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Browse our anti-RHOA (RHOA) Antibodies

Full name:
anti-Ras Homolog Gene Family, Member A Antibodies (RHOA)
On are 9 Ras Homolog Gene Family, Member A (RHOA) Antibodies from 2 different suppliers available. Additionally we are shipping RHOA Proteins (8) and RHOA Kits (5) and many more products for this protein. A total of 22 RHOA products are currently listed.
ARH12, Arha, Arha1, Arha2, RHO1, RHO12, Rhoa, RHOH12, wu:fa66g04, wu:fb26g07, xrhoa, zgc:66058, zgc:85805
list all antibodies Gene Name GeneID UniProt
RHOA 297173  
RHOA 387 P61586
RHOA 11848 Q9QUI0

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anti-Human RHOA Antibodies:

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Top referenced anti-RHOA Antibodies

  1. Human Polyclonal RHOA Primary Antibody for IHC, ELISA - ABIN1994388 : Yeramian, Chardin, Madaule, Tavitian: Nucleotide sequence of human rho cDNA clone 12. in Nucleic acids research 1987 (PubMed)
    Show all 2 references for ABIN1994388

More Antibodies against RHOA Interaction Partners

Xenopus laevis Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Mgc's GAP activity down-regulates the active populations of RhoA and Rac1 at localized regions of epithelial cells and is necessary for successful cytokinesis and cell-cell junction structure

  2. Data show that shortly after anaphase onset oocytes and embryonic cells exhibit cortical waves of Rho activity and F-actin polymerization.

  3. CASZ1 (show CASZ1 Antibodies)/Egfl7 (show EGFL7 Antibodies)/RhoA pathway is necessary for promoting endothelial cell behaviors associated with proper vascular assembly.

  4. RhoA can be considered a component of the intracellular pattern formation system.

  5. Kazrin (show KAZ Antibodies) interacts with ARVCF (show ARVCF Antibodies)-catenin, spectrin and p190B (show ARHGAP5 Antibodies) RhoGAP (show ARHGAP1 Antibodies), and modulates RhoA activity.

  6. Morphogenesis of the primitive gut tube is generated by Rho/ROCK/myosin II-mediated endoderm rearrangements.

Human Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Collectively, these findings demonstrate that stimulation of G12 (show TCF3 Antibodies) proteins is capable of promoting invasion through RhoA/ROCK-JNK (show MAPK8 Antibodies) activation.

  2. Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein (show RASA1 Antibodies) ARAP3 (show ARAP3 Antibodies).

  3. It describes acetylation as a novel mechanism of Rhoa guanine nucleotide exchange factors regulation in cell motility that can be targeted in cancer and metastasis.

  4. Panax notoginseng saponins provide neuroprotective effects in a rat model of cerebral ischemia and SH-SY5Y cells exposed to oxygen/glucose deprivation injury by inhibiting the overexpression of NgR1 (show NEUROG1 Antibodies), RhoA, and ROCK2 (show ROCK2 Antibodies).

  5. A MAPK (show MAPK1 Antibodies)-Driven Feedback Loop Suppresses Rac (show AKT1 Antibodies) Activity to Promote RhoA-Driven Cancer Cell Invasion. Our model predicted an unanticipated feedback loop, whereby Raf (show RAF1 Antibodies)/MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) signalling maintains suppression of Rac1 by inhibiting the Rac (show AKT1 Antibodies)-activating Sos1 (show SOS1 Antibodies)-Eps8 (show EPS8 Antibodies)-Abi1 (show ABI1 Antibodies) complex, allowing RhoA activity to predominate in invasive protrusions.

  6. High RHOA expression is associated with gastric cancer.

  7. RhoA is a potential target of miR (show MLXIP Antibodies)-146a.

  8. Abnormal RhoA expression in vulvar carcinoma is involved in tumor proliferation and invasion and may be a treatment target.

