Browse our anti-Cullin 2 (CUL2) Antibodies

On are 128 Cullin 2 (CUL2) Antibodies from 25 different suppliers available. Additionally we are shipping Cullin 2 Proteins (5) and Cullin 2 Kits (3) and many more products for this protein. A total of 146 Cullin 2 products are currently listed.
1300003D18Rik, 4932411N15Rik, AI327301, ATCUL2, cul2, cullin-2, cullin 2, F22D16.2, F22D16_2, fj48a06, LOC100221330, mKIAA4106, wu:fj48a06
list all antibodies Gene Name GeneID UniProt
CUL2 8453 Q13617
CUL2 71745 Q9D4H8
CUL2 361258  

Most Popular Reactivities for anti-Cullin 2 (CUL2) Antibodies

anti-Human Cullin 2 Antibodies:

anti-Mouse (Murine) Cullin 2 Antibodies:

anti-Rat (Rattus) Cullin 2 Antibodies:

All available anti-Cullin 2 Antibodies

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More Antibodies against Cullin 2 Interaction Partners

Human Cullin 2 (CUL2) interaction partners

  1. misfolded TDP-43 (show TARDBP Antibodies) is cleared by VHL (show VHL Antibodies)/CUL2 in a step-wise manner via fragmentation.

  2. Cullins are a family of NEDD8 (show NEDD8 Antibodies) targets important in the stabilization and degradation of proteins, such as hypoxia-inducible factor (HIF1A (show HIF1A Antibodies)), via Cullin-2.

  3. Nevertheless, the identification of the Cul2 box may allow prediction of Cullin specificity for all E4orf6-containing Adenoviridae.

  4. a novel link between the oncoprotein PRAME (show PRAME Antibodies) and the conserved EKC (show TAC4 Antibodies) complex

  5. Study finds that UBXN7 over-expression converts CUL2 to its neddylated form and causes the accumulation of non-ubiquitylated HIF1alpha (show HIF1A Antibodies).

  6. The authors applied protein-complex purification strategies and identified PRAME (show PRAME Antibodies) as a substrate recognition subunit of a Cullin2-based E3 ubiquitin ligase (show MUL1 Antibodies).

  7. The data suggest that neither HIF1alpha (show HIF1A Antibodies) nor CUL2 mutation may play a central role in HIF1alpha (show HIF1A Antibodies) activation in gastric, colorectal, breast, lung and hepatocellular carcinomas, and acute leukemias.

  8. Cullin selection is determined by specific Elongin C (show TCEB1 Antibodies) and Skp1 (show SKP1 Antibodies) sequences

  9. the HPV16 E7-associated cullin 2 ubiquitin ligase complex contributes to aberrant degradation of the pRB (show RB1 Antibodies) tumor suppressor in HPV16 E7-expressing cells.

  10. CUL2 is required for normal vasculogenesis, at least in part mediated by its regulation of HIF-mediated transcription.

Cow (Bovine) Cullin 2 (CUL2) interaction partners

  1. Authors show that bovine immunodeficiency virus Vif (show BTG1 Antibodies) interacts with Cullin 2 (CUL2), ELOB (show TCEB2 Antibodies)/C, and RBX1 (show RBX1 Antibodies), but not with CBF-beta (show CBFB Antibodies) or CUL5 (show CUL5 Antibodies), to form a CRL2 (show DAND5 Antibodies) E3 ubiquitin ligase (show MUL1 Antibodies) and degrade the restrictive bovine APOBEC3 (show APOBEC3F Antibodies) proteins (A3Z2Z3 and A3Z3 (show APOBEC3F Antibodies)).

Caenorhabditis elegans (C. elegans) Cullin 2 (CUL2) interaction partners

  1. CUL-2(LRR-1 (show LRR1 Antibodies)) and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis.

  2. CUL-2 RING E3 ubiquitin-ligase (show MUL1 Antibodies) acts at multiple levels to control germline development; CUL-2 may similarly regulate germline development in other organisms as well.

  3. Results indicate that LRR-1 (show LRR1 Antibodies) acts as a nuclear substrate-recognition subunit of a Cullin 2-RING E3 ligase complex (CRL2 (show DAND5 Antibodies)(LRR-1 (show LRR1 Antibodies))), which ensures DNA replication integrity.

  4. The C. elegans p97/CDC-48 (show vcp Antibodies)-UFD-1 (show UFD1L Antibodies)-NPL-4 complex controls the sperm-oocyte switch by regulating CUL-2-mediated TRA-1A proteasome degradation.

  5. segregation of the germ plasm involves both stabilization of germline proteins in the germ line and cullin-dependent degradation in the soma

  6. Results establish that zyg-11 and the cullin cul-2 promote the metaphase-to-anaphase transition and M phase exit at meiosis II in Caenorhabditis elegans.

  7. Data show that inactivation of ZYG-11 produces meiotic and polarity reversal defects similar to those observed in CUL-2 mutants, suggesting that the two proteins function in the same pathways.

  8. oocyte maturation from pachytene exit and MPK-1 (show MAPK1 Antibodies) activation are redundantly controlled by the RBX-2-CUL-5 (show CUL5 Antibodies)- and RBX-1 (show RBX1 Antibodies)-CUL-2-based complexes.

  9. TRA-1 is regulated by degradation mediated by a CUL-2-based ubiquitin ligase complex

  10. Fem-1 protein is a substrate-specific adaptor for a CUL-2-based ubiquitin ligase.

Cullin 2 (CUL2) Antigen Profile

Antigen Summary

Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).

Alternative names and synonyms associated with Cullin 2 (CUL2)

  • Cullin-2 (cul2) antibody
  • cullin 2 (CUL2) antibody
  • cullin-2 (PTRG_05231) antibody
  • cullin-2 (cul-2) (Smp_079740) antibody
  • cullin 2 (cul2) antibody
  • cullin 2 (LOC100221330) antibody
  • cullin 2 (Cul2) antibody
  • Protein CUL-2 (cul-2) antibody
  • 1300003D18Rik antibody
  • 4932411N15Rik antibody
  • AI327301 antibody
  • ATCUL2 antibody
  • cul2 antibody
  • cullin-2 antibody
  • cullin 2 antibody
  • F22D16.2 antibody
  • F22D16_2 antibody
  • fj48a06 antibody
  • LOC100221330 antibody
  • mKIAA4106 antibody
  • wu:fj48a06 antibody

Protein level used designations for anti-Cullin 2 (CUL2) Antibodies

Cullin-2 , CUL-2 , cullin-2 , cullin-2 (cul-2) , cullin 2 , cullin-2-like

100195615 Salmo salar
100174361 Pongo abelii
6343481 Pyrenophora tritici-repentis Pt-1C-BFP
8345692 Schistosoma mansoni
336088 Danio rerio
420467 Gallus gallus
450399 Pan troglodytes
698384 Macaca mulatta
100221330 Taeniopygia guttata
100395340 Callithrix jacchus
100550749 Meleagris gallopavo
8453 Homo sapiens
71745 Mus musculus
361258 Rattus norvegicus
477952 Canis lupus familiaris
535219 Bos taurus
379729 Xenopus laevis
839415 Arabidopsis thaliana
176806 Caenorhabditis elegans
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