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Browse our PPARG Proteins (PPARG)

Full name:
Peroxisome Proliferator-Activated Receptor gamma Proteins (PPARG)
On are 48 Peroxisome Proliferator-Activated Receptor gamma (PPARG) Proteins from 15 different suppliers available. Additionally we are shipping PPARG Antibodies (308) and PPARG Kits (86) and many more products for this protein. A total of 459 PPARG products are currently listed.
list all proteins Gene Name GeneID UniProt
PPARG 19016 P37238
PPARG 5468 P37231
PPARG 25664 O88275

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PPARG Proteins (PPARG) by Origin

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Top referenced PPARG Proteins

  1. Human PPARG Primary Antibody for SDS - ABIN667157 : Berger, Moller: The mechanisms of action of PPARs. in Annual review of medicine 2002 (PubMed)
    Show all 2 references for ABIN667157

More Proteins for PPARG Interaction Partners

Mouse (Murine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. study demonstrates that tamoxifen inhibits CD36 (show CD36 Proteins) expression and cellular oxLDL accumulation by inactivating the PPARgamma signaling pathway, and the inhibition of macrophage CD36 (show CD36 Proteins) expression can be attributed to the anti-atherogenic properties of tamoxifen.

  2. PPARbeta (show PPARD Proteins)/PPARgamma activation restored the LPS (show TLR4 Proteins)-induced endothelial dysfunction by upregulation of UCP2 (show UCP2 Proteins), with the subsequent alleviation of ER stress and NADPH oxidase (show NOX1 Proteins) activity, thus reducing intracellular reactive oxygen species production and increasing nitric oxide bioavailability.

  3. betaine ameliorates hepatic steatosis, at least in part, by inhibiting the FoxO1 (show FOXO1 Proteins) binding to PPARgamma and their downstream lipogenic signaling cascade

  4. The results of the present study indicate that atorvastatin exhibits significant antiinflammatory effects in OGD (show FGFR1 Proteins)/reperfusionstimulated RAW264.7 cells, possibly via PPARgamma regulation. The findings of the present study may reveal a novel mechanism underlying the protective effects of atorvastatin in I/R injuryassociated diseases.

  5. this study shows that down-regulation of PPARgamma may be involved in neuroinflammation and subsequent postoperative cognitive decline in aged mice

  6. this study shows that Irbesartan can ameliorate hyperlipidemia and liver steatosis by upregulating the expression of PPARg

  7. Progesterone can play dual pathophysiological roles by activating PPARgamma expression, in which progesterone increases macrophage CD36 (show CD36 Proteins) expression and oxLDL accumulation, a negative effect on atherosclerosis, and enhances the PPARgamma-CD36 (show CD36 Proteins) pathway in adipose tissue and skeletal muscle, a protective effect on pregnancy.

  8. There was a possible regulatory link between Twist 1 (show TWIST1 Proteins) and PPARgamma in 3T3-L1 mature adipocytes. This regulatory link enhanced the regulation of PPARgamma and may be a functional mechanism of Twist 1 (show TWIST1 Proteins) regulation of adipocyte physiology and pathology

  9. Fenretinide might be a potent antihypertensive agent that works by suppressing inflammation via activating PPARgamma.

  10. Data suggest that the production of 15d-PGJ2, which is mediated by cyclooxygenase 2 (COX-2 (show PTGS2 Proteins)), induces non-alcoholic fatty liver disease (NAFLD) and hepatic insulin (show INS Proteins) resistance by activating peroxisome proliferator-activated receptor gamma (PPARgamma) .

Human Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. study demonstrates that tamoxifen inhibits CD36 (show CD36 Proteins) expression and cellular oxLDL accumulation by inactivating the PPARgamma signaling pathway, and the inhibition of macrophage CD36 (show CD36 Proteins) expression can be attributed to the anti-atherogenic properties of tamoxifen.

  2. Hypoxia causes transient activation of human pulmonary artery smooth muscle cell HIF-1alpha (show HIF1A Proteins) that is attenuated by rosiglitazone treatment initiated at hypoxia onset. These findings provide novel evidence that PPARgamma modulates fundamental and acute cellular responses to hypoxia through both HIF-1 (show HIF1A Proteins)-dependent and HIF-1 (show HIF1A Proteins)-independent mechanisms.

  3. these data indicate AR serves as a key modulator of PPARgamma expression and function within prostate tumors.