  9. TPM2 (show TPM2 Antibodies) appears to be commonly silenced by aberrant DNA methylation (show HELLS Antibodies) in colon cancer. TPM2 (show TPM2 Antibodies) loss is associated with RhoA activation and tumor proliferation.

  10. we found that CXCR4 (show CXCR4 Antibodies)-CXCL12 (show CXCL12 Antibodies)/AKT (show AKT1 Antibodies) axis regulates RhoA, Rac-1, and Cdc42 (show CDC42 Antibodies) to modulate cell invasion and tumor metastasis. Together, these results demonstrate a role for CXCR4 (show CXCR4 Antibodies) in ESCC metastasis and progression and suggest potential targets for therapeutic intervention.

Pig (Porcine) Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Pseudorabies virus US3 expression led to RhoA phosphorylation at serine 188 to induce actin rearrangements.

  2. Data indicate that TNF-alpha (show TNF Antibodies) stimulates Rac (show AKT1 Antibodies), ADAM17/TACE (show ADAM17 Antibodies), and RhoA through the guanine nucleotide exchange factor (show ARHGEF12 Antibodies) (GEF)-H1 (show ARHGEF2 Antibodies).

  3. Contractile pulmonary arterial myocytes exhibit marked Rho-dependent actin polymerization in hypoxia, with increased active RhoA and LIMK (show LIMK1 Antibodies) phosphorylation.

  4. Results suggest that Rac1 and RhoA are regulated by TGFbeta1 (show TGFB1 Antibodies) in the process of endothelial tube formation in collagen I gels.

  5. The concentration of RhoA mRNA and activated RhoA enzyme were greater in urothelium than in detrusor. Rho kinase (show ROCK1 Antibodies) inhibitor Y-27632 showed a stronger inhibitory effect in detrusor with intact urothelium.

  6. Thrombin (show F2 Antibodies) stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1 (show F2R Antibodies), RhoA, and myocardin (show MYOCD Antibodies).

Mouse (Murine) Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. these findings reveal that Arhgef1 functions as a negative regulator of neurite outgrowth through regulating RhoA-cofilin pathway and actin dynamics.

  2. presentation of a form of biochemical computation in dendrites involving the controlled complementation of three molecules--Rac1, RhoA and Cdc42 (show CDC42 Antibodies)--that simultaneously ensures signal specificity and primes the system for BDNF (show BDNF Antibodies)-dependent homo- and heterosynaptic plasticity

  3. The transcriptional co-activator MRTF-A (show MKL1 Antibodies) was activated by sphingosine-1-phosphate as assessed by its nuclear accumulation and induction of a RhoA/MRTF-A (show MKL1 Antibodies) luciferase reporter.

  4. In conclusion, these results indicate the sub-chronic ethanol treatment decreased the expression of RhoA in mouse corpus cavernosum

  5. RhoA-PLD1 signaling is involved in acidic extracellular pH-induced matrix metalloproteinase-9 (show MMP9 Antibodies) in mouse metastatic B16-BL6 melanoma cells

  6. Caspase-11 (show CASP4 Antibodies) targets cofilin (show CFL1 Antibodies) via the RhoA GTPase, whereas caspase-1 (show CASP1 Antibodies) engages the Slingshot phosphatase

  7. RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix.

  8. TcdB proteins target Rac (show AKT1 Antibodies), Cdc42 (show CDC42 Antibodies), Rap (show LRPAP1 Antibodies), and R-Ras and glucosylates RhoA.

  9. In cultured neonatal cardiac fibroblasts, p63RhoGEF regulated the angiotensin II (Ang II)-dependent RhoA activation, the activation of the serum response factor, and the expression and secretion of CTGF (show CTGF Antibodies).

  10. Inhibition of the RhoA/Rock2 (show ROCK2 Antibodies) kinase pathway prevents lipopolysaccharide-induced hyperalgesia and the release of TNF-alpha (show TNF Antibodies) and IL-1beta (show IL1B Antibodies) in the mouse spinal cord.

