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Browse our ATF2 Proteins (ATF2)

Full name:
Activating Transcription Factor 2 Proteins (ATF2)
On are 16 Activating Transcription Factor 2 (ATF2) Proteins from 8 different suppliers available. Additionally we are shipping ATF2 Antibodies (575) and ATF2 Kits (54) and many more products for this protein. A total of 673 ATF2 products are currently listed.
Atf-2, ATF1, ATF2, atf2-A, atf2l, CG3749, CG12850, CG30420, CHN1, CRE-BP, CRE-BP1, Creb2, D18875, D130078H02Rik, dATF-2, DmelCG30420, HB16, HFB1-GDNF, HSCR3, mXBP, Tg(Gzma-Klra1)7Wum, TREB7
list all proteins Gene Name GeneID UniProt
ATF2 1386 P15336
ATF2 11909 P16951
ATF2 81647 Q00969

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ATF2 Proteins (ATF2) by Origin

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Top referenced ATF2 Proteins

  1. Human ATF2 Protein expressed in Baculovirus infected Insect Cells - ABIN2004411 : Sano, Harada, Tashiro, Gotoh-Mandeville, Maekawa, Ishii: ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling. in The Journal of biological chemistry 1999 (PubMed)

More Proteins for ATF2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Activating Transcription Factor 2 (ATF2) interaction partners

  1. This study reveals that Drosophila ATF-2 (dATF-2) is required for heterochromatin assembly, whereas the stress-induced phosphorylation of dATF-2, via Mekk1 (show MAP3K1 Proteins)-p38 (show MAPK14 Proteins), disrupts heterochromatin.

  2. ATF-2 is critical for regulation of fat metabolism.

  3. dATF-2 is activated by the locomotor while it increases sleep, suggesting a role for dATF-2 as a regulator to connect sleep with locomotion.

Human Activating Transcription Factor 2 (ATF2) interaction partners

  1. CARMA1 (show CARD11 Proteins)- and MyD88 (show MYD88 Proteins)-dependent activation of Jun (show JUN Proteins)/ATF-type AP-1 (show FOSB Proteins) complexes is a hallmark of ABC (show ABCB6 Proteins) diffuse large B-cell lymphomas.

  2. Increased plasma levels of GDNF (show GDNF Proteins) were found in untreated attention deficit hyperactivity disorder patients.

  3. More terminally differentiated human odontoblasts was ATF-2 positive, as compared to pulpal fibroblasts at various stages of differentiation: ATF-2 is more associated with cell survival rather than cell proliferation.

  4. GDNF (show GDNF Proteins) levels were lower in the ECT responders compared with pre-ECT levels

  5. The GDNF (show GDNF Proteins) polymorphism rs3096140 is associated with Tourette syndrome.

  6. GDNF (show GDNF Proteins) levels were significantly higher in mania and lower in schizophrenia compared to healthy controls. BDNF (show BDNF Proteins) levels were negatively correlated to illness severity scores in affective episodes

  7. Data indicate that glial cell-derived neurotrophic factor (GDNF (show GDNF Proteins)) was down-regulated in the medullary sponge kidney (MSK) cells.

  8. Osteogenic features of MSCs from ossification of yellow ligament patients are promoted by un-methylated GDNF (show GDNF Proteins).

  9. The glial cell line-derived neurotrophic factor(GDNF (show GDNF Proteins))-induced growth and differentiation of cultured enteric neurons is paralleled by increased expression of SNAP-25 (show SNAP25 Proteins) and formation of synaptic vesicles reflecting enhanced synaptogenesis.

  10. improvement in behavioral performance (open-field and grip-strength tests), as well as increased life-span was observed in rodents treated with NCAM (show NCAM1 Proteins)-VEGF (show VEGFA Proteins) or NCAM (show NCAM1 Proteins)-GDNF (show GDNF Proteins) co-transfected cells

Mouse (Murine) Activating Transcription Factor 2 (ATF2) interaction partners

  1. These data identified a role for ATF2 in regulating melanocyte responses.

  2. suppression of tumorigenesis by JNK (show MAPK8 Proteins) requires ATF2.

  3. Taken together, our observations indicated that SOCS2 (show SOCS2 Proteins) could suppress myotube formation, act as an anti-regulator of mitochondria biogenesis via inhibiting p38 MAPK (show MAPK14 Proteins) signal pathway.

  4. ATF2 is an important transcriptional factor relating to inflammation through the suppression of ATF3 (show ATF3 Proteins) in M1 macrophages of White adipose tissue.

