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Browse our PPARG Proteins (PPARG)

Full name:
Peroxisome Proliferator-Activated Receptor gamma Proteins (PPARG)
On www.antibodies-online.com are 45 Peroxisome Proliferator-Activated Receptor gamma (PPARG) Proteins from 14 different suppliers available. Additionally we are shipping PPARG Antibodies (304) and PPARG Kits (70) and many more products for this protein. A total of 436 PPARG products are currently listed.
Synonyms:
CIMT1, GLM1, NR1C3, PPAR-GAMMA, PPAR-gamma2, PPARG, PPARG1, PPARG2, PPAR gamma, PPARGAMMA, PPARgamma2, xPPAR-gamma
list all proteins Gene Name GeneID UniProt
PPARG 19016 P37238
PPARG 5468 P37231
PPARG 25664 O88275

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PPARG Proteins (PPARG) by Origin

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Top referenced PPARG Proteins

  1. Human PPARG Protein expressed in Escherichia coli (E. coli) - ABIN667157 : Berger, Moller: The mechanisms of action of PPARs. in Annual review of medicine 2002 (PubMed)
    Show all 2 references for ABIN667157

More Proteins for PPARG Interaction Partners

Mouse (Murine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. Study suggests that D-allose may has therapeutic potential against brain ischemia reperfusion injury through attenuating blood brain barrier disruption and the inflammatory response via PPARgamma-dependent regulation of NF-kappaB (show NFKB1 Proteins).

  2. reduced lung levels of PPARgamma and increased levels of microRNA-27a (miR (show MLXIP Proteins)-27a), v-ets (show ETS1 Proteins) avian erythroblastosis virus E26 oncogene (show RAB1A Proteins) homolog 1 (ETS1 (show ETS1 Proteins)), endothelin-1 (ET-1 (show EDN1 Proteins)), and markers of endothelial dysfunction (platelet/endothelial cell adhesion molecule 1 (show PECAM1 Proteins) and E selectin (show SELE Proteins)).

  3. Alcohol-induced Toll-like receptor 4 (show TLR4 Proteins) endocytosis was reversed by PPARgamma activation.

  4. endogenous KLF4 (show KLF4 Proteins) and Krox20 (show EGR2 Proteins) are dispensable for adipogenesis in culture and for brown adipose tissue development in mice. In contrast, the master adipogenic transcription factor peroxisome proliferator-activated receptor gamma (PPARgamma) is essential.

  5. These results suggested that HD-14 served as an activator of PPAR-gamma and that the JAK1 (show JAK1 Proteins)/STAT1 (show STAT1 Proteins) signaling pathway may be involved in the progress of inflammation.

  6. These data demonstrate that genetic deletion of sEH (show EPHX2 Proteins) resulted in an altered oxylipin profile, which may have led to an enhanced CRH (show CRH Proteins) response.

  7. SHBG (show SHBG Proteins) plasma levels regulate hepatic lipogenesis through PPARgamma modulation.

  8. Leukocyte overexpression of intracellular NAMPT (show NAMPT Proteins) attenuates atherosclerosis by regulating PPARgamma-dependent monocyte differentiation and function.

  9. Neuronal PPARgamma is required for optimal female fertility but is also involved in the adverse effects of diet-induced obesity by creating leptin (show LEP Proteins) resistance potentially through induction of the repressor Socs3 (show SOCS3 Proteins).

  10. These results suggest that the major role of PPARgamma is to enhance pathways critical in uptake and reesterification of extrahepatic fatty acids.

Human Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. reduced lung levels of PPARgamma and increased levels of microRNA-27a (miR (show MLXIP Proteins)-27a), v-ets (show ETS1 Proteins) avian erythroblastosis virus E26 oncogene (show RAB1A Proteins) homolog 1 (ETS1 (show ETS1 Proteins)), endothelin-1 (ET-1 (show EDN1 Proteins)), and markers of endothelial dysfunction (platelet/endothelial cell adhesion molecule 1 (show PECAM1 Proteins) and E selectin (show SELE Proteins)).

  2. Alcohol-induced Toll-like receptor 4 (show TLR4 Proteins) endocytosis was reversed by PPARgamma activation.

  3. SHBG (show SHBG Proteins) plasma levels regulate hepatic lipogenesis through PPARgamma modulation.

  4. Caspase-1 (show CASP1 Proteins)-mediated downregulation of PPARgamma was important in the late stage of monocyte-macrophage differentiation; however, PPARgamma protein levels had little effect on the early stage differentiation.

  5. Taken together, these results indicate that ATRA-enhanced expression of DOK1 (show DOK1 Proteins) activates PPARgamma leading to inhibition of cell proliferation and enhancement of cell apoptosis in MCF-7 cell.

