Browse our PTPN6 (PTPN6) ELISA Kits

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Protein-tyrosine Phosphatase 1C ELISA Kits (PTPN6)
On www.antibodies-online.com are 15 Protein-tyrosine Phosphatase 1C (PTPN6) ELISA Kits from 9 different suppliers available. Additionally we are shipping PTPN6 Antibodies (206) and PTPN6 Proteins (20) and many more products for this protein. A total of 249 PTPN6 products are currently listed.
Synonyms:
DRPLA, hcp, Hcph, HPTP1C, me, motheaten, PTP-1C, Ptp1C, Ptph6, SH-PTP1, SHP, Shp-1, SHP-1L, SHP1
list all ELISA KIts Gene Name GeneID UniProt
PTPN6 23957 Q62227
PTPN6 5777 P29350
PTPN6 116689 P81718

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PTPN6 (PTPN6) ELISA Kits by Reactivity

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More ELISA Kits for PTPN6 Interaction Partners

Mouse (Murine) Protein-tyrosine Phosphatase 1C (PTPN6) interaction partners

  1. These findings suggest that protein tyrosine phosphatase SHP-1 may act as a positive regulator of osteoblast differentiation through direct association with and dephosphorylation of GSK3beta (show GSK3b ELISA Kits).

  2. data establish SHP-1 as a critical player in setting the threshold downstream of TCR signaling and identify a novel function of SHP-1 as a regulator of T cell susceptibility to Treg-mediated suppression in vitro and in vivo

  3. human microbiota was able to reduce the levels of tauro-beta-muricholic acid and induce expression of FXR (show NR1H4 ELISA Kits) target genes Fgf15 and Shp (show LAMC1 ELISA Kits) in ileum after long-term colonization. We show that a human microbiota can change BA composition and induce FXR (show NR1H4 ELISA Kits) signaling in colonized mice, but the levels of secondary BAs produced are lower than in mice colonized with a mouse microbiota

  4. SHP (show LAMC1 ELISA Kits) and REV-ERBalpha (show NR1D1 ELISA Kits) play a critical role in controlling rhythmic CHOP (show DDIT3 ELISA Kits) expression in alcoholic fatty liver

  5. Results are consistent with predicted/observed reduction in the Lyn-SHIP-1-PTEN-SHP-1 axis function in B cells from systemic lupus

  6. our results suggest that SHP (show LAMC1 ELISA Kits) upregulation upon high-fat feeding leads to lipid accumulation, insulin (show INS ELISA Kits) resistance and inflammation in cardiomyocytes.

  7. Our data show that SHP1 is required for the survival of mature thymocytes and the generation of the functional T-cell repertoire, as its absence leads to a reduction in the numbers of CD4 (show CD4 ELISA Kits)(+) and CD8 (show CD8A ELISA Kits)(+) naive T cells in the peripheral lymphoid compartments.

  8. Our study suggests that metformin exerts its insulin sensitizing effects via inhibition of SHP-1 activity and expression.

  9. we found that THEMIS directly regulated the catalytic activity of the tyrosine phosphatase SHP-1.

  10. Mortality of SHP (show LAMC1 ELISA Kits)-/- mice after ethanol binge feeding was significantly reduced and Aldh2 (show ALDH2 ELISA Kits) mRNA level was higher. After an intoxicating dose of ethanol, SHP (show LAMC1 ELISA Kits)-/- mice exhibited faster blood ethanol clearance.

Human Protein-tyrosine Phosphatase 1C (PTPN6) interaction partners

  1. SHP1 DNA methylation (show HELLS ELISA Kits) in in patients with B cell non-Hodgkin lymphoma

  2. these results indicate that DNMT1 mediates aberrant methylation and silencing of SHP-1 gene in chronic myelogenous leukemia cells

  3. Results provide evidence that repression of SHP-1, SHP-2 (show PTPN11 ELISA Kits) and SOCS-1 (show SOCS1 ELISA Kits) gene expression in patient plasma cells supports the constitutive activation of the JAK (show JAK3 ELISA Kits)/STAT3 (show STAT3 ELISA Kits) pathway and probably leads to higher degrees of bone marrow invasion.

  4. we found that THEMIS directly regulated the catalytic activity of the tyrosine phosphatase SHP-1.

  5. Hyperglycemia induces SHP-1 promoter epigenetic modifications, causing its persistent expression and activity and leading to insulin (show INS ELISA Kits) resistance, podocyte dysfunction, and DN.

  6. Low SHP1 expression is associated with primary central nervous system lymphoma.

  7. study evaluated SHP1-P2 methylation levels in the lymph nodes of colorectal cancer (CRC) patients; hypothesized that SHP1-P2 methylation levels would be higher in metastatic lymph nodes

  8. Overexpression of SHP1 downregulates the JAK2 (show JAK2 ELISA Kits)/STAT3 (show STAT3 ELISA Kits) pathway to modulate various target genes and inhibit cell proliferation, migration, and invasion in gastric cancer cells.

  9. This study also found no correlation of SHP-1 expression at diagnosis with response to treatment, although a trend for lower SHP-1 expression was noted in the very small non-responders' group of the 3-month therapeutic milestone.

  10. SYK (show SYK ELISA Kits), LYN (show LYN ELISA Kits) and PTPN6 were markedly elevated in atherosclerotic plaques of carotid atherosclerosis patients.

PTPN6 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.

Alternative names and synonyms associated with PTPN6

  • protein tyrosine phosphatase, non-receptor type 6 (PTPN6) Elisa Kit
  • nuclear receptor subfamily 0, group B, member 2 (Nr0b2) Elisa Kit
  • protein tyrosine phosphatase, non-receptor type 6 (Ptpn6) Elisa Kit
  • DRPLA Elisa Kit
  • hcp Elisa Kit
  • Hcph Elisa Kit
  • HPTP1C Elisa Kit
  • me Elisa Kit
  • motheaten Elisa Kit
  • PTP-1C Elisa Kit
  • Ptp1C Elisa Kit
  • Ptph6 Elisa Kit
  • SH-PTP1 Elisa Kit
  • SHP Elisa Kit
  • Shp-1 Elisa Kit
  • SHP-1L Elisa Kit
  • SHP1 Elisa Kit

Protein level used designations for PTPN6

nuclear receptor subfamily 0 group B member 2 , orphan nuclear receptor SHP , small heterodimer partner , hematopoietic cell phosphatase , hematopoietic cell protein-tyrosine phosphatase , protein-tyrosine phosphatase 1C , protein-tyrosine phosphatase SHP-1 , tyrosine-protein phosphatase non-receptor type 6 , 70Z-SHP , PTP-1C , PTPTY-42 , SH-PTP1 , hemopoietic cell phosphatase , SH2 phosphatase 1 , dentatorubro-pallidoluysian atrophy protein , non-receptor type protein tyrosine phosphatase SHP1

GENE ID SPECIES
100052882 Equus caballus
23957 Mus musculus
5777 Homo sapiens
15170 Mus musculus
116689 Rattus norvegicus
486717 Canis lupus familiaris
100171389 Sus scrofa
100723417 Cavia porcellus
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