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Browse our Leptin Receptor (LEPR) ELISA Kits

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Leptin Receptor ELISA Kits (LEPR)
On are 66 Leptin Receptor (LEPR) ELISA Kits from 16 different suppliers available. Additionally we are shipping Leptin Receptor Antibodies (229) and Leptin Receptor Proteins (25) and many more products for this protein. A total of 329 Leptin Receptor products are currently listed.
CD295, db, diabetes, Fa, LEP-R, LEPR, Leprb, LEPRD, LEPROT, Modb1, Ob-R, ob-rb, OB-RGRP, Ob-RM, obese-like, obl, Obr, ObRb, Obrgrp, VPS55

Top referenced Leptin Receptor ELISA Kits

  1. Mouse (Murine) Leptin Receptor ELISA Kit for Sandwich ELISA - ABIN1672740 : Park, Shin, Park, Cheong, Cho, Lee, Lee, Lee, Oh, Kimm: Polymorphisms in the leptin receptor (LEPR)--putative association with obesity and T2DM. in Journal of human genetics 2006 (PubMed)
    Show all 4 references for ABIN1672740

  2. Human Leptin Receptor ELISA Kit for Sandwich ELISA - ABIN365403 : Catli, Anik, Tuhan, Kume, Bober, Abaci: The relation of leptin and soluble leptin receptor levels with metabolic and clinical parameters in obese and healthy children. in Peptides 2014 (PubMed)

  3. Rat (Rattus) Leptin Receptor ELISA Kit for Sandwich ELISA - ABIN416360 : Feng, Shao, Weijdegård, Wang, Johansson, Sun, Wang, Egecioglu, Billig, Stener-Victorin: Effects of androgen and leptin on behavioral and cellular responses in female rats. in Hormones and behavior 2011 (PubMed)

More ELISA Kits for Leptin Receptor Interaction Partners

Human Leptin Receptor (LEPR) interaction partners

  1. leptin (show LEP ELISA Kits)-LepRb plays an important role in the pathogenesis and depression in gastric cancer

  2. In 2 unrelated girls with severe obesity, three novel LEPR mutations were detected. Longitudinal growth data show normal childhood growth, and in the older girl, a normal adult height despite hypogonadotropic hypogonadism and the lack of an obvious pubertal growth spurt (show BPIFA1 ELISA Kits).

  3. genetic variability in the LEPR gene is associated with idiopathic recurrent spontaneous abortion; more frequent LEPR genotype in patients - rs7516341 (nominal P=0.034, odds ratio [OR] 0.61, 95% confidence interval [CI] 0.38-0.97) and rs1137101 (nominal P=0.048, OR 1.66, 95% CI 1.00-2.80)

  4. our findings suggest that leptin (show LEP ELISA Kits) promoted the proliferation, migration and invasion of gallbladder cancer (GBC) cells by increasing OB-Rb expression through the SOCS3 (show SOCS3 ELISA Kits)/JAK2 (show JAK2 ELISA Kits)/p-STAT3 (show STAT3 ELISA Kits) signal pathway. Targeting the leptin (show LEP ELISA Kits)/OB-Rb axis could be an attractive therapeutic strategy for treatment of GBC.

  5. genetic association studies in population of children (ages 5-10 years) in Poland: Data suggest that SNPs in LEPR are associated with predisposition to weight loss while engaging in lifestyle modifications for treatment of pediatric obesity in the population studied; carriers of wild-type K665N and at least one minor Q223R allele indicate greatest likelihood of losing weight.

  6. The placental weight ratio exerted a positive effect on the placental mRNA expression of insulin- like growth factor-I (show IGF1 ELISA Kits) and the long isoform of the leptin receptor in malaria-infected pregnant women without fever or chill symptoms.

  7. Data showed that TNF-a (show TNF ELISA Kits) and IL-6 (show IL6 ELISA Kits) polymorphisms were associated with overall and site-specific osteoporosis in both sexes, and that these associations were dependent on rs1805096 and rs1892534 genotypes of LEPR.

  8. Genetic alterations in the leptin (show LEP ELISA Kits), LEPR and MC$R genes are associated with severe obesity.

  9. Effects of leptin (show LEP ELISA Kits) and leptin receptor SNPs on clinical- and metabolic-related traits in apparent treatment-resistant hypertension.