  4. To evaluate the influence of diets rich in polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) on anthropometric and biochemical variables in obese woman with genotype Pro12Pro on PPARgamma2 gene on body weight, glycemic and lipemic profile

  5. the regulation of PPARgamma transcriptional activity associated with natural products through the antagonism of PPARgamma and activation of Sirtuin 1 (Sirt1 (show SIRT1 Proteins)) and AMP-activated protein kinase (AMPK (show PRKAA2 Proteins)) were discussed.

  6. miR128 inhibition attenuated I/R injuryinduced cardiomyocyte apoptosis by the targeted activation of PPARG signaling.

  7. PPARg signaling pathway may involve in the proliferation inhibition of evodiamine on K562 cells via inhibiting cylcin D1 and stimulating of p21 (show CDKN1A Proteins).

  8. Low PPARgamma expression is associated with macroscopic Vascular Invasion in Hepatocellular Carcinoma.

  9. PPARalpha (show PPARA Proteins)/gamma agonist, elafibranor resolves nonalcoholic steatohepatitis without worsening fibrosis.

  10. Findings of this study suggest that CYP46A1 (show CYP46A1 Proteins) gene and PPARgamma2 gene polymorphisms can be a predictive marker for early identification of population at risk of primary open angle glaucoma (POAG).

Pig (Porcine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. The data suggest that there is local cooperation between resistin (show RETN Proteins) and PPARgamma expression in the porcine ovary. Resistin (show RETN Proteins) significantly increased the expression of PPARgamma, whereas PPARgamma decreased resistin (show RETN Proteins) expression; thus, PPARgamma is a new key regulator of resistin (show RETN Proteins) expression and function.

  2. Therefore, this study demonstrated that the different regulatory adipogenic roles of MSTN (show MSTN Proteins) in ADSCs and MSCs act by differentially regulating PPARgamma and MyoD (show MYOD1 Proteins) expression.

  3. PGRN (show GRN Proteins) inhibits adipogenesis in porcine preadipocytes partially through ERK (show MAPK1 Proteins) activation mediated PPARgamma phosphorylation.

  4. Resveratrol activated sirtuin 1 (Sirt1 (show SIRT1 Proteins)) gene expression and increased adipose triglyceride lipase (ATGL (show PNPLA2 Proteins)) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 (show SIRT1 Proteins) regulation pattern for PPARgamma to that of ATGL (show PNPLA2 Proteins) in adipocytes.

  5. The results indicate that the endometrial expression of PPARgamma genes fluctuates during the estrous cycle and pregnancy.

  6. Increasing dietary DE linearly enhanced the expression of PPARgamma in adipose tissues but not skeletal muscle of Rongchang piglets.

  7. These results suggest that trans-10, cis (show CISH Proteins)-12-conjugated linoleic acid can modulate TNF-alpha (show TNF Proteins) production and NF-kappa B (show NFKB1 Proteins) expression by a PPARgamma-dependent pathway in porcine peripheral blood mononuclear cells.

  8. The results indicated that PPARgamma gene was significantly associated with litter size in pigs.

  9. Results indicated that PPARgamma is an essential regulatory factor for the transcriptional activity of ERp44 (show ERP44 Proteins), which in turn controls the secretion of adiponectin (show ADIPOQ Proteins).

  10. Endothelium on the pathosusceptible side of the aortic valve leaflet is responds to hypercholesterolemia with activation of a PPAR-gamma pathway.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. PPARgamma is a positive regulator of milk fat synthesis in dairy cow mammary epithelial cells.

  2. An Asp7Gly substitution in PPARG is associated with adiposity.

  3. upregulation of PPARgamma was observed in the backfat tissue of Lilu cattle with increasing age

  4. Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta (show CEBPB Proteins) and PPAR-gamma gene expression in differentiated myoblasts and an increase in GPR43 (show FFAR2 Proteins) gene expression in adipocytes.

  5. A potential association of an single nucleotide polymorphism (72472 GT in exon7) of the bovine PPAR-gamma gene with carcass and meat quality traits, was evaluated.

  6. study demonstrates the co-expression of DLX3 (show DLX3 Proteins), PPARG and SP1 (show SP1 Proteins) in trophoblast binucleated cell(BNC)nuclei; this suggests a possible role of these transcription factors through BNC specific genes at the time of pre-placental differentiation

  7. Single nucleotide polymorphisms in coding region of the PPARgamma gene, were examined.

  8. oxidative stress attenuates PPAR gamma expression and activity in vascular endothelial cells

  9. The effects of dietary fat components on the expression of PPAR-gamma AND PPAR-gamma coactivator 1 in cultured bovine preadipocytes are reported.

