Browse our anti-IL-4 (IL4) Antibodies

Full name:
anti-Interleukin 4 Antibodies (IL4)
On www.antibodies-online.com are 708 Interleukin 4 (IL4) Antibodies from 40 different suppliers available. Additionally we are shipping IL-4 Kits (278) and IL-4 Proteins (203) and many more products for this protein. A total of 1216 IL-4 products are currently listed.
Synonyms:
BCGF-1, BCGF1, BSF-1, BSF1, Il-4, IL2, IL4, Il4e12

All available anti-IL-4 Antibodies

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Top referenced anti-IL-4 Antibodies

  1. Human Monoclonal IL-4 Primary Antibody for FACS - ABIN1107850 : Moore, Zaki: Clinical cytokine network cytometry. in Clinics in laboratory medicine 2001 (PubMed)
    Show all 9 references for 1107850

  2. Human Monoclonal IL-4 Primary Antibody for EIA, FACS - ABIN119373 : Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. in Immunological reviews 1992 (PubMed)
    Show all 6 references for 119373

  3. Human Polyclonal IL-4 Primary Antibody for WB - ABIN3042695 : Presti, DOrazio, Labra, La Ferla, Mezzasalma, Bizzaro, Giardina, Michelotti, Tursi, Vassallo, Di Gennaro: Evaluation of the probiotic properties of new Lactobacillus and Bifidobacterium strains and their in vitro effect. in Applied microbiology and biotechnology 2015 (PubMed)
    Show all 5 references for 3042695

  4. Human Monoclonal IL-4 Primary Antibody for Inhibition, WB - ABIN967463 : Prussin, Metcalfe: Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. in Journal of immunological methods 1996 (PubMed)
    Show all 5 references for 967463

  5. Mouse (Murine) Monoclonal IL-4 Primary Antibody for ELISA - ABIN263080 : Xu, Liu, Fan, Yang, Korner, Fu, Uzonna: Lymphotoxin alpha beta 2 (membrane lymphotoxin) is critically important for resistance to Leishmania major infection in mice. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 4 references for 263080

  6. Human Monoclonal IL-4 Primary Antibody for FACS - ABIN4896835 : Eyerich, Pennino, Scarponi, Foerster, Nasorri, Behrendt, Ring, Traidl-Hoffmann, Albanesi, Cavani: IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. in The Journal of allergy and clinical immunology 2009 (PubMed)
    Show all 3 references for 4896835

  7. Mouse (Murine) Monoclonal IL-4 Primary Antibody for ELISA (Capture), EIA - ABIN118404 : Sander, Höidén, Andersson, Möller, Abrams: Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining. in Journal of immunological methods 1994 (PubMed)
    Show all 3 references for 118404

  8. Human Monoclonal IL-4 Primary Antibody for FACS - ABIN4896833 : Allard, Pletinckx, Breckpot, Heirman, Bonehill, Michiels, van Baalen, Gruters, Osterhaus, Lacor, Thielemans, Aerts: Functional T-cell responses generated by dendritic cells expressing the early HIV-1 proteins Tat, Rev and Nef. in Vaccine 2008 (PubMed)
    Show all 3 references for 4896833

  9. Human Polyclonal IL-4 Primary Antibody for WB - ABIN2785656 : Pachkoria, Lucena, Crespo, Ruiz-Cabello, Lopez-Ortega, Fernandez, Romero-Gomez, Madrazo, Durán, de Dios, Borraz, Navarro, Andrade: Analysis of IL-10, IL-4 and TNF-alpha polymorphisms in drug-induced liver injury (DILI) and its outcome. in Journal of hepatology 2008 (PubMed)

  10. Human Polyclonal IL-4 Primary Antibody for FACS, IHC (p) - ABIN651434 : Zhong, Zhou, Wu, Guo, Tan, Zhang, Zhang, Geng, Pan, Luo, Zhang, Xu, Liu, Liu, Gao, Liu, Ren, Li, Zhou, Zhang: A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomes. in Nucleic acids research 2015 (PubMed)

More Antibodies against IL-4 Interaction Partners

Human Interleukin 4 (IL4) interaction partners

  1. IL-4 signaling up-regulates the IL-25 (show IL25 Antibodies) axis in human monocytic cells, and IL-25 (show IL25 Antibodies) may provide autocrine signals in monocytes and macrophages to sustain IL-17Rb expression and predispose to alternative activation.

