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Browse our PPARG Proteins (PPARG)

Full name:
Peroxisome Proliferator-Activated Receptor gamma Proteins (PPARG)
On are 43 Peroxisome Proliferator-Activated Receptor gamma (PPARG) Proteins from 15 different suppliers available. Additionally we are shipping PPARG Antibodies (292) and PPARG Kits (79) and many more products for this protein. A total of 431 PPARG products are currently listed.
list all proteins Gene Name GeneID UniProt
PPARG 19016 P37238
PPARG 5468 P37231
PPARG 25664 O88275

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PPARG Proteins (PPARG) by Origin

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Top referenced PPARG Proteins

  1. Human PPARG Protein expressed in Escherichia coli (E. coli) - ABIN667157 : Berger, Moller: The mechanisms of action of PPARs. in Annual review of medicine 2002 (PubMed)
    Show all 2 references for ABIN667157

More Proteins for PPARG Interaction Partners

Mouse (Murine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. PPAR-gamma over-expression perturbs the intracellular calcium homeostasis in cardiomyocytes which contribute to the ventricular arrhythmias and cardiac sudden death in transgenic -PPAR-gamma mice.

  2. P. aculeata is effective to improve insulin (show INS Proteins) resistance in a mouse model of obesity and this effect seems to involve the antioxidant and anti-inflammatory mechanisms through the increase in PPARgamma/CuZn-SOD (show SOD1 Proteins) axis expression.

  3. LPS (show TLR4 Proteins)-induced inflammation is potently compromised by emodin very likely through the PPARgamma-dependent inactivation of NF-kappaB (show NFKB1 Proteins)

  4. Treatment of an Alzheimer's disease mouse model with genistein results in a remarkable and rapid improvement in various parameters of cognition; a lowering of Abeta (show APP Proteins) levels in brain, in the number and the area of amyloid plaques (confirmed in vivo by positron emission tomography) as well as in microglial reactivity; and incubation of primary astrocytes with genistein results in a PPARgamma-mediated increased release of ...

  5. PPARgamma interacted with Mark4 (show MARK4 Proteins) and inhibited the stimulating effect of Mark4 (show MARK4 Proteins) on oxidative stress and inflammation.

  6. PPARgamma plays an important role in sustaining angiogenic potential in mature pulmonary microvascular endothelial cells through E2F1 (show E2F1 Proteins)-mediated gene regulation.

  7. Rosiglitazone modulated the inflammatory response and increased bacterial clearance through PPARgamma activation and NET formation, combining immunomodulatory and host-dependent anti-bacterial effects and, therefore, warrants further study as a potential therapeutic agent in sepsis.

  8. PPARgamma plays a critical role in neutral lipid metabolic signaling controlled by lysosomal acid lipase (show LIPA Proteins), which provides a mechanistic basis for clinically targeting myeloid-derived suppressor cells to reduce the risk of cancer proliferation, growth and metastasis.

  9. interference with endothelial PPARgamma accelerates ANG II (show AGT Proteins)-mediated endothelial dysfunction both in cerebral and conduit arteries through an oxidative stress-dependent mechanism

  10. these results demonstrated that L-carnitine ameliorated liver inflammation and serum pro-inflammatory markers in cancer cachexia through regulating CPT I (show CPT1A Proteins)-dependent PPARg signaling

Human Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. OA treatment represses SIRT1 (show SIRT1 Proteins) and peroxisome proliferator-activated receptors-gamma levels in SMCs.

  2. Data suggest that PPARG (peroxisome proliferator-activated receptor gamma) protects against insecticide-induced cytotoxicity/apoptosis by regulating PINK1 (PTEN induced putative kinase 1 (show PINK1 Proteins)) expression in neurons, including dopaminergic neurons; the insecticide used in these experiments was deltamethrin; the neuroprotective agent was the hypoglycemic agent, rosiglitazone.

  3. PPARgamma is down-regulated in the cisplatin-resistant gastrointestinal cancer cells.

  4. This study found that PPARG C161T was associated with large-artery atherosclerosis ischemic stroke and lower levels of blood total cholesterol and low-density lipoprotein cholesterol.

  5. the current study demonstrated that zinc supplementation for 6 weeks among Gestational Diabetes Mellitus women increased the mRNA levels of PPAR-gamma and GLUT1 (show SLC2A1 Proteins) in their newborns compared with the placebo group.

