Browse our EML2 Proteins (EML2)

Full name:
Echinoderm Microtubule Associated Protein Like 2 Proteins (EML2)
On are 5 Echinoderm Microtubule Associated Protein Like 2 (EML2) Proteins from 3 different suppliers available. Additionally we are shipping EML2 Antibodies (36) and EML2 Kits (10) and many more products for this protein. A total of 52 EML2 products are currently listed.
1600029N02Rik, ELP70, Emap, Emap-2, EMAP2, EMAPII, Eml1, HLD3, p43, SCYE1
list all proteins Gene Name GeneID UniProt
EML2 9255 Q12904
EML2 72205 Q7TNG5
EML2 192360 Q6P6T4

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EML2 Proteins (EML2) by Origin

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More Proteins for EML2 Interaction Partners

Human Echinoderm Microtubule Associated Protein Like 2 (EML2) interaction partners

  1. p43 (show AIMP1 Proteins) induces both the mRNA and protein expression of IP-10 (show CXCL10 Proteins).

  2. Data indicate that AIMP1 (show AIMP1 Proteins) downregulation using siRNA is a novel tool to restore TGF-beta (show TGFB1 Proteins) signaling and thereby increases the chondrogenic potential of dedifferentiated/degenerated chondrocytes.

  3. two homozygous missense variants, p.(Gly299Arg) and p.(Val176Gly), in the gene AIMP1 (show AIMP1 Proteins) that co-segregated with the phenotype, are reported.

  4. AIMp1 (show AIMP1 Proteins) promotes the proliferation and migration of fibroblasts/endothelial cells and importantly, pro-inflammatory gene expression in monocytes/macrophages and dendritic cells.

  5. AIMP1 (show AIMP1 Proteins) appears to function as a novel inhibitor of PPARgamma (show PPARG Proteins) that regulates adipocyte differentiation by preventing the transcriptional activation of PPARgamma (show PPARG Proteins).

  6. Data indicate that HCV E2 glycoprotein interacts with cellular AIMP1/p43 (show AIMP1 Proteins) protein and promotes cell surface expression of membrane glycoproteins gp96 (show HSP90B1 Proteins) and transforming growth factor beta TGF-beta signaling.

  7. Data indicate that the N terminus of Pro-EMAP II binds to its C terminus, arginyl-tRNA synthetase (show RARS Proteins), and the neurofilament light subunit.

  8. We have determined crystal structures of the coiled-coils from EML2 and EML4, which describe the structural basis of both EML self-association and oncogenic EML4-ALK activation.

  9. EMAP2 is a multifunctional polypeptide with proinflammatory and antiangiogenic activity. (Review)

  10. interactions between the N-terminal domains of ArgRS (show RARS Proteins) and AIMP1 (show AIMP1 Proteins) are important for the catalytic and noncatalytic activities of ArgRS (show RARS Proteins) and for the assembly of the higher-order MSC (show MSC Proteins) protein complex with ArgRS (show RARS Proteins)-GlnRS (show QARS Proteins)-AIMP1 (show AIMP1 Proteins)

EML2 Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.

Alternative names and synonyms associated with EML2

  • aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 (AIMP1)
  • echinoderm microtubule associated protein like 2 (EML2)
  • echinoderm microtubule associated protein like 2 (Eml2)
  • 1600029N02Rik protein
  • ELP70 protein
  • Emap protein
  • Emap-2 protein
  • EMAP2 protein
  • EMAPII protein
  • Eml1 protein
  • HLD3 protein
  • p43 protein
  • SCYE1 protein

Protein level used designations for EML2

ARS-interacting multifunctional protein 1 , aminoacyl tRNA synthase complex-interacting multifunctional protein 1 , endothelial monocyte-activating polypeptide 2 , endothelial-monocyte activating polypeptide II , multisynthase complex auxiliary component p43 , multisynthetase complex auxiliary component p43 , small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) , echinoderm MT-associated protein (EMAP)-like protein 70 , echinoderm microtubule-associated protein-like 2 , microtubule-associated protein like echinoderm EMAP , EMAP-2

9255 Homo sapiens
24139 Homo sapiens
72205 Mus musculus
192360 Rattus norvegicus
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