Browse our anti-HSPB1 (HSPB1) Antibodies

Full name:
anti-Heat Shock 27kDa Protein 1 Antibodies (HSPB1)
On are 833 Heat Shock 27kDa Protein 1 (HSPB1) Antibodies from 34 different suppliers available. Additionally we are shipping HSPB1 Kits (59) and HSPB1 Proteins (28) and many more products for this protein. A total of 947 HSPB1 products are currently listed.
27kDa, 2810021G24Rik, cb153, cb660, CMT2F, HMN2B, HS.76067, Hs.78846, hsp1, Hsp25, Hsp27, HSP28, HSPB1, id:ibd2821, LOH11CR1K, MKBP, sb:cb660, SRP27, zgc:103437
list all antibodies Gene Name GeneID UniProt
HSPB1 3315 P04792
Anti-Rat HSPB1 HSPB1 24471 P42930
HSPB1 15507 P14602

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Top referenced anti-HSPB1 Antibodies

  1. Human Polyclonal HSPB1 Primary Antibody for EIA, WB - ABIN453119 : Wano, Kita, Takahashi, Sugaya, Hino, Hosoya, Suzuki: Protective role of HSP27 against UVC-induced cell death in human cells. in Experimental cell research 2004 (PubMed)
    Show all 5 references for 453119

  2. Human Polyclonal HSPB1 Primary Antibody for EIA - ABIN358314 : Evgrafov, Mersiyanova, Irobi, Van Den Bosch, Dierick, Leung, Schagina, Verpoorten, Van Impe, Fedotov, Dadali, Auer-Grumbach, Windpassinger, Wagner, Mitrovic, Hilton-Jones, Talbot, Martin, Vasserman et al.: Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. ... in Nature genetics 2004 (PubMed)
    Show all 5 references for 358314

  3. Human Monoclonal HSPB1 Primary Antibody for EIA, IHC (p) - ABIN317528 : Charette, Lavoie, Lambert, Landry: Inhibition of Daxx-mediated apoptosis by heat shock protein 27. in Molecular and cellular biology 2000 (PubMed)
    Show all 3 references for 317528

  4. Human Polyclonal HSPB1 Primary Antibody for IHC, WB - ABIN2779293 : Lelj-Garolla, Mauk: Self-association and chaperone activity of Hsp27 are thermally activated. in The Journal of biological chemistry 2006 (PubMed)
    Show all 3 references for 2779293

  5. Human Polyclonal HSPB1 Primary Antibody for IHC (p), WB - ABIN391298 : Song, Ethier, Dziubinski, Lin: Stat3 modulates heat shock 27kDa protein expression in breast epithelial cells. in Biochemical and biophysical research communications 2004 (PubMed)
    Show all 2 references for 391298

  6. Human Polyclonal HSPB1 Primary Antibody for IHC (p), WB - ABIN391299 : Chauhan, Li, Hideshima, Podar, Mitsiades, Mitsiades, Catley, Tai, Hayashi, Shringarpure, Burger, Munshi, Ohtake, Saxena, Anderson: Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance. in Blood 2003 (PubMed)
    Show all 2 references for 391299

  7. Human Polyclonal HSPB1 Primary Antibody for IF (p), IHC (p) - ABIN672441 : Wang, Yang, Liu, Zhou, Wu, Qiao, Li, Wang: Dietary supplementation with the probiotic Lactobacillus fermentum I5007 and the antibiotic aureomycin differentially affects the small intestinal proteomes of weanling piglets. in The Journal of nutrition 2011 (PubMed)
    Show all 2 references for 672441

More Antibodies against HSPB1 Interaction Partners

Zebrafish Heat Shock 27kDa Protein 1 (HSPB1) interaction partners

  1. Loss of HspB1 specifically reduces myofibril size in embryonic craniofacial muscles.

  2. Results show the sequence, expression, regulation, and function of a zebrafish protein (zfHsp27) and define zebrafish as a new model for the study of Hsp27 function.

  3. initial upregulation of hsp27 expression occurs during early gastrulation

  4. hspb1 is expressed during development

  5. Hsp27 is dispensable for zebrafish morphogenesis but could play a role in long-term maintenance of heart and muscle tissues.

  6. The data support a mechanism of Hsp27 function where interactions with the titin (show TTN Antibodies) filament system protect myofibrils from stress-induced degradation.

Xenopus laevis Heat Shock 27kDa Protein 1 (HSPB1) interaction partners

  1. Xenopus HSP27, like HSP30, is a developmentally-regulated heat-inducible molecular chaperone (show HSP90AA1 Antibodies).

