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Browse our CYP24A1 (CYP24A1) ELISA Kits

Full name:
Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 ELISA Kits (CYP24A1)
On www.antibodies-online.com are 13 Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) ELISA Kits from 6 different suppliers available. Additionally we are shipping CYP24A1 Antibodies (89) and CYP24A1 Proteins (6) and many more products for this protein. A total of 116 CYP24A1 products are currently listed.
Synonyms:
24-OHase, 25-hydroxyvitaminD324-hydroxylase, CP24, CP450CC24, Cyp24, HCAI, P450-CC24, VITD12
list all ELISA KIts Gene Name GeneID UniProt
CYP24A1 1591 Q07973
CYP24A1 13081 Q64441
Rat CYP24A1 CYP24A1 25279 Q09128

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Human Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) interaction partners

  1. suppression of vitamin D metabolism following knockdown of CYP24A1 significantly reduced tumor growth in vivo. These data provide substantial evidence for a pro-survival and stimulatory oncogenic effect of CYP24A1 in breast carcinoma cells

  2. confirms that CYP24A1 plays a causal role in some but not all cases of IIH (64%); (2) expands the spectrum of known CYP24A1 pathogenic mutations; (3) describes 2 hotspots detected in 50% of all Italian cases; and (4) emphasizes the importance of recognition and genetic diagnosis of CYP24A1 defects in infantile as well as adult hypercalcemia

  3. Suggest Cyp24a1 promoter SNP rs2248359 is associated with severe atopic dermatitis.

  4. most heterozygous CYP24A1 mutation carriers have a normal 25OHD/24,25(OH)2D ratio, are usually asymptomatic and have a normal skeletal status but may possibly be at increased risk of nephrocalcinosis

  5. CYP24A1 expression is closely associated with colorectal cancer progression, and it might be a novel prognostic biomarker for CRC (show CALR ELISA Kits).

  6. The CYP24A1 SNP rs927650 may be related to both circulating blood concentrations of 25-hydroxyvitamin D as well as to odds of recurrent colorectal neoplasia.

  7. A definite alteration was seen in vitamin D3-inactivating CYP24A1 gene activity in papillary thyroid carcinoma compared to their normal tissues on a relatively large patient population.

  8. Vitamin D-binding protein (show GC ELISA Kits) SNPs are associated with prostate cancer; low 25(OH)D metabolism score and CYP24A1 and CYP27B1 (show CYP27B1 ELISA Kits) variants are associated with grade

  9. Breast cancer risk may be associated with specific vitamin D-related polymorphisms, particularly CYP24A1 and VDR (show CYP27B1 ELISA Kits).

  10. CYP24A1 biallelic mutations are frequently found in patients presenting with hypercalcemia, low PTH (show PTH ELISA Kits), and renal disease. Haploinsufficiency is not associated with CYP24A1 deficiency.

Mouse (Murine) Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) interaction partners

  1. results link CYP24 activity to the pathophysiology of FGF23 (show FGF23 ELISA Kits)-dependent renal phosphate wasting states and implicate pharmacologic CYP24 inhibition as a therapeutic adjunct for their treatment.

  2. Gsalpha is required in proximal tubules for suppressing renal vitamin D 24-hydroxylase mRNA levels and for maintaining normal serum 1,25(OH)2D.

  3. Data suggest that control of CYP24A1 increase during diabetes has a beneficial effect on senescence induction and caspase-3 (show CASP3 ELISA Kits) increased expression.

  4. the mechanism through which 1,25(OH)(2)D(3) induces the CYP24A1 enzyme

  5. The expression of vitamin D 24-hydroxylase gene was directly regulated by serum calcium rather than 25-hydroxyvitamin D 1 alpha-hydroxylase.

  6. Results show that Inhibition of 24-OHase activity modulates serum calcitriol PK in normal C3H/HeJ mice.

  7. Cyp24a1 deficiency delays fracture repair and strongly suggest that vitamin D metabolites hydroxylated at position 24, such as 24,25(OH)2D3, play an important role in the mechanisms leading to normal fracture hea (show TTC7A ELISA Kits)

  8. 1,25(OH)2D is the preferred substrate for CYP24 in murine kidney mitochondria.

  9. findings demonstrate that regulation of both the 25-hydroxyvitamin D-1 alpha-hydroxylase and 25-hydroxyvitamin D-24-hydroxylase genes by phosphorus is disordered in hypophosphatemic mice at the level of renal mRNA expression

  10. the absence of CYP24A1 or vitamin D receptor (show VDR ELISA Kits) retards catabolism of 1alpha,25(OH)2D3 and 25(OH)D3

CYP24A1 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CYP24A1

  • cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1) Elisa Kit
  • cytochrome P450, family 24, subfamily a, polypeptide 1 (Cyp24a1) Elisa Kit
  • 24-OHase Elisa Kit
  • 25-hydroxyvitaminD324-hydroxylase Elisa Kit
  • CP24 Elisa Kit
  • CP450CC24 Elisa Kit
  • Cyp24 Elisa Kit
  • HCAI Elisa Kit
  • P450-CC24 Elisa Kit
  • VITD12 Elisa Kit

Protein level used designations for CYP24A1

1,25-@dihydroxyvitamin D3 24-hydroxylase , 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial , 24-OHase , cytochrome P450 24A1 , cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) , cytochrome P450-CC24 , exo-mitochondrial protein , vitamin D 24-hydroxylase , vitamin D(3) 24-hydroxylase , 25-hydroxyvitamin D-24-hydroxylase , cytochrome P450, 24 , cytochrome P450, 24a1 , 24R-Ohase , 25-hydroxyvitamin D3 24-hydroxylase , Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase) , P450-CC24 , cytochrome P450, subfamily 24 , 25-hydroxyvitamin D3-24-hydroxylase

GENE ID SPECIES
1591 Homo sapiens
13081 Mus musculus
25279 Rattus norvegicus
395827 Gallus gallus
485935 Canis lupus familiaris
397145 Sus scrofa
540080 Bos taurus
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