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Browse our PTPN6 (PTPN6) ELISA Kits

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Protein-tyrosine Phosphatase 1C ELISA Kits (PTPN6)
On are 12 Protein-tyrosine Phosphatase 1C (PTPN6) ELISA Kits from 7 different suppliers available. Additionally we are shipping PTPN6 Antibodies (179) and PTPN6 Proteins (18) and many more products for this protein. A total of 220 PTPN6 products are currently listed.
DRPLA, hcp, Hcph, HPTP1C, me, motheaten, PTP-1C, Ptp1C, Ptph6, SH-PTP1, SHP, Shp-1, SHP-1L, SHP1
list all ELISA KIts Gene Name GeneID UniProt
PTPN6 23957 Q62227
PTPN6 5777 P29350
PTPN6 116689 P81718

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PTPN6 (PTPN6) ELISA Kits by Reactivity

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More ELISA Kits for PTPN6 Interaction Partners

Mouse (Murine) Protein-tyrosine Phosphatase 1C (PTPN6) interaction partners

  1. In addition to their role in NK cell activation by hematopoietic cells, the SLAM-SAP-SHP1 pathways influence responsiveness toward nonhematopoietic targets by a process akin to NK cell 'education'.

  2. This study reveals SHP (show LAMC1 ELISA Kits) as a global transcriptional partner of SREBP-2 (show SREBF2 ELISA Kits) in regulation of sterol biosynthetic gene networks and provides a potential mechanism for cholesterol-lowering action of FGF19 (show FGF19 ELISA Kits).

  3. The prostate of mev/mev mice exhibits signs of aberrant differentiation and the resulting phenotype may be related to the loss of function of SHP-1. Prostatic anomalies in these mice affect, together with defects in sperm maduration, for their sterility.

  4. These studies reveal critical pathways controlled by SHP-1 in oligodendrocytes that relate to susceptibility of SHP-1-deficient mice to both developmental defects in myelination and to inflammatory demyelinating diseases

  5. Our results suggest that SHP (show LAMC1 ELISA Kits) is required for both antidiabetic and hypolipidemic effects of TZDs in ob/ob mice through regulation of PPARgamma (show PPARG ELISA Kits) expression.

  6. These data are suggestive of a role for SHP (show LAMC1 ELISA Kits) in controlling NLRP3 (show NLRP3 ELISA Kits) inflammasome activation through a mechanism involving interaction with NLRP3 (show NLRP3 ELISA Kits) and maintenance of mitochondrial homeostasis.

  7. SHP-1 regulates Cbl-b-mediated T cell responses by controlling its tyrosine phosphorylation and ubiquitination

  8. The inhibitory activity of SHP-1 is needed for setting the threshold of natural killer cell reactivity.

  9. Shp1 signalling is required for the establishment of a life-long protective humoral immunity.

  10. Shp1 binds and controls PIPKIgamma activity and, thereby, modulates phosphatidylinositol (4,5)-bisphosphate levels and adhesion.

Human Protein-tyrosine Phosphatase 1C (PTPN6) interaction partners

  1. In addition to their role in NK cell activation by hematopoietic cells, the SLAM-SAP-SHP1 pathways influence responsiveness toward nonhematopoietic targets by a process akin to NK cell 'education'.

  2. A combination of sorafenib and SC-43 is a synergistic SHP-1 agonist duo (show KALRN ELISA Kits) which reduces tumor size and prolonged survival time.

  3. SHP-1 has a critical role in radioresistance, cell cycle progression, and senescence of nasopharyngeal carcinoma cells

  4. Data demonstrate for the first time that SHP1 methylation has high specificity for diagnosis of endometrial carcinoma, while CDH13 (show CDH13 ELISA Kits) promoter methylation plays a role in the earlier stage.

  5. MiR (show MLXIP ELISA Kits)-378g enhanced radiosensitivity partially by targeting SHP-1 in NPC (show NPC1 ELISA Kits) cells.

  6. Soluble egg antigens glycans are essential for induction of enhanced SOCS1 and SHP1 levels in dendritic cells via the mannose receptor.

  7. miR-4649-3p is downregulated in nasopharyngeal carcinoma cell lines accompanied with SHP-1 upregulation.

  8. Results show that dissociation of SHP-1 from spinophilin (show PPP1R9B ELISA Kits) is followed by an increase in the binding of spinophilin (show PPP1R9B ELISA Kits) to PP1 (show PPA1 ELISA Kits).

  9. Data show that SHP-1 promotes HIF-1alpha degradation under hypoxic conditions leading to a reduction in VEGF synthesis and secretion and impairing epithelial cells proliferation.

  10. Phosphorylation of ATR and CHK1 did not show significant differences in the three cell groups. Overexpression of SHP-1 in the CNE-2 cells led to radioresistance and the radioresistance was related to enhanced DNA DSB repair.

PTPN6 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.

Alternative names and synonyms associated with PTPN6

  • protein tyrosine phosphatase, non-receptor type 6 (PTPN6) Elisa Kit
  • nuclear receptor subfamily 0, group B, member 2 (Nr0b2) Elisa Kit
  • protein tyrosine phosphatase, non-receptor type 6 (Ptpn6) Elisa Kit
  • DRPLA Elisa Kit
  • hcp Elisa Kit
  • Hcph Elisa Kit
  • HPTP1C Elisa Kit
  • me Elisa Kit
  • motheaten Elisa Kit
  • PTP-1C Elisa Kit
  • Ptp1C Elisa Kit
  • Ptph6 Elisa Kit
  • SH-PTP1 Elisa Kit
  • SHP Elisa Kit
  • Shp-1 Elisa Kit
  • SHP-1L Elisa Kit
  • SHP1 Elisa Kit

Protein level used designations for PTPN6

nuclear receptor subfamily 0 group B member 2 , orphan nuclear receptor SHP , small heterodimer partner , hematopoietic cell phosphatase , hematopoietic cell protein-tyrosine phosphatase , protein-tyrosine phosphatase 1C , protein-tyrosine phosphatase SHP-1 , tyrosine-protein phosphatase non-receptor type 6 , 70Z-SHP , PTP-1C , PTPTY-42 , SH-PTP1 , hemopoietic cell phosphatase , SH2 phosphatase 1 , dentatorubro-pallidoluysian atrophy protein , non-receptor type protein tyrosine phosphatase SHP1

100052882 Equus caballus
23957 Mus musculus
5777 Homo sapiens
15170 Mus musculus
116689 Rattus norvegicus
486717 Canis lupus familiaris
100171389 Sus scrofa
100723417 Cavia porcellus
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