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Browse our anti-Steroid 5 alpha-Reductase 3 (SRD5A3) Antibodies

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anti-Steroid 5 alpha-Reductase 3 Antibodies (SRD5A3)
On are 23 Steroid 5 alpha-Reductase 3 (SRD5A3) Antibodies from 7 different suppliers available. Additionally we are shipping Steroid 5 alpha-Reductase 3 Proteins (3) and many more products for this protein. A total of 29 Steroid 5 alpha-Reductase 3 products are currently listed.
1110025P14Rik, A430076C09, AV364670, AW987574, CDG1P, CDG1Q, D730040M03Rik, H5ar, KRIZI, RGD1308828, S5AR 3, Srd5a2l, SRD5A2L1, SRD5alpha3
list all antibodies Gene Name GeneID UniProt
SRD5A3 79644 Q9H8P0
SRD5A3 57357 Q9WUP4
SRD5A3 305291 Q5RJM1

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Most Popular Reactivities for anti-Steroid 5 alpha-Reductase 3 (SRD5A3) Antibodies

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All available anti-Steroid 5 alpha-Reductase 3 Antibodies

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Top referenced anti-Steroid 5 alpha-Reductase 3 Antibodies

  1. Human Polyclonal SRD5A3 Primary Antibody for WB - ABIN4893204 : Sánchez, Castro, Torres, Ortega: Effects of different ethanol-administration regimes on mRNA and protein levels of steroid 5α-reductase isozymes in prefrontal cortex of adolescent male rats. in Psychopharmacology 2014 (PubMed)
    Show all 2 references for ABIN4893204

  2. Cow (Bovine) Polyclonal SRD5A3 Primary Antibody for WB - ABIN2783928 : Uemura, Tamura, Chung, Honma, Okuyama, Nakamura, Nakagawa: Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer. in Cancer science 2007 (PubMed)

More Antibodies against Steroid 5 alpha-Reductase 3 Interaction Partners

Human Steroid 5 alpha-Reductase 3 (SRD5A3) interaction partners

  1. Although 4-dione is the main source of 5alpha-dihydrotestosterone in human preadipocytes, production of this steroid by 5 alpha-reductase isoenzymes (SRD5A1 (show SRD5A1 Antibodies), 2 and 3) mediates the inhibitory effect of both 4-dione and testosterone on preadipocyte differentiation.

  2. Mutations in the SRD5A3 gene may cause early-onset retinal dystrophy (show MERTK Antibodies), a previously underdescribed feature of the SRD5A3-CDG disorder that is progressive and may lead to serious visual impairment.

  3. the spectrum of phenotypes resulting from SRD5A3 mutations and the clinical variability of SRD5A3-CDG

  4. Findings suggest that overexpression of 5alpha-reductase, through a higher inactivation of cortisol in the liver, could have a protective role in preserving hepatic sensitivity to insulin (show INS Antibodies).

  5. Next generation sequencing identified a homozygous frameshift mutation (c.203dupC; p.Phe69LeufsX2) SRD5A3 as the disease-causing change in Kahrizi syndrome.

  6. A novel syndrome is identified in families with cerebellar ataxia (show USP14 Antibodies) and congenital eye malformations due to steroid 5 alpha-reductase type 3 disorders of glycosylation.

  7. Study of a large consanguineous Emirati family showed that loss of function mutations of the SRD5A3 gene cause a multisystemic syndrome with eye malformations, cerebellar vermis hypoplasia, and psychomotor delay.

  8. Findings indicate that a novel type 3 5 alpha-steroid reductase, SRD5A3, is associated with DHT production and maintenance of androgen-androgen receptor (show AR Antibodies)-pathway activation in prostate cancer.

Mouse (Murine) Steroid 5 alpha-Reductase 3 (SRD5A3) interaction partners

  1. Srd5a3 mutation is lethal in mouse and results in an activation of the unfolded protein response pathway.

Steroid 5 alpha-Reductase 3 (SRD5A3) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq.

Alternative names and synonyms associated with Steroid 5 alpha-Reductase 3 (SRD5A3)

  • steroid 5 alpha-reductase 3 (SRD5A3) antibody
  • steroid 5 alpha-reductase 3 (Srd5a3) antibody
  • steroid 5 alpha-reductase 3 (srd5a3) antibody
  • 1110025P14Rik antibody
  • A430076C09 antibody
  • AV364670 antibody
  • AW987574 antibody
  • CDG1P antibody
  • CDG1Q antibody
  • D730040M03Rik antibody
  • H5ar antibody
  • KRIZI antibody
  • RGD1308828 antibody
  • S5AR 3 antibody
  • Srd5a2l antibody
  • SRD5A2L1 antibody
  • SRD5alpha3 antibody

Protein level used designations for SRD5A3

3-oxo-5-alpha-steroid 4-dehydrogenase 3 , S5AR 3 , SR type 3 , polyprenol reductase , probable polyprenol reductase , H5AR , steroid 5 alpha-reductase 2 like , steroid 5 alpha-reductase 2-like; H5AR gene; steroid 5 alpha-reductase 2 like , steroid 5-alpha-reductase 3 , Probable polyprenol reductase , Steroid 5-alpha-reductase 3

79644 Homo sapiens
482155 Canis lupus familiaris
535834 Bos taurus
57357 Mus musculus
305291 Rattus norvegicus
379123 Xenopus laevis
100463734 Ailuropoda melanoleuca
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