Browse our Serotonin Receptor 2B Proteins (HTR2B)

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Serotonin Receptor 2B Proteins (HTR2B)
On www.antibodies-online.com are 7 Serotonin Receptor 2B (HTR2B) Proteins from 3 different suppliers available. Additionally we are shipping Serotonin Receptor 2B Antibodies (34) and many more products for this protein. A total of 43 Serotonin Receptor 2B products are currently listed.
Synonyms:
5-HT(2B), 5-HT2B, 5ht2b, 5htr2b, AJ012488, AV377389, HTR2B, zgc:194094, zgc:194119
list all proteins Gene Name GeneID UniProt
HTR2B 15559 Q02152
HTR2B 3357 P41595
Rat HTR2B HTR2B 29581 P30994

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Serotonin Receptor 2B Proteins (HTR2B) by Origin

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More Proteins for Serotonin Receptor 2B Interaction Partners

Cow (Bovine) Serotonin Receptor 2B (HTR2B) interaction partners

  1. 5-HT(2) receptors are coupled to phospholipase C (show PLC Proteins) in bovine ciliary epithelium.

Mouse (Murine) Serotonin Receptor 2B (HTR2B) interaction partners

  1. Our results indicate that prolonged Htr2b activation in murine beta-cells decreases glucose-stimulated insulin secretion and mitochondrial activity by mechanisms likely dependent on enhanced PGC1a/PPARygexpression.

  2. heterodimerization with 5-HT2C (show HTR2C Proteins) receptors does not alter 5-HT2C (show HTR2C Proteins) Galphaq (show GNAQ Proteins)-dependent inositol phosphate signaling, 5-HT2A or 5-HT2B receptor-mediated signaling was totally blunted. This feature can be explained by a dominance of 5-HT2C (show HTR2C Proteins) on 5-HT2A and 5-HT2B receptor binding; in 5-HT2C (show HTR2C Proteins)-containing heterodimers, ligands bind and activate the 5-HT2C (show HTR2C Proteins) protomer exclusively.

  3. Activation of 5-HT2B receptors stimulates GSIS in beta cells by triggering downstream changes in cellular Ca(2 (show CA2 Proteins)+) flux that enhance mitochondrial metabolism.

  4. Heritable pulmonary arterial hypertension (PAH) results from increased SRC activation, cellular contraction, and vascular resistance, but antagonism of HTR2B prevents SRC phosphorylation and development of PAH.

  5. Results support that the abnormal organization of retinal projections in Htr2B-/- animals is due to the lack of 5-HT (show DDC Proteins) activation of 5-HT2B receptors in postnatal microglial cells

  6. 5-HT2B stimulation has no effectin neurite outgrowth.

  7. the serotonin transporter (show SLC6A4 Proteins) has a role in regulating clearance of apoptotic cells through neuroendocrine signaling

  8. Serotonin 2B receptor (5-HT2B R) signals through prostacyclin and PPAR (show PPARA Proteins)-ss/delta in osteoblasts.

  9. the results suggested that RKT improves the decrease in food intake after novelty stress probably via 5-HT(2B) receptor antagonism of isoliquiritigenin contained in RKT.

  10. Augmented contractile properties of arteries in a model of type 2 diabetes mellitus are not due to changes in 5HT (show DDC Proteins)(2A)/5HT (show DDC Proteins)(2B) receptors.

Human Serotonin Receptor 2B (HTR2B) interaction partners

  1. Study describes the crystal structure of Lysergic acid diethylamide (LSD (show DNASE1L3 Proteins)) in complex with the human serotonin receptor (show HTR1B Proteins) 5-HT2B. The complex reveals conformational rearrangements to accommodate LSD (show DNASE1L3 Proteins), providing a structural explanation for the conformational selectivity of LSD's key diethylamide moiety.

  2. heterodimerization with 5-HT2C (show HTR2C Proteins) receptors does not alter 5-HT2C (show HTR2C Proteins) Galphaq (show GNAQ Proteins)-dependent inositol phosphate signaling, 5-HT2A or 5-HT2B receptor-mediated signaling was totally blunted. This feature can be explained by a dominance of 5-HT2C (show HTR2C Proteins) on 5-HT2A and 5-HT2B receptor binding; in 5-HT2C (show HTR2C Proteins)-containing heterodimers, ligands bind and activate the 5-HT2C (show HTR2C Proteins) protomer exclusively.

  3. The 5-HT2B receptor may contribute to the regulation of human glucagon (show GCG Proteins) and glucose homeostasis and the interplay between glucagon (show GCG Proteins) and insulin (show INS Proteins) secretion.

  4. Authors hypothesize that HTR2B expression in the infarcted territory may render degenerating neurons susceptible to attack by activated microglia and thus aggravate the consequences of stroke.

  5. Activation of 5-HT2B receptors stimulates GSIS in beta cells by triggering downstream changes in cellular Ca(2 (show CA2 Proteins)+) flux that enhance mitochondrial metabolism.

  6. the 5-HT2B receptor limits degeneration of spinal cord mononuclear phagocytes, most likely microglia, and slows disease progression in amyotrophic lateral sclerosis

  7. Studies have found that the HTR2B Q20* connected with impulsive behavior and cognitive impulsivity.

  8. Data indicate that hydrogen bonding interactions with Ser3.36 and Thr3.37 were important for isoflurane binding with the 5HT2B receptor.

  9. results of the present study suggest that the HTR2B polymorphism is not likely to be associated with personality traits, including novelty seeking and impulsivity.

  10. Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptors.

Pig (Porcine) Serotonin Receptor 2B (HTR2B) interaction partners

  1. distribution of serotonin 2B receptor is species different in the pig small intestine and the intensity of serotonin 2B receptor becomes stronger as the small intestine matures

Serotonin Receptor 2B (HTR2B) Protein Profile

Protein Summary

This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.

Alternative names and synonyms associated with Serotonin Receptor 2B (HTR2B)

  • 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B)
  • 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled (HTR2B)
  • 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled (htr2b)
  • 5-hydroxytryptamine (serotonin) receptor 2B (LOC100228803)
  • 5-hydroxytryptamine (serotonin) receptor 2B (Htr2b)
  • 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled (Htr2b)
  • 5-HT(2B) protein
  • 5-HT2B protein
  • 5ht2b protein
  • 5htr2b protein
  • AJ012488 protein
  • AV377389 protein
  • HTR2B protein
  • zgc:194094 protein
  • zgc:194119 protein

Protein level used designations for Serotonin Receptor 2B Proteins (HTR2B)

5-hydroxytryptamine (serotonin) receptor 2B , 5-hydroxytryptamin receptor , 5-hydroxytryptamine receptor 2B , 5HT2B receptor , serotonin receptor 2B , 5-hydroxytryptamine receptor 2B-like , 5-HT-2B , 5-HT-2F , NP75 protein , 5-HT2B serotonin receptor , 5-HT 2B receptor , 5-hydroxytryptamine 2B receptor , 5-hydroxytryptamine receptor 2B variant b , 5-HT2B , stomach fundus serotonin receptor , serotonin 2B receptor

GENE ID SPECIES
395581 Gallus gallus
403881 Canis lupus familiaris
407135 Bos taurus
711808 Macaca mulatta
737647 Pan troglodytes
751784 Danio rerio
100014874 Monodelphis domestica
100077777 Ornithorhynchus anatinus
100228803 Taeniopygia guttata
100394497 Callithrix jacchus
100466077 Ailuropoda melanoleuca
15559 Mus musculus
100135546 Cavia porcellus
3357 Homo sapiens
29581 Rattus norvegicus
396837 Sus scrofa
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