  2. IL4 VNTR B2 allele was only significantly associated with overall adiposity status before adjusting for ethnicity.

  3. Our results showed the role of IL4 in promoting breast cancer aggressiveness

  4. These data identified the IL-4/CXCL12 (show CXCL12 Antibodies) loop as a previously unrecognized pathway involved in lymphoid stroma polarization and as a potential therapeutic target in Follicular lymphoma patients.

  5. IL-4 genetic variations associated with susceptibility to or protection against chronic periodontitis are directly associated with influencing the response of immune cells to periodontopathogens

  6. in HIV/AIDS patients under antiretroviral therapy, IL-4 and IL-10 (show IL10 Antibodies) levels were significantly lower in lipodystrophy vs. non-lipodystrophy

  7. autologous CD4 (show CD4 Antibodies)(+) T cells that are exposed to EVs from CD40 (show CD40 Antibodies)/IL-4-stimulated CLL cells exhibit enhanced migration, immunological synapse signaling, and interactions with tumor cells.

  8. IL-4 substantially restores CD79b (show CD79B Antibodies) protein expression, sIgM expression, and BCR (show BCR Antibodies) signaling.

  9. Tandem repeat polymorphisms of IL4 is associated with the severity of chronic periodontitis.

  10. Keratinocyte gene expression is critically shaped by IL-4, altering cell fate decisions, which are likely important for the clinical manifestations and pathology of allergic skin disease

Mouse (Murine) Interleukin 4 (IL4) interaction partners

  1. IL-4 is required for the development of ex-Foxp3 (show FOXP3 Antibodies) T helper 2 cells.

  2. conclude that a state of haploinsufficiency for the Il4 gene locus is specifically relevant for IL-4-dependent IgE responses to allergens with the amount of IL-4 produced in the hemizygous condition falling close to the threshold required for switching to IgE production

  3. priming of T helper cells by IL-6 (show IL6 Antibodies)-deficient antigen-presenting dendritic cells preferentially leads to accumulation of a subset of Follicular helper T cells characterized by high expression of GATA3 (show GATA3 Antibodies) and IL-4.

  4. eosinophils drive progression of myocarditis to Inflammatory dilated cardiomyopathy (DCMi), cause severe DCMi when present in large numbers, and mediate this process through IL-4.

  5. These data suggest that although IL-4-stimulated alternatively activated macrophages upregulate fatty acid oxidation, fatty acid oxidation is dispensable for macrophage polarization and high-fat diet-induced metabolic dysfunction. Macrophage fatty acid oxidation likely plays a correlative, rather than causative, role in systemic metabolic dysfunction.

  6. Excessive IL-4 levels in the mesenteric lymph nodes (MLNs) directly inhibited the induction of aiTregs and caused enteropathy. The aiTregs generated in the attenuation of T cell-dependent food allergic enteropathy may function differently than aiTregs induced in a tolerance model.

  7. this study shows that IL-4 and IL-10 (show IL10 Antibodies) are important for the altered peptide ligand-induced attenuation of experimental arthritis

  8. this study shows that wild-type mice develop an eosinophilic Th2 airway disease in response to Alternaria alternata exposure, whereas IL-4-deficient mice exhibit a primarily neutrophilic response

  9. Study showed that the intraperitoneal administration of the exogenous cytokines IFN-gamma (show IFNG Antibodies) (to promote M1 microglia ) and IL-4 (to promote M2 microglia) can correctly modulate the timing of the M1 to M2 ratio to affect epileptogenesis and to improve cognitive function in pilocarpine-induced status epilepticus.

  10. These findings indicate that IL-4, a canonical Th2 cell cytokine, can sometimes promote rather than impair Th1 (show HAND1 Antibodies) cell-type immune responses

Cow (Bovine) Interleukin 4 (IL4) interaction partners

  1. These results support pregnancy as type 2 immune response biased, with increases of IFN-gamma (show IFNG Antibodies) occurring after parturition and an increase in IL-4 production before calving.

