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anti-Human TUBB1 Antibodies:
anti-Mouse (Murine) TUBB1 Antibodies:
anti-Rat (Rattus) TUBB1 Antibodies:
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Human Polyclonal TUBB1 Primary Antibody for EIA, WB - ABIN955390
Antón, González-Conejero, Roldán, Quiroga, Sánchez-Vega, Corral, Vicente, Mezzano: Study of 18 functional hemostatic polymorphisms in mucocutaneous bleeding disorders. in Annals of hematology 2010
Show all 4 references for ABIN955390
Mutations in either TUBB (show TUBB2A Antibodies) or MAPRE2 (show MAPRE2 Antibodies) cause circumferential skin creases Kunze type.
TUBB1 R307H SNP is significantly associated with the degree of thrombocytopenia in congenital and acquired platelet disorders, and may affect platelets by altering microtubule behavior.
Data indicate that ABCB1 (show ABCB1 Antibodies) protein, beta tubulin (show TUBB Antibodies) I and III (betaI, and betaIII tubulin (show TUBB3 Antibodies)) might contribute to the multidrug resistance (MDR) of MCF7/DOC and be potential therapeutic targets for overcoming MDR of breast cancer.
TUBB1 mutation disrupting microtubule assembly impairs proplatelet formation and results in congenital macrothrombocytopenia.
our findings define beta-tubulin (show TUBB Antibodies) VI as a hematologic isotype with significant genetic variation in humans that may affect the myelosuppresive action of microtubule-binding drugs
homozygous status of P43 (show AIMP1 Antibodies) genetic polymorphism causes alterations in platelet ultrastructure
human tumor cells can acquire spontaneous mutations in beta1-tubulin (show TUBB Antibodies) that cause resistance to paclitaxel
Studies show that BFBTS bound and modified beta-tubulin (show TUBB Antibodies) at residue Cys12, forming beta-tubulin (show TUBB Antibodies)-SS-fluorobenzyl.
SLPI (show SLPI Antibodies) localizes in part along the megakaaryocyte and platelet cytoskeleton by virtue of specific interactions with beta1 tubulin (show TUBB Antibodies).
the platelet Q43P beta1-tubulin (show TUBB Antibodies) substitution is frequent in the healthy population and may protect men against arterial thrombosis
RanBP10 (show RANBP10 Antibodies) inhibits premature microtubule polymerization of beta1-tubulin (show TUBB Antibodies) and plays a pivotal role in thrombus stabilization.
The hematopoietic-specific Hbeta1 (show KCNMB1 Antibodies) tubulin (show TUBB Antibodies) isotype naturally encodes Ibeta236 and is insensitive to 2-methoxyestradiol.
findings highlight the essential requirements of the megakaryocyte/platelet-restricted beta1-tubulin (show TUBB Antibodies) isoform in platelet structure
The conserved four-helix bundle of c-Cbl's tyrosine kinase (show TYRO3 Antibodies) binding domain bound to beta-tubulin (show TUBB Antibodies), and both c-Cbl (show CBL Antibodies) and Cbl-b displaced HDAC6 (show HDAC6 Antibodies).
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.
Tubulin beta-1 chain
, tubulin, beta 1
, tubulin beta-1 chain
, tubulin, beta family 1
, tubulin beta-1 chain-like
, beta-tubulin class-VI
, tubulin beta-6 chain
, tubulin, beta 3
, beta tubulin 1, class VI
, class VI beta-tubulin