You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our Steroid 5 alpha-Reductase 3 Proteins (SRD5A3)

Full name:
Steroid 5 alpha-Reductase 3 Proteins (SRD5A3)
On are 3 Steroid 5 alpha-Reductase 3 (SRD5A3) Proteins from 2 different suppliers available. Additionally we are shipping Steroid 5 alpha-Reductase 3 Antibodies (24) and many more products for this protein. A total of 30 Steroid 5 alpha-Reductase 3 products are currently listed.
1110025P14Rik, A430076C09, AV364670, AW987574, CDG1P, CDG1Q, D730040M03Rik, H5ar, KRIZI, RGD1308828, S5AR 3, Srd5a2l, SRD5A2L1, SRD5alpha3
list all proteins Gene Name GeneID UniProt
SRD5A3 79644 Q9H8P0
SRD5A3 57357 Q9WUP4
Rat SRD5A3 SRD5A3 305291 Q5RJM1

Show all synonyms

Steroid 5 alpha-Reductase 3 Proteins (SRD5A3) by Origin

Select your origin of interest

More Proteins for Steroid 5 alpha-Reductase 3 Interaction Partners

Human Steroid 5 alpha-Reductase 3 (SRD5A3) interaction partners

  1. the spectrum of phenotypes resulting from SRD5A3 mutations and the clinical variability of SRD5A3-CDG

  2. Findings suggest that overexpression of 5alpha-reductase, through a higher inactivation of cortisol in the liver, could have a protective role in preserving hepatic sensitivity to insulin (show INS Proteins).

  3. Next generation sequencing identified a homozygous frameshift mutation (c.203dupC; p.Phe69LeufsX2) SRD5A3 as the disease-causing change in Kahrizi syndrome.

  4. A novel syndrome is identified in families with cerebellar ataxia (show USP14 Proteins) and congenital eye malformations due to steroid 5 alpha-reductase type 3 disorders of glycosylation.

  5. Study of a large consanguineous Emirati family showed that loss of function mutations of the SRD5A3 gene cause a multisystemic syndrome with eye malformations, cerebellar vermis hypoplasia, and psychomotor delay.

  6. Findings indicate that a novel type 3 5 alpha-steroid reductase, SRD5A3, is associated with DHT production and maintenance of androgen-androgen receptor (show AR Proteins)-pathway activation in prostate cancer.

Mouse (Murine) Steroid 5 alpha-Reductase 3 (SRD5A3) interaction partners

  1. Srd5a3 mutation is lethal in mouse and results in an activation of the unfolded protein response pathway.

Steroid 5 alpha-Reductase 3 (SRD5A3) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq.

Alternative names and synonyms associated with Steroid 5 alpha-Reductase 3 (SRD5A3)

  • steroid 5 alpha-reductase 3 (SRD5A3)
  • steroid 5 alpha-reductase 3 (Srd5a3)
  • steroid 5 alpha-reductase 3 (srd5a3)
  • 1110025P14Rik protein
  • A430076C09 protein
  • AV364670 protein
  • AW987574 protein
  • CDG1P protein
  • CDG1Q protein
  • D730040M03Rik protein
  • H5ar protein
  • KRIZI protein
  • RGD1308828 protein
  • S5AR 3 protein
  • Srd5a2l protein
  • SRD5A2L1 protein
  • SRD5alpha3 protein

Protein level used designations for SRD5A3

3-oxo-5-alpha-steroid 4-dehydrogenase 3 , S5AR 3 , SR type 3 , polyprenol reductase , probable polyprenol reductase , H5AR , steroid 5 alpha-reductase 2 like , steroid 5 alpha-reductase 2-like; H5AR gene; steroid 5 alpha-reductase 2 like , steroid 5-alpha-reductase 3 , Probable polyprenol reductase , Steroid 5-alpha-reductase 3

79644 Homo sapiens
482155 Canis lupus familiaris
535834 Bos taurus
57357 Mus musculus
305291 Rattus norvegicus
379123 Xenopus laevis
100463734 Ailuropoda melanoleuca
Selected quality suppliers for Steroid 5 alpha-Reductase 3 Proteins (SRD5A3)
Did you look for something else?