  2. IL-4 may play a role in coordinating the adrenal response to inflammatory stress.

  3. T helper (Th) type 2 cell cytokine IL-4 modulates airway contraction by secreting matrix metalloproteinase-1 (show MMP1 Antibodies) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.

Pig (Porcine) Interleukin 4 (IL4) interaction partners

  1. IL-4- and IL-10 (show IL10 Antibodies)-producing invariant NKT (show SLC22A6 Antibodies) cells inhibit the Th1 (show TH1L Antibodies) cell response, but not the Th17 cell response

  2. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  3. There was no significant difference of IL-4 production between fresh and frozen peripheral blood mononuclear cells.

  4. The endothelium and subendothelium of porcine iliac arteries that are transduced with recombinant pig IL-4 are effectively protected from complement-dependent immediate injury after perfusion with human blood.

  5. unlike in humans and mice, porcine IL-4 blocks antibody and IL-6 (show IL6 Antibodies) secretion and suppresses antigen-stimulated proliferation of B cells

Guinea Pig Interleukin 4 (IL4) interaction partners

  1. Data indicate that animals exposed to high lead concentration, the levels of IFNgamma and IFNgamma/IL-4 ratio were significantly lower than those exposed to its low concentration.

  2. IL-4 and STAT6 (show STAT6 Antibodies) are related to the pathogenesis of allergic rhinitis and may be the main factors for eosinophil infiltration in allergic rhinitis.

Horse (Equine) Interleukin 4 (IL4) interaction partners

  1. The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Antibodies) biased, interferon-gamma (show IFNG Antibodies) production is qualitatively similar to adult horses, and regulatory IL-10 (show IL10 Antibodies) production by T cells is mature.

  2. This study showed that pronounced lung eosinophilia in horses can be transient, abate without specific treatment, and in this instance, lack correlation to upregulation of expression of either IL-4 or IL-5 (show IL5 Antibodies).

Rhesus Monkey Interleukin 4 (IL4) interaction partners

  1. Low Sociable animals showed alterations in lymph node expression of the immunoregulatory cytokine genes IL4.

  2. Mycobacterial infections of macaques induce mRNA encoding a variant IL-4 that functions as a growth factor to promote expansion of 4-hydroxy-3-methyl-but-2-enyl pyrophosphate-specific Vgamma2Vdelta2 T effector cells.

IL-4 (IL4) Antigen Profile

Antigen Summary

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alternative names and synonyms associated with IL-4 (IL4)

  • interleukin 4 (IL4) antibody
  • interleukin 4 (Il4) antibody
  • interleukin 4 (Il-4) antibody
  • BCGF-1 antibody
  • BCGF1 antibody
  • BSF-1 antibody
  • BSF1 antibody
  • Il-4 antibody
  • IL2 antibody
  • IL4 antibody
  • Il4e12 antibody

Protein level used designations for anti-Interleukin 4 (IL4) Antibodies

interleukin 4 , B cell growth factor 1 , B_cell stimulatory factor 1 , binetrakin , interleukin-4 , lymphocyte stimulatory factor 1 , pitrakinra , B-cell IgG differentiation factor , B-cell growth factor 1 , B-cell stimulatory factor 1 , IGG1 induction factor , B-cell IGG differentiation factor , BSF-1 , IL-4 , Lymphocyte stimulatory factor 1

GENE ID SPECIES
100126747 Papio anubis
3565 Homo sapiens
16189 Mus musculus
287287 Rattus norvegicus
280824 Bos taurus
397225 Sus scrofa
403785 Canis lupus familiaris
100860814 Capra hircus
443327 Ovis aries
416330 Gallus gallus
101801081 Anas platyrhynchos
100720403 Cavia porcellus
100302454 Oryctolagus cuniculus
100034225 Equus caballus
751514 Felis catus
574281 Macaca mulatta
100482473 Ailuropoda melanoleuca
101843742 Mesocricetus auratus
449565 Pan troglodytes
101338293 Tursiops truncatus
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