Human Heat Shock 27kDa Protein 1 (HSPB1) interaction partners

  1. Data suggest that hnRNPK plays role in heat shock response of cells by regulating HSF1; hnRNPK inhibits HSF1 activity, resulting in reduced expression of HSP27 and HSP70 mRNAs; hnRNPK also down-regulates binding of HSF1 to heat shock response element. (hnRNPK = heterogeneous-nuclear ribonucleoprotein K; HSF1 = heat shock transcription factor 1; HSP = heat-shock protein)

  2. High Hsp27 expression is associated with Thyroid Tumors.

  3. There is overwhelming evidence that molecular chaperones such as Hsp27, Hsp70 (show HSP70 Antibodies) and Hsp90 (show HSP90 Antibodies) are expressed at elevated levels in a wide range of cancers by stabilizing the mutated neoplasm proteins. (Review)

  4. Bradykinin stimulates myofibroblast migration through protein kinase D (show PRKD1 Antibodies)-mediated activation of COX-2 (show COX2 Antibodies) and Hsp27.

  5. Data suggest that HSPB6 forms hetero-oligomers with HSPB1 under the following rules: (1) highly conserved motif RLFDQXFG is necessary for subunit exchange among oligomers, (2) a site about 20 residues downstream of this motif determines size of resultant hetero-oligomers, and (3) a region in the N-terminal domain that is unique to HSPB6 dictates preferential formation of heterodimers. (HSP = heat shock protein)

  6. TNF-alpha (show TNF Antibodies) stimulates colonic myofibroblast migration through P38 MAPK (show MAPK14 Antibodies)-mediated activation of COX-2 (show COX2 Antibodies) and Hsp27.

  7. The potency of the sHsps to suppress aggregation of model substrates is correlated with their ability to form stable substrate complexes; especially HspB1 and HspB5 (show CRYAB Antibodies), but also B3, bind tightly to a variety of proteins

  8. This work examines the molecular mechanism by which two canonical sHsps, alphaB-crystallin (show CRYAB Antibodies) (alphaB-c) and Hsp27, interact with aggregation-prone alpha-syn to prevent its aggregation in vitro Both sHsps are very effective inhibitors of alpha-syn aggregation

  9. This study highlights a novel relation between serum pHSP27 and BMD (show BEST1 Antibodies) in Indian women however, these findings need to be confirmed in larger studies

  10. High HSP27 expression is associated with chemoresistance in neoplasms.

Cow (Bovine) Heat Shock 27kDa Protein 1 (HSPB1) interaction partners

  1. These findings suggest that HSPB1 mediates androgen signaling by binding directly to androgen receptor (show AR Antibodies) and then enhancing androgen-mediated myogenesis in myogenic cells.

  2. HSPB1 could have an important role during testosterone-related myogenesis.

  3. CaMKII (show CAMK2G Antibodies) is required for redox-sensitive activation of p38 MAPK (show MAPK14 Antibodies)/heat shock protein 27 pathway and ERK1/2 (show MAPK1/3 Antibodies)

Pig (Porcine) Heat Shock 27kDa Protein 1 (HSPB1) interaction partners

  1. It indicated that Hsp27 was required for porcine circovirus type 2 replication in PK-15 cells culture.

  2. HSP27 expression is gut (show GUSB Antibodies) region- and cell type-specific in response to dietary components, microbes, and microbial metabolites to which the mucosa surface is exposed.

  3. These results indicate that Hsp27 expression in the porcine gut (show GUSB Antibodies) could be associated with specific dietary fiber components but not the overall microbiota diversity.

  4. Data suggest that targeting HSP27 might offer a useful strategy in cancer treatment.

  5. Data show that the expression of HSP27 and CLIC1 (show CLIC1 Antibodies) was strongly positive in 61 (59.2%) and 49 cases (47.6%), respectively.

  6. Data suggest that HSP27 enhanced the metastatic property of NPC (show NPC1 Antibodies) cells probably via the NF-kappaB (show NFKB1 Antibodies)-mediated activation of MMPs.

  7. Hsp27 expression and its direct chaperoning interaction increase Akt (show AKT1 Antibodies) stability and p21 (show CDKN1A Antibodies) phosphorylation and nuclear-to-cytoplasm translocation, both essential effects for the survival of ultraviolet-induced DNA-damaged cells.

  8. HSP27 could be a good candidate involved in migration and/or function of neutrophils within the porcine endmetrium.

  9. HSP27 and HSP70 (show HSP70 Antibodies) may be used as differential markers to distinguish conventional and low grade central osteosarcoma.