  6. The study results were suggestive of a positive association between Gly972Arg of IRS1 (show IRS1 Proteins) and PCOS in the south Indian population, while INS (show INS Proteins), IRS2 (show IRS2 Proteins), PPAR-G (show ARF6 Proteins) and CAPN10 (show CAPN10 Proteins) failed to show any association with PCOS in our studied population.

  7. Human lung fibroblasts activated with proinflammatory IL-1beta (show IL1B Proteins) or cigarette smoke extract produce functional PPARgamma ligands; this phenomenon is temporally regulated, COX-2- and lipocalin (show APOD Proteins)-type PGD (show PGD Proteins) synthase-dependent.

  8. selected 9 nsSNPs variants of PPARgamma ligand binding domain, V290M (show PPOX Proteins), R357A, R397C, F360L, P467L, Q286P, R288H, E324K and E460K; investigated effects of a single amino acid change on thermodynamic stability, spectral properties, and molecular dynamics; nsSNPs PPARgamma variants show alteration of dynamics and tertiary contacts that impair the correct reciprocal positioning of helices 3 and 12, important for PPARgamma f...

  9. TGF-beta (show TGFB1 Proteins)-treated fibroblasts contained SMAD (show SMAD1 Proteins) complexes that activated a SMAD (show SMAD1 Proteins) target gene in addition to those repressing PPARG transcription, the first finding of such dual activity within the same cell. These findings describe in detail novel mechanisms by which TGF-beta (show TGFB1 Proteins) represses PPARG transcription, thereby facilitating its own pro-fibrotic activity

  10. PPARg-induced miR (show MLXIP Proteins)-124 inhibits the production of pro-inflammatory cytokines in severe sepsis.

Pig (Porcine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. The regulatory role of microRNA miR (show MYLIP Proteins)-27b-3p on peroxisome proliferator-activated receptor-gamma (PPARgamma) was confirmed by their inversed expression patterns in oocytes: [miR (show MYLIP Proteins)-27b-3p]

  2. an Enhancer box and a binding site for a cooperative co-activator of MyoD (show MYOD1 Proteins) are present in the promoter region of porcine PPARgamma.

  3. The data suggest that there is local cooperation between resistin (show RETN Proteins) and PPARgamma expression in the porcine ovary. Resistin (show RETN Proteins) significantly increased the expression of PPARgamma, whereas PPARgamma decreased resistin (show RETN Proteins) expression; thus, PPARgamma is a new key regulator of resistin (show RETN Proteins) expression and function.

  4. Therefore, this study demonstrated that the different regulatory adipogenic roles of MSTN (show MSTN Proteins) in ADSCs and MSCs act by differentially regulating PPARgamma and MyoD (show MYOD1 Proteins) expression.

  5. PGRN (show GRN Proteins) inhibits adipogenesis in porcine preadipocytes partially through ERK (show MAPK1 Proteins) activation mediated PPARgamma phosphorylation.

  6. Resveratrol activated sirtuin 1 (Sirt1 (show SIRT1 Proteins)) gene expression and increased adipose triglyceride lipase (ATGL (show PNPLA2 Proteins)) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 (show SIRT1 Proteins) regulation pattern for PPARgamma to that of ATGL (show PNPLA2 Proteins) in adipocytes.

  7. The results indicate that the endometrial expression of PPARgamma genes fluctuates during the estrous cycle and pregnancy.

  8. Increasing dietary DE linearly enhanced the expression of PPARgamma in adipose tissues but not skeletal muscle of Rongchang piglets.

  9. These results suggest that trans-10, cis (show CISH Proteins)-12-conjugated linoleic acid can modulate TNF-alpha (show TNF Proteins) production and NF-kappa B (show NFKB1 Proteins) expression by a PPARgamma-dependent pathway in porcine peripheral blood mononuclear cells.

  10. The results indicated that PPARgamma gene was significantly associated with litter size in pigs.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. PPARgamma is a positive regulator of milk fat synthesis in dairy cow mammary epithelial cells.

  2. An Asp7Gly substitution in PPARG is associated with adiposity.

  3. upregulation of PPARgamma was observed in the backfat tissue of Lilu cattle with increasing age

  4. Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta (show CEBPB Proteins) and PPAR-gamma gene expression in differentiated myoblasts and an increase in GPR43 (show FFAR2 Proteins) gene expression in adipocytes.

  5. A potential association of an single nucleotide polymorphism (72472 GT in exon7) of the bovine PPAR-gamma gene with carcass and meat quality traits, was evaluated.

  6. study demonstrates the co-expression of DLX3 (show DLX3 Proteins), PPARG and SP1 (show SP1 Proteins) in trophoblast binucleated cell(BNC)nuclei; this suggests a possible role of these transcription factors through BNC specific genes at the time of pre-placental differentiation

  7. Single nucleotide polymorphisms in coding region of the PPARgamma gene, were examined.

  8. oxidative stress attenuates PPAR gamma expression and activity in vascular endothelial cells

  9. The effects of dietary fat components on the expression of PPAR-gamma AND PPAR-gamma coactivator 1 in cultured bovine preadipocytes are reported.

