Browse our anti-RHOA (RHOA) Antibodies

Full name:
anti-Ras Homolog Gene Family, Member A Antibodies (RHOA)
On www.antibodies-online.com are 9 Ras Homolog Gene Family, Member A (RHOA) Antibodies from 2 different suppliers available. Additionally we are shipping RHOA Proteins (7) and RHOA Kits (6) and many more products for this protein. A total of 22 RHOA products are currently listed.
Synonyms:
ARH12, Arha, Arha1, Arha2, RHO1, RHO12, Rhoa, RHOH12, wu:fa66g04, wu:fb26g07, xrhoa, zgc:66058, zgc:85805
list all antibodies Gene Name GeneID UniProt
RHOA 297173  
RHOA 387 P61586
RHOA 11848 Q9QUI0

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anti-Human RHOA Antibodies:

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Top referenced anti-RHOA Antibodies

  1. Human Polyclonal RHOA Primary Antibody for IHC, ELISA - ABIN1994388 : Yeramian, Chardin, Madaule, Tavitian: Nucleotide sequence of human rho cDNA clone 12. in Nucleic acids research 1987 (PubMed)
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More Antibodies against RHOA Interaction Partners

Xenopus laevis Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Mgc's GAP activity down-regulates the active populations of RhoA and Rac1 at localized regions of epithelial cells and is necessary for successful cytokinesis and cell-cell junction structure

  2. Data show that shortly after anaphase onset oocytes and embryonic cells exhibit cortical waves of Rho activity and F-actin polymerization.

  3. CASZ1 (show CASZ1 Antibodies)/Egfl7 (show EGFL7 Antibodies)/RhoA pathway is necessary for promoting endothelial cell behaviors associated with proper vascular assembly.

  4. RhoA can be considered a component of the intracellular pattern formation system.

  5. Kazrin (show KAZ Antibodies) interacts with ARVCF (show ARVCF Antibodies)-catenin, spectrin and p190B (show ARHGAP5 Antibodies) RhoGAP (show ARHGAP1 Antibodies), and modulates RhoA activity.

  6. Morphogenesis of the primitive gut tube is generated by Rho/ROCK/myosin II-mediated endoderm rearrangements.

Human Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Data suggest that SmgGDS (show RAP1GDS1 Antibodies)-558 splice variant exhibits a fold containing tandem copies of armadillo (show PKP1 Antibodies)-repeat motifs not present in other guanine nucleotide exchange factors (GEFs); SmgGDS (show RAP1GDS1 Antibodies) harbors distinct positively and negatively charged regions, both of which play critical roles in binding to RhoA and in GEF (show SLC2A4RG Antibodies) activity. (SmgGDS (show RAP1GDS1 Antibodies) = smg (show SNRPG Antibodies) p21 (show CDKN1A Antibodies) stimulatory GDP exchange protein; RhoA = ras homolog gene family, member A (show CXCL14 Antibodies))

  2. RhoA had a positive effect on ESC proliferation, and PKN1 (show PKN1 Antibodies) activity was up-regulated by the active RhoA mutant (G14V) and suppressed by RhoA T19N. The effect of RhoA on ESC proliferation is mediated by activation of the PKN1 (show PKN1 Antibodies)-cyclin D1 (show CCND1 Antibodies) pathway in vitro.

  3. RhoA works in concert with Fmn1 to control assembly of the specialized apical actin network in multiciliated epithelial cells.

  4. a new function for Scribble (show SCRIB Antibodies) in Rho regulation that entails positioning of DLC3 (show STARD8 Antibodies) GAP activity at cell junctions in polarized epithelial cells, is reported.

  5. Mutation in RHOA gene is associated with angioimmunoblastic and other follicular helper T-cell-derived lymphomas.

  6. These results reveal a previously unidentified pathway downstream of RHO that regulates the polarity of migrating cells through Golgi reorientation in a FAM65A-, CCM3 (show PDCD10 Antibodies)- and MST3 (show STK24 Antibodies)- and MST4 (show MST4 Antibodies)-dependent manner.

  7. depletion induces phosphorylation of the microtubule-associated GEF-H1 on Ser886, and thereby promotes RhoA activity and actin stress fiber assembly.