  10. HSP-27 and HSP-70 (show HSP70 Antibodies) contribute to modulation of K(+) channel (show KCNC4 Antibodies)-induced pial artery dilation

Mouse (Murine) Heat Shock 27kDa Protein 1 (HSPB1) interaction partners

  1. AMPK (show PRKAA1 Antibodies)-mediated HSPB1 expression enhanced insulin (show INS Antibodies) sensitivity in the skeletal muscle.

  2. e confirmed the modulatory effect of Hspb1 on Purkinje cell degeneration (show AGTPBP1 Antibodies) in vivo, as knockdown by Hspb1 shRNA significantly enhanced neuron loss. These results suggest that strategies to promote HSPB1 activity may slow the rate of cerebellar degeneration in NPC (show NPC1 Antibodies) disease and highlight the use of bioinformatics tools to uncover pathways leading to neuronal protection in neurodegenerative disorders

  3. Dp71Delta78-79 dystrophin (show DMD Antibodies) mutant stimulates neurite outgrowth in cultured neuronal cells via upregulation and phosphorylation of HspB1.

  4. HSP27 expression is upregulated in lung fibroblasts during pulmonary fibrosis, and subsequently, HSP27 modulates lung fibroblast differentiation through the Smad3 (show SMAD3 Antibodies) and ERK (show EPHB2 Antibodies) pathways.

  5. phosphorylated Hsp27 stimulates autophagy and lipid droplet clearance and interacts with STAT3 (show STAT3 Antibodies).

  6. The phosphorylation of S82 of the heat shock protein 27 kDa (HSP27), was especially abundant and consistently upregulated in tissues with delays in freezing as short as 2 minutes.

  7. HSPB1 depletion in a mouse model of lung tumorigenesis induced the endothelial-to-mesenchymal transition

  8. HspB2 (show HSPB2 Antibodies) has roles in maintaining ATP levels and as well as chaperone-dependent functions for metabolic homeostasis

  9. Overexpression of HSP27-S135F protein causes peripheral neuropathy. The mouse model can be applied to future development of therapeutic strategies forhereditary motor neuropathy (dHMN) and Charcot-Marie-Tooth disease type 2 F.

  10. cardiac HMGB1 (show HMGB1 Antibodies) increases HSPB1 expression and attenuates cardiomyocyte apoptosis associated with doxorubicin-induced cardiomyopathy.

HSPB1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function.

Alternative names and synonyms associated with HSPB1

  • heat shock protein, alpha-crystallin-related, 1 (hspb1) antibody
  • heat shock 27kDa protein 1 (hspb1) antibody
  • heat shock 27kDa protein 1 (HSPB1) antibody
  • heat shock 27kDa protein 1 (HSP27) antibody
  • heat shock 27kDa protein 2 (HSPB2) antibody
  • heat shock protein 1 (Hspb1) antibody
  • heat shock protein 2 (Hspb2) antibody
  • heat shock protein 25 (HSP25) antibody
  • 27kDa antibody
  • 2810021G24Rik antibody
  • cb153 antibody
  • cb660 antibody
  • CMT2F antibody
  • HMN2B antibody
  • HS.76067 antibody
  • Hs.78846 antibody
  • hsp1 antibody
  • Hsp25 antibody
  • Hsp27 antibody
  • HSP28 antibody
  • HSPB1 antibody
  • id:ibd2821 antibody
  • LOH11CR1K antibody
  • MKBP antibody
  • sb:cb660 antibody
  • SRP27 antibody
  • zgc:103437 antibody

Protein level used designations for HSPB1

25 kDa heat shock protein , heat shock 27kDa protein 1 , heat shock protein 27 , heat shock protein beta-1 , 28 kDa heat shock protein , HSP 27 , estrogen-regulated 24 kDa protein , heat shock 27 kDa protein , heat shock 27kD protein 1 , stress-responsive protein 27 , heat-shock protein , 25 kDa IAP , HSP 25 , actin polymerization inhibitor , heat shock 25 kDa protein , inhibitor of actin polymerization , DMPK-binding protein , heat shock protein beta-2 , heat-shock protein beta-2 , heat shock 27 kDa protein 1 , growth-related 25 kDa protein , heat shock protein, 25 kDa , p25 , truncated hsp25 , heat shock 27kD protein 2

368243 Danio rerio
447107 Xenopus laevis
463488 Pan troglodytes
715615 Macaca mulatta
780278 Xenopus (Silurana) tropicalis
3315 Homo sapiens
403979 Canis lupus familiaris
396227 Gallus gallus
516099 Bos taurus
493184 Sus scrofa
3316 Homo sapiens
24471 Rattus norvegicus
15507 Mus musculus
69253 Mus musculus
428310 Gallus gallus
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