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MPK6 (show MAPK6 ELISA Kits) phosphorylates EB1c, but not EB1a, and has a role in maintaining regular planes of cell division under stress conditions.
Authors report that the only viral nonstructural protein able to reproduce the loss of gamma-tubulin from the microtubule organizing center and the loss of integrity of the microtubule system is Foot-and-mouth disease virus 3C(pro).
a causative link between altered function of AURKA-HMMR-TPX2-TUBG1 and breast carcinogenesis in BRCA1/2 mutation carriers
Results show that CUL4A (show CUL4A ELISA Kits)- and CUL4B (show CUL4B ELISA Kits)-mediated polyubiquitination of gamma-tubulin for its degradation.
In this study, the molecular basis of interaction between two lateral gamma-tubulin units within the gamma-tubulin ring complex were elucidated by making extensive use of molecular mechanics and molecular dynamics techniques.
Gamma tubulin expression was associated with patients' age, astrocytoma grade, respectability, patient survival and performance. These factors may be important prognostic indicators for patients with astrocytomas.
Recombinant gamma-tubulin can be phosphorylated by Cdk1 (show CDK1 ELISA Kits)-cyclin B or Brsk1 (show BRSK1 ELISA Kits) and dephosphorylated by Ppp4c (show PPP4C ELISA Kits)-R2-R3A in vitro.
Nek9 (show NEK9 ELISA Kits) phosphorylates NEDD1 (show NEDD1 ELISA Kits) on Ser377 driving its recruitment and thereby that of gamma-tubulin to the centrosome in mitotic cells.
Our results reveal for the first time an increased expression of TUBG1 and TUBG2 (show TUBG2 ELISA Kits) in lung cancer
overexpression of Cdk1 (show CDK1 ELISA Kits) or BRCA1 greatly expands the gamma-tubulin coating of microtubules, suggesting that the microtubule-bound gamma-tubulin is involved in DNA damage response.
in transformed as well as in non-transformed interphase mammalian cells gamma-tubulin is present not only in cytoplasm but also in nuclei and nucleoli where it can be translocated during mitosis
These results thus report for the first time the identification of Cep70 (show CEP70 ELISA Kits) as an important centrosomal protein that interacts with gamma-tubulin and underscore its critical role in the regulation of mitotic spindle assembly.
Fodrin is a regulatory transporter of gamma-tubulin to the centrosomes for normal progression of mitosis.
Data suggest that localization of Tubg1 (and Plk1 (show PLK1 ELISA Kits) [polo-like kinase 1 (show PLK1 ELISA Kits)]) to spindle poles during oocyte meiotic maturation/oogenesis (metaphase I/II) requires participation of Uchl5ip/Haus7 (HAUS augmin-like complex subunit 7 (show HAUS7 ELISA Kits)).
a direct interaction with NEDD1 (show NEDD1 ELISA Kits) regulates gamma-tubulin recruitment to the centrosome
Gamma-tubulin is a key regulator of asymmetric cytokinesis in mouse oocytes.
pPKCdelta(Thr505) interacts with MTOC-associated proteins pericentrin (show PCNT ELISA Kits) and gamma-tubulin, and plays a role in meiotic spindle organization in oocytes
Results suggest that Fyn (show FYN ELISA Kits) and PI3K might take part in the modulation of membrane-associated gamma-tubulin activities.
SADB (show BRSK1 ELISA Kits) kinase activity controls centrosome homeostasis by regulating phosphorylation of gamma-tubulin.
Data show that depletion of either gamma-tubulin or XMAP215 (show CKAP5 ELISA Kits) was partially rescued by adding back XMAP215 (show CKAP5 ELISA Kits), but not by adding any of the other factors.
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.
Tubulin gamma-3 chain
, tubulin gamma-1 chain
, gamma-tubulin complex component 1
, tubulin, gamma polypeptide
, gamma tubulin