  10. Intramammary infection elicited a strong transcriptomic response, leading to potent activation of pro-inflammatory pathways that were associated with a marked inhibition of lipid synthesis, stress-activated kinase signaling cascades, and PPAR (show PPARA Proteins) signaling.

Rhesus Monkey Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. study found PPAR-gamma expression was prominent in the subthalamic nucleus, oculomotor nucleus, ventral tegmental nucleus, and to a lesser extent, in the putamen; 3 or 12 months after MPTP (show PTPN2 Proteins), only the lesioned putamen had increased PPAR-gamma

  2. Aleglitazar, a dual PPARalpha (show PPARA Proteins)/gamma agonist, has beneficial effects on both lipid and glucose parameters in a primate model of the metabolic syndrome.

Rabbit Peroxisome Proliferator-Activated Receptor gamma (PPARG) interaction partners

  1. siRNA targeting PPARgamma gene can inhibit adipogenic differentiation of BMSCs and prevent steroid-induced osteonecrosis in rabbit.

  2. vitamin E supplementation affords protection by decreasing MMP-1 (show MMP1 Proteins) and increasing PPARg, GSTa (show GSTa2 Proteins), and ABCA1 (show ABCA1 Proteins) levels in aortae of rabbits fed a cholesterol-rich diet

  3. Telmisartan improves microvascular dysfunction during myocardial ischemia/reperfusion injury via the PPARgamma pathway.

  4. PPARgamma plays a luteotropic role in pseudopregnant rabbits, through PTGS2 (show PTGS2 Proteins) down-regulation and 3beta-HSD (show HAL Proteins) up-regulation, with a consequent PGF2alpha decrease and progesterone increase.

  5. In an animal model of atherosclerosis, the expression of PPAR-gamma is upregulated following atorvastatin administration.

  6. Tongxinluo can inhibit the expression of MMP-3 (show MMP3 Proteins) and 9 and increase the expression of PPARgamma in atherosclerotic rabbits.

  7. Niacin Reduces serum level and adipose mRNA expression of leptin (show LEP Proteins) and up-regulates PPARgamma and CD36 (show CD36 Proteins) mRNA expression in hypercholesterolemic rabbits.

  8. Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase (show PIK3CA Proteins), Akt (show AKT1 Proteins), and eNOS (show NOS3 Proteins) pathway in a rabbit model of myocardial infarction.

PPARG Protein Profile

Protein Summary

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Alternative names and synonyms associated with PPARG

  • peroxisome proliferator-activated receptor gamma (PPARG)
  • peroxisome proliferator activated receptor gamma (Pparg)
  • peroxisome proliferator-activated receptor gamma (Pparg)
  • peroxisome proliferator-activated receptor gamma (pparg)
  • PPAR gamma 3 (LOC100008892)
  • CIMT1 protein
  • GLM1 protein
  • NR1C3 protein
  • PPAR-GAMMA protein
  • PPAR-gamma2 protein
  • PPARG protein
  • PPARG1 protein
  • PPARG2 protein
  • PPAR gamma protein
  • PPARGAMMA protein
  • PPARgamma2 protein
  • xPPAR-gamma protein

Protein level used designations for PPARG

peroxisome proliferator activated receptor gamma , peroxisome proliferative activated receptor gamma , peroxisome proliferator-activated receptor gamma , peroxisome proliferator activator receptor gamma , nuclear receptor subfamily 1 group C member 3 , peroxisome proliferator activated receptor gamma 2 , peroxisome proliferator activated receptor gamma 4 , Nuclear receptor subfamily 1 group C member 3 , PPAR gamma , PPAR-gamma , peroxisome proliferator-activated nuclear receptor gamma variant 1 , peroxisome proliferator-activated receptor gamma 1 , peroxisome proliferator activator receptor, gamma , PPAR gamma 2 , xPPAR gamma , peroxisome proliferative activated receptor, gamma , peroxisome proliferator-activated receptor gamma 2 , peroxisome proliferator-activated receptor gamma 1-a , peroxisome proliferator-activated receptor gamma 1-b , PPAR gamma 1 , peroxisome proliferator activated receptor gamma-1 , peroxisome proliferator-activated receptor-gamma

GENE ID SPECIES
443513 Ovis aries
460178 Pan troglodytes
100049014 Felis catus
100581046 Nomascus leucogenys
19016 Mus musculus
100689245 Cricetulus griseus
5468 Homo sapiens
25664 Rattus norvegicus
397769 Xenopus laevis
373928 Gallus gallus
403606 Canis lupus familiaris
397671 Sus scrofa
281993 Bos taurus
100729138 Cavia porcellus
574190 Macaca mulatta
100008892 Oryctolagus cuniculus
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