  10. this study shows the role of LEPR polymorphisms in the risk of multiple sclerosis and its severity in Iran

Mouse (Murine) Leptin Receptor (LEPR) interaction partners

  1. Leptin receptor expressing neurons express phosphodiesterase-3B (PDE3B) and leptin induces STAT3 activation in PDE3B neurons in the mouse hypothalamus.

  2. JAK (show JAK3 ELISA Kits)-STAT (show STAT1 ELISA Kits) and hormone biosynthesis pathways were involved in the follicular development and ovulation disorders caused by LepR deficiency in ovaries

  3. Global loss of the leptin receptor results in reduced viral clearance and worse outcomes following influenza A infection.

  4. Human and murine pancreatic cancer cell lines were found to express the short as well as the long form of the leptin receptor and functionally responded to leptin (show LEP ELISA Kits) induced activation through an increased phosphorylation of AKT473.

  5. leptin (show LEP ELISA Kits) of dermal white adipose tissue might regulate hair growth and, therefore, hair cycle progression via leptin receptor on the hair follicle epithelium

  6. absence of leptin receptor on thymic epithelial cells or T cells does not lead to the loss of thymic function, demonstrating the thymoprotective effect of leptin (show LEP ELISA Kits) is mediated by obesity suppression rather than signalling to the thymus.

  7. High LEPR expression is associated with onset of obesity.

  8. The newly recognized effect of the leptin receptor Q223R mutation on diminished neutrophil chemotaxis and the impact of this mutation on multiple infectious diseases suggest a broader impact of this mutation on susceptibility to disease.

  9. data suggest that both adipose and placenta-derived leptin (show LEP ELISA Kits) system are involved in the regulation of energy metabolism during fetal growth.

  10. LepR(+) cells are the major source of bone and adipocytes in adult bone marrow

Pig (Porcine) Leptin Receptor (LEPR) interaction partners

  1. LEPR showed a lower variability than LEP (show LEP ELISA Kits) in the different analysed populations, especially in the Iberian breed that showed no variability

  2. Superactive human leptin (show LEP ELISA Kits) antagonist reverses leptin (show LEP ELISA Kits)-induced excessive progesterone and testosterone secretion in porcine ovarian follicles by blocking leptin (show LEP ELISA Kits) receptors.

  3. The presence of leptin (show LEP ELISA Kits) and ObR-b varies across parities and is more intense in the uterus, ovaries and hypothalamus of females that were cycling before culling than in those having cystic ovaries.

  4. These results suggest that LEPR, MC4R, PIK3C3 and VRTN are useful markers for accurately predicting breeding values in Duroc pigs.

  5. Data showing changes in expression patterns of LEP (show LEP ELISA Kits)/LEPR in endometrium/chorioallantoic membrane during placentation/fetal development suggest role for LEP (show LEP ELISA Kits)/LEPR complex at early stages of pregnancy, possibly affecting the attachment process.

  6. Another funning discovery is ob-Rb mRNA in porcine endometrium was mainly negative-regulated by leptin (show LEP ELISA Kits)

  7. Leptin (show LEP ELISA Kits) and leptin receptor are expressed in porcine luteal cells, and there is a modulatory effect of LH, estradiol (E) and progesterone (P) on leptin (show LEP ELISA Kits) mRNA expression as well as E and P on leptin (show LEP ELISA Kits) secretion by those cells obtained in early pregnancy.

  8. These data suggest that leptin (show LEP ELISA Kits) might have a direct effect on porcine follicles and plays an important role in the follicular development.

  9. Locally produced leptin (show LEP ELISA Kits) plays a role in the regulation of porcine reproduction at the ovarian level and exerts a direct effect on follicles. Differences in long isoform of leptin receptor gene expression varies in the ovaries of pregnant and cyclic pigs.

  10. results suggest the T alleles of both LEP (show LEP ELISA Kits) g.1387C>T and LEPR c.1987C>T, which are fixed in the Iberian pigs, would lead to an increase in growth, fatness and saturated fatty acid content in fat, which could be explained by an increased feed intake

Cow (Bovine) Leptin Receptor (LEPR) interaction partners

  1. Here, the association between DGAT1 (show DGAT1 ELISA Kits) K232A, SCD1 (show SCD ELISA Kits) A293V, and LEPR T945M markers with milk fat composition in southern Chile was evaluated. We genotyped the SNPs and calculated allele frequencies and Hardy-Weinberg equilibrium. The most frequent variants for DGAT1 (show DGAT1 ELISA Kits), SCD1 (show SCD ELISA Kits), and LEPR polymorphisms were GC/GC (show GC ELISA Kits), C, and C, respectively.

