Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Mouse (Murine) Leptin Receptor ELISA Kit for Sandwich ELISA - ABIN1672740
Park, Shin, Park, Cheong, Cho, Lee, Lee, Lee, Oh, Kimm: Polymorphisms in the leptin receptor (LEPR)--putative association with obesity and T2DM. in Journal of human genetics 2006
Show all 4 references for ABIN1672740
Rat (Rattus) Leptin Receptor ELISA Kit for Sandwich ELISA - ABIN416360
Feng, Shao, Weijdegård, Wang, Johansson, Sun, Wang, Egecioglu, Billig, Stener-Victorin: Effects of androgen and leptin on behavioral and cellular responses in female rats. in Hormones and behavior 2011
Human Leptin Receptor ELISA Kit for Sandwich ELISA - ABIN365403
Catli, Anik, Tuhan, Kume, Bober, Abaci: The relation of leptin and soluble leptin receptor levels with metabolic and clinical parameters in obese and healthy children. in Peptides 2014
The LEPR rs1805134 polymorphism could be involved in the development of morbid obesity in a Mexican population
maternal and neonatal LEP (show LEP ELISA Kits) and LEPR polymorphisms are significantly associated with increased risk for preterm birth.
Studies reported different mutations in the LEPR have been reported as c.2396-1 G>T, c.1675 G>A, p.P316T related to obesity. [review]
Our meta-analysis suggested a significant association between the LEPR Pro1019Pro polymorphism and T2DM risk
Results suggest that leptin/leptin (show LEP ELISA Kits) receptor signaling may represent a potential therapeutic target that can block the stromal-tumor interactions driving breast cancer stem cells (BCSCs)-mediated disease progression.
Polymorphism of rs2767485 in leptin receptor(LEPR) gene is associated with the occurrence of adolescent idiopathic scoliosis in the Chinese Han population, suggesting LEPR is a predisposition gene.
Gene polymorphism of leptin (loci rs7799039) and leptin receptor (loci rs1137101) are correlated with Growth hormone deficiency susceptibility.
Despite the lack of association observed for LEPR Q223R and TNF-alpha (show TNF ELISA Kits) G-308A, Indian and Chinese subjects with AA risk genotype for LEPR Q223R/LEP (show LEP ELISA Kits) G-2548A and TNF-alpha (show TNF ELISA Kits) G-308A/LEP (show LEP ELISA Kits) G-2548A, respectively, had increased mean BMI
Here we propose that assessing sOb-R levels in addition to leptin (show LEP ELISA Kits) concentrations in breast milk could serve as a valuable tool to investigate effects of the leptin (show LEP ELISA Kits) axis in breast milk.
Lys656Asn Polymorphism of Leptin Receptor Gene is associated with Cardiovascular disease.
Leptin receptor expressing neurons express phosphodiesterase-3B (PDE3B) and leptin induces STAT3 activation in PDE3B neurons in the mouse hypothalamus.
JAK (show JAK3 ELISA Kits)-STAT (show STAT1 ELISA Kits) and hormone biosynthesis pathways were involved in the follicular development and ovulation disorders caused by LepR deficiency in ovaries
Global loss of the leptin receptor results in reduced viral clearance and worse outcomes following influenza A infection.
Human and murine pancreatic cancer cell lines were found to express the short as well as the long form of the leptin receptor and functionally responded to leptin (show LEP ELISA Kits) induced activation through an increased phosphorylation of AKT473.
leptin (show LEP ELISA Kits) of dermal white adipose tissue might regulate hair growth and, therefore, hair cycle progression via leptin receptor on the hair follicle epithelium
absence of leptin receptor on thymic epithelial cells or T cells does not lead to the loss of thymic function, demonstrating the thymoprotective effect of leptin (show LEP ELISA Kits) is mediated by obesity suppression rather than signalling to the thymus.
High LEPR expression is associated with onset of obesity.
The newly recognized effect of the leptin receptor Q223R mutation on diminished neutrophil chemotaxis and the impact of this mutation on multiple infectious diseases suggest a broader impact of this mutation on susceptibility to disease.
data suggest that both adipose and placenta-derived leptin (show LEP ELISA Kits) system are involved in the regulation of energy metabolism during fetal growth.
