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MKNK2 Proteins

(MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2))
This gene encodes a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex. Multiple alternatively spliced transcript variants have been found, but the full-length nature and biological activity of only two variants are determined. These two variants encode distinct isoforms which differ in activity and regulation, and in subcellular localization. [provided by RefSeq, Aug 2011].
MKNK2 Protein (AA 1-465) (His tag) MKNK2 Protein (AA 1-465) (His tag) MKNK2 Protein (AA 1-465) (His tag) (ABIN3093826)

Crystallography grade MKNK2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys

MKNK2 Protein (Thr379Asp-Mutant) (GST tag) MKNK2 Protein (Thr379Asp-Mutant) (GST tag) MKNK2 Protein (Thr379Asp-Mutant) (GST tag) (ABIN5570743)

MKNK2 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active

MKNK2 Protein (AA 41-158) (GST tag) MKNK2 Protein (AA 41-158) (GST tag) MKNK2 Protein (AA 41-158) (GST tag) (ABIN1310980)

MKNK2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

MKNK2 Proteins by Grade

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MKNK2 Proteins by Origin

Find MKNK2 Proteins for a variety of species such as anti-Human MKNK2, anti-Mouse MKNK2, anti-Rat MKNK2. The species listed below are among those available. Click on a link to go to the corresponding products.

MKNK2 Proteins by Source

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MKNK2 Proteins by Protein Type

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MKNK2 Proteins by Application

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MKNK2 Proteins by Biological Activity

Find MKNK2 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular MKNK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (3)
Cat. No. ABIN3093826
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570743
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310980
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310978
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136414
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509021
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN2726085
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2726084
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1635067
Quantity 1 mg
Datasheet Datasheet
Reactivity Xenopus laevis
Source Yeast
Validations
Cat. No. ABIN1674333
Quantity 1 mg
Datasheet Datasheet

Aliases for MKNK2 Proteins

MAP kinase interacting serine/threonine kinase 2 (MKNK2) Proteins
MAP kinase interacting serine/threonine kinase 2 (mknk2) Proteins
MAP kinase-interacting serine/threonine kinase 2 (Mknk2) Proteins
MAP kinase interacting serine/threonine kinase 2b (mknk2b) Proteins
MAP kinase interacting serine/threonine kinase 2 L homeolog (mknk2.L) Proteins
MAP kinase interacting serine/threonine kinase 2 (Mknk2) Proteins
MAP kinase interacting serine/threonine kinase 2a (mknk2a) Proteins
2010016G11Rik Proteins
fi34c11 Proteins
GPRK7 Proteins
gprk7 Proteins
Gprk7 Proteins
mknk2 Proteins
MNK2 Proteins
mnk2 Proteins
Mnk2 Proteins
wu:fb37e05 Proteins
wu:fi34c11 Proteins
wu:fi41e12 Proteins
wz5090 Proteins
zgc:55587 Proteins
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