  2. I3 DNA copy number variations exhibited a significant negative correlation with LEPR gene expression

  3. The results suggest that a mutation of SCD1 (show SCD ELISA Kits), but not LEPR or ABCG2 (show ABCG2 ELISA Kits), might be useful as a DNA marker to decrease reproductive problems and improve production traits in Iranian Holstein dairy cows.

  4. SNP LEP (show LEP ELISA Kits) significantly affected milk, protein and fat yield (P<0.05), and age at first calving (P<0.01) in analyzed population of cows. SNP LEPR/T945M affected significantly calving interval (P<0.01) only

  5. The use of leptin (show LEP ELISA Kits), leptin receptor, and DGAT1 (show DGAT1 ELISA Kits) polymorphisms as markers within genetic selection programs to improve and adjust several compositional parameters.

  6. The leptin (show LEP ELISA Kits) and receptor gene markers would be useful for marker-assisted selection.

  7. The leptin receptor SNP (T945M) was only weakly associated with milk per day and days to first service.

  8. The presence of the leptin receptor in bull spermatozoa was analyzed by RT-PCR and Southern hybridization and perhaps exerts physiologic effects.

  9. the possible involvement of locally produced leptin (show LEP ELISA Kits)/Ob-R system in the bovine ovary, suggesting roles in the function and/or development of the CL and growth of small follicles in an autocrine/paracrine fashion.

  10. findings indicate that acetate and butyrate enhance leptin (show LEP ELISA Kits) expression in bovine, but not in rat anterior pituitary cells while butyrate suppresses leptin receptor expression in both rat and bovine pituitaries

Rhesus Monkey Leptin Receptor (LEPR) interaction partners

  1. A 2-day fast increased leptin receptor (Ob-R) expression in the ventromedial nucleus (VMN).

Horse (Equine) Leptin Receptor (LEPR) interaction partners

  1. These results indicate that horse major salivary glands, like those of humans, are likely targets of leptin (show LEP ELISA Kits) actions, suggesting a functional role of leptin (show LEP ELISA Kits) on these glands.

Leptin Receptor (LEPR) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).

Alternative names and synonyms associated with Leptin Receptor (LEPR)

  • leptin receptor (lepr) Elisa Kit
  • leptin receptor (LEPR) Elisa Kit
  • leptin receptor (Lepr) Elisa Kit
  • leptin receptor overlapping transcript (Leprot) Elisa Kit
  • Leptin receptor-like (LOC100351924) Elisa Kit
  • leptin receptor-like (LOC100069504) Elisa Kit
  • CD295 Elisa Kit
  • db Elisa Kit
  • diabetes Elisa Kit
  • Fa Elisa Kit
  • LEP-R Elisa Kit
  • LEPR Elisa Kit
  • Leprb Elisa Kit
  • LEPRD Elisa Kit
  • LEPROT Elisa Kit
  • Modb1 Elisa Kit
  • Ob-R Elisa Kit
  • ob-rb Elisa Kit
  • OB-RGRP Elisa Kit
  • Ob-RM Elisa Kit
  • obese-like Elisa Kit
  • obl Elisa Kit
  • Obr Elisa Kit
  • ObRb Elisa Kit
  • Obrgrp Elisa Kit
  • VPS55 Elisa Kit

Protein level used designations for Leptin Receptor (LEPR) ELISA Kits

OB receptor , huB219 , B219 , LEP-R , leptin receptor gene-related protein , OB-R , Leptin receptor (fatty) , cytokine receptor , leptin receptor long insert isoform , OB-R gene-related protein

724071 Xenopus (Silurana) tropicalis
3953 Homo sapiens
450207 Canis lupus familiaris
16847 Mus musculus
396836 Sus scrofa
497205 Bos taurus
24536 Rattus norvegicus
100725434 Cavia porcellus
374223 Gallus gallus
443264 Ovis aries
574126 Macaca mulatta
230514 Mus musculus
100351924 Oryctolagus cuniculus
100069504 Equus caballus
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