LepR(+) cells are the major source of bone and adipocytes in adult bone marrow
LEPR showed a lower variability than LEP (show LEP ELISA Kits) in the different analysed populations, especially in the Iberian breed that showed no variability
Superactive human leptin (show LEP ELISA Kits) antagonist reverses leptin (show LEP ELISA Kits)-induced excessive progesterone and testosterone secretion in porcine ovarian follicles by blocking leptin (show LEP ELISA Kits) receptors.
The presence of leptin (show LEP ELISA Kits) and ObR-b varies across parities and is more intense in the uterus, ovaries and hypothalamus of females that were cycling before culling than in those having cystic ovaries.
These results suggest that LEPR, MC4R, PIK3C3 and VRTN are useful markers for accurately predicting breeding values in Duroc pigs.
Data showing changes in expression patterns of LEP (show LEP ELISA Kits)/LEPR in endometrium/chorioallantoic membrane during placentation/fetal development suggest role for LEP (show LEP ELISA Kits)/LEPR complex at early stages of pregnancy, possibly affecting the attachment process.
Another funning discovery is ob-Rb mRNA in porcine endometrium was mainly negative-regulated by leptin (show LEP ELISA Kits)
Leptin (show LEP ELISA Kits) and leptin receptor are expressed in porcine luteal cells, and there is a modulatory effect of LH, estradiol (E) and progesterone (P) on leptin (show LEP ELISA Kits) mRNA expression as well as E and P on leptin (show LEP ELISA Kits) secretion by those cells obtained in early pregnancy.
These data suggest that leptin (show LEP ELISA Kits) might have a direct effect on porcine follicles and plays an important role in the follicular development.
Locally produced leptin (show LEP ELISA Kits) plays a role in the regulation of porcine reproduction at the ovarian level and exerts a direct effect on follicles. Differences in long isoform of leptin receptor gene expression varies in the ovaries of pregnant and cyclic pigs.
results suggest the T alleles of both LEP (show LEP ELISA Kits) g.1387C>T and LEPR c.1987C>T, which are fixed in the Iberian pigs, would lead to an increase in growth, fatness and saturated fatty acid content in fat, which could be explained by an increased feed intake
I3 DNA copy number variations exhibited a significant negative correlation with LEPR gene expression
The results suggest that a mutation of SCD1 (show SCD ELISA Kits), but not LEPR or ABCG2 (show ABCG2 ELISA Kits), might be useful as a DNA marker to decrease reproductive problems and improve production traits in Iranian Holstein dairy cows.
SNP LEP (show LEP ELISA Kits) significantly affected milk, protein and fat yield (P<0.05), and age at first calving (P<0.01) in analyzed population of cows. SNP LEPR/T945M affected significantly calving interval (P<0.01) only
The use of leptin (show LEP ELISA Kits), leptin receptor, and DGAT1 (show DGAT1 ELISA Kits) polymorphisms as markers within genetic selection programs to improve and adjust several compositional parameters.
The leptin (show LEP ELISA Kits) and receptor gene markers would be useful for marker-assisted selection.
The leptin receptor SNP (T945M) was only weakly associated with milk per day and days to first service.
The presence of the leptin receptor in bull spermatozoa was analyzed by RT-PCR and Southern hybridization and perhaps exerts physiologic effects.
the possible involvement of locally produced leptin (show LEP ELISA Kits)/Ob-R system in the bovine ovary, suggesting roles in the function and/or development of the CL and growth of small follicles in an autocrine/paracrine fashion.
findings indicate that acetate and butyrate enhance leptin (show LEP ELISA Kits) expression in bovine, but not in rat anterior pituitary cells while butyrate suppresses leptin receptor expression in both rat and bovine pituitaries
leptin receptor is expressed in the bovine corpus luteum and is modulated by leptin (show LEP ELISA Kits).
A 2-day fast increased leptin receptor (Ob-R) expression in the ventromedial nucleus (VMN).
These results indicate that horse major salivary glands, like those of humans, are likely targets of leptin (show LEP ELISA Kits) actions, suggesting a functional role of leptin (show LEP ELISA Kits) on these glands.
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).
, leptin receptor gene-related protein
, Leptin receptor (fatty)
, cytokine receptor
, leptin receptor long insert isoform
, OB-R gene-related protein