Browse our FAM33A Proteins (FAM33A)

Full name:
Spindle and Kinetochore-Associated Protein 2 Proteins (FAM33A)
On are 6 Spindle and Kinetochore-Associated Protein 2 (FAM33A) Proteins from 2 different suppliers available. Additionally we are shipping FAM33A Antibodies (36) and FAM33A Kits (2) and many more products for this protein. A total of 47 FAM33A products are currently listed.
1110001A07Rik, C78640, fam33a, RGD1307084
list all proteins Gene Name GeneID UniProt
FAM33A 348235 Q8WVK7
FAM33A 66140 Q9CR46
FAM33A 287598 Q5I0J4

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FAM33A Proteins (FAM33A) by Origin

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More Proteins for FAM33A Interaction Partners

Human Spindle and Kinetochore-Associated Protein 2 (FAM33A) interaction partners

  1. p53 (show TP53 Proteins) negatively regulates the expression of the PRR11-SKA2 bidirectional transcription unit through NF-Y, suggesting that the inability to repress the PRR11-SKA2 bidirectional transcription unit after loss of p53 (show TP53 Proteins) might contribute to tumorigenesis.

  2. these data establish the importance of SKA2 for cortisol stress responsivity and the development of post-traumatic stress disorder and provide further evidence that SKA2 is a promising biomarker for stress-related disorders including PTSD.

  3. Results suggest that DNA methylation (show HELLS Proteins)(adj) of SKA2 in blood indexes stress-related psychiatric phenotypes and neurobiology, pointing to its potential value as a biomarker of stress exposure and susceptibility.

  4. DNA methylation (show HELLS Proteins) of the SKA2 gene has been implicated as a biomarker of suicide risk and posttraumatic stress disorder.

  5. SKA2 is hypothesized to reduce the ability to suppress cortisol following stress.

  6. PRR11-SKA2 bidirectional transcription unit, which is a novel direct target of NF-Y, is essential for the accelerated proliferation and motility of lung cancer cells

  7. SKA2 significantly interacted with anxiety and stress to explain about 80% of suicidal behavior and progression from suicidal ideation to suicide attempt.SKA2 is a novel genetic and epigenetic marker involved in the etiology of suicide, suicidal behaviors

  8. The structure of the Ska core complex is a W-shaped dimer of coiled coils, formed by intertwined interactions between Ska1 (show SKA1 Proteins), Ska2, and Ska3 (show SKA3 Proteins).

  9. Data suggest that Aurora B phosphorylation antagonizes the interaction between the Ska1-3 complex and the KMN network, thereby controlling Ska recruitment to KTs and stabilization of KT-MT attachments.

  10. blocking of miR (show MLXIP Proteins)-301 in A549 cells leads to a decrease in the expression of the host gene, ska2.

Mouse (Murine) Spindle and Kinetochore-Associated Protein 2 (FAM33A) interaction partners

FAM33A Protein Profile

Protein Summary

Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for ska1 localization (By similarity).

Alternative names and synonyms associated with FAM33A

  • spindle and kinetochore associated complex subunit 2 (SKA2)
  • spindle and kinetochore associated complex subunit 2 (Ska2)
  • Spindle and kinetochore-associated protein 2 (ska2)
  • 1110001A07Rik protein
  • C78640 protein
  • fam33a protein
  • RGD1307084 protein

Protein level used designations for FAM33A

family with sequence similarity 33, member A , spindle and KT (kinetochore) associated 2 , spindle and kinetochore-associated protein 2 , Protein FAM33A

348235 Homo sapiens
66140 Mus musculus
615847 Bos taurus
287598 Rattus norvegicus
100195579 Salmo salar
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