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Human IL7 ELISA Kit for Sandwich ELISA - ABIN625028
Meltzer, Standley: Modeled repetitive motion strain and indirect osteopathic manipulative techniques in regulation of human fibroblast proliferation and interleukin secretion. in The Journal of the American Osteopathic Association 2008
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Mouse (Murine) IL7 ELISA Kit for Sandwich ELISA - ABIN625152
Jung, Han, Kim, Kim, Lee, Seo, Youn, Lee: Stimulatory effect of HGF-overexpressing adipose tissue-derived mesenchymal stem cells on thymus regeneration in a rat thymus involution model. in Cell biology international 2014
Rat (Rattus) IL7 ELISA Kit for Sandwich ELISA - ABIN1115680
Dai, Wu, Li, Chen, Chen, Hu, Shen: Effects and mechanisms of Geniposide on rats with adjuvant arthritis. in International immunopharmacology 2014
increased IL-7 protein production in situ (lung tissue) from non-human primates who received rBCG vaccination, which was associated with increased survival.
this study shows that IL-7 restores T Lymphocyte immunometabolic failure in septic shock patients through mTOR (show FRAP1 ELISA Kits) activation
In CRC (show CALR ELISA Kits), IL-7 was higher in patients with lymph node and distant metastases and with tumors located in right colon. In adenomas, IL-7 elevation was associated exclusively with villous growth pattern, while in IBD, circulating IL-7 reflected clinical activity of Crohn's disease and ulcerative colitis.
Tuberculosis patients had lower soluble IL-7R and higher IL-7 plasma concentrations as compared to healthy contacts.
CD56 (show NCAM1 ELISA Kits)(bright) NK IL-7Ralpha (show IL7R ELISA Kits) expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections
IL-7 has a role inducing epitope masking of gammac protein in IL-7 receptor signaling complex
Therefore, generalized CD8 (show CD8A ELISA Kits)+ T-cell impairment in HCV infection is characterized, in part, by impaired IL-7-mediated signalling and survival, independent of CD127 (show IL7R ELISA Kits) expression. This impairment is more pronounced in the liver and may be associated with an increased potential for apoptosis. This generalized CD8 (show CD8A ELISA Kits)+ T-cell impairment represents an important immune dysfunction in chronic HCV infection that may alter patient health.
These results reveal a novel role of IL-7 and IL-15 (show IL15 ELISA Kits) in maintaining human T cell function, provide an explanation for T cell dysfunction in humanized mice, and have significant implications for in vitro studies with human T cells.
The results show that SNPs in IL7 caused a significant association in this OA Chinese Han population.
IL-7 is capable of enhancing functional T cell activity without causing significant functional inbalance between various T cell subsets.
A compensatory mechanism of IL-7-mediated homeostatic proliferation can restore the inhibitory network of CD24 (show CD24 ELISA Kits)+Foxp3 (show FOXP3 ELISA Kits)+Treg cell after anti-CD25 (show IL2RA ELISA Kits) induction therapy in islet allotransplantation.
this study shows that IL-7 homeostasis is achieved through consumption by multiple subsets of innate and adaptive immune cells
lymphatic vessel expansion occurs in two distinct phases; the first wave of expansion is dependent on IL-7; the second phase, responsible for leukocyte exit from the glands, is regulated by lymphotoxin (show LTB ELISA Kits) (LT)betaR signaling
DNM2 (show DNM2 ELISA Kits) mutations cooperate with Lmo2 (show LMO2 ELISA Kits) T-cell oncogenes by enhancing IL-7 signalling.
IL-7 responsiveness in RTE is designed to maximize survival at the expense of reduced proliferation, consistent with RTE serving as a subpopulation of T cells rich in diversity but not in frequency.
Expression of IL-7 is beneficial for induction of potent and long-lasting humoral immune responses.
findings support a redundant role for adaptive Th17 cell- and innate gammadeltaT17 cell-derived IL17 (show IL17A ELISA Kits) in bacteria-induced colon carcinogenesis, stressing the importance of therapeutically targeting the cytokine itself rather than its cellular sources
functional Gimap5 is required for optimal signaling through TCR and IL-7R in T cells.
continuous IL7 signaling was not required for tumor regression, although LIP of naive CD8 (show CD8A ELISA Kits)+ T cells is usually regulated by IL7
IL7 represses the follicular helper T cell gene program.
This study uncovers the metabolic mechanisms by which IL-7 tailors the metabolism of memory T cells to promote their longevity and fast response to rechallenge.
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.