Browse our Paxillin Proteins (PXN)

On are 17 Paxillin (PXN) Proteins from 7 different suppliers available. Additionally we are shipping Paxillin Antibodies (404) and Paxillin Kits (39) and many more products for this protein. A total of 484 Paxillin products are currently listed.
AW108311, AW123232, CG18061, CG18576, CG31794, CT40481, CT42454, Dmel\\CG31794, dPax, DpaxA, DPaxillin, DPxn, DPxn37, LOC100220858, Pax, PDLP, PXN, wu:fw71f12
list all proteins Gene Name GeneID UniProt
PXN 5829 P49023
PXN 19303 Q8VI36
PXN 360820 Q66H76

Paxillin Proteins (PXN) by Origin

More Proteins for Paxillin Interaction Partners

Fruit Fly (Drosophila melanogaster) Paxillin (PXN) interaction partners

  1. Data indicate that tramtrack69 regulates ovary epithelial tube morphogenesis through Paxillin, Dynamin (show DNM1 Proteins), and the homeobox protein (show HOXA1 Proteins) Mirror.

  2. New insights from hemichordate genomes: prebilaterian origin and parallel modifications in the paired domain of the Pax gene eyegone

  3. Results identify a link between the focal adhesion protein paxillin and the Atg1 (show ULK1 Proteins) kinase, which has been previously implicated in autophagy.

  4. Data show that Pax genes are involved in the development of the anterior/posterior brain boundary zone during embryonic CNS development in Drosophila.

Human Paxillin (PXN) interaction partners

  1. Recruitment of Paxillin, Cdc42 (show CDC42 Proteins) and N-WASP (show WASL Proteins) is necessary for cell adhesion, migration and invasion induced by Estradiol in breast cancer cells.

  2. the administration of 10(-6) M retinoic acid (10-20 min) induces the activation of the migration-related proteins Moesin (show MSN Proteins), FAK (show PTK2 Proteins), and Paxillin in T-47D breast cancer cells.

  3. The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing paxillin expression through the alternative splicing of lncRNA-PXN-AS1.

  4. These data suggest that paxillin appears to influence major cell functions in a diverse range of prostate and breast cancer models. The responsiveness of cells to environmental factors such as HGF (show HGF Proteins) or BME may be influenced by paxillin status, although this seems to be dependent on cell type

  5. Knocking out FAK (show PTK2 Proteins) (also known as PTK2 (show PTK2 Proteins)) and vinculin (show VCL Proteins) caused an increase in nuclear paxillin. This could be reversed by rescue with wild-type FAK (show PTK2 Proteins) but not by FAK (show PTK2 Proteins) with a mutated FAT domain, which inhibits paxillin binding.

  6. The role of paxillin in the aging process of skin cells is reviewed.

  7. interactions between Cat-1 (show CRAT Proteins) and its binding partner paxillin are necessary to ensure sufficient Akt (show AKT1 Proteins) activation so that cancer cells are able to grow under anchorage-independent conditions

  8. FAK (show PTK2 Proteins)/SRC (show SRC Proteins) and paxillin play a role in the pathophysiological aspects of mobile tongue squamous cell carcinoma and could constitute therapeutic targets

  9. The present findings demonstrated that the anticancer effect of docetaxel induces the apoptosis of prostate cancer via the suppression of the cofilin1 and paxillin signaling pathways, which will assist in setting a stage for the clinical treatment of prostate cancer.

  10. Results showed that the positive rate of PXN was significantly higher in the colorectal adenocarcinoma samples and correlated with TNM (show ODZ1 Proteins) stage, distant metastasis and recurrence additionally to cetuximab resistance.

Mouse (Murine) Paxillin (PXN) interaction partners

  1. Data show that actomyosin cytoskeletal contractility is required for paxillin localization to developing somite boundaries.

  2. paxillin and Hic-5 (show TGFB1I1 Proteins) have both redundant and distinctive functions in invadosome formation.

