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Browse our Serotonin Receptor 1A Proteins (HTR1A)

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Serotonin Receptor 1A Proteins (HTR1A)
On are 8 Serotonin Receptor 1A (HTR1A) Proteins from 3 different suppliers available. Additionally we are shipping Serotonin Receptor 1A Antibodies (49) and Serotonin Receptor 1A Kits (4) and many more products for this protein. A total of 68 Serotonin Receptor 1A products are currently listed.
5-HT-1A, 5-HT-dro2A, 5-HT1A, 5-HT1ADro, 5-HT[1A]Dro, 5-HT[[1ADro]], 5-HT[[1A]], 5-HT[[1A]]DRO, 5HT-dro2A, 5HT-drp[[2A]], 5HT-R2A, 5ht1a, 5htdro2a, 5htr1a, 5HT[[1ADro]], adrb2rl1, adrbrl1, CG16720, d5-HT1A, Dm5HTdro2A, Dmel\\CG16720, DRO2A, G-21, Gpcr18, Htr1a, htr1a-A, PFMCD, RAT5HT1A
list all proteins Gene Name GeneID UniProt
HTR1A 15550 Q64264
HTR1A 3350 P08908
HTR1A 24473 P19327

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Serotonin Receptor 1A Proteins (HTR1A) by Origin

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More Proteins for Serotonin Receptor 1A Interaction Partners

Fruit Fly (Drosophila melanogaster) Serotonin Receptor 1A (HTR1A) interaction partners

  1. Activation of 5-HT1A and OAMB signaling in Insulin-producing cells generates differential effects on Dilp transcription, fly physiology, metabolism and social interactions.

  2. serotonin acts on brain IPCs via the 5-HT(1A) receptor, thereby affecting their activity and probably insulin (show INS Proteins) signaling

  3. Decrease in 5-HT(1A) receptor binding partly reflects hippocampal neuronal loss in temporal lobe epilepsy.

  4. The Drosophila serotonin receptor 1A has a role in promoting baseline sleep.

  5. study describes the influence of different 5-HT receptor (show HTR7 Proteins) subtypes on aggressive behaviors; activation of 5-HT(1A)-like receptors with 8-OH-DPAT increases overall aggression; 5-HT(1A)-like receptor manipulation primarily affects wing threats and fencing

Cow (Bovine) Serotonin Receptor 1A (HTR1A) interaction partners

  1. 5-HT(2) receptors are coupled to phospholipase C (show PLC Proteins) in bovine ciliary epithelium.

  2. the 5-HT(1A) receptor contains high and moderate affinity CaM (show KRIT1 Proteins) binding regions that may play important roles in receptor signaling and function

  3. analysis of eight bovine 5-HT receptor (show HTR7 Proteins) subtypes in brain, abomasum, and intestine by real-time RT-PCR

  4. role of cholesterol in solubilization of G-protein-coupled serotonin 1A receptors

  5. ligand binding function of the 5-HT(1A) receptor is a cholesterol-dependent phenomenon that is not related to the ability of cholesterol to modulate membrane order

Rhesus Monkey Serotonin Receptor 1A (HTR1A) interaction partners

  1. Increased levels of 5-HT1A receptor binding were seen in the raphe nuclei following chronic ethanol self-administration.

  2. Cimbi-36 is the first agonist radioligand suitable for examination of 5-HT2A receptors in the cortical regions and of 5-HT2C (show HTR2C Proteins) receptors in the choroid plexus of the primate brain.

  3. Significantly lower 5-HT1A binding is found in s-carrier subjects (5-HTTLPR (show SLC6A4 Proteins) genotype) in both cortical brain regions and the raphe nuclei.

  4. 5-HT1A receptor levels increase during development in the female brain from pre-to peripuberty.

  5. 5HT1A receptor may lose sensitivity to the suppressive effect of estradiol after 5 months, whereas the 5HT2C (show HTR2C Proteins) receptor increases, however, addition of progesterone in the EP5 regimen maintains the regulatory effects

Guinea Pig Serotonin Receptor 1A (HTR1A) interaction partners

  1. 5-HT(1A), SST (show SST Proteins)(1), and SST (show SST Proteins)(2) receptors mediate nonadrenergic IPSPs in the noncholinergic (VIP (show Vip Proteins)) secretomotor neurons of the submucous plexus of the guinea pig ileum.

  2. Since the 5-HT(1A) and 5-HT(2) agonists decreased and increased, respectively, the duration of TI, different serotonin receptor (show HTR1B Proteins) subtypes may play distinct roles in the modulation of TI in the guinea pig.

Mouse (Murine) Serotonin Receptor 1A (HTR1A) interaction partners

  1. Findings indicate that cannabidiol could represent a novel fast antidepressant drug, via enhancing both serotonergic and glutamate (show GRIN1 Proteins) cortical signalling through a 5-HT1A receptor (show CC2D1A Proteins)-dependent mechanism.

  2. The results of this study suggested that the hallucinogen action of 5-MeO-DMT is mediated by simultaneous alterations of the activity of cerebral cortex also supporting a role of 5-HT(1A)-R stimulation in V1 and PFC (show CFP Proteins).

  3. Results indicate that GIRK channels formed by GIRK2 (show KCNJ6 Proteins) subunits determine depression-related behaviors as well as basal and 5-HT1A receptor (show CC2D1A Proteins)-mediated dorsal raphe neuronal activity

  4. Results indicate that postsynaptic 5-HT1A receptors exert a modulatory function in food intake in free-feeding and fasted mice, which for the first time shows an involvement of postsynaptic 5-HT1A receptors in feeding behavior

  5. 5HT1A receptors regulate glucose through brain mechanisms, but not through regulation of the hypophyseal-pituitary axis.