  6. Suppression of PPARgamma in highly malignant prostate cancer cells produced a significant reduction (up to 53%) in their proliferation rate, invasiveness (up to 89%) and anchorage-independent growth (up to 94%) in vitro.

  7. The results of this meta-analysis suggest that the PPARgamma2 Pro12Ala (rs1801282) polymorphism might be correlated with a higher risk of CVD, particularly MI, and could serve as an important early indicator for CVD.

  8. PPAR-gamma concentrations and their relationship to body mass index, ratio of waist and hip, blood pressure levels, insulin (show INS Proteins) resistance and lipid profile in obese children and adolescents.

  9. EGFR inhibitors induced TNF-alpha via PPARgamma/NFkappaB signaling pathway resulting in papulopustular rash.

  10. The nuclear receptor peroxisome proliferator-activated receptor gamma is the key decisive factor controlling the development of adipocytes. [review]

Pig (Porcine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. Therefore, this study demonstrated that the different regulatory adipogenic roles of MSTN (show MSTN Proteins) in ADSCs and MSCs act by differentially regulating PPARgamma and MyoD (show MYOD1 Proteins) expression.

  2. PGRN (show GRN Proteins) inhibits adipogenesis in porcine preadipocytes partially through ERK (show MAPK1 Proteins) activation mediated PPARgamma phosphorylation.

  3. Resveratrol activated sirtuin 1 (Sirt1 (show SIRT1 Proteins)) gene expression and increased adipose triglyceride lipase (ATGL (show PNPLA2 Proteins)) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 (show SIRT1 Proteins) regulation pattern for PPARgamma to that of ATGL (show PNPLA2 Proteins) in adipocytes.

  4. The results indicate that the endometrial expression of PPARgamma genes fluctuates during the estrous cycle and pregnancy.

  5. Increasing dietary DE linearly enhanced the expression of PPARgamma in adipose tissues but not skeletal muscle of Rongchang piglets.

  6. These results suggest that trans-10, cis (show CISH Proteins)-12-conjugated linoleic acid can modulate TNF-alpha (show TNF Proteins) production and NF-kappa B (show NFKB1 Proteins) expression by a PPARgamma-dependent pathway in porcine peripheral blood mononuclear cells.

  7. The results indicated that PPARgamma gene was significantly associated with litter size in pigs.

  8. Results indicated that PPARgamma is an essential regulatory factor for the transcriptional activity of ERp44 (show ERP44 Proteins), which in turn controls the secretion of adiponectin (show ADIPOQ Proteins).

  9. Endothelium on the pathosusceptible side of the aortic valve leaflet is responds to hypercholesterolemia with activation of a PPAR-gamma pathway.

  10. PPAR profiles in bladder smooth muscle (BSM) may contribute to the susceptibility of BSM to lipotoxicity in the metabolic syndrome.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. An Asp7Gly substitution in PPARG is associated with adiposity.

  2. upregulation of PPARgamma was observed in the backfat tissue of Lilu cattle with increasing age

  3. Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta (show CEBPB Proteins) and PPAR-gamma gene expression in differentiated myoblasts and an increase in GPR43 (show FFAR2 Proteins) gene expression in adipocytes.

  4. A potential association of an single nucleotide polymorphism (72472 GT in exon7) of the bovine PPAR-gamma gene with carcass and meat quality traits, was evaluated.

  5. study demonstrates the co-expression of DLX3 (show DLX3 Proteins), PPARG and SP1 (show SP1 Proteins) in trophoblast binucleated cell(BNC)nuclei; this suggests a possible role of these transcription factors through BNC specific genes at the time of pre-placental differentiation

  6. Single nucleotide polymorphisms in coding region of the PPARgamma gene, were examined.

  7. oxidative stress attenuates PPAR gamma expression and activity in vascular endothelial cells

  8. The effects of dietary fat components on the expression of PPAR-gamma AND PPAR-gamma coactivator 1 in cultured bovine preadipocytes are reported.

  9. Intramammary infection elicited a strong transcriptomic response, leading to potent activation of pro-inflammatory pathways that were associated with a marked inhibition of lipid synthesis, stress-activated kinase signaling cascades, and PPAR (show PPARA Proteins) signaling.