  3. Fyn (show FYN Proteins) mediates high glucose-induced actin cytoskeleton remodeling of podocytes via promoting ROCK activation and paxillin phosphorylation

  4. Lithium therapy abrogated GSK3beta overactivity, blunted paxillin hyperphosphorylation, and reinstated actin cytoskeleton integrity in glomeruli associated with an early attenuation of podocyte foot process effacement.

  5. Suggest paxillin up-regulation and phosphorylation as an important mechanism of vascular remodelling underlying pulmonary hypertension.

  6. LPS-induced paxillin phosphorylation at Y31 and Y118 was mediated by c-Abl tyrosine kinase

  7. Study provides evidence that phosphorylation of PXN is required for cisplatin resistance in lung cancer cells.

  8. MELK (show MELK Proteins) promotes cell migration and invasion via the FAK (show PTK2 Proteins)/Paxillin pathway, and plays an important role in the occurrence and development of gastric cancer.

  9. FAK (show PTK2 Proteins)-paxillin interactions are indispensable for cell adhesion, migration and invasion processes.

  10. paxillin and zyxin (show ZYX Proteins) are LIM (show PDLIM5 Proteins)-domain adaptor proteins that are recruited to stress fiber strain sites

Zebrafish Paxillin (PXN) interaction partners

  1. paxillin may function in adhesion during the morphogenesis of the early zebrafish embryo

Xenopus laevis Paxillin (PXN) interaction partners

  1. Paxillin has a role in meiosis and may be a general modulator of mitogen-activated protein kinase (show MAPK1 Proteins) signaling

  2. RING finger protein (show TRIM31 Proteins) XRNF185 (show RNF185 Proteins), which physically binds to paxillin and the proteasome. XRNF185 (show RNF185 Proteins) destabilizes paxillin at focal adhesions and promotes mesodermal cell migration during convergent extension.

Pig (Porcine) Paxillin (PXN) interaction partners

  1. Role of Y118 paxillin phosphorylation and stimulated actin polymerization in carotid artery contraction.

Paxillin (PXN) Protein Profile

Protein Summary

This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).

Alternative names and synonyms associated with Paxillin (PXN)

  • paxillin (PXN)
  • Paxillin (Pax)
  • paxillin (pxn)
  • paxillin (LOC100220858)
  • paxillin (Pxn)
  • paxillin-like (LOC100353305)
  • AW108311 protein
  • AW123232 protein
  • CG18061 protein
  • CG18576 protein
  • CG31794 protein
  • CT40481 protein
  • CT42454 protein
  • Dmel\\CG31794 protein
  • dPax protein
  • DpaxA protein
  • DPaxillin protein
  • DPxn protein
  • DPxn37 protein
  • LOC100220858 protein
  • Pax protein
  • PDLP protein
  • PXN protein
  • wu:fw71f12 protein

Protein level used designations for Paxillin Proteins (PXN)

CG31794-PA , CG31794-PB , CG31794-PC , CG31794-PD , CG31794-PF , CG31794-PG , CG31794-PH , CG31794-PJ , CG31794-PK , D-Paxillin , Pax-PA , Pax-PB , Pax-PC , Pax-PD , Pax-PF , Pax-PG , Pax-PH , Pax-PJ , Pax-PK , Paxillin-derived LIM-only protein , paxillin , myocardial ischemic preconditioning associated protein 7

100053811 Equus caballus
35215 Drosophila melanogaster
452303 Pan troglodytes
696336 Macaca mulatta
100216044 Xenopus (Silurana) tropicalis
100220858 Taeniopygia guttata
100474505 Ailuropoda melanoleuca
5829 Homo sapiens
19303 Mus musculus
360820 Rattus norvegicus
395832 Gallus gallus
517456 Bos taurus
399546 Danio rerio
397826 Xenopus laevis
486299 Canis lupus familiaris
100732427 Cavia porcellus
100126846 Sus scrofa
100173313 Pongo abelii
100353305 Oryctolagus cuniculus
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