  8. nd correlation analysis showed that miR (show MLXIP Antibodies)-200b was inversely correlated with RhoA and circ_000839 ( p = 0.012, p = 0.002, respectively), while RhoA was positively correlated with circ_000839 ( p < 0.001). Taken together, our data suggest that miR (show MLXIP Antibodies)-200b could mediate RhoA gene and circ_000839 to form endogenous competition.

  9. Low RHOA expression is associated with Basal-like Breast Cancers.

  10. Studies suggest that Rho GTPase (show RACGAP1 Antibodies) signalling is a complicated mechanism in RhoA-driven cancer cell invasive migration.

Pig (Porcine) Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Pseudorabies virus US3 expression led to RhoA phosphorylation at serine 188 to induce actin rearrangements.

  2. Data indicate that TNF-alpha (show TNF Antibodies) stimulates Rac (show AKT1 Antibodies), ADAM17/TACE (show ADAM17 Antibodies), and RhoA through the guanine nucleotide exchange factor (show ARHGEF12 Antibodies) (GEF)-H1 (show ARHGEF2 Antibodies).

  3. Contractile pulmonary arterial myocytes exhibit marked Rho-dependent actin polymerization in hypoxia, with increased active RhoA and LIMK (show LIMK1 Antibodies) phosphorylation.

  4. Results suggest that Rac1 and RhoA are regulated by TGFbeta1 (show TGFB1 Antibodies) in the process of endothelial tube formation in collagen I gels.

  5. The concentration of RhoA mRNA and activated RhoA enzyme were greater in urothelium than in detrusor. Rho kinase (show ROCK1 Antibodies) inhibitor Y-27632 showed a stronger inhibitory effect in detrusor with intact urothelium.

  6. Thrombin (show F2 Antibodies) stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1 (show F2R Antibodies), RhoA, and myocardin (show MYOCD Antibodies).

Mouse (Murine) Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Findings suggest that atorvastatin attenuates diabetes-associated renal injury by reducing reactive oxygen species (ROS (show ROS1 Antibodies)) generation, RhoA activity and normalizing Akt (show AKT1 Antibodies)/GSK3beta (show GSK3b Antibodies) signaling pathways.

  2. findings describe a novel RhoA regulatory mechanism.

  3. ANXA1 (show ANXA1 Antibodies) restores Abeta42-induced blood brain barrier disruption through inhibition of RhoA-ROCK signaling pathway

  4. study delineates a mechanism in which NCAM (show NCAM1 Antibodies) promotes ephrin-A5 (show EFNA5 Antibodies)-dependent clustering of EphA3 (show EPHA3 Antibodies) through interaction of the NCAM (show NCAM1 Antibodies) Ig2 domain and the EphA3 (show EPHA3 Antibodies) CRD (show CRX Antibodies), stimulating EphA3 (show EPHA3 Antibodies) autophosphorylation and RhoA signaling necessary for growth cone repulsion in GABAergic interneurons in vitro, which may extend to remodeling of axonal terminals of interneurons in vivo.

  5. M0 and M2 macrophages have a radically different phenotype and polarity from M1 macrophages, and that this is mirrored in dissonant response to RhoA pathway interference.

  6. the cross-talk between canonical and non-canonical signaling pathways of Wnt3A (show WNT3A Antibodies), which induces GSK-3beta (show GSK3b Antibodies) phosphorylation and beta-catenin (show CTNNB1 Antibodies) accumulation through RhoA and ROCK activation.

  7. these findings reveal that Arhgef1 functions as a negative regulator of neurite outgrowth through regulating RhoA-cofilin pathway and actin dynamics.

  8. presentation of a form of biochemical computation in dendrites involving the controlled complementation of three molecules--Rac1, RhoA and Cdc42 (show CDC42 Antibodies)--that simultaneously ensures signal specificity and primes the system for BDNF (show BDNF Antibodies)-dependent homo- and heterosynaptic plasticity

  9. The transcriptional co-activator MRTF-A (show MKL1 Antibodies) was activated by sphingosine-1-phosphate as assessed by its nuclear accumulation and induction of a RhoA/MRTF-A (show MKL1 Antibodies) luciferase reporter.

