nature 2003 (PubMed)
    Show all 4 references for ABIN2003282

  2. Human IFNB1 Protein expressed in CHO Cells - ABIN2003285 : Improta, Pine: Susceptibility to virus infection is determined by a Stat-mediated response to the autocrine effect of virus-induced type I interferon. in Cytokine 1997 (PubMed)
    Show all 4 references for ABIN2003285

  3. Mouse (Murine) IFNB1 Protein expressed in HEK-293 - ABIN2666971 : Nagarajan: Induction and function of IFNβ during viral and bacterial infection. in Critical reviews in immunology 2012 (PubMed)
    Show all 3 references for ABIN2666971

  4. Mouse (Murine) IFNB1 Protein expressed in Escherichia coli (E. coli) - ABIN666768 : Fierlbeck, dHoedt, Stroebel, Stutte, Bogenschütz, Rassner: [Intralesional therapy of melanoma metastases with recombinant interferon-beta]. in Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1992 (PubMed)
    Show all 2 references for ABIN666768

  5. Human IFNB1 Protein expressed in Escherichia coli (E. coli) - ABIN1047212 : Lawn, Adelman, Franke, Houck, Gross, Najarian, Goeddel: Human fibroblast interferon gene lacks introns. in Nucleic acids research 1981 (PubMed)
    Show all 2 references for ABIN1047212

  6. Mouse (Murine) IFNB1 Protein expressed in Human Cells - ABIN2008198 : Biron, Nguyen, Pien: Innate immune responses to LCMV infections: natural killer cells and cytokines. in Current topics in microbiology and immunology 2002 (PubMed)

More Proteins for IFNB1 Interaction Partners

Rhesus Monkey Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. either JC1 or DS1 C/EBP site is sufficient to mediate IFN beta-induced down-regulation of SIV long terminal repeat activity and virus replication in macrophages

  2. Hepatitis A virus protein 2B suppresses beta interferon (show IFNA Proteins) (IFN) gene transcription by interfering with IFN regulatory factor 3 activation.

Cow (Bovine) Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. The data confirm the involvement of EHMT2 (show EHMT2 Proteins) in the epigenetic regulation of IFN-b and demonstrate the activation of a general antiviral state after EHMT2 (show EHMT2 Proteins) inhibition.

  2. The authors provide evidence that ICP27 protein encoded by bovine herpesvirus type 1, a viral early protein that shuttles between the nucleus and cytoplasm inhibits transcriptional activity of two bovine IFN-beta gene promoters (IFN-beta1 and IFN-beta3).

  3. The authors demonstrate that bovine herpesvirus 1 bICP0 effectively inhibits bovine IFN-beta promoter activity and induces IRF3 (show IRF3 Proteins) degradation.

  4. These studies provide evidence that virus infection differentially stimulates expression of the three bovine IFN-beta genes.

  5. recombinant bovine respiratory syncytial virus lacking the NS proteins, and those lacking NS2 in particular, are strong inducers of IFN-alpha (show IFNA Proteins)/beta in bovine nasal fibroblasts and bronchoalveolar macrophages.

Mouse (Murine) Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. The authors report that Raf kinase inhibitory protein (RKIP (show PEBP1 Proteins)) is essential for TBK1 (show TBK1 Proteins) activation and type I interferon (show IFNA Proteins) production triggered by viral infection.

  2. this study shows that paracrine type I IFN can profoundly enhance innate recognition and TLR2-dependent transcriptional responses to Francisella tularensis infection upstream of its role in inflammasome regulation in primary murine peritoneal macrophages but not murine bone marrow-derived macrophages

  3. STAT2 (show STAT2 Proteins) recruits USP18 (show USP18 Proteins) to the type I IFN receptor subunit IFNAR2 (show IFNAR2 Proteins) via its constitutive membrane-distal STAT2 (show STAT2 Proteins)-binding site.