  10. PPARgamma1 has bifunctional properties in the regulation of KDR gene expression mediated via interaction with both Sp1 and Sp3

Rhesus Monkey Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. study found PPAR-gamma expression was prominent in the subthalamic nucleus, oculomotor nucleus, ventral tegmental nucleus, and to a lesser extent, in the putamen; 3 or 12 months after MPTP (show PTPN2 Proteins), only the lesioned putamen had increased PPAR-gamma

  2. Aleglitazar, a dual PPARalpha (show PPARA Proteins)/gamma agonist, has beneficial effects on both lipid and glucose parameters in a primate model of the metabolic syndrome.

Rabbit Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. siRNA targeting PPARgamma gene can inhibit adipogenic differentiation of BMSCs and prevent steroid-induced osteonecrosis in rabbit.

  2. vitamin E supplementation affords protection by decreasing MMP-1 (show MMP1 Proteins) and increasing PPARg, GSTa (show GSTa2 Proteins), and ABCA1 (show ABCA1 Proteins) levels in aortae of rabbits fed a cholesterol-rich diet

  3. Telmisartan improves microvascular dysfunction during myocardial ischemia/reperfusion injury via the PPARgamma pathway.

  4. PPARgamma plays a luteotropic role in pseudopregnant rabbits, through PTGS2 (show PTGS2 Proteins) down-regulation and 3beta-HSD (show HAL Proteins) up-regulation, with a consequent PGF2alpha decrease and progesterone increase.

  5. In an animal model of atherosclerosis, the expression of PPAR-gamma is upregulated following atorvastatin administration.

  6. Tongxinluo can inhibit the expression of MMP-3 (show MMP3 Proteins) and 9 and increase the expression of PPARgamma in atherosclerotic rabbits.

  7. Niacin Reduces serum level and adipose mRNA expression of leptin (show LEP Proteins) and up-regulates PPARgamma and CD36 (show CD36 Proteins) mRNA expression in hypercholesterolemic rabbits.

  8. Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase (show PIK3CA Proteins), Akt (show AKT1 Proteins), and eNOS (show NOS3 Proteins) pathway in a rabbit model of myocardial infarction.

PPARG Protein Profile

Protein Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Alternative names and synonyms associated with PPARG

  • peroxisome proliferator-activated receptor gamma (PPARG)
  • peroxisome proliferator activated receptor gamma (Pparg)
  • peroxisome proliferator-activated receptor gamma (Pparg)
  • peroxisome proliferator-activated receptor gamma (pparg)
  • PPAR gamma 3 (LOC100008892)
  • CIMT1 protein
  • GLM1 protein
  • NR1C3 protein
  • PPAR-GAMMA protein
  • PPAR-gamma2 protein
  • PPARG protein
  • PPARG1 protein
  • PPARG2 protein
  • PPAR gamma protein
  • PPARGAMMA protein
  • PPARgamma2 protein
  • xPPAR-gamma protein

Protein level used designations for PPARG

peroxisome proliferator activated receptor gamma , peroxisome proliferative activated receptor gamma , peroxisome proliferator-activated receptor gamma , peroxisome proliferator activator receptor gamma , nuclear receptor subfamily 1 group C member 3 , peroxisome proliferator activated receptor gamma 2 , peroxisome proliferator activated receptor gamma 4 , Nuclear receptor subfamily 1 group C member 3 , PPAR gamma , PPAR-gamma , peroxisome proliferator-activated nuclear receptor gamma variant 1 , peroxisome proliferator-activated receptor gamma 1 , peroxisome proliferator activator receptor, gamma , PPAR gamma 2 , xPPAR gamma , peroxisome proliferative activated receptor, gamma , peroxisome proliferator-activated receptor gamma 2 , peroxisome proliferator-activated receptor gamma 1-a , peroxisome proliferator-activated receptor gamma 1-b , PPAR gamma 1 , peroxisome proliferator activated receptor gamma-1 , peroxisome proliferator-activated receptor-gamma

443513 Ovis aries
460178 Pan troglodytes
100049014 Felis catus
100581046 Nomascus leucogenys
19016 Mus musculus
100689245 Cricetulus griseus
5468 Homo sapiens
25664 Rattus norvegicus
397769 Xenopus laevis
373928 Gallus gallus
403606 Canis lupus familiaris
397671 Sus scrofa
281993 Bos taurus
100729138 Cavia porcellus
574190 Macaca mulatta
100008892 Oryctolagus cuniculus
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