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Browse our Serotonin Receptor 6 Proteins (HTR6)

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Serotonin Receptor 6 Proteins (HTR6)
On are 4 Serotonin Receptor 6 (HTR6) Proteins from 1 different suppliers available. Additionally we are shipping Serotonin Receptor 6 Antibodies (17) and many more products for this protein. A total of 22 Serotonin Receptor 6 products are currently listed.
5-HT6, 5-HT6R
list all proteins Gene Name GeneID UniProt
HTR6 15565 Q9R1C8
HTR6 3362 P50406
Rat HTR6 HTR6 64354 P31388

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Serotonin Receptor 6 Proteins (HTR6) by Origin

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More Proteins for Serotonin Receptor 6 Interaction Partners

Mouse (Murine) Serotonin Receptor 6 (HTR6) interaction partners

  1. SNX14 (show SNX14 Proteins) is a dual endogenous negative regulator in 5-HT6R-mediated signaling pathway.

  2. Constitutive expression of 5-HT6R controls pyramidal neuron migration through an agonist-independent mechanism that requires Cdk5 (show CDK5 Proteins) activity.

  3. Knockdown of MAO-A (show MAOA Proteins) expression in embryos induces high serotonin levels and abnormal brain development, which can be rescued by inactivation of serotonin receptor-6.

  4. Coexpression of 5HT6 with adenylyl cyclase type III (show ADCY3 Proteins) normalizes cilia structure and restores dendrite outgrowth.

  5. Serotonergic stimulation of 5-HT6 serotonin receptors augments extrapyramidal motor symptoms; antagonism of 5-HT6 receptors alleviates the symptoms.

  6. 5-HT6 receptors were expressed in embryonic mouse cortical interneurons and that 5-HT6 receptor activation decreased interneuron migration, whereas 5-HT6 receptor blockade prevented the migratory effects induced by 5-HT (show DDC Proteins).

Human Serotonin Receptor 6 (HTR6) interaction partners

  1. that HTR6 plays an important role in modulating seizure activity and that the blockade of the 5-HT6 receptor/mTOR (show FRAP1 Proteins) pathway could be a potential therapeutic target for epilepsy treatment

  2. Studies indicate that serotonin 5-HT6 receptor (5-HT6R) has been proposed as a promising drug target for cognition enhancement in Alzheimer's disease (AD).

  3. [review] Controlling the activity of 5-HTR6 receptors seems to provide benefits by alleviating cognitive impairments.

  4. Data indicate that hydrogen-bond formation of a methoxy or hydroxy group is not important for binding at the 5-HT6 receptor.

  5. The human cloned 5-HT6 receptor is stably transfected in HeLa cells.

  6. When expressed in pyramidal neuron progenitors, serotonin receptor (show HTR1B Proteins) 5-HT6 transgene decreases the migration speed of cortical pyramidal neurons, thereby affecting a fundamental step in the assembly of neural circuits.

  7. These observations suggest that recruitment of mTOR (show FRAP1 Proteins) by prefrontal 5-HT(6) receptors contributes to the perturbed cognition in schizophrenia, offering new vistas for its therapeutic control.

  8. There was a statistically significant difference in semantic memory scores among the three genotype groups of T267C in 5-HT6.

  9. present findings showed the presence of a higher density of 5-HT(6) receptors, as labeled by [(125)I]SB-258585, in striatum than in hippocampus and prefrontal cortex, and specifically within the neuronal body

  10. results indicate that tagging SNPs in HTR6 may not play a role in the pathophysiology of schizophrenia.

Serotonin Receptor 6 (HTR6) Protein Profile

Protein Summary

This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that function as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity).

Alternative names and synonyms associated with Serotonin Receptor 6 (HTR6)

  • 5-hydroxytryptamine (serotonin) receptor 6 (Htr6)
  • 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled (HTR6)
  • 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled (Htr6)
  • 5-HT6 protein
  • 5-HT6R protein

Protein level used designations for Serotonin Receptor 6 Proteins (HTR6)

5-HT-6 , 5-hydroxytryptamine receptor 6 , serotonin receptor 6 , 5-HT6 , ST-B17 , 5-alpha-hydroxytryptamine receptor 6

15565 Mus musculus
3362 Homo sapiens
64354 Rattus norvegicus
469199 Pan troglodytes
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