  4. In the exorbital lachrymal gland, the mRNA expression of IFN beta and IFN alpha (type I IFNs) was weak- to strong-positive at 1 days post inoculation (DPI), and became negative at 2DPI.

  5. TBK1 (show TBK1 Proteins) complexes required for the phosphorylation of IRF3 (show IRF3 Proteins) and the production of interferon-beta have been identified.

  6. IRF-1 (show IRF1 Proteins) and interferon-alpha (show IFNA Proteins) with interferon-beta cooperate to control acute gammaherpesvirus infection.

  7. this study shows that endosomal signalling by Lactobacillus acidophilus that leads to IFN-beta production is inhibited by TLR stimulation from the plasma membrane

  8. Truncated rabies virus phosphoprotein isoforms promote viral replication in muscle cells through their IFN-beta antagonist activities and thereby support infection of peripheral nerves.

  9. identify iNOS (show NOS2 Proteins)/NO as an integral component of IFN-beta production in response to dsRNA in hepatocytes in a pathway that involves the coordinated activities of TLR3 (show TLR3 Proteins)/Trif (show RNF138 Proteins) and PKR (show EIF2AK2 Proteins)

  10. Data show that using adipose-derived mesenchymal stem cells (AD-MSCs) expressing interferon-beta (IFN-beta) as an anti-inflammatory agent, offer evidence supporting that the stem cell therapies in experimental autoimmune encephalomyelitis (EAE) may improve the valuable effects of IFN-beta in the autoimmune disease.

Human Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. Data suggest that EV71 infection in enterocytes does not inhibit phosphorylation of STAT1 (show STAT1 Proteins)/2 induced by IFN-beta, but p-STAT1 (show STAT1 Proteins)/2 transport into the nucleus is significantly blocked; EV71 infection in enterocytes down-regulates expression of KPNA1 (show KPNA1 Proteins) and induces degradation of cellular KPNA1 (show KPNA1 Proteins) via caspase-3 (show CASP3 Proteins). [EV17 = Enterovirus 71]

  2. This study reveals that decreased induction of both PKR (show PKLR Proteins) and p300 (show EP300 Proteins) proteins contribute to impaired induction of IFN-beta in Chronic obstructive pulmonary disease primary bronchial epithelial cells upon influenza infection.

  3. Together, these results suggest that RSV infection of MSCs alters their immune regulatory function by upregulating IFN-b and IDO (show IDO1 Proteins), affecting immune cell proliferation, which may account for the lack of protective RSV immunity and for chronicity of RSV-associated lung diseases such as asthma and COPD (show ARCN1 Proteins).

  4. ArfGAP domain-containing protein 2 (ADAP2 (show ADAP2 Proteins)) is identified as a key novel scaffolding protein that integrates different modules of the RIG-I (show DDX58 Proteins) pathway, located at distinct subcellular locations, and mediates cellular antiviral type I interferon (show IFNA Proteins) production.

  5. TBK1 (show TBK1 Proteins) complexes required for the phosphorylation of IRF3 (show IRF3 Proteins) and the production of interferon-beta have been identified.

  6. RNAs isolated from HCV-replicating cells triggered robust IFN-beta and IFN-lambda production through MDA5 (show IFIH1 Proteins).

  7. Plasmacytoid dendritic cells (pDCs) and type 1 interferon (show IFNA Proteins) (FNalpha/beta)frequently accompanied plasmablast/plasma cells (PB/PCs).

  8. These results suggest that inhibition of RIG-I (show DDX58 Proteins)-mediated type I interferon (show IFNA Proteins) responses by Enterovirus 71 may contribute to the pathogenesis of viral infection.

  9. the interactions of IRF1 (show IRF1 Proteins), IFN-beta and IRF5 (show IRF5 Proteins) are involved in the M1 polarization of macrophages and have antitumor functions.