Cow (Bovine) Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. RhoA and membrane fluidity mediates the spatially polarized Src (show SRC Antibodies)/FAK (show PTK2 Antibodies) activation in response to shear stress.

  2. the Lbc (show AKAP13 Antibodies)/alpha-catulin (show CTNNAL1 Antibodies) axis participates in 5-HT (show DDC Antibodies)-induced PASMC mitogenesis and RhoA/ROCK signaling, and may be an interventional target in diseases involving vascular smooth muscle remodeling.

  3. The RhoA/ROCK signaling pathway is an important negative regulator of vascular calcification.

  4. Vascular endothelial-cadherin signals through RhoA and actin cytoskeletal and affects cell-matrix adhesion

  5. Thrombospondin has a role in inducing RhoA inactivation through FAK (show PTK2 Antibodies)-dependent signaling to stimulate focal adhesion disassembly

  6. KCl directly increased Rho and ROCK activities in a concentration-dependent fashion that paralleled closely the effect of KCl on lung smooth muscle tone and [Ca(2 (show CA2 Antibodies)+)](i), as well as the voltage-dependent Ca(2 (show CA2 Antibodies)+) currents

  7. the Rho-ROCK signal pathway contributes to VEGF-induced hyperpermeability. Myosin light-chain phosphorylation and actin stress fiber formation occur concomitantly with the increase in permeability upon VEGF stimulation.

  8. Formation of polygonal actin network in endothelial cells is a novel rhoA associated response to hypertonic stress.

  9. Cadherins, RhoA and Rac1, have important roles in mechanotransduction and that endothelial and smooth muscle cells use different mechanisms to respond to stretch.

  10. Results indicate that hypergravity induces ATP release and actin reorganization via RhoA activation and FAK (show PTK2 Antibodies) phosphorylation, thereby activating cell proliferation and migration in bovine aortic endothelial cells.

Zebrafish Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Activating Rho could be beneficial to suppress Kras mutant-induced liver malignancies.

RHOA Antigen Profile

Antigen Summary

Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA- DIAPH1 signaling pathway plays an important role in ERBB2- dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.

Alternative names and synonyms associated with RHOA

  • RSA-14-44 protein (RSA-14-44) antibody
  • ras homolog family member A (RHOA) antibody
  • ras homolog family member A (rhoa-b) antibody
  • ras homolog family member A (rhoa) antibody
  • ras homolog family member A (Rhoa) antibody
  • ras homolog family member A (rhoa-a) antibody
  • ras homolog gene family, member A (Rhoa) antibody
  • ras homolog gene family, member A (RHOA) antibody
  • ras homolog gene family, member Aa (rhoaa) antibody
  • ARH12 antibody
  • Arha antibody
  • Arha1 antibody
  • Arha2 antibody
  • RHO1 antibody
  • RHO12 antibody
  • Rhoa antibody
  • RHOH12 antibody
  • wu:fa66g04 antibody
  • wu:fb26g07 antibody
  • xrhoa antibody
  • zgc:66058 antibody
  • zgc:85805 antibody

Protein level used designations for RHOA

ras homolog gene family, member A , transforming protein RhoA , aplysia ras-related homolog A2 , Aplysia ras-related homolog 12 , h12 , oncogene RHO H12 , rho cDNA clone 12 , small GTP binding protein RhoA , plysia ras-related homolog A2 , rho1 GTP-binding protein , Rho A , Ras family member A , Rho family GTPase , aplysia ras-related homolog A , aplysia ras-related homolog A1 , ras homolog A1 , ras homolog A2 , ras homolog gene family, member A1 , ras homolog gene family, member A2 , gb , p21 , RhoA GTPase

297173 Rattus norvegicus
100302078 Ovis aries
380133 Xenopus laevis
448080 Xenopus (Silurana) tropicalis
387 Homo sapiens
117273 Rattus norvegicus
403954 Canis lupus familiaris
379416 Xenopus laevis
396849 Sus scrofa
11848 Mus musculus
338049 Bos taurus
395442 Gallus gallus
406411 Danio rerio
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