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study associates mutations in TUBB2A with the spectrum of "tubulinopathy" phenotypes
This is the first study showing that paclitaxel neuropathy risk is influenced by polymorphisms regulating the expression of a beta (show SUCLA2 Proteins)-tubulin (show TUBB Proteins) gene.
Class II beta-tubulin (show TUBB Proteins) may be very useful for immunohistochemical diagnosis of classical Hodgkin's lymphoma.
Data suggest that the increased betaII- and betaIII-tubulin (show TUBB3 Proteins) contributed significantly to the resistance phenotype.
Data show that connexin 43 (cx43 (show GJA1 Proteins)) binds alpha-tubulin (show TUBA4A Proteins) equally well as beta-tubulin (show TUBB Proteins), and that ZO-1 (show TJP1 Proteins) binds directly to Cx43 (show GJA1 Proteins).
Mutations of the beta-tubulin (show TUBB Proteins) gene, which might be a contraindication for chemotherapy based on taxans, were very rare events in gastric cancer.
nuclear beta(II)-tubulin (show TUBB Proteins) can modulate Notch (show NOTCH1 Proteins) signaling through interaction with notch1 (show NOTCH1 Proteins) receptor intracellular domain in cancer cells
Smad3 (show SMAD3 Proteins) was bound to beta2-tubulin (show TUBB Proteins) in a TGF-beta1 (show TGFB1 Proteins)/cGMP-dependent manner.
The axial elastic modulus of tubulin (show TUBB Proteins) diminishes as the length of the monomer increases.
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain (By similarity).
tubulin, beta 2A
, tubulin beta-3 chain
, Tubulin beta-3 chain
, class IIa beta-tubulin
, tubulin beta class IIa
, tubulin beta-2A chain
, tubulin, beta polypeptide 2
, beta 5-tubulin
, tubulin beta chain
, tubulin beta-5 chain
, tubulin, beta polypeptide
, tubulin, beta 2
, c(beta)7 tubulin
, tubulin beta 4'
, tubulin beta-7 chain
, tubulin beta-2B chain
, tubulin, beta 2B class IIb