  10. Data suggest that interferon beta (IFN-beta) might be involved in modulating the expressions of interferon regulatory factor 1 (IRF1 (show IRF1 Proteins)) and interferon regulatory factor-5 (show IRF5 Proteins) protein (IRF5 (show IRF5 Proteins)) as well as maintaining the M1 polarization status and its function.

Pig (Porcine) Interferon, beta 1, Fibroblast (IFNB1) interaction partners

  1. Nuclear export of NSP1alpha of porcine reproductive and respiratory syndrome virus was necessary for its ability for IFN beta inhibition.

  2. Porcine deltacoronavirus nsp5 (show SPECC1 Proteins), the 3C-like protease, inhibits interferon-beta production through the cleavage of NEMO (show IKBKG Proteins).

  3. Highly pathogenic Porcine reproductive and respiratory syndrome virus modulates Interferon-beta expression mainly through attenuating IRF-3 (show IRF3 Proteins) phosphorylation.

  4. Porcine epidemic diarrhea virus nsp1 inhibited the IFN-beta and IRF3 (show IRF3 Proteins) promoter activities.

  5. poIFIT3 plays a significant role in the clearance of swine influenza virus in pigs and potentiates IFN-beta production.

  6. DDX41 (show DDX41 Proteins) is involved in the dsDNA- and dsDNA-virus-mediated type IFN-beta signaling pathway in porcine kidney cells.

  7. VIral NS4 (show SOS1 Proteins) protein antagonizes beta interferon (show IFNA Proteins) expression by targeting the NF-kappaB (show NFKB1 Proteins) essential modulator.

  8. Swine IFN-beta promotes genetic mutation of porcine reproductive and respiratory syndrome virus.

  9. Expression of LSm14A (show LSM14A Proteins) in HEK293 or Marc (show CCL7 Proteins)-145 cells enhanced activities of IFN-beta and NF-kappaB (show NFKB1 Proteins) promoters, induced IFN-beta transcription, and potentiated IFN-beta promoter activation, indicating that LSm14A (show LSM14A Proteins) is a potential signal molecule (show WNT4 Proteins) in the IFN-beta pathway.

  10. Overall, data provide evidence for the possible role of PI3K in the activation of the transcription of IFN-alpha (show IFNA Proteins)/beta by PRRSV; study concludes that PRRSV inhibits the induction of IFN-alpha (show IFNA Proteins) in monocyte-derived dendritic cells by as yet undefined post-transcriptional mechanisms.

IFNB1 Protein Profile

Protein Summary

suppresses the growth of rat glioma cells

Alternative names and synonyms associated with IFNB1

  • interferon, beta 1, fibroblast (IFNB1)
  • interferon, beta 1, fibroblast (LOC100342931)
  • interferon (alpha, beta and omega) receptor 2 (IFNAR2)
  • interferon beta 1, fibroblast (Ifnb1)
  • interferon, beta 1, fibroblast (IFNB)
  • IFB protein
  • IFF protein
  • IFN-beta protein
  • IFN-R protein
  • IFN-R-2 protein
  • IFNb protein
  • IFNBR protein

Protein level used designations for IFNB1

interferon beta , interferon beta 1 , interferon, beta 1, fibroblast , IFN-alpha-REC , IFN-alpha/beta receptor 2 , interferon alpha/beta receptor 2 , interferon, beta; receptor , interferon-alpha/beta receptor 2 , interferon-alpha/beta receptor beta chain , type I interferon receptor 2 , IFN-beta , interferon, beta 1 , fibroblast interferon , interferon type B , interferon-beta , interferon beta-1

711414 Macaca mulatta
100342931 Oryctolagus cuniculus
282258 Bos taurus
15977 Mus musculus
24481 Rattus norvegicus
3456 Homo sapiens
554219 Gallus gallus
445459 Sus scrofa
493849 Felis catus
100052545 Equus caballus
481558 Canis lupus familiaris
281845 Bos taurus
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