  10. In conclusion, these results indicate the sub-chronic ethanol treatment decreased the expression of RhoA in mouse corpus cavernosum

Cow (Bovine) Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. RhoA and membrane fluidity mediates the spatially polarized Src (show SRC Antibodies)/FAK (show PTK2 Antibodies) activation in response to shear stress.

  2. the Lbc (show AKAP13 Antibodies)/alpha-catulin (show CTNNAL1 Antibodies) axis participates in 5-HT (show DDC Antibodies)-induced PASMC mitogenesis and RhoA/ROCK signaling, and may be an interventional target in diseases involving vascular smooth muscle remodeling.

  3. The RhoA/ROCK signaling pathway is an important negative regulator of vascular calcification.

  4. Vascular endothelial-cadherin signals through RhoA and actin cytoskeletal and affects cell-matrix adhesion

  5. Thrombospondin has a role in inducing RhoA inactivation through FAK (show PTK2 Antibodies)-dependent signaling to stimulate focal adhesion disassembly

  6. KCl directly increased Rho and ROCK activities in a concentration-dependent fashion that paralleled closely the effect of KCl on lung smooth muscle tone and [Ca(2 (show CA2 Antibodies)+)](i), as well as the voltage-dependent Ca(2 (show CA2 Antibodies)+) currents

  7. the Rho-ROCK signal pathway contributes to VEGF-induced hyperpermeability. Myosin light-chain phosphorylation and actin stress fiber formation occur concomitantly with the increase in permeability upon VEGF stimulation.

  8. Formation of polygonal actin network in endothelial cells is a novel rhoA associated response to hypertonic stress.

  9. Cadherins, RhoA and Rac1, have important roles in mechanotransduction and that endothelial and smooth muscle cells use different mechanisms to respond to stretch.

  10. Results indicate that hypergravity induces ATP release and actin reorganization via RhoA activation and FAK (show PTK2 Antibodies) phosphorylation, thereby activating cell proliferation and migration in bovine aortic endothelial cells.

Zebrafish Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Activating Rho could be beneficial to suppress Kras mutant-induced liver malignancies.

RHOA Antigen Profile

Antigen Summary

Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA- DIAPH1 signaling pathway plays an important role in ERBB2- dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.

Alternative names and synonyms associated with RHOA

  • RSA-14-44 protein (RSA-14-44) antibody
  • ras homolog family member A (RHOA) antibody
  • ras homolog family member A (rhoa-b) antibody
  • ras homolog family member A (rhoa) antibody
  • ras homolog family member A (Rhoa) antibody
  • ras homolog family member A (rhoa-a) antibody
  • ras homolog gene family, member A (Rhoa) antibody
  • ras homolog gene family, member A (RHOA) antibody
  • ras homolog gene family, member Aa (rhoaa) antibody
  • ARH12 antibody
  • Arha antibody
  • Arha1 antibody
  • Arha2 antibody
  • RHO1 antibody
  • RHO12 antibody
  • Rhoa antibody
  • RHOH12 antibody
  • wu:fa66g04 antibody
  • wu:fb26g07 antibody
  • xrhoa antibody
  • zgc:66058 antibody
  • zgc:85805 antibody

Protein level used designations for RHOA

ras homolog gene family, member A , transforming protein RhoA , aplysia ras-related homolog A2 , Aplysia ras-related homolog 12 , h12 , oncogene RHO H12 , rho cDNA clone 12 , small GTP binding protein RhoA , plysia ras-related homolog A2 , rho1 GTP-binding protein , Rho A , Ras family member A , Rho family GTPase , aplysia ras-related homolog A , aplysia ras-related homolog A1 , ras homolog A1 , ras homolog A2 , ras homolog gene family, member A1 , ras homolog gene family, member A2 , gb , p21 , RhoA GTPase

GENE ID SPECIES
297173 Rattus norvegicus
100302078 Ovis aries
380133 Xenopus laevis
448080 Xenopus (Silurana) tropicalis
387 Homo sapiens
117273 Rattus norvegicus
403954 Canis lupus familiaris
379416 Xenopus laevis
396849 Sus scrofa
11848 Mus musculus
338049 Bos taurus
395442 Gallus gallus
406411 Danio rerio
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