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Further research assessing the functions and mechanisms of FIGNL1, and other homologous recombination pathway genes may disclose unique pathological characteristics of SCLC, and help identify potential therapeutic targets and biomarkers
RAD51 (show RAD51 Proteins)-binding protein fidgetin-like 1 (FIGNL1) is identified; FIGNL1 specifically interacts with RAD51 (show RAD51 Proteins) through its conserved RAD51 (show RAD51 Proteins) binding domain. Cells depleted of FIGNL1 show defective homologous recombination repair.
Fignl1 as a novel actor in mammal's male meiosis dynamics
FIGNL1, a subfamily member of the AAA (show AAAS Proteins) family of proteins, might play some regulatory role in osteoblast proliferation and differentiation.
May regulate osteoblast proliferation and differentiation (By similarity).
fidgetin-like protein 1
, fidgetin-like 1
, fidgetin-like protein 1-like