  10. Intramammary infection elicited a strong transcriptomic response, leading to potent activation of pro-inflammatory pathways that were associated with a marked inhibition of lipid synthesis, stress-activated kinase signaling cascades, and PPAR (show PPARA Proteins) signaling.

Rhesus Monkey Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. study found PPAR-gamma expression was prominent in the subthalamic nucleus, oculomotor nucleus, ventral tegmental nucleus, and to a lesser extent, in the putamen; 3 or 12 months after MPTP (show PTPN2 Proteins), only the lesioned putamen had increased PPAR-gamma

  2. Aleglitazar, a dual PPARalpha (show PPARA Proteins)/gamma agonist, has beneficial effects on both lipid and glucose parameters in a primate model of the metabolic syndrome.

Rabbit Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. siRNA targeting PPARgamma gene can inhibit adipogenic differentiation of BMSCs and prevent steroid-induced osteonecrosis in rabbit.

  2. vitamin E supplementation affords protection by decreasing MMP-1 (show MMP1 Proteins) and increasing PPARg, GSTa (show GSTa2 Proteins), and ABCA1 (show ABCA1 Proteins) levels in aortae of rabbits fed a cholesterol-rich diet

  3. Telmisartan improves microvascular dysfunction during myocardial ischemia/reperfusion injury via the PPARgamma pathway.

  4. PPARgamma plays a luteotropic role in pseudopregnant rabbits, through PTGS2 (show PTGS2 Proteins) down-regulation and 3beta-HSD (show HAL Proteins) up-regulation, with a consequent PGF2alpha decrease and progesterone increase.

  5. In an animal model of atherosclerosis, the expression of PPAR-gamma is upregulated following atorvastatin administration.

  6. Tongxinluo can inhibit the expression of MMP-3 (show MMP3 Proteins) and 9 and increase the expression of PPARgamma in atherosclerotic rabbits.

  7. Niacin Reduces serum level and adipose mRNA expression of leptin (show LEP Proteins) and up-regulates PPARgamma and CD36 (show CD36 Proteins) mRNA expression in hypercholesterolemic rabbits.

  8. Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase (show PIK3CA Proteins), Akt (show AKT1 Proteins), and eNOS (show NOS3 Proteins) pathway in a rabbit model of myocardial infarction.

PPARG Protein Profile

Protein Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Alternative names and synonyms associated with PPARG

  • peroxisome proliferator-activated receptor gamma (PPARG)
  • peroxisome proliferator activated receptor gamma (Pparg)
  • peroxisome proliferator-activated receptor gamma (Pparg)
  • peroxisome proliferator-activated receptor gamma (pparg)
  • PPAR gamma 3 (LOC100008892)
  • CIMT1 protein
  • GLM1 protein
  • NR1C3 protein
  • PPAR-GAMMA protein
  • PPAR-gamma2 protein
  • PPARG protein
  • PPARG1 protein
  • PPARG2 protein
  • PPAR gamma protein
  • PPARGAMMA protein
  • PPARgamma2 protein
  • xPPAR-gamma protein

Protein level used designations for PPARG

peroxisome proliferator activated receptor gamma , peroxisome proliferative activated receptor gamma , peroxisome proliferator-activated receptor gamma , peroxisome proliferator activator receptor gamma , nuclear receptor subfamily 1 group C member 3 , peroxisome proliferator activated receptor gamma 2 , peroxisome proliferator activated receptor gamma 4 , Nuclear receptor subfamily 1 group C member 3 , PPAR gamma , PPAR-gamma , peroxisome proliferator-activated nuclear receptor gamma variant 1 , peroxisome proliferator-activated receptor gamma 1 , peroxisome proliferator activator receptor, gamma , PPAR gamma 2 , xPPAR gamma , peroxisome proliferative activated receptor, gamma , peroxisome proliferator-activated receptor gamma 2 , peroxisome proliferator-activated receptor gamma 1-a , peroxisome proliferator-activated receptor gamma 1-b , PPAR gamma 1 , peroxisome proliferator activated receptor gamma-1 , peroxisome proliferator-activated receptor-gamma

443513 Ovis aries
460178 Pan troglodytes
100049014 Felis catus
100581046 Nomascus leucogenys
19016 Mus musculus
100689245 Cricetulus griseus
5468 Homo sapiens
25664 Rattus norvegicus
397769 Xenopus laevis
373928 Gallus gallus
403606 Canis lupus familiaris
397671 Sus scrofa
281993 Bos taurus
100729138 Cavia porcellus
574190 Macaca mulatta
100008892 Oryctolagus cuniculus
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