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Human LIF ELISA Kit for Sandwich ELISA - ABIN625036
Krishnan, Winship, Sonderegger, Menkhorst, Horne, Brown, Zhang, Nicola, Tong, Dimitriadis: The role of leukemia inhibitory factor in tubal ectopic pregnancy. in Placenta 2013
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Rat (Rattus) LIF ELISA Kit for Sandwich ELISA - ABIN416358
Tu, Kang, Ho, Liou, Liou, Lin, Fu: Leukemia inhibitory factor (LIF) potentiates antinociception activity and inhibits tolerance induction of opioids. in British journal of anaesthesia 2017
Authors demonstrate heterozygous novel or rare LIFR (show LIFR ELISA Kits) mutations in 3.3% of CAKUT patients, and provide evidence that Lifr (show LIFR ELISA Kits) deficiency and deactivating LIFR (show LIFR ELISA Kits) mutations cause highly similar anomalies of the urogenital tract in mice and humans.
lung epithelium, specifically alveolar type II cells, is the predominant site of LIF transcript induction in pneumonic mouse lungs.
LIF/STAT3 (show STAT3 ELISA Kits) and MEK (show MDK ELISA Kits)/ERK (show EPHB2 ELISA Kits) signaling in naive embryonic stem cell pluripotency, is reported.
uterine expression of the LIFR (show LIFR ELISA Kits) is essential for embryo implantation; this further define the components of the LIF signaling pathway necessary for effective implantation.
LIF stimulates, in part, stem cell-derived cardiomyocyte regeneration by activating cardiac stem or precursor cells.
Our data show that absence of SOCS2 (show SOCS2 ELISA Kits) turns cardiomyocytes unresponsive to LIF-induced [Ca(2 (show CA2 ELISA Kits)+)] raise, indicating that endogenous levels of SOCS2 (show SOCS2 ELISA Kits) are crucial for full activation of LIF signaling in the heart.
OSM (mOSM) signals mainly via an OSM receptor (OSMR)-gp130 heterodimer and binds with only very low affinity to mLIFR.
These results establish that Bcl3 (show BCL3 ELISA Kits) positively regulates pluripotency genes and thus shed light on the mechanism of Bcl3 (show BCL3 ELISA Kits) as a downstream molecule of LIF/STAT3 (show STAT3 ELISA Kits) signaling in pluripotency maintenance.
The role of LIF in acetylcholine synthesis via the STAT3 (show STAT3 ELISA Kits), PI3 (show PI3 ELISA Kits) kinases, or cAMP-protein kinase A pathways, are reported.
Either LIF or EGF (show EGF ELISA Kits) is needed during development of pre-implantation embryo.
These results demonstrate the involvement of PIM (show PIM1 ELISA Kits) kinases in LIF-induced regulation in different trophoblastic cell lines which may indicate similar functions in primary cells.
Data suggest a 216-nucleotide proximal cis (show CISH ELISA Kits)-element in LIF mRNA exhibits mRNA destabilizing potential; on exposure to carcinogen PMA (phorbol-12-myristate-13-acetate), this cis (show CISH ELISA Kits)-element exhibits mRNA stabilizing activity. PMA induces nucleo-cytoplasmic translocation of both nucleolin (show NCL ELISA Kits) and PCBP1 (show PCBP1 ELISA Kits), 2 trans-acting factors that bind to and stabilize LIF mRNA. [LIF = leukemia inhibitory factor; PCBP1 (show PCBP1 ELISA Kits) = poly(rC) binding protein 1 (show PCBP1 ELISA Kits)]
Leukemia inhibitory factor (LIF) - STAT3 (show STAT3 ELISA Kits) transcription factor (STAT3 (show STAT3 ELISA Kits)) signaling pathway is systemically dysregulated in in the endometrium of patients with recurrent/repeated implantation failure (RIFE).
Endometrial expression of LIF and LIFR (show LIFR ELISA Kits) is significantly reduced in the epithelial cells of infertile women.
LIF SNP T/G (rs929271) seems to be a susceptibility biomarker capable of predicting implantation efficiency and pregnancy outcomes.
Overexpression of LIF promotes Epithelial-mesenchymal transition and results in cancer.
This review discusses the role of LIF and the recent analysis of its action on the uterine LE in regulating endometrial receptivity and implantation.
Women with dormant genital tuberculosis were found to have decreased endometrial LIF-STAT3 (show STAT3 ELISA Kits) signaling.
Data show that leukemia inhibitory factor (LIF) signaling promote chemoresistance in cholangiocarcinoma by up-regulating myeloid cell factor-1 (Mcl-1 (show MCL1 ELISA Kits)) via phosphatidylinositol 3-kinase (PI3K (show PIK3CA ELISA Kits))/c-akt (show AKT1 ELISA Kits) protein (AKT (show AKT1 ELISA Kits))-dependent pathway.
Despite common signal transduction mechanisms (JAK (show JAK3 ELISA Kits)/STAT (show STAT1 ELISA Kits), MAPK (show MAPK1 ELISA Kits) and PI3K (show PIK3CA ELISA Kits)) LIF can have paradoxically opposite effects in different cell types including stimulating or inhibiting each of cell proliferation, differentiation and survival.
Cell cycle synchronization of leukemia inhibitory factor (LIF)-dependent porcine-induced pluripotent stem cells and the generation of cloned embryos.
Studied effect of recombinant porcine leukemia inhibitory factor on in vitro maturation of porcine oocytes; p-STAT3 (show STAT3 ELISA Kits) markedly increased in both cumulus cells and oocytes cultured in pLIF (show FTH1 ELISA Kits)-supplemented media.
LIF and IL-6 (show IL6 ELISA Kits) are important components of embryo-uterine interactions during early pregnancy in the pig, and may contribute to successful conceptus implantation.
Reprogramming pig fetal fibroblasts reveals a functional LIF signaling pathway.
favorable effect on litter size in pigs of the A allele for a SNP within the LIF gene
LIF (Leukemia inhibitory factor) mRNA was elevated in stented segments of coronary arteries; vascular smooth muscle cell proliferation was inhibited by LIF treatment in an in-vitro model of atherosclerosis
study found significant association of two diallelic polymorphisms in the porcine genes for leukaemia inhibitory factor (LIF) and retinol-binding protein 4 (RBP4 (show RBP4 ELISA Kits)) with number of piglets born alive (NBA) in two German pig lines
Studied the effects of leukemia inhibitory factor (LIF) on bovine oocyte maturation and early embryo development in vitro.
results suggest that leukemia inhibitory factor and macrophage-colony stimulating factor (show CSF2 ELISA Kits) are produced in the endometrium and may play different roles in early and mid-pregnancy
The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
, differentiation-stimulating factor
, D factor
, cholinergic differentiation factor
, differentiation inhibitory activity
, differentiation-inducing factor
, hepatocyte-stimulating factor III
, human interleukin in DA cells
, melanoma-derived LPL inhibitor
, leukemia inhibitory factor (cholinergic differentiation factor)
, cholinergic neuronal differentiation factor
, leukemia inhibitory factor
, D-factor/LIF receptor
, LIF receptor
, leukemia inhibitory factor receptor alpha chain
, soluble differentiation-stimulating factor receptor