  6. It indicated that Correlation between nAChalpha4-, 5-HT1A- and 5-HT7 (show HTR7 Proteins)-containing receptors and latencies on day 16 may point to a probable link in extinction mechanisms.

  7. There is enhanced capacity of 5-HT1A receptors to inhibit neurons in the prefrontal cortex in SERT (show SLC6A4 Proteins)-knockout mice.

  8. 5-HT1A and 5-HT2A receptors are able to modulate each other functional activity by means of bilateral functional cross-talk.

  9. impact of the 5-HT2A and the 5-HT1A receptor (show CC2D1A Proteins) for different serotonin syndrome-like responses

  10. Results showed a difference in food intake between WT and 5-HT1A-R KO mice with differential expression of POMC (show POMC Proteins), CART and GABAA (show GABRg1 Proteins) beta2. A difference in body weight between WT and KO mice was associated with different expression levels of CART and GABAA (show GABRg1 Proteins) beta2.

Human Serotonin Receptor 1A (HTR1A) interaction partners

  1. A single-nucleotide polymorphism of the serotonin 1a receptor gene (HTR1A) has been designated rs6295.28 and found to be overrepresented in suicide and associated with a decreased responsiveness to antidepressants.

  2. Results reported here strongly support the role of 5-HT1A partial agonism as a means of restoring cognitive function following subchronic treatment with an NMDAR (show GRIN1 Proteins) non-competitiave antagonist

  3. This study demonistrated that cue learning, trait anxiety and genetic variability in 5-HTR1A are involved in the regulation of contextual anxiety.

  4. epistatic effects of 5HTR1A and 5HTR2A genes on suicidal behaviour were not significant

  5. Our findings provide supportive evidence that genetic polymorphisms in SLC6A4 and HTR1A may influence the risk of SZ in Han Chinese individuals

  6. IPO11 (show IPO11 Proteins)-HTR1A is a significant risk gene region for attention deficit hyperactivity disorder in Caucasians.

  7. Also patients with a higher level of alexithymia and the HTR1A-G gene variant are more vulnerable to experiencing IFN-induced depressive symptoms

  8. No significant association was found between SNPs in HTR1A (rs6295), HTR2A (rs6311 and rs6313) and SLC6A4 (show SLC6A4 Proteins) and response to escitalopram in patients with major depressive disorder

  9. The data on the distribution of allele and genotype frequencies of the HTR1A, HTR2A, and HTR1B (show HTR1B Proteins) genes can be used to determine the associations of the identified markers with various forms of human aggressive behavior.

  10. Studied site-directed mutants of the HTR1A receptor in application of yeast-based signaling sensor.

Horse (Equine) Serotonin Receptor 1A (HTR1A) interaction partners

  1. Polymorphism in the serotonin receptor 1A gene may affect tractability in horses, with the effect partially different depending on sex.

Serotonin Receptor 1A (HTR1A) Protein Profile

Protein Summary

This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers.

Alternative names and synonyms associated with Serotonin Receptor 1A (HTR1A)

  • Serotonin receptor 1A (5-HT1A)
  • 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A)
  • 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled (HTR1A)
  • 5-hydroxytryptamine (serotonin) receptor 1A a (htr1aa)
  • 5-hydroxytryptamine (serotonin) receptor 1A (Htr1a)
  • 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled (Htr1a)
  • 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled (htr1a)
  • 5-HT-1A protein
  • 5-HT-dro2A protein
  • 5-HT1A protein
  • 5-HT1ADro protein
  • 5-HT[1A]Dro protein
  • 5-HT[[1ADro]] protein
  • 5-HT[[1A]] protein
  • 5-HT[[1A]]DRO protein
  • 5HT-dro2A protein
  • 5HT-drp[[2A]] protein
  • 5HT-R2A protein
  • 5ht1a protein
  • 5htdro2a protein
  • 5htr1a protein
  • 5HT[[1ADro]] protein
  • adrb2rl1 protein
  • adrbrl1 protein
  • CG16720 protein
  • d5-HT1A protein
  • Dm5HTdro2A protein
  • Dmel\\CG16720 protein
  • DRO2A protein
  • G-21 protein
  • Gpcr18 protein
  • Htr1a protein
  • htr1a-A protein
  • PFMCD protein
  • RAT5HT1A protein

Protein level used designations for Serotonin Receptor 1A Proteins (HTR1A)

5-HT1A-PB , CG16720-PB , serotonin receptor 1A , serotonin receptor 2A , serotonin-receptor-2A , 5-hydroxytryptamine receptor 1A , 5-hydroxytryptamine (serotonin) receptor 1A , 5-HT1A , 5-HT-1A , 5-HT1A receptor , G-protein coupled receptor 18 , 5-HT1a receptor , guanine nucleotide-binding regulatory protein-coupled receptor , X5-HT1A , Serotonin receptor 1A

37196 Drosophila melanogaster
407137 Bos taurus
431581 Gallus gallus
694991 Macaca mulatta
100001828 Danio rerio
100008780 Oryctolagus cuniculus
100286860 Sus scrofa
100301563 Cavia porcellus
15550 Mus musculus
3350 Homo sapiens
24473 Rattus norvegicus
487230 Canis lupus familiaris
100009683 Equus caballus
378605 Xenopus laevis
471533 Pan troglodytes
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