  5. ATF-2 plays critical roles for proper expression of tyrosine hydroxylase (show TH Proteins) gene and for neurite extension of catecholaminergic neurons, possibly through repressor-like action.

  6. these studies show that the IL-1beta (show IL1B Proteins)-induced increase in intestinal tight junction permeability was regulated by p38 (show CRK Proteins) kinase activation of ATF-2 and by ATF-2 regulation of MLCK (show MYLK Proteins) gene activity

  7. The ATF2 represses renin (show REN Proteins) expression by drifting the transcriptional control of renin (show REN Proteins) gene away from CRE-binding protein (CREB (show CREB1 Proteins)).

  8. ATF2 has a critical role in limiting the activities of stress kinases JNK (show MAPK8 Proteins) and p38 (show CRK Proteins) which are potent inducers of cell death in the CNS

  9. ATF2 interacts with beta-cell-enriched transcription factors, MafA (show MAFA Proteins), Pdx1 (show PDX1 Proteins), and beta2, and activates insulin (show INS Proteins) gene transcription.

  10. MITF (show MITF Proteins) is downregulated by ATF2 in the skin of Atf2-/- mice, in primary human melanocytes, and in melanoma cell lines.

Xenopus laevis Activating Transcription Factor 2 (ATF2) interaction partners

  1. ATF2-based luciferase reporter to monitor non-canonical Wnt (show WNT2 Proteins) signaling in Xenopus embryos.

Cow (Bovine) Activating Transcription Factor 2 (ATF2) interaction partners

  1. Ang II (show AGT Proteins) increases endothelial arginase activity/expression through a p38 MAPK (show MAPK14 Proteins)/ATF-2 pathway leading to reduced endothelial NO production

  2. Data indicate that Ser738/742-to-glutamate (show GRIN2A Proteins) protein kinase D (show PRKD1 Proteins) mutant increased AngII-induced CREB (show CREB1 Proteins) protein and activating transcription factor 2 phosphorylation, and phospho-CREB (show CREB1 Proteins) binding to the steroidogenic acute regulatory protein (show STAR Proteins) promoter.

ATF2 Protein Profile

Protein Summary

This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease.

Alternative names and synonyms associated with ATF2

  • activating transcription factor 2 (ATF2)
  • Activating transcription factor-2 (Atf-2)
  • activating transcription factor 2 (Atf2)
  • activating transcription factor 2 (atf2)
  • activating transcription factor 2 (LOC100355367)
  • glial cell derived neurotrophic factor (GDNF)
  • Atf-2 protein
  • ATF1 protein
  • ATF2 protein
  • atf2-A protein
  • atf2l protein
  • CG3749 protein
  • CG12850 protein
  • CG30420 protein
  • CHN1 protein
  • CRE-BP protein
  • CRE-BP1 protein
  • Creb2 protein
  • D18875 protein
  • D130078H02Rik protein
  • dATF-2 protein
  • DmelCG30420 protein
  • HB16 protein
  • HFB1-GDNF protein
  • HSCR3 protein
  • mXBP protein
  • Tg(Gzma-Klra1)7Wum protein
  • TREB7 protein

Protein level used designations for ATF2

chimerin (chimaerin) 1 , activating transcription factor-2, isoform A , CG30420-PA , Atf-2-PA , activating transcription factor-2, isoform C , CG30420-PC , Atf-2-PC , activating transcription factor-2, isoform B , CG30420-PB , Atf-2-PB , CREB-2 , activating transcription factor 2 splice variant ATF2-var2 , cAMP response element-binding protein CRE-BP1 , cAMP responsive element binding protein 2, formerly , cAMP-dependent transcription factor ATF-2 , cAMP-responsive element-binding protein 2 , cyclic AMP-dependent transcription factor ATF-2 , cyclic AMP-responsive element-binding protein 2 , cyclic AMP response element binding protein 2 , ATF , astrocyte-derived trophic factor , glial cell line-derived neurotrophic factor

739083 Pan troglodytes
37978 Drosophila melanogaster
1386 Homo sapiens
11909 Mus musculus
81647 Rattus norvegicus
378533 Xenopus laevis
395727 Gallus gallus
478806 Canis lupus familiaris
100053304 Equus caballus
509827 Bos taurus
100513441 Sus scrofa
100726889 Cavia porcellus
100355367 Oryctolagus cuniculus
101108548 Ovis aries
100006516 Danio rerio
2668 Homo sapiens
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